FrzB-2: a human secreted frizzled-related protein with a potential role in chondrocyte apoptosis.

PubWeight™: 0.85‹?›

🔗 View Article (PMID 11069730)

Published in Osteoarthritis Cartilage on November 01, 2000

Authors

I E James1, S Kumar, M R Barnes, C J Gress, A T Hand, R A Dodds, J R Connor, B R Bradley, D A Campbell, S E Grabill, K Williams, S M Blake, M Gowen, M W Lark

Author Affiliations

1: Department of Bone and Cartilage Biology, SmithKline Beecham Pharmaceuticals, 709 Swedeland Road, King of Prussia, Pennsylvania 19406, USA. Ian_E_James@sbphrd.com

Articles by these authors

The optimization principle in phylogenetic analysis tends to give incorrect topologies when the number of nucleotides or amino acids used is small. Proc Natl Acad Sci U S A (1998) 15.43

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature (1995) 11.89

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ (2008) 10.45

A new method of inference of ancestral nucleotide and amino acid sequences. Genetics (1995) 10.23

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ (2011) 9.44

HhaI methyltransferase flips its target base out of the DNA helix. Cell (1994) 8.72

Incomplete taxon sampling is not a problem for phylogenetic inference. Proc Natl Acad Sci U S A (2001) 8.53

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest (1994) 7.25

Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors. Nucleic Acids Res (1993) 6.15

High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum (2001) 5.87

Cumulative sleepiness, mood disturbance, and psychomotor vigilance performance decrements during a week of sleep restricted to 4-5 hours per night. Sleep (1997) 5.82

Strong coupling of a single photon to a superconducting qubit using circuit quantum electrodynamics. Nature (2004) 4.54

Continental breakup and the ordinal diversification of birds and mammals. Nature (1996) 4.44

Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection. J Immunol (2001) 4.38

A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI. Mem Inst Oswaldo Cruz (2009) 4.27

Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow. Blood (2001) 4.22

Folding funnels, binding funnels, and protein function. Protein Sci (1999) 4.22

Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine. Cell (1993) 3.96

Understanding human disease mutations through the use of interspecific genetic variation. Hum Mol Genet (2001) 3.95

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem (1998) 3.88

Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am J Physiol Endocrinol Metab (2006) 3.84

LMNA, encoding lamin A/C, is mutated in partial lipodystrophy. Nat Genet (2000) 3.73

An interleukin 1 like factor stimulates bone resorption in vitro. Nature (1984) 3.71

HEREDITARY DEGENERATION OF THE RAT RETINA. Br J Ophthalmol (1938) 3.65

Plasma immunoglobulin concentrations in a West African (Gambian) community and in a group of healthy British adults. Clin Exp Immunol (1968) 3.53

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin Invest (1990) 3.39

The relation of body fat mass and distribution to markers of chronic inflammation. Int J Obes Relat Metab Disord (2001) 3.39

The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell (2000) 3.39

Angiogenesis induced by degradation products of hyaluronic acid. Science (1985) 3.37

p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell (1998) 3.27

Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase. Science (1991) 3.27

Folding funnels and binding mechanisms. Protein Eng (1999) 3.25

Discrimination of human macrophages and dendritic cells by means of monoclonal antibodies. Scand J Immunol (1986) 3.11

Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1981) 3.07

Divergence time estimates for the early history of animal phyla and the origin of plants, animals and fungi. Proc Biol Sci (1999) 3.04

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med (1999) 3.01

Admission after mild head injury: benefits and costs. Br Med J (Clin Res Ed) (1982) 2.99

Role of angiogenesis in patients with cerebral ischemic stroke. Stroke (1994) 2.96

Inhibition of extracellular signal-regulated kinase enhances Ischemia/Reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart. Circ Res (2000) 2.93

DNA markers define two major phylogenetic lineages of Trypanosoma cruzi. Mol Biochem Parasitol (1996) 2.90

Variations of serum-calcium in the rabbit. Biochem J (1932) 2.87

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes. Nature (1984) 2.85

Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis. Antimicrob Agents Chemother (2005) 2.74

BINOCULAR VISION IN MINERS. Br J Ophthalmol (1948) 2.73

Amino acid sequence of human von Willebrand factor. Biochemistry (1986) 2.73

Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures. Genes Dev (1997) 2.60

Rapid rise in the incidence of type 2 diabetes from 1987 to 1996: results from the San Antonio Heart Study. Arch Intern Med (1999) 2.58

Bradykinin as a pain mediator: receptors are localized to sensory neurons, and antagonists have analgesic actions. Proc Natl Acad Sci U S A (1988) 2.57

A new nomenclature for IL-1-family genes. Trends Immunol (2001) 2.57

A randomized trial of alternative two- and three-dose hepatitis B vaccination regimens in adolescents: antibody responses, safety, and immunologic memory. Pediatrics (2001) 2.55

Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase. J Biol Chem (1996) 2.55

