Published in Virology on March 15, 2000
DNA vaccines to attack cancer. Proc Natl Acad Sci U S A (2004) 0.98
CD4(+) T cells induced by a DNA vaccine: immunological consequences of epitope-specific lysosomal targeting. J Virol (2001) 0.95
DNA vaccination can break immunological tolerance to PrP in wild-type mice and attenuates prion disease after intracerebral challenge. J Virol (2006) 0.88
Optimal induction of T-cell responses against hepatitis C virus E2 by antigen engineering in DNA immunization. J Virol (2003) 0.87
Expression library immunization can confer protection against lethal challenge with African swine fever virus. J Virol (2014) 0.85
Therapeutic vaccination of rabbits with a ubiquitin-fused papillomavirus E1, E2, E6 and E7 DNA vaccine. Vaccine (2007) 0.84
Enhancement of gp120-specific immune responses by genetic vaccination with the human immunodeficiency virus type 1 envelope gene fused to the gene coding for soluble CTLA4. J Virol (2003) 0.84
Vaccination strategies to enhance local immunity and protection against Mycobacteriun tuberculosis. Vaccine (2009) 0.83
Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases. Expert Rev Vaccines (2014) 0.78
The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini. Nucleic Acids Res (1985) 7.18
Fine dissection of a nine amino acid glycoprotein epitope, a major determinant recognized by lymphocytic choriomeningitis virus-specific class I-restricted H-2Db cytotoxic T lymphocytes. J Exp Med (1988) 4.75
CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge. J Virol (1996) 3.39
Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR. Nat Immunol (2001) 3.08
LCMV-specific, class II-restricted cytotoxic T cells in beta 2-microglobulin-deficient mice. Science (1992) 2.98
Replication origins and a sequence involved in coordinate induction of the immediate-early gene family are conserved in an intergenic region of herpes simplex virus. Nucleic Acids Res (1984) 2.35
Identification of Db- and Kb-restricted subdominant cytotoxic T-cell responses in lymphocytic choriomeningitis virus-infected mice. Virology (1998) 2.31
NK markers are expressed on a high percentage of virus-specific CD8+ and CD4+ T cells. J Immunol (2000) 2.15
Vaccination and protection from a lethal viral infection: identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope. Virology (1990) 2.12
Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection. J Virol (1989) 2.05
Immediate-early mRNA-2 of herpes simplex viruses types 1 and 2 is unspliced: conserved sequences around the 5' and 3' termini correspond to transcription regulatory signals. Nucleic Acids Res (1983) 2.01
Rapid on/off cycling of cytokine production by virus-specific CD8+ T cells. Nature (1999) 1.99
Activated and memory CD8+ T cells can be distinguished by their cytokine profiles and phenotypic markers. J Immunol (2000) 1.97
Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration. J Immunol (1998) 1.87
The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis. J Virol (1995) 1.83
DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection. J Virol (1995) 1.83
A modular system for the assay of transcription regulatory signals: the sequence TAATGARAT is required for herpes simplex virus immediate early gene activation. Nucleic Acids Res (1985) 1.75
DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction. J Virol (1997) 1.69
A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria. Proc Natl Acad Sci U S A (1999) 1.49
Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance. Am J Pathol (1998) 1.46
Vaccination to prevent persistent viral infection. J Virol (1993) 1.39
DNA immunization with minigenes: low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination. J Virol (1998) 1.34
Coxsackievirus infection of the pancreas: evaluation of receptor expression, pathogenesis, and immunopathology. Virology (2000) 1.32
DNA immunization. Trends Microbiol (1996) 1.26
