Published in Bioorg Med Chem Lett on September 18, 2000
5-Methoxy-methyl-4-phen-oxy-1H-pyrazol-3-ol. Acta Crystallogr Sect E Struct Rep Online (2009) 2.00
Sequence determinants of a specific inactive protein kinase conformation. Chem Biol (2013) 1.78
Novel host response therapeutic approaches to treat periodontal diseases. Periodontol 2000 (2007) 1.44
A new screening assay for allosteric inhibitors of cSrc. Nat Chem Biol (2009) 1.16
Modified AutoDock for accurate docking of protein kinase inhibitors. J Comput Aided Mol Des (2002) 0.89
Conformation-selective inhibitors reveal differences in the activation and phosphate-binding loops of the tyrosine kinases Abl and Src. ACS Chem Biol (2013) 0.80
Crystal structure of (Z)-ethyl 3-[2-(5-methyl-7-nitro-1H-indole-2-carbon-yl)hydrazinyl-idene]butano-ate. Acta Crystallogr E Crystallogr Commun (2015) 0.75
Strategies to design pyrazolyl urea derivatives for p38 kinase inhibition: a molecular modeling study. J Comput Aided Mol Des (2007) 0.75
THE MEASUREMENT OF SYMPATHETIC VASOCONSTRICTOR ACTIVITY IN THE LOWER EXTREMITIES. J Clin Invest (1930) 32.02
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell (1991) 6.14
Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem (1997) 5.14
'Animals under our care'--whose care, and for how long? Vet Rec (1998) 4.39
Critical period effects in second language learning: the influence of maturational state on the acquisition of English as a second language. Cogn Psychol (1989) 4.27
The heat resistance of bacterial spores at various water activities. J Gen Microbiol (1966) 4.23
An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. Oncogene (2009) 4.10
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem (1988) 4.06
Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein. J Biol Chem (1986) 3.67
Evaluation of a polymerase chain reaction for the diagnosis of tuberculosis. Tubercle (1991) 3.58
Biocompatible surfactants for water-in-fluorocarbon emulsions. Lab Chip (2008) 3.28
Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proc Natl Acad Sci U S A (1999) 3.19
Psychiatric tourism is overloading London beds. BMJ (1995) 2.95
Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4. J Exp Med (1985) 2.92
Who is speaking for children and adolescents and for their health at the policy level? BMJ (2000) 2.75
Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. J Clin Invest (1990) 2.56
Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1. J Immunol (1991) 2.52
A freely diffusible form of Sonic hedgehog mediates long-range signalling. Nature (2001) 2.50
Physician-performed point-of-care echocardiography using a laptop platform compared with physical examination in the cardiovascular patient. J Am Coll Cardiol (2001) 2.47
Worldwide esophageal cancer collaboration. Dis Esophagus (2009) 2.41
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
Biological properties of a CD4 immunoadhesin. Nature (1990) 2.05
Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease. J Exp Med (1999) 2.00
Imidotitanium complexes as hydroamination catalysts: substantially enhanced reactivity from an unexpected cyclopentadienide/amide ligand exchange. J Am Chem Soc (2001) 1.90
Shared mental health care in Canada. Can J Psychiatry (1997) 1.88
Comparative roles of the Arg-Gly-Asp sequence present in the Bordetella pertussis adhesins pertactin and filamentous hemagglutinin. Infect Immun (1992) 1.85
Attitudes of patients to randomised clinical trials of cancer therapy. Eur J Cancer (1998) 1.85
STUDIES ON THE ACTIVITY OF THE LUMBAR SYMPATHETIC NERVOUS SYSTEM. Ann Surg (1930) 1.83
Nature of glomerular dysfunction in pre-eclampsia. Kidney Int (1998) 1.81
A whole-genome radiation hybrid panel for bovine gene mapping. Mamm Genome (1997) 1.77
Production of cytotoxic factor in the spleen of dengue virus-infected mice. Immunology (1980) 1.73
Effect of cyclophosphamide upon the immune response in Wegener's granulomatosis. N Engl J Med (1971) 1.70
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures. Am J Physiol (1999) 1.66
Eph signaling is required for segmentation and differentiation of the somites. Genes Dev (1998) 1.65
Antitumor activity of sorafenib in FLT3-driven leukemic cells. Leukemia (2007) 1.65
PUBLIC HEALTH ENGINEERING: SURVEY OF CONNECTICUT'S SHORE BATHING WATERS. Am J Public Health Nations Health (1932) 1.64
Rheumatoid factor-producing cells detected by direct hemolytic plaque assay. J Clin Invest (1976) 1.62
Complement fixation by rheumatoid factor. J Clin Invest (1975) 1.60
Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence. Br J Pharmacol (2010) 1.59
What the doctor thought and did: Sir James Crichton-Browne (1840-1938). Med Hist (1995) 1.58
Altered lymphocyte reactivity in rheumatoid arthritis. Arthritis Rheum (1976) 1.58
CHANGES IN THE VASOMOTOR REACTION ASSOCIATED WITH GLOMUS TUMORS. J Clin Invest (1937) 1.57
General psychiatry in no-man's land. Br J Psychiatry (1997) 1.57
SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport. Am J Physiol Renal Physiol (2001) 1.54
Monoparesis. Complication of constant positive airways pressure. Arch Dis Child (1975) 1.54
Salicylate hepatotoxicity in patients with juvenile rheumatoid arthritis. Arthritis Rheum (1973) 1.53
Ephrin-B regulates the Ipsilateral routing of retinal axons at the optic chiasm. Neuron (2000) 1.52
Simulated workplace protection factor study of powered air-purifying and supplied air respirators. AIHAJ (2001) 1.52
Marital status, life-strains and depression. Am Sociol Rev (1977) 1.48
