Published in Nature on May 29, 1975
Induction of plasminogen activator synthesis by antibodies. J Exp Med (1981) 0.81
Humoral immunostimulation. V. Selection of variant cell lines. J Exp Med (1975) 0.75
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group. N Engl J Med (1991) 9.99
Radioimmunoassay for cyclic nucleotides. I. Preparation of antibodies and iodinated cyclic nucleotides. J Biol Chem (1972) 8.24
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Human lymphocytic metabolism. Effects of cyclic and noncyclic nucleotides on stimulation by phytohemagglutinin. J Clin Invest (1971) 3.01
Cyclic adenosine 3',5'-monophosphate in human lymphocytes. Alterations after phytohemagglutinin stimulation. J Clin Invest (1971) 2.61
Alterations in cyclic adenosine monophosphate metabolism in human bronchial asthma. I. Leukocyte responsiveness to -adrenergic agents. J Clin Invest (1973) 2.42
Are low tidal volumes safe? Chest (1990) 2.26
The measurement of digitoxin in human serum by radioimmunoassay. J Clin Invest (1968) 2.16
Reactions following intravenous fluorescein. Am J Ophthalmol (1971) 2.13
Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats. Crit Care Med (2001) 2.12
Radioimmunoassay measurement of prostaglandins E, A, and F in human plasma. J Clin Invest (1973) 2.09
Modulation of cyclic AMP in purified rat mast cells. I. Responses to pharmacologic, metabolic, and physical stimuli. J Immunol (1975) 2.07
Potentiation of mast cell mediator release by adenosine. J Immunol (1978) 2.05
A multicenter, randomized, double-blind, placebo-controlled trial of high-dose intravenous immunoglobulin for oral corticosteroid-dependent asthma. Clin Immunol (1999) 2.04
Tissue capnometry as a monitoring strategy for critically ill patients: just about ready for prime time. Chest (1998) 2.04
Radioimmunoassay for prostaglandins. Science (1971) 1.99
Gastric tonometry and venous oximetry in cardiac surgery patients. Crit Care Med (1991) 1.94
Cytokinin Biochemistry in Relation to Leaf Senescence: IV. Cytokinin Metabolism in Soybean Explants. Plant Physiol (1988) 1.87
Precursor role of arachidonic acid in release of slow reacting substance from rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1977) 1.86
Quantitation of cytokinins in biological samples using antibodies against zeatin riboside. Plant Physiol (1984) 1.84
Cytokine-induced intestinal epithelial hyperpermeability: role of nitric oxide. Crit Care Med (1999) 1.81
Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids. J Clin Invest (1979) 1.77
Lymphocyte activation. Prog Allergy (1976) 1.69
Acidic conditions exacerbate interferon-gamma-induced intestinal epithelial hyperpermeability: role of peroxynitrous acid. Crit Care Med (1999) 1.69
Prostaglandins, macrophages, and immunity. J Immunol (1980) 1.69
Inhibition of inducible nitric oxide synthase ameliorates endotoxin-induced gut mucosal barrier dysfunction in rats. Gastroenterology (1997) 1.67
Preparation and characterization, using high-performance liquid chromatography, of an enzyme forming glucosides of cytokinins. Biochim Biophys Acta (1979) 1.61
Hormonal responses to graded surgical stress. Arch Intern Med (1987) 1.59
Release of slow reacting substance (SRS) from rat basophilic leukemia (RBL-1) cells. J Immunol (1977) 1.58
Isolation of pure human peripheral blood T-lymphocytes using nylon wool columns. Immunol Commun (1972) 1.58
Morphine: radioimmunoassay. Science (1970) 1.56
Monohydroxyeicosatetraenoic acids (HETEs) induce degranulation of human neutrophils. J Immunol (1980) 1.55
Activation of phospholipid metabolism during mediator release from stimulated rat mast cells. J Immunol (1979) 1.54
Modulation of cyclic AMP in purified rat mast cells. II. Studies on the relationship between intracellular cyclic AMP concentrations and histamine release. J Immunol (1975) 1.52
