Published in Leukemia on August 01, 2000
Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med (2009) 7.95
Topics in pediatric leukemia--acute lymphoblastic leukemia. MedGenMed (2005) 0.98
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science (1992) 16.38
Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization. Proc Natl Acad Sci U S A (1986) 12.92
Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet (2001) 11.06
Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature (2001) 10.96
PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet (1999) 6.18
The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell (1999) 6.08
Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc Natl Acad Sci U S A (1994) 5.74
Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosomes Cancer (1994) 5.52
Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas. Nat Genet (2001) 4.96
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev (1994) 4.95
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene. Nat Genet (2000) 4.13
Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J Virol (2004) 4.12
Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. Lancet (2000) 3.68
Cloned pigs produced by nuclear transfer from adult somatic cells. Nature (2000) 3.51
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization. Proc Natl Acad Sci U S A (1992) 3.25
Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation. EMBO J (1998) 3.12
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol Cell Biol (1997) 3.10
Drug dosage and remission duration in childhood lymphocytic leukemia. Cancer (1971) 3.04
Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma. Proc Natl Acad Sci U S A (1998) 2.80
Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M. Nat Genet (1996) 2.77
Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization. Cancer Res (1998) 2.44
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes Dev (1995) 2.41
The proximity of DNA sequences in interphase cell nuclei is correlated to genomic distance and permits ordering of cosmids spanning 250 kilobase pairs. Genomics (1989) 2.39
"Total therapy" studies of acute lymphocytic leukemia in children. Current results and prospects for cure. Cancer (1972) 2.28
Indoor moulds and asthma. J R Soc Health (1988) 2.19
Central nervous system therapy and combination chemotherapy of childhood lymphocytic leukemia. Blood (1971) 2.18
Sources and incidence of airborne Aspergillus fumigatus (Fres). Clin Allergy (1976) 2.17
Segmentation of confocal microscope images of cell nuclei in thick tissue sections. J Microsc (1999) 2.12
Asthma admissions and thunderstorms: a study of pollen, fungal spores, rainfall, and ozone. QJM (2001) 2.10
Comparative genomic hybridization: a rapid new method for detecting and mapping DNA amplification in tumors. Semin Cancer Biol (1993) 2.09
Protozoa as sources of antigen in 'humidifier fever'. Nature (1976) 2.06
Treatment of acute lymphoblastic leukemia. 30 years' experience at St. Jude Children's Research Hospital. N Engl J Med (1993) 1.99
Prevention of central nervous system leukemia by irradiation. Cancer (1973) 1.96
'Allogeneic marrow transplantation in children with acute leukemia: a practice whose time has gone': twenty years later. Leukemia (2009) 1.95
Rapid loss of Oct-4 and pluripotency in cultured rodent blastocysts and derivative cell lines. Biol Reprod (2003) 1.91
Genetic analysis of benign, low-grade, and high-grade ovarian tumors. Cancer Res (1995) 1.91
Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization. Science (1990) 1.90
BAC microarray analysis of 15q11-q13 rearrangements and the impact of segmental duplications. J Med Genet (2004) 1.87
Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features. Am J Pathol (2000) 1.86
A comparison of noncontrast computerized tomography with excretory urography in the assessment of acute flank pain. J Urol (1999) 1.85
Five-year follow-up of "total therapy" of childhood lymphocytic leukemia. JAMA (1971) 1.84
An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer. Cancer Res (2000) 1.81
Computer image analysis of comparative genomic hybridization. Cytometry (1995) 1.80
High resolution deletion analysis of constitutional DNA from neurofibromatosis type 2 (NF2) patients using microarray-CGH. Hum Mol Genet (2001) 1.79
Cytogenetic analysis by in situ hybridization with fluorescently labeled nucleic acid probes. Cold Spring Harb Symp Quant Biol (1986) 1.77
Dual inactivation of RB and p53 pathways in RAS-induced melanomas. Mol Cell Biol (2001) 1.73
Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin. Cancer Res (2000) 1.67
Mechanisms of inactivation of E-cadherin in breast cancer cell lines. Cancer Res (1998) 1.61
Selecting treatment for children with acute lymphoblastic leukemia. J Clin Oncol (1996) 1.57
Fungal spores in lung and sputum. Clin Allergy (1978) 1.55
Cessation of therapy during complete remission of childhood acute lymphocytic leukemia. N Engl J Med (1974) 1.55
Clinical applications of fluorescence in situ hybridization. Genet Anal Tech Appl (1991) 1.52
Bacterial characterization by flow cytometry. Science (1983) 1.52
Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure. AIDS Res Hum Retroviruses (2008) 1.46
Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation. Int J Radiat Biol (1992) 1.43
Detection of aneuploidy involving chromosomes 13, 18, or 21, by fluorescence in situ hybridization (FISH) to interphase and metaphase amniocytes. Am J Hum Genet (1991) 1.41
Fluorescence in situ hybridization to interphase cell nuclei in suspension allows flow cytometric analysis of chromosome content and microscopic analysis of nuclear organization. Hum Genet (1988) 1.41
A study of "total therapy" of acute lymphocytic leukemia in children. J Pediatr (1968) 1.40
Molecular cytogenetic analysis of Spitz nevi shows clear differences to melanoma. J Invest Dermatol (1999) 1.39
Results of a changing treatment philosophy for children with stage I Hodgkin's disease: a 35-year experience. Med Pediatr Oncol (1991) 1.39
Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. J Clin Invest (1996) 1.32
Novel risk stratification of patients with neuroblastoma by genomic signature, which is independent of molecular signature. Oncogene (2007) 1.31
Difluoromethylornithine chemoprevention of epidermal carcinogenesis in K14-HPV16 transgenic mice. Cancer Res (1999) 1.30
Regional variations in grass pollen seasons in the UK, long-term trends and forecast models. Clin Exp Allergy (1999) 1.28
Rapid human chromosome aberration analysis using fluorescence in situ hybridization. Int J Radiat Biol (1989) 1.28
Coordinated treatment of childhood rhabdomyosarcoma with surgery, radiotherapy, and combination chemotherapy. Cancer Res (1972) 1.25
Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes. Genomics (1991) 1.25
A physical map of chromosome 20 established using fluorescence in situ hybridization and digital image analysis. Genomics (1995) 1.24
Stromal-epithelial interactions in the progression of ovarian cancer: influence and source of tumor stromal cells. Mol Cell Endocrinol (2001) 1.22
Relationships between airborne fungal spore concentration of Cladosporium and the summer climate at two sites in Britain. Int J Biometeorol (2003) 1.20
Nine years' experience with "total therapy" of childhood acute lymphocytic leukemia. Pediatrics (1972) 1.17
Fryns syndrome phenotype caused by chromosome microdeletions at 15q26.2 and 8p23.1. J Med Genet (2005) 1.16
Lymphosarcoma, Hodgkin's disease and leukemia in bone. Clin Orthop Relat Res (1967) 1.16
Studies of murine leukemia viruses. I. Detection of Moloney and Rauscher leukemia viruses by indirect immunofluorescence. Proc Soc Exp Biol Med (1966) 1.14
Deletion of chromosome 17p loci in breast cancer cells detected by fluorescence in situ hybridization. Cancer Res (1992) 1.11
Therapy of localized and regional lymphosarcoma of childhood. Cancer (1971) 1.11
Fluorescence in situ hybridization to Y chromosomes in decondensed human sperm nuclei. Mol Reprod Dev (1990) 1.11
Analyses of brain tumor cell lines confirm a simple model of relationships among fluorescence in situ hybridization, DNA index, and comparative genomic hybridization. Genes Chromosomes Cancer (1997) 1.10
Measurement of sister chromatid exchanges at very low bromodeoxyuridine substitution levels using a monoclonal antibody in Chinese hamster ovary cells. Cancer Res (1985) 1.09
Differentiating juvenile myelomonocytic leukemia from infectious disease. Blood (1998) 1.09
High resolution dual laser flow cytometry. J Histochem Cytochem (1978) 1.09
Fluorescence in situ hybridization with DNA probes. Methods Cell Biol (1990) 1.09
Flow karyotyping and sorting of human chromosomes. Cold Spring Harb Symp Quant Biol (1986) 1.09
The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27. Endocrinology (1992) 1.08
Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization. Cytogenet Cell Genet (1992) 1.07
Detection of aneuploidy and aneuploidy-inducing agents in human lymphocytes using fluorescence in situ hybridization with chromosome-specific DNA probes. Mutat Res (1990) 1.05
Detection of aneuploid human sperm by fluorescence in situ hybridization: evidence for a donor difference in frequency of sperm disomic for chromosomes 1 and Y. Am J Hum Genet (1993) 1.05
Combined modality therapy of acute lymphocytic leukemia. Cancer (1975) 1.04
Transgenic rats carrying the mouse renin gene--morphological characterization of a low-renin hypertension model. Kidney Int (1992) 1.03
Molecular cytogenetics of human breast cancer. Cold Spring Harb Symp Quant Biol (1994) 1.02
Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei. J Cell Sci (1989) 1.01
Comparative genomic hybridization analysis of archival formalin-fixed paraffin-embedded uveal melanomas. Cancer Genet Cytogenet (1996) 0.99
Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector. Dev Dyn (1998) 0.99
Efficient, interactive, and three-dimensional segmentation of cell nuclei in thick tissue sections. Cytometry (1998) 0.98
6-Mercaptopurine dosage. Lancet (1987) 0.98
Treatment of acute leukemia. Pediatr Clin North Am (1976) 0.98
Survival of children with neuroblastoma treated with combination chemotherapy. J Pediatr (1968) 0.98
An efficient method for selecting unique-sequence clones from DNA libraries and its application to fluorescent staining of human chromosome 21 using in situ hybridization. Genomics (1989) 0.97
Genomic microarray analysis identifies candidate loci in patients with corpus callosum anomalies. Neurology (2005) 0.97