Deferiprone for thalassaemia.

PubWeight™: 0.76‹?›

🔗 View Article (PMID 11052617)

Published in Lancet on October 21, 2000

Authors

M J Pippard, D J Weatherall

Articles cited by this

Deferiprone for thalassaemia. Lancet (2000) 1.39

Articles by these authors

The inhumanity of medicine. BMJ (1995) 13.98

A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16. Nature (1985) 7.34

Evolutionary relationships of human populations from an analysis of nuclear DNA polymorphisms. Nature (1986) 4.84

Alpha-thalassaemia caused by a polyadenylation signal mutation. Nature (1984) 4.41

Effect of human erythropoietin derived from recombinant DNA on the anaemia of patients maintained by chronic haemodialysis. Lancet (1986) 4.04

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin. Nature (1979) 3.75

Molecular basis of length polymorphism in the human zeta-globin gene complex. Proc Natl Acad Sci U S A (1983) 3.27

High incidence of malaria in alpha-thalassaemic children. Nature (1996) 3.12

Absence of malaria-specific mortality in children in an area of hyperendemic malaria. Trans R Soc Trop Med Hyg (1998) 3.09

Recent developments in the molecular genetics of human hemoglobin. Cell (1979) 3.09

The severe form of alpha thalassaemia is caused by a haemoglobin gene deletion. Nature (1974) 3.04

A review of the molecular genetics of the human alpha-globin gene cluster. Blood (1989) 2.84

Highly variable regions of DNA flank the human alpha globin genes. Nucleic Acids Res (1981) 2.83

Molecular characterisation of a hypervariable region downstream of the human alpha-globin gene cluster. EMBO J (1986) 2.77

Globin synthesis in thalassaemia: an in vitro study. Nature (1965) 2.74

A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite. Nature (1988) 2.70

First-trimester fetal diagnosis for haemoglobinopathies: three cases. Lancet (1982) 2.55

DNA "fingerprints" and segregation analysis of multiple markers in human pedigrees. Am J Hum Genet (1986) 2.55

The interaction of alpha-thalassemia and homozygous sickle-cell disease. N Engl J Med (1982) 2.52

Embryonic erythroid differentiation in the human leukemic cell line K562. Proc Natl Acad Sci U S A (1981) 2.42

The molecular basis of alpha-thalassemias: frequent occurrence of dysfunctional alpha loci among non-Asians with Hb H disease. Cell (1979) 2.41

Academia and industry: lessons from the unfortunate events in Toronto. Lancet (1999) 2.39

Survival and desferrioxamine in thalassaemia major. Br Med J (Clin Res Ed) (1982) 2.35

Hemoglobin H disease and mental retardation: a new syndrome or a remarkable coincidence? N Engl J Med (1981) 2.35

Rapid detection and prenatal diagnosis of beta-thalassaemia: studies in Indian and Cypriot populations in the UK. Lancet (1990) 2.33

Detection of breakpoints in submicroscopic chromosomal translocation, illustrating an important mechanism for genetic disease. Lancet (1989) 2.28

Cellular mechanism for the protective effect of haemoglobin S against P. falciparum malaria. Nature (1978) 2.28

Haemoglobin Constant Spring--a chain termination mutant? Nature (1971) 2.25

alpha+-Thalassemia protects children against disease caused by other infections as well as malaria. Proc Natl Acad Sci U S A (1997) 2.19

The spectrum of beta-thalassaemia mutations on the Indian subcontinent: the basis for prenatal diagnosis. Br J Haematol (1991) 2.12

The interaction between Plasmodium falciparum and P. vivax in children on Espiritu Santo island, Vanuatu. Trans R Soc Trop Med Hyg (1997) 2.12

Delta-beta-thalassemia is due to a gene deletion. Cell (1976) 2.12

Erythrocytes deficiency in glycophorin resist invasion by the malarial parasite Plasmodium falciparum. Nature (1982) 2.10

Aplastic crisis due to parvovirus infection in pyruvate kinase deficiency. Lancet (1983) 2.05

Polycythemia associated with a hemoglobinopathy. J Clin Invest (1966) 1.98

Fetal haemoglobin production and the sickle gene in the oases of Eastern Saudi Arabia. Br J Haematol (1978) 1.98

A novel alpha-globin gene arrangement in man. Nature (1980) 1.98

The anaemia of P. falciparum malaria. Br J Haematol (1980) 1.97

Rapid detection of alpha-thalassaemia deletions and alpha-globin gene triplication by multiplex polymerase chain reactions. Br J Haematol (2000) 1.95

Cytosine arabinoside in the treatment of acute myeloblastic leukaemia. Lancet (1971) 1.94

Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia. Proc Natl Acad Sci U S A (1979) 1.94

Two genetic markers closely linked to adult polycystic kidney disease on chromosome 16. Br Med J (Clin Res Ed) (1986) 1.93

The importance of anaemia in cerebral and uncomplicated falciparum malaria: role of complications, dyserythropoiesis and iron sequestration. Q J Med (1986) 1.90

Reliable routine estimation of small amounts of foetal haemoglobin by alkali denaturation. J Clin Pathol (1972) 1.88

Thalassaemia in the British. Br Med J (1973) 1.82

Gene deletions in alpha thalassemia prove that the 5' zeta locus is functional. Proc Natl Acad Sci U S A (1980) 1.80

Benign sickle-cell anaemia. Lancet (1972) 1.79

Clinical features and molecular analysis of the alpha thalassemia/mental retardation syndromes. II. Cases without detectable abnormality of the alpha globin complex. Am J Hum Genet (1990) 1.76

