Published in J Epidemiol Community Health on December 01, 1999
Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med (1992) 14.22
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA (1995) 11.45
Possible prevention of neural-tube defects by periconceptional vitamin supplementation. Lancet (1980) 10.23
Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med (1996) 10.09
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med (1996) 8.57
Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA (1998) 7.09
Minimal compliance with the Department of Health recommendation for routine folate prophylaxis to prevent fetal neural tube defects. Br J Obstet Gynaecol (1994) 5.61
Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol (1969) 5.01
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation (1996) 4.62
Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men. JAMA (1996) 4.29
Disease gene mapping in isolated human populations: the example of Finland. J Med Genet (1993) 4.25
Double-blind randomised controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects. Br Med J (Clin Res Ed) (1981) 4.12
Therapeutic abortions with a folic acid antagonist, 4-aminopteroylglutamic acid (4-amino P.G.A) administered by the oral route. Am J Obstet Gynecol (1952) 4.05
A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA (1992) 3.96
Fruit and vegetables, and cardiovascular disease: a review. Int J Epidemiol (1997) 3.90
Coronary heart disease: seven dietary factors. Lancet (1991) 3.89
Homocysteine metabolism in pregnancies complicated by neural-tube defects. Lancet (1995) 3.70
Epidemiology of stillbirths and infant deaths due to congenital malformation. Lancet (1958) 3.15
Genetics of anencephaly. J Ment Defic Res (1957) 2.93
Serum folate and risk of fatal coronary heart disease. JAMA (1996) 2.58
Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest (1993) 2.47
Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet (1988) 2.35
The antioxidant vitamins and cardiovascular disease. A critical review of epidemiologic and clinical trial data. Ann Intern Med (1995) 2.32
THE ROLE OF FOLIC ACID IN PREGNANCY; WITH PARTICULAR REFERENCE TO ANAEMIA, ABRUPTION AND ABORTION. J Obstet Gynaecol Br Commonw (1964) 2.24
Ethnic differences in the prevalence of anencephaly and sina bifida in Boston, Massachusetts. N Engl J Med (1967) 2.24
Spina bifida and anencephaly: fewer patients, more problems. Br Med J (Clin Res Ed) (1983) 2.07
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation (1996) 2.06
A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects. QJM (1995) 2.05
American College of Cardiology 45th Annual Scientific Session, Orlando, Florida, March 24 to 27, 1996. Circulation (1996) 2.03
The distribution in England and Wales of mortality from coronary disease. Br Med J (1956) 1.88
Serum total homocysteine and coronary heart disease. Int J Epidemiol (1995) 1.79
Spina bifida and anencephaly in Scotland. Br Med J (Clin Res Ed) (1984) 1.75
Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci U S A (1994) 1.66
Methylenetetrahydrofolate reductase gene and coronary artery disease. Circulation (1997) 1.64
Incidence of congenital malformations in the regions of England and Wales. Br J Prev Soc Med (1970) 1.59
MTHFR 677C-->T mutation, folate intake, neural-tube defect, and risk of cardiovascular disease. Lancet (1997) 1.58
Anencephalus: variation with maternal age, parity, social class and region in England, Scotland and Wales. Ann Hum Genet (1970) 1.56
Nutritional ecogenetics: homocysteine-related arteriosclerotic vascular disease, neural tube defects, and folic acid. Am J Hum Genet (1996) 1.37
Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr (1993) 1.36
Sex and time trends in cardiovascular disease incidence and mortality: the Framingham Heart Study, 1950-1989. Am J Epidemiol (1996) 1.35
Prevention of neural tube defects. Lancet (1994) 1.31
Factors associated with anencephalus and spina bifida in Belfast. Br J Prev Soc Med (1973) 1.27
Congenital malformations and maternal occupation in Finland: multivariate analysis. J Epidemiol Community Health (1981) 1.23
Neural tube defects 1974-94--down but not out. Arch Dis Child Fetal Neonatal Ed (1996) 1.21
Nutritional patterns of mothers of children with neural tube defects in Newfoundland. Am J Med Genet (1995) 1.08
Hyperhomocysteinaemia: a metabolic risk factor for coronary heart disease determined by both genetic and environmental influences? Q J Med (1993) 1.05
Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation. Arterioscler Thromb Vasc Biol (1996) 1.00
Mortality due to coronary disease analyzed by broad occupational groups. AMA Arch Ind Health (1959) 1.00
The Chief Scientist reports.... Pattern of decline in prevalence of anencephaly and spina bifida in a high risk area. Health Bull (Edinb) (1992) 0.99
Heart attacks and homocysteine. BMJ (1996) 0.96
Coronary heart disease mortality trends in England and Wales, 1952-1991. J Public Health Med (1995) 0.92
Hyperhomocysteinaemia in stroke: prevalence, cause, and relationships to type of stroke and stroke risk factors. Eur J Clin Invest (1992) 0.92
Neural tube defects in New South Wales, Australia. J Med Genet (1978) 0.91
