Published in EMBO J on April 17, 2000
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J Clin Invest (2002) 5.55
Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J Cell Biol (2002) 5.07
NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell (2008) 4.88
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest (2003) 4.58
A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol (2002) 3.09
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. Proc Natl Acad Sci U S A (2001) 2.91
TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation. EMBO J (2001) 2.81
Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro Oncol (2005) 2.74
Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease. J Med Genet (2005) 2.72
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J (2003) 2.67
Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control. Genes Dev (2002) 2.56
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program. Proc Natl Acad Sci U S A (2001) 2.55
Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells. Br J Cancer (2005) 2.37
TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev (2001) 2.35
Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro. Breast Cancer Res (2004) 2.33
Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA. Mol Biol Cell (2002) 2.27
Follistatin gene delivery enhances muscle growth and strength in nonhuman primates. Sci Transl Med (2009) 2.21
Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway. EMBO J (2003) 2.20
Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth. Cancer Res (2008) 2.19
Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res (2008) 2.18
Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury. Am J Pathol (2004) 2.17
A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers. Neoplasia (2005) 2.16
Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer. Genes Dev (2002) 2.13
Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling. J Biol (2005) 2.06
Obstructive nephropathy: insights from genetically engineered animals. Kidney Int (2005) 1.97
Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. Genes Dev (2001) 1.91
BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc Natl Acad Sci U S A (2009) 1.90
Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus. Mol Cell Biol (2000) 1.87
Arrestin development: emerging roles for beta-arrestins in developmental signaling pathways. Dev Cell (2009) 1.83
Re-employment of developmental transcription factors in adult heart disease. Semin Cell Dev Biol (2006) 1.82
High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo. Am J Physiol Cell Physiol (2009) 1.82
Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer. J Cell Physiol (2010) 1.81
Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element. Mol Cell Biol (2004) 1.77
Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis. Mol Biol Cell (2003) 1.73
Treble clef finger--a functionally diverse zinc-binding structural motif. Nucleic Acids Res (2001) 1.71
Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins. Mol Biol Cell (2001) 1.69
TGF-beta coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival. Exp Cell Res (2008) 1.69
Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation. Mol Cell Biol (2007) 1.68
Initial steps of metastasis: cell invasion and endothelial transmigration. Mutat Res (2011) 1.67
MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}. J Biol Chem (2010) 1.67
Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization. Mol Biol Cell (2005) 1.65
Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasion. Breast Cancer Res (2013) 1.64
Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling. Am J Pathol (2004) 1.61
Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta. EMBO J (2002) 1.59
Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner. Mol Biol Cell (2001) 1.58
Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes. J Cell Biol (2002) 1.58
Reactive oxygen species production via NADPH oxidase mediates TGF-beta-induced cytoskeletal alterations in endothelial cells. Am J Physiol Renal Physiol (2005) 1.58
In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis. Genes Dev (2004) 1.52
Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1. Mol Biol Cell (2001) 1.52
Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3. Mol Cell Biol (2003) 1.49
Structural basis for the inhibition of activin signalling by follistatin. EMBO J (2006) 1.49
RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation. J Biol Chem (2005) 1.48
Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia. EMBO J (2006) 1.47
Dual role of SnoN in mammalian tumorigenesis. Mol Cell Biol (2006) 1.47
Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF. EMBO J (2001) 1.47
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum. Proc Natl Acad Sci U S A (2007) 1.47
Retracted Gonadotropin releasing hormone analogue (GnRHa) alters the expression and activation of Smad in human endometrial epithelial and stromal cells. Reprod Biol Endocrinol (2003) 1.46
Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions. EMBO J (2003) 1.46
Prdm16 is required for normal palatogenesis in mice. Hum Mol Genet (2009) 1.46
A rapid and sensitive bioassay to measure bone morphogenetic protein activity. BMC Cell Biol (2007) 1.45
The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling. J Cell Biol (2001) 1.44
Amniotic Membrane Modifies the Genetic Program Induced by TGFß, Stimulating Keratinocyte Proliferation and Migration in Chronic Wounds. PLoS One (2015) 1.44
Role of transforming growth factor-beta in hematologic malignancies. Blood (2006) 1.41
Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells. Mol Cell Biol (2007) 1.41
TGIF inhibits retinoid signaling. Mol Cell Biol (2006) 1.40
CD133+ liver cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor (TGF)-beta-induced apoptosis. Hepatology (2009) 1.40
Transcriptional regulation of the Drosophila gene zen by competing Smad and Brinker inputs. Genes Dev (2001) 1.39
