Published in Proteins on January 01, 2001
Protein-protein interactions: structurally conserved residues distinguish between binding sites and exposed protein surfaces. Proc Natl Acad Sci U S A (2003) 3.42
Diversity of protein-protein interactions. EMBO J (2003) 3.35
Deciphering protein-protein interactions. Part I. Experimental techniques and databases. PLoS Comput Biol (2007) 2.84
Structure, function, and evolution of transient and obligate protein-protein interactions. Proc Natl Acad Sci U S A (2005) 2.69
Positive selection at the protein network periphery: evaluation in terms of structural constraints and cellular context. Proc Natl Acad Sci U S A (2007) 2.55
Are protein-protein interfaces more conserved in sequence than the rest of the protein surface? Protein Sci (2004) 2.38
Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins. Nucleic Acids Res (2003) 2.37
Characterization of molecular recognition features, MoRFs, and their binding partners. J Proteome Res (2007) 2.23
A new, structurally nonredundant, diverse data set of protein-protein interfaces and its implications. Protein Sci (2004) 2.11
SCOPPI: a structural classification of protein-protein interfaces. Nucleic Acids Res (2006) 2.06
Evolution of the cytoskeleton. Bioessays (2007) 1.93
Conservation and relative importance of residues across protein-protein interfaces. Proc Natl Acad Sci U S A (2005) 1.75
ProBiS algorithm for detection of structurally similar protein binding sites by local structural alignment. Bioinformatics (2010) 1.72
The many faces of protein-protein interactions: A compendium of interface geometry. PLoS Comput Biol (2006) 1.71
Protein interactions and ligand binding: from protein subfamilies to functional specificity. Proc Natl Acad Sci U S A (2010) 1.71
Composition Profiler: a tool for discovery and visualization of amino acid composition differences. BMC Bioinformatics (2007) 1.64
MultiBind and MAPPIS: webservers for multiple alignment of protein 3D-binding sites and their interactions. Nucleic Acids Res (2008) 1.52
A survey of available tools and web servers for analysis of protein-protein interactions and interfaces. Brief Bioinform (2009) 1.47
Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design. Nucleic Acids Res (2005) 1.45
Gene3D: structural assignment for whole genes and genomes using the CATH domain structure database. Genome Res (2002) 1.29
Oligomeric protein structure networks: insights into protein-protein interactions. BMC Bioinformatics (2005) 1.27
Incorporating background frequency improves entropy-based residue conservation measures. BMC Bioinformatics (2006) 1.27
On the molecular discrimination between adenine and guanine by proteins. Nucleic Acids Res (2001) 1.26
The 1.3-A resolution structure of Nitrosomonas europaea Rh50 and mechanistic implications for NH3 transport by Rhesus family proteins. Proc Natl Acad Sci U S A (2007) 1.26
Residue centrality, functionally important residues, and active site shape: analysis of enzyme and non-enzyme families. Protein Sci (2006) 1.26
Spatial chemical conservation of hot spot interactions in protein-protein complexes. BMC Biol (2007) 1.22
PiSite: a database of protein interaction sites using multiple binding states in the PDB. Nucleic Acids Res (2008) 1.21
SiteEngines: recognition and comparison of binding sites and protein-protein interfaces. Nucleic Acids Res (2005) 1.20
Protein meta-functional signatures from combining sequence, structure, evolution, and amino acid property information. PLoS Comput Biol (2008) 1.19
In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved. Proc Natl Acad Sci U S A (2004) 1.18
Molecular imaging of homodimeric protein-protein interactions in living subjects. FASEB J (2004) 1.17
Signatures of protein biophysics in coding sequence evolution. Curr Opin Struct Biol (2010) 1.17
Side-chain conformational entropy at protein-protein interfaces. Protein Sci (2002) 1.14
Protein interface classification by evolutionary analysis. BMC Bioinformatics (2012) 1.11
Structural basis of hereditary coproporphyria. Proc Natl Acad Sci U S A (2005) 1.08
Computational analyses of the surface properties of protein-protein interfaces. Acta Crystallogr D Biol Crystallogr (2006) 1.05
When monomers are preferred: a strategy for the identification and disruption of weakly oligomerized proteins. Structure (2005) 1.03
Localization of protein-binding sites within families of proteins. Protein Sci (2005) 1.02
A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography. Nat Med (2010) 1.02
Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair. Hum Mutat (2010) 1.02
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction. BMC Bioinformatics (2008) 0.97
Optimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designing. PLoS One (2010) 0.97
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins. BMC Bioinformatics (2007) 0.96