Detection of somatic changes in human cancer DNA by DNA fingerprint analysis. Br J Cancer (1987) 1.74

Glycophorin as a possible receptor for Plasmodium falciparum. Lancet (1982) 1.69

An improved method for the characterization of human haemoglobin mutants: identification of alpha-2-beta-2-95GLU, haemoglobin N (Baltimore). Nature (1965) 1.68

Effects of foetal haemoglobin on susceptibility of red cells to Plasmodium falciparum. Nature (1977) 1.66

Iron absorption and loading in beta-thalassaemia intermedia. Lancet (1979) 1.66

Antenatal diagnosis of thalassaemia major. Br Med J (1978) 1.64

A newly defined X linked mental retardation syndrome associated with alpha thalassaemia. J Med Genet (1991) 1.61

Alpha-thalassemia. Curr Top Hematol (1983) 1.60

Functional disturbance of marrow stromal microenvironment in the myelodysplastic syndromes. Leukemia (2002) 1.59

The anaemia of Plasmodium falciparum malaria. Br Med Bull (1982) 1.59

Thalassemia revisited. Cell (1982) 1.58

Melanesians and Polynesians share a unique alpha-thalassemia mutation. Am J Hum Genet (1985) 1.58

Dissecting the loci controlling fetal haemoglobin production on chromosomes 11p and 6q by the regressive approach. Nat Genet (1996) 1.57

Haemoglobin-H disease due to a unique haemoglobin variant with an elongated alpha-chain. Lancet (1971) 1.55

The pattern of disordered haemoglobin synthesis in homozygous and heterozygous beta-thalassaemia. Br J Haematol (1969) 1.54

Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution. Nucleic Acids Res (1984) 1.54

Haemoglobin Icaria, a new chain-termination mutant with causes alpha thalassaemia. Nature (1974) 1.53

Haemoglobin synthesis in beta-thalassaemia. Nature (1968) 1.52

Characterization of the anaemia of chronic renal failure and the mode of its correction by a preparation of human erythropoietin (r-HuEPO). An investigation of the pharmacokinetics of intravenous erythropoietin and its effects on erythrokinetics. Q J Med (1989) 1.49

Lectin-like polypeptides of P. falciparum bind to red cell sialoglycoproteins. Nature (1983) 1.48

Presence of gene for beta globin in homozygous beta0 thalassaemia. Nature (1976) 1.48

Prevention of iron loading in transfusion-dependent thalassaemia. Lancet (1978) 1.47

The alpha thalassaemias. Cell Mol Life Sci (2009) 1.47

Rearrangement of the T-cell-receptor beta-chain gene in the diagnosis of lymphoproliferative disorders. Lancet (1985) 1.46

Multiple arrangements of the human embryonic zeta globin genes. Nucleic Acids Res (1982) 1.45

Interaction of hemoglobin E and pyrimidine 5' nucleotidase deficiency. Blood (1996) 1.44

Thalassaemia in Sri Lanka: implications for the future health burden of Asian populations. Sri Lanka Thalassaemia Study Group. Lancet (2000) 1.42

First-trimester fetal diagnosis for haemoglobinopathies: report on 200 cases. Lancet (1986) 1.42

Molecular basis for dominantly inherited inclusion body beta-thalassemia. Proc Natl Acad Sci U S A (1990) 1.42

Is the beta thalassaemia trait of clinical importance? Br J Haematol (2008) 1.39

In vivo studies on the relationship between intestinal iron (Fe3+) absorption, hypoxia and erythropoiesis in the mouse. Br J Haematol (1988) 1.39

Defective synthesis of HbE is due to reduced levels of beta E mRNA. Nature (1980) 1.38

Separation of the alpha and beta-chains of human hemoglobin. Nature (1968) 1.37

Fetal haemoglobin and malaria. Lancet (1976) 1.37

Prevention of cerebral malaria in children in Papua New Guinea by southeast Asian ovalocytosis band 3. Am J Trop Med Hyg (1999) 1.36

Plasma ferritin determination as a diagnostic tool. West J Med (1986) 1.34

Reduced erythrocyte survival following clearance of malarial parasitaemia in Thai patients. Br J Haematol (1987) 1.34

Pattern of maternal F-cell production during pregnancy. Lancet (1977) 1.32

Deficient heme synthesis as the cause of noninducibility of hemoglobin synthesis in a Friend erythroleukemia cell line. Cell (1979) 1.32

The increased susceptibility of young red cells to invasion by the malarial parasite Plasmodium falciparum. Br J Haematol (1980) 1.32

Haemoglobin synthesis in alpha-thalassaemia (haemoglobin H disease). Nature (1967) 1.31

The molecular basis of alpha-thalassaemia in Thailand. EMBO J (1984) 1.30

The haemoglobin constitution of infants with the haemoglobin Bart's hydrops foetalis syndrome. Br J Haematol (1970) 1.30

Major rearrangement in the human beta-globin gene cluster. Nature (1981) 1.30

Acanthocytosis, normolipoproteinaemia and multiple tics. Postgrad Med J (1970) 1.29

A second genetic locus for autosomal dominant polycystic kidney disease. Lancet (1988) 1.29

Interaction of malaria with a common form of severe thalassemia in an Asian population. Proc Natl Acad Sci U S A (2009) 1.29

Iron metabolism in haemodialysis patients. A study of the management of iron therapy and overload. Q J Med (1979) 1.28

Prenatal diagnosis of the common haemoglobin disorders. J Med Genet (1985) 1.28

Association of thalassaemia intermedia with a beta-globin gene haplotype. Br J Haematol (1987) 1.28