Experimental evaluation of rodent exclusion methods to reduce hantavirus transmission to humans in rural housing. Am J Trop Med Hyg (1997) 1.47
Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis. Proc Natl Acad Sci U S A (1986) 1.44
Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors. J Androl (1993) 1.44
N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage. Biochem J (1992) 1.43
Bone-marrow transplantation in the Maroteaux-Lamy syndrome (mucopolysaccharidosis type VI). Biochemical and clinical status 24 months after transplantation. N Engl J Med (1984) 1.43
Percutaneous transthoracic needle aspiration biopsy: a comprehensive review of its current role in the diagnosis and treatment of lung tumors. Chest (1998) 1.42
Allergic contact dermatitis from lignocaine: report of 29 cases and review of the literature. Contact Dermatitis (1998) 1.42
Arthrogryposis in the foal and its possible relation to autosomal trisomy. Equine Vet J (1997) 1.41
Patient experiences with multiband full dynamic range compression. Ear Hear (1992) 1.41
Chronic therapy with recombinant tumor necrosis factor-alpha in autoimmune NZB/NZW F1 mice. Clin Immunol Immunopathol (1989) 1.40
Effects of various gases on the survival of dried bacteria during storage. Appl Microbiol (1973) 1.40
A national survey of in-patient diabetes services in the United Kingdom. Diabet Med (2007) 1.39
Is nursing research the key to raising standards of care? Nurs Times (2002) 1.39
The farming crisis. Vet Rec (1999) 1.38
Superficial tinea infections. Am Fam Physician (1993) 1.38
Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4. J Virol (1989) 1.38
Reproducibility of measurements of cardiac output in newborn infants by Doppler ultrasound. Arch Dis Child (1990) 1.36
NT-3, like NGF, is required for survival of sympathetic neurons, but not their precursors. Dev Biol (1999) 1.35
The long-term course of cyclosporine-associated chronic nephropathy. Kidney Int (1988) 1.34
In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals. Clin Exp Metastasis (1995) 1.32
Affective startle modulation in clinical depression: preliminary findings. Biol Psychiatry (1999) 1.32
Canine immunoglobulins. I. Evidence for six immunoglobulin classes. J Immunol (1967) 1.31
Tumor invasion as dysregulated cell motility. Semin Cancer Biol (2001) 1.31
Cellular profile and cytokine production at prosthetic interfaces. Study of tissues retrieved from revised hip and knee replacements. J Bone Joint Surg Br (1998) 1.30
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harb Symp Quant Biol (2009) 1.29
Hypogammaglobulinemia associated with accelerated catabolism of IgG secondary to its inteaction with an IgG-reactive monoclonal IgM. J Clin Invest (1971) 1.29
Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation. N Engl J Med (1989) 1.29
The relationship between antibody affinity and the efficiency of complement fixation. J Immunol (1970) 1.28
The small GTP-binding protein Rho1p is localized on the Golgi apparatus and post-Golgi vesicles in Saccharomyces cerevisiae. J Cell Biol (1991) 1.26
Suppression of murine collagen-induced arthritis with monoclonal anti-Ia antibodies and augmentation with IFN-gamma. J Immunol (1988) 1.26
Likelihood of malignancy in a solitary pulmonary nodule: comparison of Bayesian analysis and results of FDG-PET scan. Chest (1997) 1.25
Peptide repeats in a mussel glue protein: theme and variations. Biochemistry (1985) 1.25
Production of pro-inflammatory cytokines correlates with the symptoms of acute sickness behaviour in humans. Psychol Med (2004) 1.24
The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain. Development (1997) 1.23
Electroporation of single cells and tissues with an electrolyte-filled capillary. Anal Chem (2001) 1.23
Minimally invasive localization of oncolytic herpes simplex viral therapy of metastatic pleural cancer. Cancer Gene Ther (2006) 1.23
Use of a calcium sulfate-based bone graft substitute for benign bone lesions. Orthopedics (2001) 1.22
Red cell volume and cardiac output in anaemic preterm infants. Arch Dis Child (1990) 1.22
The involvement of human tumor necrosis factors-alpha and -beta in the mixed lymphocyte reaction. J Immunol (1988) 1.20
Characterization of single-cell electroporation by using patch-clamp and fluorescence microscopy. Biophys J (2000) 1.20
Neurological findings in complex regional pain syndromes--analysis of 145 cases. Acta Neurol Scand (2000) 1.19
Evidence for the validity and reliability of the ALS assessment questionnaire: the ALSAQ-40. Amyotroph Lateral Scler Other Motor Neuron Disord (1999) 1.19
1.56 A structure of mature truncated human fibroblast collagenase. Proteins (1994) 1.17
Fetal growth retardation in rats from different levels of hypoxia. Biol Neonate (1986) 1.16
Interleukin-1 beta, human leukocyte antigen HLA-DR alpha, and transforming growth factor-beta expression in endometrium, placenta, and placental membranes. Am J Obstet Gynecol (1990) 1.15
Twin-to-twin pancreas transplantation: reversal and reenactment of the pathogenesis of type I diabetes. Trans Assoc Am Physicians (1984) 1.15
Cell contact between T cells and synovial fibroblasts causes induction of adhesion molecules and cytokines. J Leukoc Biol (1993) 1.15
Extrageniculate vision in hemianopic humans: saccade inhibition by signals in the blind field. Science (1990) 1.14
Induction of human IgE synthesis by CD4+ T cell clones. Requirement for interleukin 4 and low molecular weight B cell growth factor. J Exp Med (1989) 1.14
IC14, an anti-CD14 antibody, inhibits endotoxin-mediated symptoms and inflammatory responses in humans. J Immunol (2001) 1.14