Published in J Biol Chem on December 03, 1999
Resistance to Ralstonia solanacearum in Arabidopsis thaliana is conferred by the recessive RRS1-R gene, a member of a novel family of resistance genes. Proc Natl Acad Sci U S A (2002) 2.41
The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling. Plant Cell (2004) 2.05
Recruitment and interaction dynamics of plant penetration resistance components in a plasma membrane microdomain. Proc Natl Acad Sci U S A (2005) 2.05
Role of a heterotrimeric G protein in regulation of Arabidopsis seed germination. Plant Physiol (2002) 1.87
Heterotrimeric and unconventional GTP binding proteins in plant cell signaling. Plant Cell (2002) 1.84
The barley MLO modulator of defense and cell death is responsive to biotic and abiotic stress stimuli. Plant Physiol (2002) 1.80
Completing the heterotrimer: isolation and characterization of an Arabidopsis thaliana G protein gamma-subunit cDNA. Proc Natl Acad Sci U S A (2000) 1.69
Heterotrimeric G protein signalling in the plant kingdom. Open Biol (2013) 1.55
The plastid protein THYLAKOID FORMATION1 and the plasma membrane G-protein GPA1 interact in a novel sugar-signaling mechanism in Arabidopsis. Plant Cell (2006) 1.51
Barley MLO modulates actin-dependent and actin-independent antifungal defense pathways at the cell periphery. Plant Physiol (2007) 1.42
Conserved ERAD-like quality control of a plant polytopic membrane protein. Plant Cell (2004) 1.39
A rice spotted leaf gene, Spl7, encodes a heat stress transcription factor protein. Proc Natl Acad Sci U S A (2002) 1.35
A membrane protein/signaling protein interaction network for Arabidopsis version AMPv2. Front Physiol (2010) 1.30
GCR1, the putative Arabidopsis G protein-coupled receptor gene is cell cycle-regulated, and its overexpression abolishes seed dormancy and shortens time to flowering. Proc Natl Acad Sci U S A (2002) 1.30
Mining the Arabidopsis thaliana genome for highly-divergent seven transmembrane receptors. Genome Biol (2006) 1.26
Light-dependent death of maize lls1 cells is mediated by mature chloroplasts. Plant Physiol (2002) 1.20
A small GTP-binding host protein is required for entry of powdery mildew fungus into epidermal cells of barley. Plant Physiol (2002) 1.19
Overexpression of barley BAX inhibitor 1 induces breakdown of mlo-mediated penetration resistance to Blumeria graminis. Proc Natl Acad Sci U S A (2003) 1.15
Two seven-transmembrane domain MILDEW RESISTANCE LOCUS O proteins cofunction in Arabidopsis root thigmomorphogenesis. Plant Cell (2009) 1.11
PRGdb 2.0: towards a community-based database model for the analysis of R-genes in plants. Nucleic Acids Res (2012) 1.11
The Arabidopsis NHL3 gene encodes a plasma membrane protein and its overexpression correlates with increased resistance to Pseudomonas syringae pv. tomato DC3000. Plant Physiol (2003) 1.11
Subcellular localization and membrane topology of the melon ethylene receptor CmERS1. Plant Physiol (2006) 1.10
Reactive oxygen intermediates in plant-microbe interactions: who is who in powdery mildew resistance? Planta (2003) 1.08
Conserved extracellular cysteine residues and cytoplasmic loop-loop interplay are required for functionality of the heptahelical MLO protein. Biochem J (2005) 1.07
Novel induced mlo mutant alleles in combination with site-directed mutagenesis reveal functionally important domains in the heptahelical barley Mlo protein. BMC Plant Biol (2010) 1.02
Expression profiling and bioinformatic analyses of a novel stress-regulated multispanning transmembrane protein family from cereals and Arabidopsis. Plant Physiol (2003) 1.02
Comparative genomics of phylogenetically diverse unicellular eukaryotes provide new insights into the genetic basis for the evolution of the programmed cell death machinery. J Mol Evol (2009) 0.99
Blufensin1 negatively impacts basal defense in response to barley powdery mildew. Plant Physiol (2008) 0.97
Loss of function in Mlo orthologs reduces susceptibility of pepper and tomato to powdery mildew disease caused by Leveillula taurica. PLoS One (2013) 0.97
Quantitative Interactor Screening with next-generation Sequencing (QIS-Seq) identifies Arabidopsis thaliana MLO2 as a target of the Pseudomonas syringae type III effector HopZ2. BMC Genomics (2012) 0.94
Characterization of the MLO gene family in Rosaceae and gene expression analysis in Malus domestica. BMC Genomics (2014) 0.94
The role of Arabidopsis heterotrimeric G-protein subunits in MLO2 function and MAMP-triggered immunity. Mol Plant Microbe Interact (2013) 0.92
Plant disease susceptibility genes? Plant Cell (2002) 0.87
