Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs.

PubWeight™: 1.66‹?› | Rank: Top 3%

🔗 View Article (PMC 1567499)

Published in Environ Health Perspect on August 01, 1999

Authors

A Brouwer1, M P Longnecker, L S Birnbaum, J Cogliano, P Kostyniak, J Moore, S Schantz, G Winneke

Author Affiliations

1: Division of Toxicology, Department of Food Technology and Nutritional Sciences, Wageningen Agricultural University and Research Center, The Netherlands. bram.brouwer@algemeen.tox.wau.nl

Articles citing this

Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev (2009) 9.60

Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment. Environ Health Perspect (2003) 2.41

Impact of pesticides use in agriculture: their benefits and hazards. Interdiscip Toxicol (2009) 2.22

Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis. Environ Health Perspect (2008) 1.86

Influence of the consumption of fatty Baltic Sea fish on plasma levels of halogenated environmental contaminants in Latvian and Swedish men. Environ Health Perspect (2000) 1.71

Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go. Toxicol Sci (2008) 1.71

Potential exposure to PCBs, DDT, and PBDEs from sport-caught fish consumption in relation to breast cancer risk in Wisconsin. Environ Health Perspect (2004) 1.47

Toxic threats to neurologic development of children. Environ Health Perspect (2001) 1.39

Fetal exposure to PCBs and their hydroxylated metabolites in a Dutch cohort. Environ Health Perspect (2004) 1.22

In utero exposure to dioxins and polychlorinated biphenyls and its relations to thyroid function and growth hormone in newborns. Environ Health Perspect (2005) 1.16

Crystallographic analysis of a hydroxylated polychlorinated biphenyl (OH-PCB) bound to the catalytic estrogen binding site of human estrogen sulfotransferase. Environ Health Perspect (2003) 1.15

Community health profile of Windsor, Ontario, Canada: anatomy of a Great Lakes area of concern. Environ Health Perspect (2001) 1.11

Impact of polychlorinated biphenyls contamination on estrogenic activity in human male serum. Environ Health Perspect (2005) 1.09

Metabolism and metabolites of polychlorinated biphenyls. Crit Rev Toxicol (2015) 1.09

Organochlorines, lead, and mercury in Akwesasne Mohawk youth. Environ Health Perspect (2003) 1.08

Predictors of serum dioxin levels among adolescent boys in Chapaevsk, Russia: a cross-sectional pilot study. Environ Health (2005) 1.07

The effects of prenatal PCBs on adult female paced mating reproductive behaviors in rats. Horm Behav (2006) 1.02

Levels of persistent organic pollutant and their predictors among young adults. Chemosphere (2011) 1.01

Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin. Environ Health Perspect (2013) 1.00

Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts. Environ Health (2003) 0.97

Global gene expression and Ingenuity biological functions analysis on PCBs 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities. Environ Int (2011) 0.96

Animal food intake and cooking methods in relation to endometrial cancer risk in Shanghai. Br J Cancer (2006) 0.94

Relationships between PCBs and thyroid hormones and retinol in female and male polar bears. Environ Health Perspect (2004) 0.94

PCBs exert an estrogenic effect through repression of the Wnt7a signaling pathway in the female reproductive tract. Environ Health Perspect (2006) 0.94

Xenoestrogenic activity in blood of European and Inuit populations. Environ Health (2006) 0.92

Body burdens of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls and their relations to estrogen metabolism in pregnant women. Environ Health Perspect (2006) 0.89

Omega-3 fatty acids, genetic variants in COX-2 and prostate cancer. J Nutrigenet Nutrigenomics (2009) 0.88

Assessing the effects of endocrine disruptors in the National Children's Study. Environ Health Perspect (2003) 0.87

Differential gene expression and a functional analysis of PCB-exposed children: understanding disease and disorder development. Environ Int (2011) 0.86

Three stages of a biofilm community developing at the liquid-liquid interface between polychlorinated biphenyls and water. Appl Environ Microbiol (2005) 0.85

