Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma.

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Published in J Clin Oncol on September 01, 1999


P B Chapman1, L H Einhorn, M L Meyers, S Saxman, A N Destro, K S Panageas, C B Begg, S S Agarwala, L M Schuchter, M S Ernstoff, A N Houghton, J M Kirkwood

Author Affiliations

1: Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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High-dose cisplatin and dacarbazine in the treatment of metastatic melanoma. J Natl Cancer Inst (1990) 1.51

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Class 1 (unique) tumor antigens of human melanoma. Identification of a 90,000 dalton cell surface glycoprotein by autologous antibody. J Exp Med (1984) 1.48

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Metastatic patterns of choroidal melanoma. Cancer (1974) 1.45