Published in J Immunol on October 01, 2000
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med (2001) 8.60
Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J Exp Med (2002) 2.96
Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization. Proc Natl Acad Sci U S A (2005) 2.35
Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection. Am J Pathol (2004) 2.27
A database of bacterial lipoproteins (DOLOP) with functional assignments to predicted lipoproteins. J Bacteriol (2006) 1.76
Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. J Clin Invest (2008) 1.54
Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A. Infect Immun (2003) 1.37
Helicobacter pylori preferentially induces interleukin 12 (IL-12) rather than IL-6 or IL-10 in human dendritic cells. Infect Immun (2003) 1.36
Campylobacter jejuni induces maturation and cytokine production in human dendritic cells. Infect Immun (2006) 1.22
Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with Toll-like receptor agonists. Immunology (2004) 1.17
The Mycobacterium tuberculosis complex-restricted gene cfp32 encodes an expressed protein that is detectable in tuberculosis patients and is positively correlated with pulmonary interleukin-10. Infect Immun (2003) 1.07
Viable Borrelia burgdorferi enhances interleukin-10 production and suppresses activation of murine macrophages. Infect Immun (2007) 1.01
Dendritic cells: immune saviors or Achilles' heel? Infect Immun (2001) 0.98
Regulation of miR-24, miR-30b, and miR-142-3p during macrophage and dendritic cell differentiation potentiates innate immunity. J Leukoc Biol (2015) 0.96
Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes. Diagn Pathol (2009) 0.95
Dendritic cells phagocytose and are activated by Treponema pallidum. Infect Immun (2001) 0.94
Functional changes of dendritic cells derived from allogeneic partial liver graft undergoing acute rejection in rats. World J Gastroenterol (2003) 0.94
Role of toll-like receptors in multiple sclerosis. Am J Clin Exp Immunol (2013) 0.94
SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells. PLoS One (2012) 0.94
Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen. Vaccine (2008) 0.93
Oral mucosal dendritic cells and periodontitis: many sides of the same coin with new twists. Periodontol 2000 (2007) 0.92
Critical role of M. tuberculosis for dendritic cell maturation to induce collagen-induced arthritis in H-2b background of C57BL/6 mice. Immunology (2006) 0.91
Dendritic cell activation and maturation induced by mucosal fluid from women with bacterial vaginosis. Clin Immunol (2007) 0.90
Lipoprotein-dependent and -independent immune responses to spirochetal infection. Clin Diagn Lab Immunol (2005) 0.90
Mucopolysaccharide diseases: a complex interplay between neuroinflammation, microglial activation and adaptive immunity. J Inherit Metab Dis (2013) 0.89
Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer. Infect Agent Cancer (2012) 0.89
Prolongation of liver allograft survival by dendritic cells modified with NF-kappaB decoy oligodeoxynucleotides. World J Gastroenterol (2004) 0.86
Interferon-gamma Added During Bacillus Calmette-Guerin Induced Dendritic Cell Maturation Stimulates Potent Th1 Immune Responses. J Transl Med (2003) 0.85
Antigen capture of Porphyromonas gingivalis by human macrophages is enhanced but killing and antigen presentation are reduced by endotoxin tolerance. Infect Immun (2007) 0.83
Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists. Med Microbiol Immunol (2008) 0.83
Targeting TLR2 for vaccine development. J Immunol Res (2014) 0.83
Enhanced maturation and functional capacity of monocyte-derived immature dendritic cells by the synthetic immunomodulator Murabutide. Immunology (2001) 0.82
Endocarditis-associated oral streptococci promote rapid differentiation of monocytes into mature dendritic cells. Infect Immun (2005) 0.81
Effect of mucosal fluid from women with bacterial vaginosis on HIV trans-infection mediated by dendritic cells. Virology (2008) 0.80
Analysis of the toll-like receptor 2-2 (TLR2-2) and TLR4 mRNA expression in the intestinal mucosal immunity of broilers fed on diets supplemented with nickel chloride. Int J Environ Res Public Health (2014) 0.79
S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS Pathog (2016) 0.79
Toll-like receptor 2 signalling and inflammation. Ann Rheum Dis (2005) 0.78
Distribution of Toll-like receptor 1 and Toll-like receptor 2 in human lymphoid tissue. Immunology (2003) 0.78
NF-kappaB activation and zinc finger protein A20 expression in mature dendritic cells derived from liver allografts undergoing acute rejection. World J Gastroenterol (2003) 0.77