The relevance of serum levels of long chain omega-3 polyunsaturated fatty acids and prostate cancer risk: A meta-analysis. Can Urol Assoc J (2013) 0.84

Facing the challenge of data transfer from animal models to humans: the case of persistent organohalogens. Environ Health (2008) 0.83

Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. Environ Res (2015) 0.80

Blood level omega-3 Fatty acids as risk determinant molecular biomarker for prostate cancer. Prostate Cancer (2013) 0.80

An approach to assessment of endocrine disruption in the National Children's Study. Environ Health Perspect (2003) 0.79

Influence of Low-Level Prenatal Exposure to PCDD/Fs and PCBs on Empathizing, Systemizing and Autistic Traits: Results from the Duisburg Birth Cohort Study. PLoS One (2015) 0.79

Effects of Chinese domestic polychlorinated biphenyls (PCBs) on gonadal differentiation in Xenopus laevis. Environ Health Perspect (2003) 0.78

Environmental Polychlorinated Biphenyl Exposure and Breast Cancer Risk: A Meta-Analysis of Observational Studies. PLoS One (2015) 0.78

Xenobiotic action on steroid hormone synthesis and sulfonation the example of lead and polychlorinated biphenyls. Int Arch Occup Environ Health (2008) 0.77

Accidental exposure to polychlorinated biphenyls (PCB) in waste cargo after heavy seas. Global waste transport as a source of PCB exposure. Int Arch Occup Environ Health (2013) 0.77

Long-term effects of neonatal exposure to hydroxylated polychlorinated biphenyls in the BALB/cCrgl mouse. Environ Health Perspect (2005) 0.76

Estrogen-like activity of seafood related to environmental chemical contaminants. Environ Health (2006) 0.76

Canola oil is an excellent vehicle for eliminating pesticide residues in aqueous ginseng extract. J Ginseng Res (2015) 0.75

Policy statements adopted by the Governing Council of the American Public Health Association, November 15, 2000. Am J Public Health (2001) 0.75

Maternal serum levels of perfluoroalkyl substances and organochlorines and indices of fetal growth: a Scandinavian case-cohort study. Pediatr Res (2016) 0.75

Factors Associated with Maternal Serum Levels of Perfluoroalkyl Substances and Organochlorines: A Descriptive Study of Parous Women in Norway and Sweden. PLoS One (2016) 0.75

Endocrine Disrupting Chemicals and Endometrial Cancer: An Overview of Recent Laboratory Evidence and Epidemiological Studies. Int J Environ Res Public Health (2017) 0.75

Mechanistic insights into the specificity of human cytosolic sulfotransferase 2A1 (hSULT2A1) for hydroxylated polychlorinated biphenyls through the use of fluoro-tagged probes. Environ Sci Pollut Res Int (2015) 0.75

Articles cited by this

(truncated to the top 100)

Blood levels of organochlorine residues and risk of breast cancer. J Natl Cancer Inst (1993) 8.11

Plasma organochlorine levels and the risk of breast cancer. N Engl J Med (1997) 7.02

Breast cancer and serum organochlorines: a prospective study among white, black, and Asian women. J Natl Cancer Inst (1994) 5.92

Intellectual impairment in children exposed to polychlorinated biphenyls in utero. N Engl J Med (1996) 5.72

Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats. Toxicol Appl Pharmacol (1978) 4.62

Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit Rev Toxicol (1994) 4.59

Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes. Mol Pharmacol (1988) 3.41

Effects of in utero exposure to polychlorinated biphenyls and related contaminants on cognitive functioning in young children. J Pediatr (1990) 3.37

Neonatal effects of transplacental exposure to PCBs and DDE. J Pediatr (1986) 2.70

Quantitative PCB standards for electron capture gas chromatography. J Chromatogr Sci (1973) 2.68

The human health effects of DDT (dichlorodiphenyltrichloroethane) and PCBS (polychlorinated biphenyls) and an overview of organochlorines in public health. Annu Rev Public Health (1997) 2.44

