Published in Biochim Biophys Acta on December 10, 1999
Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs. Nucleic Acids Res (2001) 1.67
Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons. Nucleic Acids Res (2008) 1.44
Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets. Nucleic Acids Res (2002) 1.26
2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides (2'F-ANA): synthesis and physicochemical studies. Nucleic Acids Res (2000) 1.23
NMR structure of an alpha-L-LNA:RNA hybrid: structural implications for RNase H recognition. Nucleic Acids Res (2003) 1.06
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. Biochemistry (2006) 1.00
Synthesis and physical and physiological properties of 4'-thioRNA: application to post-modification of RNA aptamer toward NF-kappaB. Nucleic Acids Res (2004) 1.00
Therapeutic Opportunities for Targeting microRNAs in Cancer. Mol Cell Ther (2014) 0.94
Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex. Cell Cycle (2008) 0.92
Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules. Nucleic Acids Res (2004) 0.91
Antisense properties of tricyclo-DNA. Nucleic Acids Res (2002) 0.90
Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids. Nucleic Acids Res (2001) 0.88
Inhibition of pre-mRNA splicing by synthetic branched nucleic acids. Nucleic Acids Res (2003) 0.87
The crystal structure of an 'All Locked' nucleic acid duplex. Nucleic Acids Res (2010) 0.87
Crystallographic studies of chemically modified nucleic acids: a backward glance. Chem Biodivers (2010) 0.86
Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines. Nucleic Acids Res (2005) 0.86
Effective exon skipping and dystrophin restoration by 2'-o-methoxyethyl antisense oligonucleotide in dystrophin-deficient mice. PLoS One (2013) 0.86
Crystallization and preliminary X-ray analysis of Escherichia coli RNase HI-dsRNA complexes. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.84
A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution. Chem Commun (Camb) (2009) 0.84
Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic. Front Chem (2014) 0.84
Hybridization of 2'-ribose modified mixed-sequence oligonucleotides: thermodynamic and kinetic studies. Nucleic Acids Res (2001) 0.84
Oligonucleotide-based tools for studying zebrafish development. Zebrafish (2010) 0.84
Exon-skipping antisense oligonucleotides to correct missplicing in neurogenetic diseases. Nucleic Acid Ther (2014) 0.83
2'-O-[2-[(N,N-dimethylamino)oxy]ethyl]-modified oligonucleotides inhibit expression of mRNA in vitro and in vivo. Nucleic Acids Res (2004) 0.82
Synthesis and characterization of 2'-modified-4'-thioRNA: a comprehensive comparison of nuclease stability. Nucleic Acids Res (2009) 0.82
The conformationally constrained N-methanocarba-dT analogue adopts an unexpected C4'-exo sugar pucker in the structure of a DNA hairpin. Biochemistry (2012) 0.81
Use of fully modified 2'-O-methyl antisense oligos for loss-of-function studies in vertebrate embryos. Genesis (2011) 0.81
Tuning of conformational preorganization in model 2',5'- and 3',5'-linked oligonucleotides by 3'- and 2'-O-methoxyethyl modification. Nucleic Acids Res (2003) 0.80
A novel concept for ligand attachment to oligonucleotides via a 2'-succinyl linker. Nucleic Acids Res (2004) 0.79
Optimizations of siRNA design for the activation of gene transcription by targeting the TATA-box motif. PLoS One (2014) 0.78
The chemical evolution of oligonucleotide therapies of clinical utility. Nat Biotechnol (2017) 0.77
2'-O-hydroxyalkoxymethylribonucleosides and their incorporation into oligoribonucleotides. Nucleosides Nucleotides Nucleic Acids (2007) 0.77
Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice. Mol Ther Nucleic Acids (2016) 0.76
Structure/affinity studies in the bicyclo-DNA series: Synthesis and properties of oligonucleotides containing bc(en)-T and iso-tricyclo-T nucleosides. Beilstein J Org Chem (2014) 0.76
Multipyrene tandem probes for point mutations detection in DNA. J Nucleic Acids (2013) 0.75
A novel dual lock method for down-regulation of genes, in which a target mRNA is captured at 2 independent positions by linked locked nucleic acid antisense oligonucleotides. RNA Biol (2016) 0.75
Solid-phase synthesis and hybrization behavior of partially 2'/3'-O-acetylated RNA oligonucleotides. J Org Chem (2014) 0.75
Features of "All LNA" Duplexes Showing a New Type of Nucleic Acid Geometry. J Nucleic Acids (2012) 0.75
Oligonucleotide transition state analogues of saporin L3. Eur J Med Chem (2016) 0.75
Permanent or reversible conjugation of 2'-O- or 5'-O-aminooxymethylated nucleosides with functional groups as a convenient and efficient approach to the modification of RNA and DNA sequences. Nucleic Acids Res (2011) 0.75