Published in J Biol Chem on July 16, 1999
Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2. Proc Natl Acad Sci U S A (2001) 2.93
Molecular dynamics simulations reveal a disorder-to-order transition on phosphorylation of smooth muscle myosin. Biophys J (2007) 1.27
Site-directed spin labeling reveals a conformational switch in the phosphorylation domain of smooth muscle myosin. Proc Natl Acad Sci U S A (2005) 1.20
Holding two heads together: stability of the myosin II rod measured by resonance energy transfer between the heads. Proc Natl Acad Sci U S A (2002) 1.00
Smooth muscle heavy meromyosin phosphorylated on one of its two heads supports force and motion. J Biol Chem (2009) 0.97
Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK). J Biol Chem (2009) 0.97
Broad disorder and the allosteric mechanism of myosin II regulation by phosphorylation. Proc Natl Acad Sci U S A (2011) 0.85
Structural dynamics of muscle protein phosphorylation. J Muscle Res Cell Motil (2012) 0.85
Regulatory and catalytic domain dynamics of smooth muscle myosin filaments. Biochemistry (2006) 0.80
Molecular mechanism of telokin-mediated disinhibition of myosin light chain phosphatase and cAMP/cGMP-induced relaxation of gastrointestinal smooth muscle. J Biol Chem (2012) 0.80
Kinetic and motor functions mediated by distinct regions of the regulatory light chain of smooth muscle myosin. Biochim Biophys Acta (2009) 0.77
The function of myosin and myosin light chain kinase phosphorylation in smooth muscle. Annu Rev Pharmacol Toxicol (1985) 4.80
Dedicated myosin light chain kinases with diverse cellular functions. J Biol Chem (2000) 3.89
Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle. Proc Natl Acad Sci U S A (1998) 3.00
Myosin light chain phosphorylation in vertebrate striated muscle: regulation and function. Am J Physiol (1993) 2.81
Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy. Proc Natl Acad Sci U S A (2000) 2.49
ADP release produces a rotation of the neck region of smooth myosin but not skeletal myosin. Nat Struct Biol (1996) 2.18
Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy. Proc Natl Acad Sci U S A (1996) 2.06
Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies. Nat Cell Biol (1999) 2.01
Regulation of smooth muscle contractile elements by second messengers. Annu Rev Physiol (1989) 1.98
The effect of myosin phosphorylation on the contractile properties of skinned rabbit skeletal muscle fibers. J Biol Chem (1985) 1.95
Alteration of cross-bridge kinetics by myosin light chain phosphorylation in rabbit skeletal muscle: implications for regulation of actin-myosin interaction. Proc Natl Acad Sci U S A (1990) 1.87
Myosin light chain phosphorylation affects the structure of rabbit skeletal muscle thick filaments. Biophys J (1996) 1.75
Measurement of cyclic 3',5'-denosine monophosphate by the activation of skeletal muscle protein kinase. J Biol Chem (1971) 1.72
Phosphorylation of the inhibitor component of troponin by phosphorylase kinase. J Biol Chem (1972) 1.71
Myosin light chain kinases. J Muscle Res Cell Motil (1997) 1.67
Charge replacement near the phosphorylatable serine of the myosin regulatory light chain mimics aspects of phosphorylation. Proc Natl Acad Sci U S A (1994) 1.67
Phosphorylation of myosin in permeabilized mammalian cardiac and skeletal muscle cells. Am J Physiol (1986) 1.66
Molecular characterization of a mammalian smooth muscle myosin light chain kinase. J Biol Chem (1991) 1.59
nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle. Physiol Genomics (2000) 1.54
Familial hypertrophic cardiomyopathy mutations in the regulatory light chains of myosin affect their structure, Ca2+ binding, and phosphorylation. J Biol Chem (2000) 1.50
The amino acid sequences of the phosphorylated sites in troponin-I from rabbit skeletal muscle. FEBS Lett (1974) 1.49
Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle. Am J Physiol (1998) 1.46
Activation of skeletal muscle myosin light chain kinase by calcium(2+) and calmodulin. Biochemistry (1980) 1.43
Structures of calmodulin and a functional myosin light chain kinase in the activated complex: a neutron scattering study. Biochemistry (1997) 1.41