The junctions between the repetitive and the short unique sequences of the herpes simplex virus genome are determined by the polypeptide-coding regions of two spliced immediate-early mRNAs. J Gen Virol (1984) 1.24
Antigen-specific regulation of T cell-mediated cytokine production. Immunity (2000) 1.24
Using recombinant coxsackievirus B3 to evaluate the induction and protective efficacy of CD8+ T cells during picornavirus infection. J Virol (2001) 1.20
DNA immunization to prevent autoimmune diabetes. J Clin Invest (1999) 1.20
An autologous oral DNA vaccine protects against murine melanoma. Proc Natl Acad Sci U S A (2000) 1.17
CTL escape viral variants. II. Biologic activity in vivo. Virology (1995) 1.15
A brief instrument for longitudinal monitoring of mood states. Psychiatry Res (1984) 1.13
Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization. J Virol (2000) 1.13
A common antiviral cytotoxic T-lymphocyte epitope for diverse major histocompatibility complex haplotypes: implications for vaccination. Proc Natl Acad Sci U S A (1992) 1.12
Enhancement of experimental allergic encephalomyelitis (EAE) by DNA immunization with myelin proteolipid protein (PLP) plasmid DNA. J Neuropathol Exp Neurol (1998) 1.11
Direct ex vivo kinetic and phenotypic analyses of CD8(+) T-cell responses induced by DNA immunization. J Virol (2000) 1.10
Two overlapping subdominant epitopes identified by DNA immunization induce protective CD8(+) T-cell populations with differing cytolytic activities. J Virol (2001) 1.06
Virus-induced diabetes in a transgenic model: role of cross-reacting viruses and quantitation of effector T cells needed to cause disease. J Virol (2000) 1.04
Exacerbation of viral and autoimmune animal models for multiple sclerosis by bacterial DNA. Brain Pathol (1999) 1.04
Clinical implications of dysregulated cytokine production. J Mol Med (Berl) (2000) 1.04
DNA immunization can stimulate florid local inflammation, and the antiviral immunity induced varies depending on injection site. Vaccine (1997) 1.03
Viruses can silently prime for and trigger central nervous system autoimmune disease. J Neurovirol (2001) 1.03
Ribozymes which cleave arenavirus RNAs: identification of susceptible target sites and inhibition by target site secondary structure. J Virol (1992) 1.03
Neonatal DNA immunization with a plasmid encoding an internal viral protein is effective in the presence of maternal antibodies and protects against subsequent viral challenge. J Virol (1997) 1.03
The role of B lymphocytes in coxsackievirus B3 infection. Am J Pathol (1999) 1.02
Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity. Gene Ther (2002) 1.01
Biometeorology. Can Med Assoc J (1985) 0.99
Polymorphism of cytotoxic T-lymphocyte clones that recognize a defined nine-amino-acid immunodominant domain of lymphocytic choriomeningitis virus glycoprotein. J Virol (1989) 0.98
CD4(+) T cells induced by a DNA vaccine: immunological consequences of epitope-specific lysosomal targeting. J Virol (2001) 0.95
Infradian rhythms. A comparison of affective disorders and normal persons. Arch Gen Psychiatry (1985) 0.95
Enhancement of autoimmune disease using recombinant vaccinia virus encoding myelin proteolipid protein. J Neuroimmunol (1993) 0.94
Quantitative and qualitative analyses of the immune responses induced by a multivalent minigene DNA vaccine. Vaccine (2000) 0.94
Preferential coxsackievirus replication in proliferating/activated cells: implications for virus tropism, persistence, and pathogenesis. Curr Top Microbiol Immunol (2008) 0.92
Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta. J Immunol (1994) 0.92
DNA immunization: effects of vehicle and route of administration on the induction of protective antiviral immunity. FEMS Immunol Med Microbiol (1996) 0.92
A recombinant minigene vaccine containing a nonameric cytotoxic-T-lymphocyte epitope confers limited protection against Listeria monocytogenes infection. Infect Immun (1996) 0.91
Protection of mice against lethal coxsackievirus B3 infection by using DNA immunization. J Virol (1998) 0.91