Galectin-3 regulates the innate immune response of human monocytes. J Infect Dis (2012) 0.76
Enhanced bleaching treatment: opportunities for immune-assisted melanocyte suicide in vitiligo. Exp Dermatol (2014) 0.75
Divergent Functions of TLR2 on Hematopoietic and Nonhematopoietic Cells during Chronic Mycobacterium tuberculosis Infection. J Immunol (2016) 0.75
Effects of histamine and its antagonists on murine T-cells and bone marrow-derived dendritic cells. Drug Des Devel Ther (2015) 0.75
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med (1999) 9.23
Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science (1991) 8.85
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science (1999) 8.63
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol (2001) 6.62
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature (1998) 6.49
Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science (1991) 6.12
Factors affecting the transformation of Escherichia coli strain chi1776 by pBR322 plasmid DNA. Gene (1978) 5.15
An antimicrobial activity of cytolytic T cells mediated by granulysin. Science (1998) 5.02
The development of close relationships in Japan and the United States: paths of symbiotic harmony and generative tension. Child Dev (2001) 4.96
Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA. Cell (1986) 4.66
Induction of direct antimicrobial activity through mammalian toll-like receptors. Science (2001) 4.46
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism. Nat Immunol (2001) 4.13
Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins. Infect Immun (1990) 4.10
Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J Immunol (2000) 4.10
The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Annu Rev Immunol (1999) 4.10
Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway. Nat Immunol (2000) 3.96
Local production of tumor necrosis factor and IFN-gamma in tuberculous pleuritis. J Immunol (1990) 3.85
Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway. Proc Natl Acad Sci U S A (2001) 3.65
Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement. Nature (1987) 3.42
Identification and localization of integral membrane proteins of virulent Treponema pallidum subsp. pallidum by phase partitioning with the nonionic detergent triton X-114. Infect Immun (1988) 3.42
A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J Clin Invest (1998) 3.41
Differential effects of cytolytic T cell subsets on intracellular infection. Science (1997) 3.39
Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulation. Proc Natl Acad Sci U S A (1986) 3.28
Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science (1997) 3.23
Outer membrane ultrastructure explains the limited antigenicity of virulent Treponema pallidum. Proc Natl Acad Sci U S A (1989) 3.17
Cytokine patterns in the pathogenesis of human leishmaniasis. J Clin Invest (1993) 3.15
Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. J Immunol (2000) 3.10
Cytokine production at the site of disease in human tuberculosis. Infect Immun (1993) 3.04
Cytokine production induced by Mycobacterium tuberculosis lipoarabinomannan. Relationship to chemical structure. J Immunol (1992) 3.03
Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi. Mol Microbiol (2000) 3.00
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. Nature (1998) 2.98
Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol Microbiol (1995) 2.92
Cytokine patterns of immunologically mediated tissue damage. J Immunol (1992) 2.72
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity (1995) 2.70
Increased amplification of pBR322 plasmid deoxyribonucleic acid in Escherichia coli K-12 strains RR1 and chi1776 grown in the presence of high concentrations of nucleoside. J Bacteriol (1979) 2.55
Sensitive detection of Treponema pallidum by using the polymerase chain reaction. J Clin Microbiol (1991) 2.51
Rapid and simple removal of contaminating RNA from plasmid DNA without the use of RNase. Anal Biochem (1981) 2.51
T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection. J Clin Invest (1994) 2.51
Histopathologic and molecular alterations in bronchial epithelium in habitual smokers of marijuana, cocaine, and/or tobacco. J Natl Cancer Inst (1998) 2.34
Glucocorticoid receptor mutants that define a small region sufficient for enhancer activation. Science (1987) 2.33
Nonpeptide ligands for human gamma delta T cells. Proc Natl Acad Sci U S A (1994) 2.33
Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes. Mol Cell Biol (1998) 2.32