The effect of intrauterine PCB exposure on visual recognition memory. Child Dev (1985) 2.36

Polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in human milk: effects of maternal factors and previous lactation. Am J Public Health (1986) 2.36

Interactions of persistent environmental organohalogens with the thyroid hormone system: mechanisms and possible consequences for animal and human health. Toxicol Ind Health (1998) 2.24

Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants. Pediatr Res (1994) 2.18

Developmental and reproductive toxicity of dioxins and related compounds: cross-species comparisons. Crit Rev Toxicol (1993) 2.11

Polychlorinated biphenyls and the developing nervous system: cross-species comparisons. Neurotoxicol Teratol (1990) 1.99

Estrogenic and antiestrogenic actions of PCBs in the female rat: in vitro and in vivo studies. Reprod Toxicol (1993) 1.89

Effects of polychlorinated biphenyl/dioxin exposure and feeding type on infants' mental and psychomotor development. Pediatrics (1996) 1.85

Effects of perinatal polychlorinated biphenyls and dichlorodiphenyl dichloroethene on later development. J Pediatr (1991) 1.81

Development after exposure to polychlorinated biphenyls and dichlorodiphenyl dichloroethene transplacentally and through human milk. J Pediatr (1988) 1.80

A nested case-control study of non-Hodgkin lymphoma and serum organochlorine residues. Lancet (1997) 1.79

Reproductive failure in common seals feeding on fish from polluted coastal waters. Nature (1987) 1.70

Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships. Toxicol Appl Pharmacol (1997) 1.61

Perinatal exposure to polychlorinated biphenyls and dioxins and its effect on neonatal neurological development. Early Hum Dev (1995) 1.56

Structure-dependent, competitive interaction of hydroxy-polychlorobiphenyls, -dibenzo-p-dioxins and -dibenzofurans with human transthyretin. Chem Biol Interact (1993) 1.52

Induction of liver tumor in Sherman strain female rats by polychlorinated biphenyl aroclor 1260. J Natl Cancer Inst (1975) 1.52

The relation of polychlorinated biphenyls to birth weight and gestational age in the offspring of occupationally exposed mothers. Am J Epidemiol (1989) 1.50

An improved analysis for chlorinated pesticides and polychlorinated biphenyls (PCBs) in human and bovine sera using solid-phase extraction. J Anal Toxicol (1997) 1.48

Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: quantitative structure-activity relationships. Toxicol Appl Pharmacol (1993) 1.40

Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats. Toxicol Appl Pharmacol (1993) 1.34

Binding of a metabolite of 3,4,3',4'-tetrachlorobiphenyl to transthyretin reduces serum vitamin A transport by inhibiting the formation of the protein complex carrying both retinol and thyroxin. Toxicol Appl Pharmacol (1986) 1.32

Comparative carcinogenicity in Sprague-Dawley rats of the polychlorinated biphenyl mixtures Aroclors 1016, 1242, 1254, and 1260. Toxicol Sci (1998) 1.31

Environmental organochlorine exposure and postmenopausal breast cancer risk. Cancer Epidemiol Biomarkers Prev (1998) 1.30

Effects of pre- and postnatal exposure to chlorinated dioxins and furans on human neonatal thyroid hormone concentrations. Environ Health Perspect (1993) 1.29

Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat. Toxicol Lett (1993) 1.29

Uterotrophic activity of polychlorinated biphenyls (PCB) and induction of precocious reproductive aging in neonatally treated female rats. Environ Res (1978) 1.28

Alterations in rat brain thyroid hormone status following pre- and postnatal exposure to polychlorinated biphenyls (Aroclor 1254). Toxicol Appl Pharmacol (1996) 1.26

Environmental endocrine modulators and human health: an assessment of the biological evidence. Crit Rev Toxicol (1998) 1.25

Antiestrogenic activity of hydroxylated polychlorinated biphenyl congeners identified in human serum. Toxicol Appl Pharmacol (1997) 1.24