Folate and cardiovascular disease. Why we need a trial now. JAMA (1996) 0.79
The declining prevalence of anencephalus and spina bifida: its nature, causes and implications. Dev Med Child Neurol (1987) 0.79
Health inequalities among British civil servants: the Whitehall II study. Lancet (1991) 24.79
Misleading meta-analysis. BMJ (1995) 11.94
Why are the Japanese living longer? BMJ (1990) 8.54
Meta-Analysis. Potentials and promise. BMJ (1997) 8.06
Income inequality and mortality: importance to health of individual income, psychosocial environment, or material conditions. BMJ (2000) 8.02
Systematic reviews in health care: Investigating and dealing with publication and other biases in meta-analysis. BMJ (2001) 7.13
Meta-analysis: principles and procedures. BMJ (1997) 6.87
Deprivation in infancy or in adult life: which is more important for mortality risk? Lancet (1991) 6.84
Bias in location and selection of studies. BMJ (1998) 6.47
Second thoughts on the Jarman index. BMJ (1991) 5.99
Who benefits from medical interventions? BMJ (1994) 5.58
Social class differences in years of potential life lost: size, trends, and principal causes. BMJ (1990) 5.06
Systematic review of randomised controlled trials of multiple risk factor interventions for preventing coronary heart disease. BMJ (1997) 4.98
Association of cardiovascular disease risk factors with socioeconomic position during childhood and during adulthood. BMJ (1996) 4.88
Increasing inequalities in the health of the nation. BMJ (1994) 4.66
Income inequality, the psychosocial environment, and health: comparisons of wealthy nations. Lancet (2001) 4.48
Population requirement for primary hip-replacement surgery: a cross-sectional study. Lancet (1999) 4.29
Social capital--is it a good investment strategy for public health? J Epidemiol Community Health (2000) 4.25
Deprivation and mortality in Glasgow: changes from 1980 to 1992. BMJ (1994) 4.17
The independent inquiry into inequalities in health is welcome, but its recommendations are too cautious and vague. BMJ (1998) 3.97
Are we really dying for a tan? BMJ (1999) 3.74
Magnesium and myocardial infarction. Lancet (1994) 3.74
Weighting in the dark: resource allocation in the new NHS. BMJ (1993) 3.60
Height, leg length, and cancer risk: a systematic review. Epidemiol Rev (2001) 3.52
Birthweight, body-mass index in middle age, and incident coronary heart disease. Lancet (1996) 3.37
How independent are "independent" effects? Relative risk estimation when correlated exposures are measured imprecisely. J Clin Epidemiol (1991) 3.37
Dietary fat intake and prevention of cardiovascular disease: systematic review. BMJ (2001) 3.29
Milk, coronary heart disease and mortality. J Epidemiol Community Health (2001) 3.23
Mortality variations as a measure of general practitioner performance: implications of the Shipman case. BMJ (2000) 3.20
Deprivation and cause specific morbidity: evidence from the Somerset and Avon survey of health. BMJ (1996) 3.18
When does cardiovascular risk start? Past and present socioeconomic circumstances and risk factors in adulthood. J Epidemiol Community Health (1999) 3.15
Screening for chlamydial infections and the risk of ectopic pregnancy in a county in Sweden: ecological analysis. BMJ (1998) 3.12
Postal urine specimens: are they a feasible method for genital chlamydial infection screening? Br J Gen Pract (1999) 3.02
Cardiorespiratory disease in men and women in urban Scotland: baseline characteristics of the Renfrew/Paisley (midspan) study population. Scott Med J (1995) 2.99
Health effects of anticipation of job change and non-employment: longitudinal data from the Whitehall II study. BMJ (1995) 2.92
Lay epidemiology and the rationality of responses to health education. Br J Gen Pract (1991) 2.88
Adult height and mortality in London: early life, socioeconomic confounding, or shrinkage? J Epidemiol Community Health (1995) 2.71
Consensus conferences as drug promotion. Lancet (1993) 2.65
An uncertain future: the health effects of threats to employment security in white-collar men and women. Am J Public Health (1998) 2.57
Exporting failure? Coronary heart disease and stroke in developing countries. Int J Epidemiol (2001) 2.56
Income inequality and mortality: why are they related? BMJ (1996) 2.55
Income and health: what is the nature of the relationship? Soc Sci Med (1999) 2.51
Increasing the accessibility of data. BMJ (1994) 2.51
The ghost of Christmas past: health effects of poverty in London in 1896 and 1991. BMJ (2001) 2.49
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat Neurosci (2002) 2.43
Life course exposure and later disease: a follow-up study based on medical examinations carried out in Glasgow University (1948-68). Public Health (1999) 2.39
The limits of lifestyle: re-assessing 'fatalism' in the popular culture of illness prevention. Soc Sci Med (1992) 2.23
Magnitude and causes of mortality differences between married and unmarried men. J Epidemiol Community Health (1993) 2.17
Intergenerational 20 year trends in the prevalence of asthma and hay fever in adults: the Midspan family study surveys of parents and offspring. BMJ (2000) 2.13