"Round up the usual suspects": a comment on nonexistent plant G protein-coupled receptors. Plant Physiol (2013) 0.85
Comparative phylogenetic analysis of genome-wide Mlo gene family members from Glycine max and Arabidopsis thaliana. Mol Genet Genomics (2014) 0.84
Induction of transcripts encoding a novel seven-transmembrane protein during the hypersensitive response to tobacco mosaic virus infection in tobacco plants. Planta (2003) 0.83
7TMRmine: a Web server for hierarchical mining of 7TMR proteins. BMC Genomics (2009) 0.83
Genetically based location from triploid populations and gene ontology of a 3.3-mb genome region linked to Alternaria brown spot resistance in citrus reveal clusters of resistance genes. PLoS One (2013) 0.83
Genome-Wide Study of the Tomato SlMLO Gene Family and Its Functional Characterization in Response to the Powdery Mildew Fungus Oidium neolycopersici. Front Plant Sci (2016) 0.83
Knockdown of MLO genes reduces susceptibility to powdery mildew in grapevine. Hortic Res (2016) 0.83
Isolation, Molecular Characterization, and Mapping of Four Rose MLO Orthologs. Front Plant Sci (2012) 0.82
A transposable element insertion in the susceptibility gene CsaMLO8 results in hypocotyl resistance to powdery mildew in cucumber. BMC Plant Biol (2015) 0.82
Comprehensive Phylogenetic Analysis Sheds Light on the Diversity and Origin of the MLO Family of Integral Membrane Proteins. Genome Biol Evol (2016) 0.81
Significant reduction of BiFC non-specific assembly facilitates in planta assessment of heterotrimeric G-protein interactors. Plant J (2014) 0.81
Sequence haplotypes revealed by sequence-tagged site fine mapping of the Ror1 gene in the centromeric region of barley chromosome 1H. Plant Physiol (2001) 0.81
Membrane topological structure of neutral system N/A amino acid transporter 4 (SNAT4) protein. J Biol Chem (2011) 0.80
Mining the Cicer arietinum genome for the mildew locus O (Mlo) gene family and comparative evolutionary analysis of the Mlo genes from Medicago truncatula and some other plant species. J Plant Res (2016) 0.80
OsMLO12, encoding seven transmembrane proteins, is involved with pollen hydration in rice. Plant Reprod (2014) 0.79
Mining, genetic mapping and expression analysis of EST-derived resistance gene homologs (RGHs) in cotton. BMC Plant Biol (2014) 0.79
Monocot and dicot MLO powdery mildew susceptibility factors are functionally conserved in spite of the evolution of class-specific molecular features. BMC Plant Biol (2015) 0.79
Distinct roles of the pepper pathogen-induced membrane protein gene CaPIMP1 in bacterial disease resistance and oomycete disease susceptibility. Planta (2008) 0.78
Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis. Mol Plant (2009) 0.77
Grapevine MLO candidates required for powdery mildew pathogenicity? Plant Signal Behav (2009) 0.76
Loss-of-Function Mutations in CsMLO1 Confer Durable Powdery Mildew Resistance in Cucumber (Cucumis sativus L.). Front Plant Sci (2015) 0.76
A Systematic View of the MLO Family in Rice Suggests Their Novel Roles in Morphological Development, Diurnal Responses, the Light-Signaling Pathway, and Various Stress Responses. Front Plant Sci (2016) 0.76
Arabidopsis research heats up in Seville. Plant Cell (2002) 0.76
Pepper mildew resistance locus O interacts with pepper calmodulin and suppresses Xanthomonas AvrBsT-triggered cell death and defense responses. Planta (2014) 0.75
Protein subcellular relocalization of duplicated genes in Arabidopsis. Genome Biol Evol (2014) 0.75
Functional characterization of cucumber (Cucumis sativus L.) Clade V MLO genes. BMC Plant Biol (2017) 0.75
Virus-induced gene silencing of the RPC5-like subunit of RNA polymerase III caused pleiotropic effects in Nicotiana benthamiana. Sci Rep (2016) 0.75
Comparative analysis of genome-wide Mlo gene family in Cajanus cajan and Phaseolus vulgaris. Genetica (2016) 0.75
Arabidopsis thaliana MLO genes are expressed in discrete domains during reproductive development. Plant Reprod (2017) 0.75
Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol (2001) 66.87
Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng (1997) 38.38
A new method for predicting signal sequence cleavage sites. Nucleic Acids Res (1986) 37.19
The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature (1997) 34.00
Patterns of amino acids near signal-sequence cleavage sites. Eur J Biochem (1983) 26.68
Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. J Mol Biol (2000) 22.77
Signal sequences. The limits of variation. J Mol Biol (1985) 21.24