Quantitation of polychlorinated biphenyl residues by electron capture gas-liquid chromatography: reference material characterization and preliminary study. J Assoc Off Anal Chem (1978) 1.24

In vitro inhibition of thyroid hormone sulfation by hydroxylated metabolites of halogenated aromatic hydrocarbons. Chem Res Toxicol (1998) 1.22

Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Neurotoxicol Teratol (1989) 1.21

Correlations among polychlorinated biphenyls, dioxins, and furans in humans. Am J Ind Med (1999) 1.20

Exposure to TCDD during development permanently alters reproductive function in male Long Evans rats and hamsters: reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring with normal androgenic status. Toxicol Appl Pharmacol (1995) 1.20

Cancer mortality among electric utility workers exposed to polychlorinated biphenyls. Occup Environ Med (1997) 1.20

Polychlorinated biphenyls in blood plasma among Swedish female fish consumers in relation to low birth weight. Am J Epidemiol (1998) 1.17

A quantitative assessment of thyroid histopathology of herring gulls (Larus argentatus) from the Great Lakes and a hypothesis on the causal role of environmental contaminants. J Wildl Dis (1986) 1.17

Different competition of thyroxine binding to transthyretin and thyroxine-binding globulin by hydroxy-PCBs, PCDDs and PCDFs. Eur J Pharmacol (1994) 1.15

Validated extraction and cleanup procedures for polychlorinated biphenyls and DDE in human body fluids and infant formula. J Assoc Off Anal Chem (1984) 1.10

The uterotropic activity of commercial and isomerically-pure chlorobiphenyls in the rat. Res Commun Chem Pathol Pharmacol (1974) 1.09

Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats. Toxicol Appl Pharmacol (1994) 1.09

Molecular interactions of toxic chlorinated dibenzo-p-dioxins and dibenzofurans with thyroxine binding prealbumin. J Med Chem (1985) 1.07

Hydroxylated polychlorinated biphenyl metabolites are anti-estrogenic in a stably transfected human breast adenocarcinoma (MCF7) cell line. Toxicol Appl Pharmacol (1997) 1.07

Standardization of a method for the routine analysis of polychlorinated biphenyl congeners and selected pesticides in human serum and milk. J Anal Toxicol (1998) 1.07

Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment. Eur J Pharmacol (1995) 1.06

Inhibition of thyroid hormone transport in plasma of rats by polychlorinated biphenyls. Arch Toxicol Suppl (1989) 1.06

Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions. Endocrinology (1993) 1.06

Binding of a 3,3', 4,4'-tetrachlorobiphenyl (CB-77) metabolite to fetal transthyretin and effects on fetal thyroid hormone levels in mice. Toxicology (1996) 1.06

Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155). Environ Health Perspect (1997) 1.00

Reproductive and thyroid effects of low-level polychlorinated biphenyl (Aroclor 1254) exposure. Fundam Appl Toxicol (1993) 1.00

Hypothyroidism and abnormalities in the kinetics of thyroid hormone metabolism in rats treated chronically with polychlorinated biphenyl and polybrominated biphenyl. Endocrinology (1987) 1.00

Effects of polychlorinated biphenyls (PCBs) and dioxins on growth and development. Hum Exp Toxicol (1994) 1.00

Target cells for the polychlorinated biphenyl metabolite 4,4'-bis(methylsulfonyl)-2,2',5,5'-tetrachlorobiphenyl. Characterization of high affinity binding in rat and mouse lung cytosol. Mol Pharmacol (1985) 0.96

Enhanced thyroxine metabolism and high uptake goiters in rats after a single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Endocrinology (1977) 0.95

Toxicological manifestations of 2,4,5,2',4',5'-, 2,3,6,2',3',6'-, and 3,4,5,3',4',5'-hexachlorobiphenyl and Aroclor 1254 in mink. J Toxicol Environ Health (1985) 0.94