Phosphorylation of cardiac troponin by cyclic adenosine 3':5'-monophosphate-dependent protein kinase. J Biol Chem (1977) 1.41
Ca(2+)-dependent phosphorylation of myosin light chain kinase decreases the Ca2+ sensitivity of light chain phosphorylation within smooth muscle cells. J Biol Chem (1994) 1.40
Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca2+ binding sites. J Biol Chem (1993) 1.35
Structure and regulation of calcium/calmodulin-dependent protein kinases. Chem Rev (2001) 1.35
Myosin light chain phosphorylation in fast and slow skeletal muscles in situ. Am J Physiol (1984) 1.31
Different phosphorylated forms of myosin in contracting tracheal smooth muscle. J Biol Chem (1986) 1.30
GTP gamma S-dependent regulation of smooth muscle contractile elements. Am J Physiol (1992) 1.29
Localization and activity of myosin light chain kinase isoforms during the cell cycle. J Cell Biol (2000) 1.29
Measurement of chemical phosphate in proteins. Methods Enzymol (1983) 1.29
Activation of smooth muscle contraction: relation between myosin phosphorylation and stiffness. Science (1986) 1.27
Myosin light chain phosphorylation and phosphorylase A activity in rat extensor digitorum longus muscle. Biochem Biophys Res Commun (1979) 1.27
Sites phosphorylated in myosin light chain in contracting smooth muscle. J Biol Chem (1988) 1.27
Identification of a calcium/calmodulin-dependent protein kinase that phosphorylates the Neurospora circadian clock protein FREQUENCY. J Biol Chem (2001) 1.26
Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles. Physiol Genomics (2001) 1.25
Phosphorylation of myosin in perfused rabbit and rat hearts. Am J Physiol (1980) 1.25
Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide. FEBS Lett (1998) 1.23
Phosphorylation of myosin light chain kinase by the multifunctional calmodulin-dependent protein kinase II in smooth muscle cells. J Biol Chem (1992) 1.20
Myosin light chain phosphorylation-dephosphorylation in mammalian skeletal muscle. Am J Physiol (1982) 1.18
Kinetics of smooth muscle heavy meromyosin with one thiophosphorylated head. J Biol Chem (2000) 1.18
Frequency-dependent myosin light chain phosphorylation in isolated myocardium. J Mol Cell Cardiol (1986) 1.17
Myosin phosphorylation, force, and maximal shortening velocity in neurally stimulated tracheal smooth muscle. Am J Physiol (1985) 1.16
Effects of pH, ionic strength, and temperature on activation by calmodulin an catalytic activity of myosin light chain kinase. Biochemistry (1982) 1.15
Identification of a novel actin binding motif in smooth muscle myosin light chain kinase. J Biol Chem (1999) 1.13
Contractile elements and myosin light chain phosphorylation in myometrial tissue from nonpregnant and pregnant women. J Clin Invest (1993) 1.12
Structural and functional responses of mammalian thick filaments to alterations in myosin regulatory light chains. J Struct Biol (1998) 1.12
Photochemical mapping of the active site of myosin. Philos Trans R Soc Lond B Biol Sci (1992) 1.10
Properties of filament-bound myosin light chain kinase. J Biol Chem (1999) 1.07
Substrate specificity of myosin light chain kinases. J Biol Chem (1992) 1.07
Phosphorylation of smooth muscle myosin heavy and light chains. Effects of phorbol dibutyrate and agonists. J Biol Chem (1989) 1.07
Domain characterization of rabbit skeletal muscle myosin light chain kinase. J Biol Chem (1990) 1.06
Calcium dependence of myosin light chain phosphorylation in smooth muscle cells. J Biol Chem (1988) 1.06
Regulation of phosphorylase activation in skeletal muscle in vivo. J Biol Chem (1971) 1.05
The binding of fd gene 5 protein to polydeoxynucleotides: evidence from CD measurements for two binding modes. J Biomol Struct Dyn (1986) 1.04
Incidence and natural history of left ventricular thrombus following anterior wall acute myocardial infarction. Am J Cardiol (1997) 1.04
Phosphorylation of skeletal muscle contractile proteins in vivo. Biochem Biophys Res Commun (1977) 1.03
Plant chimeric Ca2+/Calmodulin-dependent protein kinase. Role of the neural visinin-like domain in regulating autophosphorylation and calmodulin affinity. J Biol Chem (2000) 1.03