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. J Clin Invest (2009) 1.39
Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse. Am J Pathol (2001) 1.37
TGF-β/Smad signaling in renal fibrosis. Front Physiol (2015) 1.36
Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. Genes Dev (2005) 1.36
TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke. J Neuroinflammation (2010) 1.35
Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease. Muscle Nerve (2009) 1.34
Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT. Proc Natl Acad Sci U S A (2003) 1.34
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads. EMBO J (2001) 1.34
TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling. Nat Cell Biol (2010) 1.33
Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation. Mol Cell Biol (2004) 1.30
JAB1/CSN5: a new player in cell cycle control and cancer. Cell Div (2010) 1.29
Schistosoma mansoni TGF-beta receptor II: role in host ligand-induced regulation of a schistosome target gene. PLoS Pathog (2006) 1.29
Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3). Proc Natl Acad Sci U S A (2003) 1.29
Different effects of BMP-2 on marrow stromal cells from human and rat bone. Cells Tissues Organs (2004) 1.29
Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali. Am J Pathol (2005) 1.27
Prolonged mechanical ventilation with air induces apoptosis and causes failure of alveolar septation and angiogenesis in lungs of newborn mice. Am J Physiol Lung Cell Mol Physiol (2009) 1.27
RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells. Carcinogenesis (2007) 1.25
DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities. Proc Natl Acad Sci U S A (2002) 1.24
Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways. J Neuroinflammation (2010) 1.24
Anti-Müllerian hormone: an ovarian reserve marker in primary ovarian insufficiency. Nat Rev Endocrinol (2012) 1.24
The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling. Nucleic Acids Res (2000) 1.23
Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II. Mol Cell Biol (2007) 1.22
A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene. Mol Cell Biol (2005) 1.22
Glutathione suppresses TGF-beta-induced PAI-1 expression by inhibiting p38 and JNK MAPK and the binding of AP-1, SP-1, and Smad to the PAI-1 promoter. Am J Physiol Lung Cell Mol Physiol (2007) 1.22
Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance. Proc Natl Acad Sci U S A (2012) 1.21
Smad proteins regulate transcriptional induction of the SM22alpha gene by TGF-beta. Nucleic Acids Res (2003) 1.21
Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development. Mol Cell Biol (2001) 1.20
1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells. J Clin Endocrinol Metab (2011) 1.20
TGF-beta/Smad signaling defects in inflammatory bowel disease: mechanisms and possible novel therapies for chronic inflammation. J Clin Invest (2001) 1.20
Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk. Proc Natl Acad Sci U S A (2003) 1.20
A thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II. Am J Pathol (2007) 1.20
Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif. EMBO J (2002) 1.20
TGF-beta signal transduction. Annu Rev Biochem (1998) 17.83
TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature (1997) 15.75
Controlling TGF-beta signaling. Genes Dev (2000) 8.13
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. Nature (1997) 7.69
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science (1999) 7.51
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell (1997) 6.34
TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. Genes Dev (1990) 6.00
Human Smad3 and Smad4 are sequence-specific transcription activators. Mol Cell (1998) 5.88
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev (1996) 5.71
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response. Nat Cell Biol (1999) 5.58
Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature (1996) 5.21
A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras. Genes Dev (1999) 5.13
Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science (1999) 4.69
SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor. Cell (1998) 4.51
A human Mad protein acting as a BMP-regulated transcriptional activator. Nature (1996) 4.36
A transcriptional partner for MAD proteins in TGF-beta signalling. Nature (1996) 4.26
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature (1999) 4.17
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature (1998) 4.13
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. Cell (1998) 3.86
Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature (1997) 3.66
Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell (1999) 3.47
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2. Mol Cell (1998) 3.36
SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes. J Biol Chem (1999) 3.35
Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature (1997) 3.34
Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes. Genes Dev (1997) 3.33
A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature (1997) 3.29
Ubiquitin-dependent degradation of TGF-beta-activated smad2. Nat Cell Biol (1999) 3.25
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer. J Biol Chem (1998) 3.23
Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature (1999) 3.16
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Genes Dev (1998) 3.16
OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell (2000) 3.12
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature (1997) 3.12
A Smad transcriptional corepressor. Cell (1999) 3.07
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J (1999) 3.05
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation. Genes Dev (1998) 2.82
Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart. Science (1999) 2.72
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes Dev (1999) 2.52
New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites. EMBO J (1999) 2.47
Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter. J Biol Chem (1999) 2.44
TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300. Genes Dev (1998) 2.40
Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression. J Biol Chem (1999) 2.40
A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J Biol Chem (1995) 2.40
c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads. J Biol Chem (1999) 2.32
Cooperative binding of Ets-1 and core binding factor to DNA. Mol Cell Biol (1994) 2.27
Determinants of specificity in TGF-beta signal transduction. Genes Dev (1998) 2.23
Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors. EMBO J (1998) 2.20
The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3. Nature (1998) 2.18
Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif. Genes Dev (2000) 2.13
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta. Mol Cell Biol (1999) 2.08
Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker. Cell (1999) 2.07
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling. Proc Natl Acad Sci U S A (1999) 2.06
Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4. Mol Cell Biol (1997) 2.05
Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling. Mol Cell (1999) 1.91
Characterization of human FAST-1, a TGF beta and activin signal transducer. Mol Cell (1998) 1.90
Regulation of Smad7 promoter by direct association with Smad3 and Smad4. J Biol Chem (1999) 1.88
Regulation of Smad signalling by protein associations and signalling crosstalk. Trends Cell Biol (1999) 1.87
Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo. Proc Natl Acad Sci U S A (1993) 1.85
ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling. J Biol Chem (1999) 1.83
The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation. Cell (1999) 1.81
Smads bind directly to the Jun family of AP-1 transcription factors. Proc Natl Acad Sci U S A (1999) 1.81
Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol Cell (2000) 1.78
Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. Genes Dev (1998) 1.77
Physical and functional interaction of SMADs and p300/CBP. J Biol Chem (1998) 1.77
Identification of DNA recognition sequences and protein interaction domains of the multiple-Zn-finger protein Roaz. Mol Cell Biol (1998) 1.75
Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors. J Biol Chem (1999) 1.71
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain. J Biol Chem (2000) 1.70
TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein. Mol Biol Cell (1998) 1.67
Structural basis of Smad2 recognition by the Smad anchor for receptor activation. Science (2000) 1.66
A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity. EMBO J (1997) 1.65
Multiple modes of repression by the Smad transcriptional corepressor TGIF. J Biol Chem (1999) 1.61
Smad1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling. J Biol Chem (1999) 1.56
The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors. EMBO J (1998) 1.54
A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. EMBO J (1997) 1.52
Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation. J Biol Chem (1999) 1.47
brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes. Nature (1999) 1.47
Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator. Proc Natl Acad Sci U S A (1998) 1.41
Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals. Proc Natl Acad Sci U S A (1993) 1.32
Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins. Proc Natl Acad Sci U S A (1999) 1.30
Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements. J Immunol (1992) 1.29
FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo. Development (1999) 1.27
Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes. J Biol Chem (2000) 1.23
Identification of two Smad4 proteins in Xenopus. Their common and distinct properties. J Biol Chem (1999) 1.19
Interaction of Smad complexes with tripartite DNA-binding sites. J Biol Chem (1999) 1.17
The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis. J Biol Chem (1999) 1.17
Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-beta. J Biol Chem (1998) 1.15
Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes. Dev Biol (1999) 1.09
Retracted Positive and negative modulation of vitamin D receptor function by transforming growth factor-beta signaling through smad proteins. J Biol Chem (1999) 1.03
Transcriptional activation by ETS and leucine zipper-containing basic helix-loop-helix proteins. Mol Cell Biol (1999) 0.96
Runt domains take the lead in hematopoiesis and osteogenesis. Nat Med (1999) 0.95
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature (1997) 3.12
Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination. Nat Genet (2000) 2.53
Determinants of specificity in TGF-beta signal transduction. Genes Dev (1998) 2.23
The structure of the human CD2 gene and its expression in transgenic mice. EMBO J (1988) 2.00
The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF. J Biol Chem (2000) 1.49
Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF. EMBO J (2001) 1.47
A phorbol ester response element within the human T-cell receptor beta-chain enhancer. Proc Natl Acad Sci U S A (1992) 1.44
TGIF2 interacts with histone deacetylase 1 and represses transcription. J Biol Chem (2001) 1.38
A 3' transcriptional enhancer regulates tissue-specific expression of the human CD2 gene. EMBO J (1990) 1.14
Rap1p and telomere length regulation in yeast. Ciba Found Symp (1997) 1.09
Identification and functional analysis of the transcriptional enhancer of the human T cell receptor beta gene. Eur J Immunol (1991) 0.89
DNase hypersensitivity and methylation of the human CD3G and D genes during T-cell development. Immunogenetics (1990) 0.77
Analysis of CD2 and TCR-beta gene expression in Jurkat cell mutants suggests a cis regulation of gene transcription. J Immunol (1995) 0.75
ACTION: application and extension of the GENESIS community analysis model. Public Health Nurs (1996) 0.75