Prediction of protein-protein interaction types using association rule based classification. BMC Bioinformatics (2009) 0.96
Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers. Sci Rep (2015) 0.95
Local packing density is the main structural determinant of the rate of protein sequence evolution at site level. Biomed Res Int (2014) 0.94
A model for the Escherichia coli FtsB/FtsL/FtsQ cell division complex. BMC Struct Biol (2011) 0.93
Subfamily specific conservation profiles for proteins based on n-gram patterns. BMC Bioinformatics (2008) 0.92
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase. Nucleic Acids Res (2006) 0.92
A comparative study of conservation and variation scores. BMC Bioinformatics (2010) 0.91
Physicochemical and residue conservation calculations to improve the ranking of protein-protein docking solutions. Protein Sci (2005) 0.90
Insights into the quaternary association of proteins through structure graphs: a case study of lectins. Biochem J (2005) 0.89
Viral capsid proteins are segregated in structural fold space. PLoS Comput Biol (2013) 0.89
Simplified method to predict mutual interactions of human transcription factors based on their primary structure. PLoS One (2011) 0.86
Identification of amino acid residues of anthrax protective antigen involved in binding with lethal factor. Infect Immun (2002) 0.86
Characterization of the kringle fold and identification of a ubiquitous new class of disulfide rotamers. J Struct Biol (2009) 0.86
Comparing interfacial dynamics in protein-protein complexes: an elastic network approach. BMC Struct Biol (2010) 0.85
Variation in structural location and amino acid conservation of functional sites in protein domain families. BMC Bioinformatics (2005) 0.84
Asymmetric mutation rates at enzyme-inhibitor interfaces: implications for the protein-protein docking problem. Protein Sci (2003) 0.82
Relating the disease mutation spectrum to the evolution of the cystic fibrosis transmembrane conductance regulator (CFTR). PLoS One (2012) 0.81
Computational prediction of the human-microbial oral interactome. BMC Syst Biol (2014) 0.80
Prediction and redesign of protein-protein interactions. Prog Biophys Mol Biol (2014) 0.80
Optimised amino acid specific weighting factors for unbound protein docking. BMC Bioinformatics (2006) 0.80
Background frequencies for residue variability estimates: BLOSUM revisited. BMC Bioinformatics (2007) 0.79
αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia. Proc Natl Acad Sci U S A (2015) 0.79
NMR solution structure of the neurotrypsin Kringle domain. Biochemistry (2008) 0.78
Protein-protein interface detection using the energy centrality relationship (ECR) characteristic of proteins. PLoS One (2014) 0.77
X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure. Protein Sci (2007) 0.77
In silico modeling of human α2C-adrenoreceptor interaction with filamin-2. PLoS One (2014) 0.77
DOCKSCORE: a webserver for ranking protein-protein docked poses. BMC Bioinformatics (2015) 0.77
Tunnel plasticity and quaternary structural integrity of a pentameric protein ring. Protein Sci (2006) 0.77
Protein subunit interfaces: A statistical analysis of hot spots in Sm proteins. J Mol Model (2010) 0.76
Understanding the fabric of protein crystals: computational classification of biological interfaces and crystal contacts. Bioinformatics (2015) 0.76
DynaFace: Discrimination between Obligatory and Non-obligatory Protein-Protein Interactions Based on the Complex's Dynamics. PLoS Comput Biol (2015) 0.76
ECMIS: computational approach for the identification of hotspots at protein-protein interfaces. BMC Bioinformatics (2014) 0.76
Probing binding hot spots at protein-RNA recognition sites. Nucleic Acids Res (2015) 0.76
Combination of scoring schemes for protein docking. BMC Bioinformatics (2007) 0.76
A novel member of the YchN-like fold: solution structure of the hypothetical protein Tm0979 from Thermotoga maritima. Protein Sci (2005) 0.75
Weak conservation of structural features in the interfaces of homologous transient protein-protein complexes. Protein Sci (2015) 0.75
Logistic regression models to predict solvent accessible residues using sequence- and homology-based qualitative and quantitative descriptors applied to a domain-complete X-ray structure learning set. J Appl Crystallogr (2015) 0.75
Comparative Bioinformatic Analysis of Active Site Structures in Evolutionarily Remote Homologues of α,β-Hydrolase Superfamily Enzymes. Acta Naturae (2011) 0.75
Interactome-wide prediction of protein-protein binding sites reveals effects of protein sequence variation in Arabidopsis thaliana. PLoS One (2012) 0.75
Intensification: A resource for amplifying population-genetic signals with protein repeats. J Mol Biol (2016) 0.75
Surface energetics and protein-protein interactions: analysis and mechanistic implications. Sci Rep (2016) 0.75
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