Prognostic impact of lymphadenectomy in uterine serous cancer. BJOG (2012) 2.54

Tempo and mode of nucleotide substitutions in gag and env gene fragments in human immunodeficiency virus type 1 populations with a known transmission history. J Virol (1997) 2.47

Does nonneutral evolution shape observed patterns of DNA variation in animal mitochondrial genomes? Annu Rev Genet (2001) 2.46

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion. Circ Res (1994) 2.46

Antigens associated with Plasmodium falciparum infections in man. Lancet (1969) 2.45

Overexpression of the c-erbB-2 oncoprotein in human breast carcinomas: immunohistological assessment correlates with gene amplification. Lancet (1987) 2.44

Human origins and analysis of mitochondrial DNA sequences. Science (1992) 2.43

Productive infection of cerebellar granule cell neurons by JC virus in an HIV+ individual. Neurology (2003) 2.43

Complete protective immunity induced in mice by immunization with the 19-kilodalton carboxyl-terminal fragment of the merozoite surface protein-1 (MSP1[19]) of Plasmodium yoelii expressed in Saccharomyces cerevisiae: correlation of protection with antigen-specific antibody titer, but not with effector CD4+ T cells. J Immunol (1997) 2.43

Report of the Canadian Hypertension Society Consensus Conference: 1. Definitions, evaluation and classification of hypertensive disorders in pregnancy. CMAJ (1997) 2.41

Prevalence of faecal incontinence in adults aged 40 years or more living in the community. Gut (2002) 2.41

Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins. Proc Natl Acad Sci U S A (1989) 2.40

Prevalence of dementia in a rural setting: A report from India. Int J Geriatr Psychiatry (1997) 2.39

Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus. Nat Med (1998) 2.38

Does central obesity reflect "Cushing's disease of the omentum"? Lancet (1997) 2.34

Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts. J Biol Chem (1996) 2.33

Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A (1997) 2.32

Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J Biol Chem (1997) 2.28

International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma. Leukemia (2009) 2.28

Properties of adenyl cyclase and cyclic adenosine 3',5'-monophosphate receptor protein-deficient mutants of Escherichia coli. J Bacteriol (1976) 2.27

Family and parenting interventions for conduct disorder and delinquency: a meta-analysis of randomised controlled trials. Arch Dis Child (2002) 2.24

Production of "authentic" poliovirus RNA-dependent RNA polymerase (3D(pol)) by ubiquitin-protease-mediated cleavage in Escherichia coli. Protein Expr Purif (1999) 2.24

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division. Mol Cell Biol (2000) 2.23

Kinetoplastid mitochondria contain functional tRNAs which are encoded in nuclear DNA and also contain small minicircle and maxicircle transcripts of unknown function. Nucleic Acids Res (1989) 2.22

Enhanced diabetes care to patients of south Asian ethnic origin (the United Kingdom Asian Diabetes Study): a cluster randomised controlled trial. Lancet (2008) 2.21

Improvement of cast nephropathy with plasma exchange depends on the diagnosis and on reduction of serum free light chains. Kidney Int (2008) 2.21

A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis. Neurology (2008) 2.21

Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production. J Biol Chem (1999) 2.17

Detection of convergent and parallel evolution at the amino acid sequence level. Mol Biol Evol (1997) 2.15

A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide. Nat Protoc (2006) 2.14

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J (2000) 2.13

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. J Biol Chem (1998) 2.12

Inhibition of p38 MAP kinase as a therapeutic strategy. Immunopharmacology (2000) 2.12

Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis. Arthritis Rheum (1993) 2.10

The response regulator PhoP is important for survival under conditions of macrophage-induced stress and virulence in Yersinia pestis. Infect Immun (2000) 2.10

Comparison of histidine-tryptophan-ketoglutarate and University of Wisconsin preservation in renal transplantation. Am J Transplant (2007) 2.10

Water supplementation in exclusively breastfed infants during summer in the tropics. Lancet (1991) 2.09

Fulminant EBV(+) T-cell lymphoproliferative disorder following acute/chronic EBV infection: a distinct clinicopathologic syndrome. Blood (2000) 2.09

Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes. J Exp Med (1990) 2.09

Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection. Neurology (2009) 2.08

Differential in vivo expression of collagenase messenger RNA in synovium and cartilage. Quantitative comparison with stromelysin messenger RNA levels in human rheumatoid arthritis and osteoarthritis patients and in two animal models of acute inflammatory arthritis. Arthritis Rheum (1993) 2.08

Anterior interosseus nerve injury following tension band wiring of the olecranon. Injury (2005) 2.08

Mitotic chromosome loss in a disomic haploid of Saccharomyces cerevisiae. Genetics (1975) 2.06

On appetite and its loss. J Clin Oncol (2000) 2.06

Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification. J Biol Chem (1996) 2.06

Cell death by autophagy: facts and apparent artefacts. Cell Death Differ (2011) 2.06