Published in Blood on January 01, 2000
Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor. Blood (2010) 2.09
A mechanically stabilized receptor-ligand flex-bond important in the vasculature. Nature (2010) 1.90
Biology and physics of von Willebrand factor concatamers. J Thromb Haemost (2011) 1.33
von Willebrand factor, Jedi knight of the bloodstream. Blood (2014) 1.15
Limitations of the ristocetin cofactor assay in measurement of von Willebrand factor function. J Thromb Haemost (2009) 1.02
Structural basis of regulation of von Willebrand factor binding to glycoprotein Ib. J Biol Chem (2014) 0.97
Von Willebrand factor-A1 domain binds platelet glycoprotein Ibα in multiple states with distinctive force-dependent dissociation kinetics. Thromb Res (2015) 0.91
Misfolding of vWF to pathologically disordered conformations impacts the severity of von Willebrand disease. Biophys J (2014) 0.86
The unfolded von Willebrand factor response in bloodstream: the self-association perspective. J Hematol Oncol (2012) 0.81
Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα. Redox Biol (2015) 0.80
Ristocetin-induced self-aggregation of von Willebrand factor. Eur Biophys J (2010) 0.79
What a polyclonal antibody sees in von Willebrand factor. Thromb Res (2007) 0.79
Differential surface activation of the A1 domain of von Willebrand factor. Biointerphases (2016) 0.78
New Concepts and Mechanisms of Platelet Activation Signaling. Physiology (Bethesda) (2017) 0.75
The Von Willebrand Factor A1-Collagen III Interaction Is Independent of Conformation and Type 2 Von Willebrand Disease Phenotype. J Mol Biol (2016) 0.75
PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science (1990) 5.28
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem (2001) 4.81
Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor. J Thromb Haemost (2006) 4.58
Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function. Genome Res (2000) 3.55
Interactions between HIV and hepatitis B virus in homosexual men: effects on the natural history of infection. AIDS (1997) 2.88
Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18). J Exp Med (2000) 2.31
Bernard-Soulier syndrome. Blood (1998) 2.29
The glycoprotein Ib-IX-V complex is a platelet counterreceptor for P-selectin. J Exp Med (1999) 1.76
GMP-140 binding to neutrophils is inhibited by sulfated glycans. J Biol Chem (1991) 1.62
Protein structural alignments and functional genomics. Proteins (2001) 1.57
Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP140. Science (1990) 1.54
The vascular biology of the glycoprotein Ib-IX-V complex. Thromb Haemost (2001) 1.53
PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function. J Cell Sci (1999) 1.47
Molecular mechanisms of platelet adhesion and activation. Int J Biochem Cell Biol (1997) 1.46
Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci (2004) 1.46
Laboratory investigation of lupus anticoagulants: mixing studies are sometimes required. J Thromb Haemost (2010) 1.42
Dual antiplatelet therapy unmasks distinct platelet reactivity in patients with coronary artery disease. J Thromb Haemost (2008) 1.42
Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases. J Thromb Haemost (2007) 1.41
Purification and preliminary characterization of the glycoprotein Ib complex in the human platelet membrane. Eur J Biochem (1985) 1.40
Acquired von Willebrand disease: potential contribution of the VWF:CB to the identification of functionally inhibiting auto-antibodies to von Willebrand factor. J Thromb Haemost (2006) 1.40
Glycoprotein Ib-IX-V. Int J Biochem Cell Biol (2003) 1.38
Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors. Stem Cells (1998) 1.37
Identification of a novel integrin beta subunit expressed on cultured monocytes (macrophages). Evidence that one alpha subunit can associate with multiple beta subunits. J Biol Chem (1990) 1.36
Structure of the glycoprotein Ib.IX complex from platelet membranes. J Biol Chem (1988) 1.35
Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution. J Cell Biol (1992) 1.34
Regulation of in vitro capillary tube formation by anti-integrin antibodies. J Cell Biol (1993) 1.34
alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization. J Biol Chem (1995) 1.33
IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes. Genomics (1998) 1.31
P-selectin glycoprotein ligand-1 is the major counter-receptor for P-selectin on stimulated T cells and is widely distributed in non-functional form on many lymphocytic cells. J Biol Chem (1995) 1.29
Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model. J Cell Biol (1999) 1.29
Characterization of GMP-140 (P-selectin) as a circulating plasma protein. J Exp Med (1992) 1.28
Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils. Proc Natl Acad Sci U S A (1991) 1.28
Isolation of a repeated DNA sequence from Bordetella pertussis. J Gen Microbiol (1987) 1.28
Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling. Blood (2001) 1.28
PSGL-1-mediated adhesion of human hematopoietic progenitors to P-selectin results in suppression of hematopoiesis. Immunity (1999) 1.27