The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins. J Cell Biol (1990) 2.32
Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody. J Exp Med (1992) 2.30
Tracheobronchial histopathology in habitual smokers of cocaine, marijuana, and/or tobacco. Chest (1997) 2.28
Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis. J Immunol (1989) 2.27
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. Clin Cancer Res (2001) 2.25
Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol (2001) 2.24
Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis. Infect Immun (1998) 2.23
In situ demonstration of T lymphocyte subsets in granulomatous inflammation: leprosy, rhinoscleroma and sarcoidosis. Clin Exp Immunol (1983) 2.21
The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2). J Cell Sci (2000) 2.21
Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid. J Clin Microbiol (1991) 2.20
Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family. Infect Immun (1999) 2.18
Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides. J Immunol (2000) 2.16
Major integral membrane protein immunogens of Treponema pallidum are proteolipids. Infect Immun (1989) 2.15
Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family. J Bacteriol (1996) 2.14
CD1c restricts responses of mycobacteria-specific T cells. Evidence for antigen presentation by a second member of the human CD1 family. J Immunol (1996) 2.13
MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components. J Immunol (2001) 2.12
Monoclonal antibody with hemagglutination, immobilization, and neutralization activities defines an immunodominant, 47,000 mol wt, surface-exposed immunogen of Treponema pallidum (Nichols). J Exp Med (1984) 2.11
Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct. J Immunol (1991) 2.09
Murine monoclonal antibodies specific for virulent Treponema pallidum (Nichols). Infect Immun (1982) 2.08
The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules. Immunity (1997) 2.07
Binding and antigen presentation of ceramide-containing glycolipids by soluble mouse and human CD1d molecules. J Exp Med (1999) 2.06
RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. EMBO J (1994) 2.04
The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. J Invest Dermatol (1993) 2.04
Large plasma membrane disruptions are rapidly resealed by Ca2+-dependent vesicle-vesicle fusion events. J Cell Biol (1997) 2.01
Characterization of T cell antigens associated with the cell wall protein-peptidoglycan complex of Mycobacterium tuberculosis. J Immunol (1989) 2.01
T lymphocyte subsets in the skin lesions of patients with leprosy. J Am Acad Dermatol (1983) 2.01
B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J Exp Med (1998) 2.00
Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks. Infect Immun (2000) 2.00
Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy. J Immunol (1993) 2.00
Real-space observation of current-driven domain wall motion in submicron magnetic wires. Phys Rev Lett (2004) 1.99
Interleukin 12 at the site of disease in tuberculosis. J Clin Invest (1994) 1.98
The toll of innate immunity on microbial pathogens. N Engl J Med (1999) 1.98
Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression. J Virol (1983) 1.98
Patching plasma membrane disruptions with cytoplasmic membrane. J Cell Sci (2000) 1.96
CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ alpha beta T cell pool. J Immunol (1999) 1.96
Analysis of fluorescence decay curves by means of the Laplace transformation. Biophys J (1975) 1.96
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med (2001) 1.95
Contraction-induced cell wounding and release of fibroblast growth factor in heart. Circ Res (1995) 1.94
Cloning and expression of Treponema pallidum (Nichols) antigen genes in Escherichia coli. Infect Immun (1983) 1.94
Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J Immunol (2000) 1.94
A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. J Immunol (2000) 1.90
Limited surface exposure of Borrelia burgdorferi outer surface lipoproteins. Proc Natl Acad Sci U S A (1996) 1.90
On the cloning of eukaryotic total poly(A)-RNA populations in Escherichia coli. J Biol Chem (1980) 1.89
Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4. Proc Natl Acad Sci U S A (1997) 1.89
Determination of the cytokine profile in American cutaneous leishmaniasis using the polymerase chain reaction. Clin Exp Immunol (1993) 1.88
Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages. J Immunol (1995) 1.86
Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression. Infect Immun (1996) 1.85