Effects of perinatal PCB exposure on discrimination-reversal learning in monkeys. Neurotoxicol Teratol (1989) 0.93

Effect of polychlorinated biphenyl (PCB) on the thyroid gland of rats. Ultrastructural and biochemical investigations. Am J Pathol (1977) 0.93

Responses of nonhuman primates to a polybrominated biphenyl mixture. Environ Health Perspect (1978) 0.92

Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls. Toxicol Appl Pharmacol (1997) 0.92

Thyroid function in "yusho" patients exposed to polychlorinated biphenyls (PCB). Environ Res (1987) 0.92

Reproductive effects of halogenated aromatic hydrocarbons on nonhuman primates. Ann N Y Acad Sci (1979) 0.92

The neurochemical effects of PCB exposure are age-dependent. Arch Toxicol Suppl (1994) 0.92

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic and uterine estrogen receptor levels in rats. Toxicol Appl Pharmacol (1987) 0.91

Studies of transformer repair workers exposed to PCBs: II. Results of clinical laboratory investigations. Am J Ind Med (1988) 0.91

Effects of some persistent halogenated environmental contaminants on aromatase (CYP19) activity in the human choriocarcinoma cell line JEG-3. Toxicol Appl Pharmacol (1998) 0.91

Fine structural lesions and hormonal alterations in thyroid glands of perinatal rats exposed in utero and by the milk to polychlorinated biphenyls. Am J Pathol (1980) 0.90

Long-term effects on reproductive parameters in female rats after translactational exposure to PCBs. Environ Res (1994) 0.90

In vitro inhibition of thyroid hormone sulfation by polychlorobiphenylols: isozyme specificity and inhibition kinetics. Toxicol Sci (1998) 0.90

Enchanced in vitro hepatic glucuronidation of thyroxine in rats following cutaneous application or ingestion of polychlorinated biphenyls. Can J Physiol Pharmacol (1976) 0.89

Toxic potency of 3,3',4,4',5-pentachlorobiphenyl relative to and in combination with 2,3,7,8-tetrachlorodibenzo-p-dioxin in a subchronic feeding study in the rat. Toxicol Appl Pharmacol (1994) 0.89

Toxic potency of 2,3,3',4,4',5-hexachlorobiphenyl relative to and in combination with 2,3,7,8-tetrachlorodibenzo-p-dioxin in a subchronic feeding study in the rat. Toxicol Appl Pharmacol (1994) 0.89

Neurological condition in 42-month-old children in relation to pre- and postnatal exposure to polychlorinated biphenyls and dioxins. Early Hum Dev (1998) 0.87

Sensitive periods for behavioral toxicity of polychlorinated biphenyls: determination by cross-fostering in rats. Fundam Appl Toxicol (1991) 0.84

Hepatic UDP-glucuronyltransferase(s) activity toward thyroid hormones in rats: induction and effects on serum thyroid hormone levels following treatment with various enzyme inducers. Toxicol Appl Pharmacol (1991) 0.84

Long-term alterations in regional brain serotonin metabolism following maternal polychlorinated biphenyl exposure in the rat. Neurotoxicology (1997) 0.84

A unique change of steroid metabolism in rat liver microsomes induced with highly toxic polychlorinated biphenyl(PCB) and polychlorinated dibenzofuran(PCDF). J Pharmacobiodyn (1982) 0.84

Ultrastructural and functional alterations of the rat thyroid gland produced by polychlorinated biphenyls compared with iodide excess and deficiency, and thyrotropin and thyroxine administration. Virchows Arch B Cell Pathol Incl Mol Pathol (1980) 0.84

Hormonal alterations in female rhesus monkeys fed a diet containing 2, 3,7,8-tetrachlorodibenzo-p-dioxin. Bull Environ Contam Toxicol (1979) 0.84

Estrogenicity of o,p'-DDT in rats. J Agric Food Chem (1971) 0.84

Effect of postnatal exposure to polychlorinated biphenyls on adult male reproductive function. Environ Res (1983) 0.83