Cloning and functional expression of a human orthologue of rat vanilloid receptor-1. Pain (2000) 2.11
Blood pressure in young adulthood and mortality from cardiovascular disease. Lancet (2000) 2.10
The design of prospective epidemiological studies: more subjects or better measurements? J Clin Epidemiol (1993) 2.08
People, places and coronary heart disease risk factors: a multilevel analysis of the Scottish Heart Health Study archive. Soc Sci Med (1997) 2.06
Birthweight, adult risk factors and incident coronary heart disease: the Caerphilly Study. Public Health (1996) 1.99
Birth dimensions of offspring, premature birth, and the mortality of mothers. Lancet (2000) 1.96
Birth weight and later socioeconomic disadvantage: evidence from the 1958 British cohort study. BMJ (1994) 1.93
Smoking and death. Public health measures were taken more than 40 years ago. BMJ (1995) 1.85
Childhood socioeconomic position and adult cardiovascular mortality: the Boyd Orr Cohort. Am J Epidemiol (1999) 1.84
The socioeconomic position of employed women, risk factors and mortality. Soc Sci Med (2001) 1.82
Blood pressure reactions to acute psychological stress and future blood pressure status: a 10-year follow-up of men in the Whitehall II study. Psychosom Med (2001) 1.80
Commentary: socioeconomic position should be measured accurately. BMJ (1999) 1.79
Social circumstances in childhood and cardiovascular disease mortality: prospective observational study of Glasgow University students. J Epidemiol Community Health (2001) 1.76
Transition-state stabilization and enzymic catalysis. Kinetic and molecular orbital studies of the rearrangement of chorismate to prephenate. Biochemistry (1973) 1.75
Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency. Lancet (2003) 1.74
Cardiovascular disease mortality in relation to childhood and adulthood socioeconomic markers in British South Asian men. Heart (2007) 1.73
When is mortality risk determined? Historical insights into a current debate. Soc Hist Med (1993) 1.72
Declaring independence: why we should be cautious. J Epidemiol Community Health (1990) 1.72
Socioeconomic differences in mortality in Britain and the United States. Am J Public Health (1992) 1.71
Risk factors for cardiorespiratory and all cause mortality in men and women in urban Scotland: 15 year follow up. Scott Med J (1995) 1.70
Bias in relative odds estimation owing to imprecise measurement of correlated exposures. Stat Med (1992) 1.70
Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer. Nature (1989) 1.69
Saltatory propagation of Ca2+ waves by Ca2+ sparks. Biophys J (1998) 1.68
Lowering blood pressure: a systematic review of sustained effects of non-pharmacological interventions. J Public Health Med (1998) 1.65
Job insecurity in white-collar workers: toward an explanation of associations with health. J Occup Health Psychol (2001) 1.65
Spark-to-wave transition: saltatory transmission of calcium waves in cardiac myocytes. Biophys Chem (1998) 1.63
Birth size and arterial compliance in young adults. Lancet (2000) 1.63
Chlamydia trachomatis detection and the menstrual cycle. Lancet (1998) 1.63
Prevention indicators for evaluating the progress of national AIDS programmes. AIDS (1994) 1.61
Cigarette smoking as a potential cause of cervical cancer: has confounding been controlled? Int J Epidemiol (1994) 1.61
Social mobility and 21 year mortality in a cohort of Scottish men. Soc Sci Med (1998) 1.61
Uses and abuses of meta-analysis. Clin Med (2002) 1.60
Mortality in Barrett's oesophagus: results from a population based study. Gut (2003) 1.60
Are women more sensitive to smoking than men? Findings from the Renfrew and Paisley study. Int J Epidemiol (2001) 1.59
Acne in adolescence and cause-specific mortality: lower coronary heart disease but higher prostate cancer mortality: the Glasgow Alumni Cohort Study. Am J Epidemiol (2005) 1.57
Observations of sexually transmitted disease consultations in India. Public Health (1998) 1.56
Anaerobic and aerobic hydrogen gas formation by the blue-green alga Anabaena cylindrica. Appl Environ Microbiol (1977) 1.55
Promotion of condom use in a high-risk setting in Nicaragua: a randomised controlled trial. Lancet (2000) 1.55
The effect of various dissolved gases on the heat defect of water. Med Phys (1985) 1.54
Frequency of somatic and germ-line mosaicism in retinoblastoma: implications for genetic counseling. Am J Hum Genet (1998) 1.54
Ecological study of social fragmentation, poverty, and suicide. BMJ (1999) 1.51
Homocysteine and coronary heart disease in the Caerphilly cohort: a 10 year follow up. Heart (2001) 1.49
Social capital, disorganized communities, and the third way: understanding the retreat from structural inequalities in epidemiology and public health. Int J Health Serv (2001) 1.48
Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist. Neuropharmacology (2004) 1.48
How accurately are height, weight and leg length reported by the elderly, and how closely are they related to measurements recorded in childhood? Int J Epidemiol (2000) 1.48
Leg length and risk of cancer in the Boyd Orr cohort. BMJ (1998) 1.47
Britain's first minister of public health. National centre for public health is needed. BMJ (1997) 1.46