The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site. J Mol Biol (1997) 1.27
Identification of a membrane skeleton in platelets. J Cell Biol (1988) 1.25
The Met repressor-operator complex: DNA recognition by beta-strands. Ann N Y Acad Sci (1994) 1.25
Purification and preliminary physicochemical characterization of human platelet membrane glycoprotein V. J Biol Chem (1981) 1.24
Direct-to-consumer testing: more risks than opportunities. Int J Clin Pract (2011) 1.22
Binding of the von Willebrand factor A1 domain to histone. Thromb Res (1997) 1.21
Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. Biochemistry (1998) 1.21
A novel cobra venom metalloproteinase, mocarhagin, cleaves a 10-amino acid peptide from the mature N terminus of P-selectin glycoprotein ligand receptor, PSGL-1, and abolishes P-selectin binding. J Biol Chem (1995) 1.21
Binding of thrombin to glycoprotein Ib accelerates the hydrolysis of Par-1 on intact platelets. J Biol Chem (2000) 1.21
Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetra-span antigen, PETA-3. Blood (1995) 1.21
P-selectin directs T lymphocyte-mediated injury in delayed-type hypersensitivity responses: studies in glomerulonephritis and cutaneous delayed-type hypersensitivity. Eur J Immunol (1996) 1.19
Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex. Biochemistry (1989) 1.18
Chronic expression of P-selectin on endothelial cells stimulated by the T-cell cytokine, interleukin-3. Blood (1996) 1.17
Cleaved antitrypsin polymers at atomic resolution. Protein Sci (2000) 1.17
Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells. J Immunol (1994) 1.16
Plasma P-selectin is increased in thrombotic consumptive platelet disorders. Blood (1994) 1.16
A role for P selectin in complement-independent neutrophil-mediated glomerular injury. Kidney Int (1994) 1.16
The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin. J Cell Biol (2001) 1.15
P-selectin and platelet-activating factor mediate initial endotoxin-induced neutropenia. J Exp Med (1994) 1.14
Mild hemophilia A. J Thromb Haemost (2009) 1.13
The roles of ADP and TXA in botrocetin/VWF-induced aggregation of washed platelets. J Thromb Haemost (2004) 1.13
Urea and urease. Adv Inorg Biochem (1984) 1.13
Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane. Blood (1987) 1.13
Platelet GPIb-IX-V-dependent signaling. J Thromb Haemost (2005) 1.12
Expression and purification of recombinant human granzyme B from Pichia pastoris. Biochem Biophys Res Commun (1999) 1.12
Additional glycoprotein defects in Bernard-Soulier's syndrome: confirmation of genetic basis by parental analysis. Blood (1983) 1.11
Primitive human hematopoietic progenitors adhere to P-selectin (CD62P). Blood (1995) 1.11
Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta. Blood (2000) 1.11
Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival. Mol Cell (2000) 1.10
A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site. J Biol Chem (1992) 1.10
2B or not 2B? What is the role of VWF in platelet-matrix interactions? And what is the role of the VWF:CB in VWD diagnostics? These are the questions. J Thromb Haemost (2006) 1.08
Characterization of human platelet GMP-140 as a heparin-binding protein. Biochem Biophys Res Commun (1989) 1.07
The role of buffer anions and protons in secretion by the rabbit mandibular salivary gland. J Physiol (1982) 1.06
Activation of intragraft endothelial and mononuclear cells during discordant xenograft rejection. Transplantation (1994) 1.05
Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop. J Biol Chem (2001) 1.05
Activation of the 43 kDa inositol polyphosphate 5-phosphatase by 14-3-3zeta. Biochemistry (1997) 1.03
Characterization of a novel membrane glycoprotein involved in platelet activation. J Biol Chem (1989) 1.03
Association of a phospholipase A2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complex. J Biol Chem (1994) 1.02
von Willebrand factor mediates platelet spreading through glycoprotein Ib and alpha(IIb)beta3 in the presence of botrocetin and ristocetin, respectively. J Thromb Haemost (2006) 1.02
Mutagenesis of the dengue virus type 2 NS3 proteinase and the production of growth-restricted virus. J Gen Virol (2001) 1.02
Probing the unfolding pathway of alpha1-antitrypsin. J Biol Chem (1999) 1.02
A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen. Blood (1987) 1.01
Heparin-induced thrombocytopenia: mechanism of interaction of the heparin-dependent antibody with platelets. Br J Haematol (1989) 1.01
The glycoprotein Ib-IX-V complex in platelet adhesion and signaling. Thromb Haemost (1999) 1.01
Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity. Proc Natl Acad Sci U S A (2001) 1.00
Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. Blood (2001) 0.99
The structure and function of mammalian membrane-attack complex/perforin-like proteins. Tissue Antigens (2010) 0.98
Novel gain-of-function mutations of platelet glycoprotein IBalpha by valine mutagenesis in the Cys209-Cys248 disulfide loop. Functional analysis under statis and dynamic conditions. J Biol Chem (2000) 0.98