Binding of myosin light chain kinase to cellular actin-myosin filaments. J Biol Chem (1997) 1.03
A molecular mechanism for autoinhibition of myosin light chain kinases. J Biol Chem (1993) 1.03
Changes in interfilament spacing mimic the effects of myosin regulatory light chain phosphorylation in rabbit psoas fibers. J Struct Biol (1998) 1.02
Phosphorylation of contractile proteins in relation to muscle function. Adv Cyclic Nucleotide Res (1980) 1.02
Interference with lysosomal proteolysis fails to reduce cardiac myosin degradation. Biochem Biophys Res Commun (1980) 1.00
Structure and function of the 10 S conformation of smooth muscle myosin. J Biol Chem (1996) 1.00
Functional and molecular adaptations in skeletal muscle of myoglobin-mutant mice. Am J Physiol Cell Physiol (2001) 0.99
Okadaic acid uncouples myosin light chain phosphorylation and tension in smooth muscle. FEBS Lett (1990) 0.99
Genetically engineered calmodulins differentially activate target enzymes. J Biol Chem (1986) 0.98
Regulation of myosin light chain and phosphorylase phosphorylation in tracheal smooth muscle. J Biol Chem (1982) 0.98
Myosin phosphorylation during contraction and relaxation of tracheal smooth muscle. J Biol Chem (1980) 0.98
The effect of low frequency stimulation on myosin light chain phosphorylation in skeletal muscle. J Biol Chem (1982) 0.98
Regulation of contraction by myosin phosphorylation. A comparison between smooth and skeletal muscles. Biochem Pharmacol (1980) 0.97
Molecular characterization of rat skeletal muscle myosin light chain kinase. Am J Physiol (1989) 0.97
A new method to specifically label thiophosphorylatable proteins with extrinsic probes. Labeling of serine-19 of the regulatory light chain of smooth muscle myosin. Bioconjug Chem (1992) 0.97
Myosin light chain kinase: functional domains and structural motifs. Acta Physiol Scand (1998) 0.96
Myosin phosphorylation regulates the ATPase activity of permeable skeletal muscle fibers. FEBS Lett (1982) 0.96
Biochemical events associated with activation of smooth muscle contraction. J Biol Chem (1988) 0.96
Effects of cGMP on [Ca2+]i, myosin light chain phosphorylation, and contraction in human myometrium. Am J Physiol (1991) 0.96
Biochemical properties of chimeric skeletal and smooth muscle myosin light chain kinases. J Biol Chem (1992) 0.96
Cytoplasmic Ca2+ is a primary determinant for myosin phosphorylation in smooth muscle cells. J Biol Chem (1989) 0.95
Myosin light chain kinases and myosin phosphorylation in skeletal muscle. Adv Enzyme Regul (1985) 0.95
Identification of basic residues involved in activation and calmodulin binding of rabbit smooth muscle myosin light chain kinase. J Biol Chem (1992) 0.94
Phosphorylation kinetics of skeletal muscle myosin and the effect of phosphorylation on actomyosin adenosinetriphosphatase activity. Biochemistry (1984) 0.94
Phosphorylation regulates the ADP-induced rotation of the light chain domain of smooth muscle myosin. Biochemistry (1999) 0.93
Phosphorylation of myosin light chain and phosphorylase in tracheal smooth muscle in response to KCl and carbachol. Mol Pharmacol (1984) 0.93
Dephosphorylation of the inhibitor component of troponin by phosphorylase phosphatase. J Biol Chem (1972) 0.93
Neuronal nitric oxide synthase localizes through multiple structural motifs to the sarcolemma in mouse myotubes. FEBS Lett (2000) 0.92
Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction. J Cell Biol (2001) 0.92
The role of myosin light chain kinase phosphorylation in beta-adrenergic relaxation of tracheal smooth muscle. Mol Pharmacol (1983) 0.91
Phosphorylation of rabbit skeletal muscle myosin in situ. J Cell Physiol (1985) 0.91
Localization of an actin binding domain in smooth muscle myosin light chain kinase. Mol Cell Biochem (1997) 0.91
Myosin light chain kinase phosphorylation in swine carotid artery contraction and relaxation. Am J Physiol (1995) 0.91
Myosin light chain phosphorylation and isometric twitch potentiation in intact human muscle. Pflugers Arch (1985) 0.90
Myosin light chain kinase binding to actin filaments. FEBS Lett (2000) 0.90