Desensitization of patients allergic to penicillin using orally administered beta-lactam antibiotics. J Allergy Clin Immunol (1982) 1.48
Use of ultrahigh frequency ventilation in patients with ARDS. A preliminary report. Chest (1993) 1.45
Urinary retention in a neonate secondary to maternal ingestion of nortriptyline. J Pediatr (1972) 1.41
Safety of the maternal-infant zidovudine regimen utilized in the Pediatric AIDS Clinical Trial Group 076 Study. AIDS (1998) 1.40
Nitric oxide donors increase cytosolic ionized calcium in cultured human intestinal epithelial cells. Shock (1996) 1.40
CT grading of splenic trauma in adults: how the same statistics can be interpreted differently. Radiology (1991) 1.39
Skin testing to detect penicillin allergy. J Allergy Clin Immunol (1981) 1.37
Another negative clinical trial of a new agent for the treatment of sepsis: rethinking the process of developing adjuvant treatments for serious infections. Crit Care Med (1995) 1.37
Secondary infection of post-traumatic pulmonary cavitary lesions in adolescents and young adults: role of computed tomography and operative debridement and drainage. J Trauma (1989) 1.37
Drug therapy. During allergy (third of three parts). N Engl J Med (1975) 1.36
Opportunistic infection in children. II. In the compromised host. J Pediatr (1975) 1.36
Regulators of cell division in plant tissue. XXIII. The identity of an unusual metabolite of 6-benzylaminopurine. Biochim Biophys Acta (1975) 1.36
Gram-negative bacteremia produces both severe systolic and diastolic cardiac dysfunction in a canine model that simulates human septic shock. J Clin Invest (1986) 1.34
Epstein-Barr virus-associated B-cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency. N Engl J Med (1985) 1.32
Excess intrauterine fetal demise associated with maternal human immunodeficiency virus infection. J Infect Dis (1995) 1.30
Radioimmunoassay for the measurement of cyclic nucleotides. Adv Cyclic Nucleotide Res (1972) 1.29
Left ventricular systolic and diastolic dysfunction after infusion of tumor necrosis factor-alpha in conscious dogs. J Clin Invest (1992) 1.29
Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. J Immunol (1979) 1.28
Modulation of cyclic AMP in purified rat mast cells. III. Studies on the effects of concanavalin A and anti-IgE on cyclic AMP concentrations during histamine release. J Immunol (1976) 1.26
Endotoxemia causes ileal mucosal acidosis in the absence of mucosal hypoxia in a normodynamic porcine model of septic shock. Crit Care Med (1995) 1.26
Improved radioimaging and tumor localization with monoclonal F(ab')2. J Nucl Med (1983) 1.26
Nitric oxide dilates tight junctions and depletes ATP in cultured Caco-2BBe intestinal epithelial monolayers. Am J Physiol (1995) 1.25
Raphanatin, an unusual purine derivative and a metabolite of zeatin. Biochem Biophys Res Commun (1972) 1.24
Possible role of arachidonic acid and its metabolites in mediator release from rat mast cells. J Immunol (1979) 1.23
Stickler syndrome in a pedigree of Pierre Robin syndrome. Am J Dis Child (1973) 1.22
EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine. J Pharmacol Exp Ther (1995) 1.21
Fluorescent probes for the study of the antibody-hapten reaction. I. Binding of the 5-dimethylaminonaphthalene-1-sulfonamido group by homologous rabbit antibody. Biochemistry (1967) 1.20
Clonal analysis of transplant-associated lymphoproliferations based on the structure of the genomic termini of the Epstein-Barr virus. Blood (1988) 1.19
The preparation of nucleotide-protein conjugates: carbodiimides as coupling agents. J Immunol (1966) 1.18
Nonoperative treatment of adult splenic trauma: development of a computed tomographic scoring system that detects appropriate candidates for expectant management. J Trauma (1988) 1.18