Biliary excretion of 125I-thyroxine and fine structural alterations in the thyroid glands of Gunn rats fed polychlorinated biphenyls (PCB). Lab Invest (1980) 0.83

Persistent alterations in regional brain glial fibrillary acidic protein and synaptophysin levels following pre- and postnatal polychlorinated biphenyl exposure. Toxicol Appl Pharmacol (1996) 0.83

Teratogen update: polychlorinated biphenyls. Teratology (1997) 0.83

Effects of a polybrominated biphenyl mixture in the rat and mouse. I. Six-month exposure. Toxicol Appl Pharmacol (1983) 0.82

Developing forebrain astrocytes are sensitive to thyroid hormone. Glia (1990) 0.81

Comparative toxicity of polychlorinated biphenyl and polybrominated biphenylin the rat thyroid gland: light and electron microscopic alterations after subacute dietary exposure. J Environ Pathol Toxicol (1979) 0.81

Toxicity and disposition of 2,3,4,7,8-pentachlorodibenzofuran (4PeCDF) in the rhesus monkey (Macaca mulatta). Toxicol Appl Pharmacol (1988) 0.80

Effect of thyroxine on the development of somatosensory and visual evoked potentials in the rat. J Neurol Sci (1995) 0.80

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) effects on hepatic microsomal steroid metabolism and serum estradiol of pregnant rats. Biochem Pharmacol (1983) 0.79

Articles by these authors

(truncated to the top 100)

Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. Am J Epidemiol (1992) 8.82

A role for CD95 ligand in preventing graft rejection. Nature (1995) 6.07

Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer (2002) 5.83

Mortality, CD4 cell count decline, and depressive symptoms among HIV-seropositive women: longitudinal analysis from the HIV Epidemiology Research Study. JAMA (2001) 5.52

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding. J Virol (1995) 5.43

Lactation and a reduced risk of premenopausal breast cancer. N Engl J Med (1994) 5.37

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol (1996) 4.99

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia (2003) 4.17

Environmental exposure to polychlorinated biphenyls and quality of the home environment: effects on psychodevelopment in early childhood. Lancet (2001) 3.65

CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization. J Virol (1998) 3.60

Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop. Environ Health Perspect (1996) 3.34

Effectiveness of routine ultrasonography in detecting fetal structural abnormalities in a low risk population. BMJ (1991) 3.30

Pregnancy termination in relation to risk of breast cancer. JAMA (1996) 3.04

Direct detection of HIV RNA expression in seropositive subjects. Lancet (1988) 2.75

Use of the polymerase chain reaction for early detection of the proviral sequences of human immunodeficiency virus in infants born to seropositive mothers. New York City Collaborative Study of Maternal HIV Transmission and Montefiore Medical Center HIV Perinatal Transmission Study Group. N Engl J Med (1989) 2.73

Infectious complications of subcutaneous interleukin-2 and interferon-alpha. Lancet (1992) 2.65

Meta-analysis of epidemiologic dose-response data. Epidemiology (1993) 2.54

Molecular diagnosis of infective endocarditis--a new Duke's criterion. Scand J Infect Dis (2001) 2.36

Current status of ketamine anaesthesia. Lancet (1971) 2.28

Which gp160 vaccine? Nature (1993) 2.27

A semiparametric empirical likelihood method for data from an outcome-dependent sampling scheme with a continuous outcome. Biometrics (2002) 2.25

A new method for radionuclide imaging of myocardial infarcts. Radiology (1974) 2.24

Jewish religion and risk of breast cancer. Lancet (1996) 2.14

Certification, accreditation, and quality control in behavior analysis. Behav Anal (2001) 2.14

Lumbosacral cerebrospinal fluid volume is the primary determinant of sensory block extent and duration during spinal anesthesia. Anesthesiology (1998) 2.09

Oxybenzone oxidation following solar irradiation of skin: photoprotection versus antioxidant inactivation. J Invest Dermatol (1996) 2.07