A hidden Markov model for predicting transmembrane helices in protein sequences. Proc Int Conf Intell Syst Mol Biol (1998) 14.18
How signal sequences maintain cleavage specificity. J Mol Biol (1984) 11.03
TopPred II: an improved software for membrane protein structure predictions. Comput Appl Biosci (1994) 10.03
ChloroP, a neural network-based method for predicting chloroplast transit peptides and their cleavage sites. Protein Sci (1999) 9.82
Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. Protein Eng (1997) 8.25
Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms. Protein Sci (1998) 7.88
A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Int J Neural Syst (1999) 7.40
Mitochondrial targeting sequences may form amphiphilic helices. EMBO J (1986) 7.11
Machine learning approaches for the prediction of signal peptides and other protein sorting signals. Protein Eng (1999) 6.72
Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. Nature (1998) 5.91
Sequence determinants of cytosolic N-terminal protein processing. Eur J Biochem (1986) 5.59
The barley Mlo gene: a novel control element of plant pathogen resistance. Cell (1997) 4.55
A conserved cleavage-site motif in chloroplast transit peptides. FEBS Lett (1990) 4.25
Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering. Protein Eng (1990) 4.17
How proteins adapt to a membrane-water interface. Trends Biochem Sci (2000) 3.76
Trans-membrane translocation of proteins. The direct transfer model. Eur J Biochem (1979) 3.13
A contiguous 66-kb barley DNA sequence provides evidence for reversible genome expansion. Genome Res (2000) 3.10
Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane. J Biol Chem (1993) 3.02
The mlo resistance alleles to powdery mildew infection in barley trigger a developmentally controlled defence mimic phenotype. Mol Gen Genet (1993) 2.93
A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans. Cell (1999) 2.86
Predicting the topology of eukaryotic membrane proteins. Eur J Biochem (1993) 2.73
YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J (2000) 2.70
Rapid reorganization of resistance gene homologues in cereal genomes. Proc Natl Acad Sci U S A (1998) 2.53
Membrane proteins: the amino acid composition of membrane-penetrating segments. Eur J Biochem (1981) 2.52
Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells. EMBO J (1984) 2.43
Cleavage-site motifs in mitochondrial targeting peptides. Protein Eng (1990) 2.38
The Escherichia coli SRP and SecB targeting pathways converge at the translocon. EMBO J (1998) 2.35
A receptor component of the chloroplast protein translocation machinery. Science (1994) 2.34
Green fluorescent protein as an indicator to monitor membrane protein overexpression in Escherichia coli. FEBS Lett (2001) 2.28
Fine-tuning the topology of a polytopic membrane protein: role of positively and negatively charged amino acids. Cell (1990) 2.24
Inducible antibacterial defence system in Drosophila. Nature (1972) 2.08
A contiguous 60 kb genomic stretch from barley reveals molecular evidence for gene islands in a monocot genome. Nucleic Acids Res (1998) 2.06
On the hydrophobic nature of signal sequences. Eur J Biochem (1981) 2.01
Competition between Sec- and TAT-dependent protein translocation in Escherichia coli. EMBO J (1999) 1.95
The Mla (powdery mildew) resistance cluster is associated with three NBS-LRR gene families and suppressed recombination within a 240-kb DNA interval on chromosome 5S (1HS) of barley. Genetics (1999) 1.93
Prediction of organellar targeting signals. Biochim Biophys Acta (2001) 1.93
Structures of N-terminally acetylated proteins. Eur J Biochem (1985) 1.92
Assembly of a cytoplasmic membrane protein in Escherichia coli is dependent on the signal recognition particle. FEBS Lett (1996) 1.89
Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor. Mol Microbiol (1997) 1.85
Net N-C charge imbalance may be important for signal sequence function in bacteria. J Mol Biol (1986) 1.85
Functional borders, genetic fine structure, and distance requirements of cis elements mediating light responsiveness of the parsley chalcone synthase promoter. Proc Natl Acad Sci U S A (1990) 1.84
Topological rules for membrane protein assembly in eukaryotic cells. J Biol Chem (1997) 1.83
Amino acid distributions around O-linked glycosylation sites. Biochem J (1991) 1.82
Anionic phospholipids are determinants of membrane protein topology. EMBO J (1997) 1.77
The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistance specificity to Blumeria graminis f. sp. hordei in barley and wheat. Plant J (2001) 1.76