Specific binding of leukotriene B4 to a receptor on human polymorphonuclear leukocytes. J Exp Med (1983) 1.17
Effect of mesenteric ischemia and reperfusion or hemorrhagic shock on intestinal mucosal permeability and ATP content in rats. Shock (1999) 1.17
Correlation between mitogenicity and stimulation of calcium uptake in human lymphocytes. Biochem Biophys Res Commun (1974) 1.15
Concanavalin A-induced histamine release from normal rat mast cells. J Immunol (1975) 1.15
Reversible disruption by cupric ions of a helical conformation of a polypeptide derived from ribonuclease. J Biol Chem (1966) 1.13
A comparative study of the immunohistochemical localization of basic protein to myelin and oligodendrocytes in rat and chicken brain. J Comp Neurol (1979) 1.13
-Globulin binding of morphine in heroin addicts. J Lab Clin Med (1972) 1.13
Detection of Australia antigen by radioimmunoassay. Proc Natl Acad Sci U S A (1971) 1.13
Sites of binding of copper (II) ion by peptide (1-24) of bovine serum albumin. J Biol Chem (1968) 1.12
A method for detecting intracellular cyclic adenosine monophosphate by immunofluorescence. J Histochem Cytochem (1972) 1.12
Immunochemical studies with lysine vasopressin. Endocrinology (1966) 1.12
The effect of Bordetella pertussis on lymphocyte cyclic AMP metabolism. J Exp Med (1973) 1.12
Alterations in cyclic AMP metabolism in human bronchial asthma. 3. Leukocyte and lymphocyte responses to steroids. J Clin Invest (1973) 1.12
Selective cytotoxicity of hapten-substituted cells with an antibody-enzyme conjugate. J Immunol (1973) 1.11
Diacylglycerol metabolism in mast cells: a potential role in membrane fusion and arachidonic acid release. J Exp Med (1979) 1.10
The rat basophilic leukemia cell receptor for IgE. I. Characterization as a glycoprotein. J Immunol (1976) 1.10
Hydrophobic binding sites on immunoglobulins. Biochemistry (1970) 1.10
Validation of tonometric measurement of gut intramural pH during endotoxemia and mesenteric occlusion in pigs. Am J Physiol (1990) 1.09
Interpreting dual-sugar absorption studies in critically ill patients: what are the implications of apparent increases in intestinal permeability to hydrophilic solutes? Intensive Care Med (1997) 1.09
Norepinephrine alone versus norepinephrine plus low-dose dopamine: enhanced renal blood flow with combination pressor therapy. Crit Care Med (1985) 1.08
The use of protein-substituted nylon catheters for selective immunoadsorption in vivo. J Immunol (1974) 1.08
Inflammatory cytokine expression is correlated with the level of human immunodeficiency virus (HIV) transcripts in HIV-infected placental trophoblastic cells. J Virol (1997) 1.08
Synthesis of DNA and poly(adenosine diphosphate ribose) in normal and chronic lymphocytic leukemia lymphocytes. J Clin Invest (1978) 1.07
12-L-hydroxy-5,8,10,14-eicosatetraenoic acid, a chemotactic fatty acid, is incorporated into neutrophil phospholipids and triglyceride. Prostaglandins (1979) 1.07
Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal. J Biol Chem (1976) 1.07
Prostaglandins and slow-reacting substance. J Allergy Clin Immunol (1979) 1.07
Cyclic AMP and the immune response;. Adv Cyclic Nucleotide Res (1974) 1.07
Comparison of CD8(+) T-cell subsets in HIV-infected rapid progressor children versus non--rapid progressor children. J Allergy Clin Immunol (2001) 1.06
Sequential conversion of the glutathionyl side chain of slow reacting substance (SRS) to cysteinyl-glycine and cysteine in rat basophilic leukemia cells stimulated with A-23187. Prostaglandins (1980) 1.06
Effect of serotonin on murine macrophages: suppression of Ia expression by serotonin and its reversal by 5-HT2 serotonergic receptor antagonists. J Immunol (1986) 1.06