Laryngeal mask airway for caesarean section. Anaesthesia (1990) 2.05

Human chromosome 12 is required for elevated HIV-1 expression in human-hamster hybrid cells. Science (1989) 2.03

Some historical and conceptual relations among logical positivism, operationism, and behaviorism. Behav Anal (1985) 1.99

Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos. Genes Dev (1992) 1.85

Head-upright tilt-table testing in evaluation and management of the malignant vasovagal syndrome. Am J Cardiol (1992) 1.82

Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer. Semin Oncol (1999) 1.82

Obesity and time to pregnancy. Hum Reprod (2006) 1.76

Stimulation of hepatic regeneration after partial hepatectomy by infusion of a cytosol extract from regenerating dog liver. Surg Gynecol Obstet (1980) 1.72

A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism. Teratology (1990) 1.72

A meta-analysis of body mass index and risk of premenopausal breast cancer. Epidemiology (1995) 1.70

Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-STO 22, to assess quality of life in patients with gastric cancer. Eur J Cancer (2004) 1.70

Parental consumption of contaminated sport fish from Lake Ontario and predicted fecundability. Epidemiology (2000) 1.69

A d.c. magnetic metamaterial. Nat Mater (2008) 1.69

Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study. Int Arch Occup Environ Health (1983) 1.69

Evaluation of midazolam as an intravenous induction agent. Anaesthesia (1981) 1.64

Body size and risk of breast cancer. Am J Epidemiol (1997) 1.63

Health services use by urban women with or at risk for HIV-1 infection: the HIV Epidemiology Research Study (HERS). J Acquir Immune Defic Syndr Hum Retrovirol (1998) 1.61

Long-term hormone replacement therapy and risk of breast cancer in postmenopausal women. Am J Epidemiol (1995) 1.59

General practitioners' and patients' models of obesity: whose problem is it? Patient Educ Couns (2001) 1.59

In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. J Investig Dermatol Symp Proc (1999) 1.58

Characterization of the ets oncogene family member, fli-1. J Biol Chem (1993) 1.57

Subsistence strategies of two "savanna" chimpanzee populations: the stable isotope evidence. Am J Primatol (1999) 1.57

A chink in HIV's armour? Nature (1990) 1.56

Ketamine as an induction agent in anaesthetics. Lancet (1970) 1.55

Cognitive and sensorimotor functions in 6-year-old children in relation to lead and mercury levels: adjustment for intelligence and contrast sensitivity in computerized testing. Neurotoxicol Teratol (1998) 1.54

Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants. Eur J Pharmacol (1995) 1.54

The role of ferritin and hemosiderin in the MR appearance of cerebral hemorrhage: a histopathologic biochemical study in rats. AJNR Am J Neuroradiol (1990) 1.53

Relation of vegetable, fruit, and grain consumption to colorectal adenomatous polyps. Am J Epidemiol (1996) 1.53

Colonic sulfide in pathogenesis and treatment of ulcerative colitis. Dig Dis Sci (1997) 1.52

Occupational exposure to 60-hertz magnetic fields and risk of breast cancer in women. Epidemiology (1996) 1.51

PCBs are a health risk for humans and wildlife. Science (2000) 1.51

BW373U86, a delta opioid agonist, partially mediates delayed cardioprotection via a free radical mechanism that is independent of opioid receptor stimulation. J Mol Cell Cardiol (2001) 1.51

Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1. Blood (1993) 1.50

Simultaneous retroperitoneal, thoracic, and cervical resection of postchemotherapy residual masses in patients with metastatic nonseminomatous germ cell tumors of the testis. J Clin Oncol (1996) 1.49

Choice and number of reinforcers. J Exp Anal Behav (1979) 1.49

Polychlorinated biphenyl serum concentrations, lifestyle and time-to-pregnancy. Hum Reprod (2008) 1.48

Non-cytocidal natural variants of human immunodeficiency virus isolated from AIDS patients with neurological disorders. Lancet (1987) 1.47