Molecular mechanism of membrane protein integration into the endoplasmic reticulum. Cell (1997) 1.70
Cell-autonomous expression of barley Mla1 confers race-specific resistance to the powdery mildew fungus via a Rar1-independent signaling pathway. Plant Cell (2001) 1.62
Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli. Proc Natl Acad Sci U S A (1998) 1.62
Topological "frustration" in multispanning E. coli inner membrane proteins. Cell (1994) 1.59
Degradation of phenol by Pseudomonas putida ATCC 11172 in continuous culture at different ratios of biofilm surface to culture volume. Appl Environ Microbiol (1985) 1.57
Consensus predictions of membrane protein topology. FEBS Lett (2000) 1.55
Membrane protein topology: effects of delta mu H+ on the translocation of charged residues explain the 'positive inside' rule. EMBO J (1994) 1.53
Structural analyses and dynamics of soluble and cell wall-bound phenolics in a broad spectrum resistance to the powdery mildew fungus in barley. J Biol Chem (1998) 1.53
Structural comparison, modes of expression, and putative cis-acting elements of the two 4-coumarate: CoA ligase genes in potato. J Biol Chem (1991) 1.52
Translation rate modification by preferential codon usage: intragenic position effects. J Theor Biol (1987) 1.51
A nascent secretory protein may traverse the ribosome/endoplasmic reticulum translocase complex as an extended chain. J Biol Chem (1996) 1.51
A parsley 4CL-1 promoter fragment specifies complex expression patterns in transgenic tobacco. Plant Cell (1991) 1.50
The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane. Biochemistry (1999) 1.49
Towards a comparative anatomy of N-terminal topogenic protein sequences. J Mol Biol (1986) 1.46
Chloroplast transit peptides from the green alga Chlamydomonas reinhardtii share features with both mitochondrial and higher plant chloroplast presequences. FEBS Lett (1990) 1.45
Axon diameter and myelin sheath thickness in nerve fibres of the ventral spinal root of the seventh lumbar nerve of the adult and developing cat. J Anat (1983) 1.44
A 30-residue-long "export initiation domain" adjacent to the signal sequence is critical for protein translocation across the inner membrane of Escherichia coli. Proc Natl Acad Sci U S A (1991) 1.43
The distribution of charged amino acids in mitochondrial inner-membrane proteins suggests different modes of membrane integration for nuclearly and mitochondrially encoded proteins. Eur J Biochem (1992) 1.42
Sec dependent and sec independent assembly of E. coli inner membrane proteins: the topological rules depend on chain length. EMBO J (1993) 1.41
Feature-extraction from endopeptidase cleavage sites in mitochondrial targeting peptides. Proteins (1998) 1.41
The 'positive-inside rule' applies to thylakoid membrane proteins. FEBS Lett (1991) 1.40
[Colitis--a partial phenomenon in adult Still disease?]. Lakartidningen (1993) 1.39
Apparent absence of Lyme borreliosis in Zimbabwe. Trans R Soc Trop Med Hyg (1995) 1.39
The COOH-terminal ends of internal signal and signal-anchor sequences are positioned differently in the ER translocase. J Cell Biol (1994) 1.39
Architecture of helix bundle membrane proteins: an analysis of cytochrome c oxidase from bovine mitochondria. Protein Sci (1997) 1.38
Determination of the border between the transmembrane and cytoplasmic domains of human integrin subunits. J Biol Chem (1999) 1.37
A turn propensity scale for transmembrane helices. J Mol Biol (1999) 1.37
Toxin production by Bacillus cereus dairy isolates in milk at low temperatures. Appl Environ Microbiol (1989) 1.37
Signal sequences are not uniformly hydrophobic. J Mol Biol (1982) 1.37
Expression of TGF-beta isoforms, TGF-beta receptors, and SMAD molecules at different stages of human glioma. Int J Cancer (2000) 1.36
Turns in transmembrane helices: determination of the minimal length of a "helical hairpin" and derivation of a fine-grained turn propensity scale. J Mol Biol (1999) 1.36
Life and death of a signal peptide. Nature (1998) 1.35
Regulators of cell death in disease resistance. Plant Mol Biol (2000) 1.34
Stop-transfer function of pseudo-random amino acid segments during translocation across prokaryotic and eukaryotic membranes. Eur J Biochem (1998) 1.34
Different conformations of nascent polypeptides during translocation across the ER membrane. BMC Cell Biol (2000) 1.34
Defining a similarity threshold for a functional protein sequence pattern: the signal peptide cleavage site. Proteins (1996) 1.31
Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix. J Mol Biol (1998) 1.27