Weather and infradian rhythms in self-reports of health, sleep and mood measures. J Psychosom Res (1982) 0.90
Periodicities in self-reports of health, sleep and mood variables. J Psychosom Res (1978) 0.89
Limiting the available T cell receptor repertoire modifies acute lymphocytic choriomeningitis virus-induced immunopathology. J Neuroimmunol (1994) 0.87
Novel LCMV-specific H-2k restricted CTL clones recognize internal viral gene products and cause CNS disease. J Neuroimmunol (1992) 0.87
Vaccination protects beta 2 microglobulin deficient mice from immune mediated mortality but not from persisting viral infection. Vaccine (1996) 0.87
Plasmid DNA vaccines are effective in the absence of IFNgamma. Virology (1999) 0.87
Animal models using lymphocytic choriomeningitis virus. Curr Protoc Immunol (2001) 0.87
Effect of immune priming on Borna disease. J Virol (1999) 0.86
An anti-lymphocytic choriomeningitis virus ribozyme expressed in tissue culture cells diminishes viral RNA levels and leads to a reduction in infectious virus yield. J Virol (1993) 0.84
A rapid, inexpensive method for eluting DNA from agarose or acrylamide gel slices without using toxic or chaotropic materials. Biotechniques (1992) 0.84
Antisense-mediated resistance to measles virus infection in HeLa cells. J Infect Dis (1997) 0.82
Use of a high-affinity peptide that aborts MHC-restricted cytotoxic T lymphocyte activity against multiple viruses in vitro and virus-induced immunopathologic disease in vivo. Virology (1999) 0.82
Intravenous administration of human embryonic stem cell-derived neural precursor cells attenuates cuprizone-induced central nervous system (CNS) demyelination. Neuropathol Appl Neurobiol (2011) 0.82
Virus encoding an encephalitogenic peptide protects mice from experimental allergic encephalomyelitis. J Neuroimmunol (1996) 0.82
Infection with a recombinant vaccinia virus encoding myelin proteolipid protein causes suppression of chronic relapsing-remitting experimental allergic encephalomyelitis. J Neuroimmunol (1999) 0.81
Genetic dependence of the electroencephalogram bispectrum. Electroencephalogr Clin Neurophysiol (1985) 0.78
A rapid and simple method for determining the DNA sequences of fragments inserted into vaccinia virus. Biotechniques (1993) 0.78
The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes. Gene Ther (2003) 0.78
A spectral method for removing eye movement artifacts from the EEG. Electroencephalogr Clin Neurophysiol (1978) 0.78
Rapid accumulation of measles virus leader RNA in the nucleus of infected HeLa cells and human lymphoid cells. J Virol (1991) 0.78
DNA vaccination to treat autoimmune diabetes. Ann Med (2000) 0.77
EEG frequency patterns associated with hallucinations in schizophrenia and "creativity" in normals. Biol Psychiatry (1978) 0.77
Silver staining of nucleic acids. Applications in virus research and in diagnostic virology. J Virol Methods (1983) 0.77
Enhancing T cell activation and antiviral protection by introducing the HIV-1 protein transduction domain into a DNA vaccine. Hum Gene Ther (2001) 0.77
Induction of antiviral antibodies by DNA immunization requires neither perforin-mediated nor CD8(+)-T-cell-mediated lysis of antigen-expressing cells. J Virol (1999) 0.76
Use of a nonviral vector to express a chimeric tRNA-ribozyme against lymphocytic choriomeningitis virus: cytoplasmic accumulation of a catalytically competent transcript but minimal antiviral effect. Antisense Nucleic Acid Drug Dev (1997) 0.76
Multivalent minigene vaccines against infectious disease. Curr Opin Mol Ther (1999) 0.75
Antiviral activity of RNA molecules containing self-releasing ribozymes targeted to lymphocytic choriomeningitis virus. Antisense Res Dev (1995) 0.75
Enhancement of autoimmune disease using recombinant vaccinia virus encoding myelin proteolipid protein. J Neuroimmunol (1993) 0.75
Evoked potential maps in learning disabled children. Electroencephalogr Clin Neurophysiol (1986) 0.75