A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells. Ann Rheum Dis (2004) 1.46

Bioinformatics construction of the human cell surfaceome. Proc Natl Acad Sci U S A (2009) 1.45

Age at any full-term pregnancy and breast cancer risk. Am J Epidemiol (2000) 1.44

On privacy, causes, and contingencies. Behav Anal (1984) 1.42

Cesarean delivery in a patient with a transplanted heart. Anesthesiology (1989) 1.41

Women, violence, and HIV: a critical evaluation with implications for HIV services. Matern Child Health J (2000) 1.41

Second-harmonic tomography of tissues. Opt Lett (1997) 1.41

Effect of cold submersion on intramuscular temperature of the gastrocnemius muscle. Phys Ther (1979) 1.40

Paramedic field instructors: an approach to training the newest paramedics while maintaining the interest of the most successful senior paramedics. Prehosp Disaster Med (1995) 1.40

Critical care for the severely ill head and neck patient. Crit Care Med (1999) 1.40

Cost-efficient design of a diet validation study. Am J Epidemiol (1995) 1.39

Menstrual factors in relation to breast cancer risk. Cancer Epidemiol Biomarkers Prev (1998) 1.38

Direct demonstration of the human parvovirus in erythroid progenitor cells infected in vitro. J Clin Invest (1984) 1.38

Practice parameters for the management of colonic cancer I: surgical issues. Recommendations of the Colorectal Surgical Society of Australia. Aust N Z J Surg (1999) 1.38

Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates. Gene Ther (2006) 1.38

A clinical evaluation of the maternal effects of lumbar extradural analgesia for labour. Anaesthesia (1974) 1.37

Autologous hematopoietic stem cell transplantation for autoimmune diseases. Bone Marrow Transplant (2005) 1.37

DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer. Br J Cancer (2006) 1.36

Why do people seek treatment by alternative medicine? Br Med J (Clin Res Ed) (1985) 1.35

North and South Amerindians may have the same major founder Y chromosome haplotype. Am J Hum Genet (1996) 1.35

Effect of dose on the absorption and excretion of [14C]benzene administered orally or by inhalation in rats and mice. Toxicol Appl Pharmacol (1987) 1.34

Autism: recent molecular genetic advances. Hum Mol Genet (2000) 1.34

Rapid and quantitative detection of enzymatically amplified HIV-1 DNA using chemiluminescent oligonucleotide probes. AIDS Res Hum Retroviruses (1990) 1.33

The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo. Br J Cancer (2000) 1.33

Ectopic pregnancy. BMJ (2000) 1.32

Randomized, multicenter, open-label study of pegfilgrastim compared with daily filgrastim after chemotherapy for lymphoma. J Clin Oncol (2003) 1.32

Joint line restoration after revision total knee arthroplasty. Clin Orthop Relat Res (1999) 1.32

The New York Angler Cohort Study: exposure characterization and reproductive and developmental health. Toxicol Ind Health (1996) 1.31

Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo. Dev Dyn (1995) 1.30

Environmental organochlorine exposure and postmenopausal breast cancer risk. Cancer Epidemiol Biomarkers Prev (1998) 1.30

Acceptance of HIV testing during prenatal care. Perinatal Guidelines Evaluation Project. Public Health Rep (2001) 1.29

Immune-mediated thrombocytopenia of malaria. J Clin Invest (1983) 1.28

Evidence for a subsurface ocean on Europa. Nature (1998) 1.28

Mini-dose intrathecal morphine for the relief of post-cesarean section pain: safety, efficacy, and ventilatory responses to carbon dioxide. Anesth Analg (1988) 1.28

The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders. Proc Natl Acad Sci U S A (2000) 1.27

Auditory brainstem implant: II. Postsurgical issues and performance. Otolaryngol Head Neck Surg (1993) 1.27

Differences in the metabolism and disposition of inhaled [3H]benzene by F344/N rats and B6C3F1 mice. Toxicol Appl Pharmacol (1988) 1.27