Published in JAMA on December 20, 2000
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ (2009) 22.18
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med (2009) 21.74
Research ethics recommendations for whole-genome research: consensus statement. PLoS Biol (2008) 5.24
What are the effects of the fifth revision of the Declaration of Helsinki? BMJ (2001) 3.17
First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study. BMJ (2014) 2.97
Nivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II Trial. J Clin Oncol (2014) 2.78
The structure and function of research ethics committees in Africa: a case study. PLoS Med (2007) 2.57
Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939--an oral, direct Factor Xa inhibitor--after multiple dosing in healthy male subjects. Eur J Clin Pharmacol (2005) 2.40
Best Practice Guidelines on Publication Ethics: a publisher's perspective. Int J Clin Pract Suppl (2007) 2.24
Resolving the clinical acuity categories "hand motion" and "counting fingers" using the Freiburg Visual Acuity Test (FrACT). Graefes Arch Clin Exp Ophthalmol (2008) 2.15
Informed consent for genetic research on blood stored for more than a decade: a population based study. BMJ (2002) 2.15
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide. Int J Obes (Lond) (2011) 2.08
A randomized, controlled study of once-daily LY2605541, a novel long-acting basal insulin, versus insulin glargine in basal insulin-treated patients with type 2 diabetes. Diabetes Care (2012) 2.08
Preliminary findings of a randomized trial of non-pharmaceutical interventions to prevent influenza transmission in households. PLoS One (2008) 2.04
Pesticide testing on human subjects: weighing benefits and risks. Environ Health Perspect (2005) 2.02
Research ethics review in humanitarian contexts: the experience of the independent ethics review board of Médecins Sans Frontières. PLoS Med (2009) 1.90
Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries. Trials (2010) 1.77
Early diagnosis of Dengue infection using a commercial Dengue Duo rapid test kit for the detection of NS1, IGM, and IGG. Am J Trop Med Hyg (2010) 1.70
A retrospective comparison between 68Ga-DOTA-TOC PET/CT and 18F-DOPA PET/CT in patients with extra-adrenal paraganglioma. Eur J Nucl Med Mol Imaging (2013) 1.63
Health Research Ethics Committees in South Africa 12 years into democracy. BMC Med Ethics (2007) 1.54
Ethical oversight of public health research: can rules and IRBs make a difference in developing countries? Am J Public Health (2002) 1.52
Perceptual relevance of abnormal visual field representations: static visual field perimetry in human albinism. Br J Ophthalmol (2007) 1.51
Relationship between entry into child welfare and mental health service use. Psychiatr Serv (2005) 1.50
Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, glycemic parameters, appetite and energy metabolism in obese, non-diabetic adults. Int J Obes (Lond) (2013) 1.46
The association between anthropometric parameters, the metabolic syndrome and microalbuminuria in black Africans: the SABPA study. Cardiovasc J Afr (2010) 1.45
A Comprehensive Analysis of Authorship in Radiology Journals. PLoS One (2015) 1.43
Assessment of Vitamin D status in a group of Egyptian children with non alcoholic fatty liver disease (multicenter study). Nutr Metab (Lond) (2016) 1.38
Inadequate reporting of research ethics review and informed consent in cluster randomised trials: review of random sample of published trials. BMJ (2011) 1.36
Ethics of conducting research in conflict settings. Confl Health (2009) 1.34
Effects of author contribution disclosures and numeric limitations on authorship trends. Mayo Clin Proc (2010) 1.34
Voluntary participation and informed consent to international genetic research. Am J Public Health (2006) 1.32
Rates and determinants of uptake and use of an internet physical activity and weight management program in office and manufacturing work sites in England: cohort study. J Med Internet Res (2008) 1.32
Length and complexity of US and international HIV consent forms from federal HIV network trials. J Gen Intern Med (2011) 1.28
Global report on preterm birth and stillbirth (6 of 7): ethical considerations. BMC Pregnancy Childbirth (2010) 1.24
Describing randomisation: patients' and the public's preferences compared with clinicians' practice. Br J Cancer (2002) 1.24
Comparison of gadolinium-EOB-DTPA-enhanced and diffusion-weighted liver MRI for detection of small hepatic metastases. Eur Radiol (2010) 1.21
Review of a mock research protocol in functional neuroimaging by Canadian research ethics boards. J Med Ethics (2006) 1.20
(68)Ga-PSMA PET/CT for restaging recurrent prostate cancer: which factors are associated with PET/CT detection rate? Eur J Nucl Med Mol Imaging (2015) 1.18
Sham procedures and the ethics of clinical trials. J R Soc Med (2004) 1.16
Guidelines for randomized clinical trial protocol content: a systematic review. Syst Rev (2012) 1.15
Prevalence and public-health significance of HIV infection and anaemia among pregnant women attending antenatal clinics in south-eastern Nigeria. J Health Popul Nutr (2007) 1.13
Aging might increase myocardial ischemia / reperfusion-induced apoptosis in humans and rats. Age (Dordr) (2011) 1.13
Research on environmental health interventions: ethical problems and solutions. Account Res (2005) 1.13
Polymorphisms of the insertion / deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of data. BMC Nephrol (2005) 1.13
Long-term effects of fingolimod in multiple sclerosis: the randomized FREEDOMS extension trial. Neurology (2015) 1.12
Burden and benefit of psychosocial research at the end of life. J Palliat Med (2008) 1.12
Ethical issues in implementation research: a discussion of the problems in achieving informed consent. Implement Sci (2008) 1.12
Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects. Antimicrob Agents Chemother (2011) 1.12
Where is the supporting evidence for treating mild to moderate chronic obstructive pulmonary disease exacerbations with antibiotics? A systematic review. BMC Med (2008) 1.11
First-in-human trial participants: not a vulnerable population, but vulnerable nonetheless. J Law Med Ethics (2009) 1.11
Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels. PLoS Genet (2010) 1.10
Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children: a double blind and randomized trial [ISRCTN64132371]. BMC Psychiatry (2004) 1.10
Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study). BMC Med Res Methodol (2012) 1.10
Introducing new technologies: protecting subjects of surgical innovation and research. World J Surg (2003) 1.09
Pesticide knowledge, practice and attitude and how it affects the health of small-scale farmers in Uganda: a cross-sectional study. Afr Health Sci (2014) 1.07
Exploring the ethics of clinical research in an urban community. Am J Public Health (2006) 1.06
Safety and efficacy of once-weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes over 84 weeks. Diabetes Care (2012) 1.04
(11)C-Choline PET/CT in castration-resistant prostate cancer patients treated with docetaxel. Eur J Nucl Med Mol Imaging (2015) 1.04
The paradox of equipoise: the principle that drives and limits therapeutic discoveries in clinical research. Cancer Control (2009) 1.04
Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. Neurology (2015) 1.01
Exploratory study of web-based planning and mobile text reminders in an overweight population. J Med Internet Res (2011) 1.01
Structural and functional brain rewiring clarifies preserved interhemispheric transfer in humans born without the corpus callosum. Proc Natl Acad Sci U S A (2014) 1.01
Tailored lighting intervention improves measures of sleep, depression, and agitation in persons with Alzheimer's disease and related dementia living in long-term care facilities. Clin Interv Aging (2014) 1.01
Brake response time before and after total knee arthroplasty: a prospective cohort study. BMC Musculoskelet Disord (2010) 1.00
Informed consent for research obtained during the intensive care unit stay. Crit Care (2006) 1.00
Initial impact and cost of a nationwide population screening campaign for diabetes in Brazil: a follow up study. BMC Health Serv Res (2008) 1.00
Effect of exenatide on the pharmacokinetics of a combination oral contraceptive in healthy women: an open-label, randomised, crossover trial. BMC Clin Pharmacol (2012) 1.00
Identification of genetic variants influencing the human plasma proteome. Proc Natl Acad Sci U S A (2013) 1.00
Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults. Int J Obes (Lond) (2013) 0.98
The association of early post-transplant glucose levels with long-term mortality. Diabetologia (2011) 0.98
Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. Nat Commun (2014) 0.97
Ethical and legal issues in pain research in cognitively impaired older adults. Int J Nurs Stud (2012) 0.97
An Open-Label, Noncomparative, Multicenter Study to Evaluate Efficacy and Safety of NASHA/Dx Gel as a Bulking Agent for the Treatment of Fecal Incontinence. Gastroenterol Res Pract (2010) 0.97
Microbicides development programme: engaging the community in the standard of care debate in a vaginal microbicide trial in Mwanza, Tanzania. BMC Med Ethics (2009) 0.96
How public home care officers reason when making a needs assessment for food distribution to homebound elderly persons in Sweden. Glob J Health Sci (2013) 0.96
Exercise addiction in Spanish athletes: Investigation of the roles of gender, social context and level of involvement. J Behav Addict (2013) 0.95
Acupuncture trials and informed consent. J Med Ethics (2007) 0.95
Feasibility and effectiveness of inhaled carboplatin in NSCLC patients. Invest New Drugs (2011) 0.95
Efficacy and safety of fluticasone furoate 100 μg and 200 μg once daily in the treatment of moderate-severe asthma in adults and adolescents: a 24-week randomised study. BMC Pulm Med (2014) 0.95
Intensity-modulated stereotactic body radiotherapy for stage I non-small cell lung cancer. Oncol Lett (2012) 0.95
Family Peer Advocates: A Pilot Study of the Content and Process of Service Provision. J Child Fam Stud (2011) 0.94
The Quality Initiative in Rectal Cancer (QIRC) trial: study protocol of a cluster randomized controlled trial in surgery. BMC Surg (2008) 0.93
Are there adverse consequences of quizzing during informed consent for HIV research? J Med Ethics (2011) 0.93
Cytokine factors present in dengue patient sera induces alterations of junctional proteins in human endothelial cells. Am J Trop Med Hyg (2012) 0.93
Napsin A as a marker of clear cell ovarian carcinoma. BMC Cancer (2013) 0.92
The modified ampullar approach for vestibular implant surgery: feasibility and its first application in a human with a long-term vestibular loss. Front Neurol (2012) 0.92
Socioeconomic determinants of mortality in HIV: evidence from a clinical cohort in Uganda. J Acquir Immune Defic Syndr (2014) 0.91
An open future for ecological and evolutionary data? BMC Ecol (2014) 0.91
Randomised placebo-controlled study of the effect of paracetamol on asthma severity in adults. BMJ Open (2014) 0.91
The EVIDENT-trial: protocol and rationale of a multicenter randomized controlled trial testing the effectiveness of an online-based psychological intervention. BMC Psychiatry (2013) 0.91
Early Parasympathetic Reinnervation Is Not Related to Reconnection of Major Branches of the Vagus Nerve after Heart Transplantation. Korean Circ J (2016) 0.91
Rationale and clinical benefits of an intensive long-term pulmonary rehabilitation program after oesophagectomy: preliminary report. Multidiscip Respir Med (2012) 0.90
High body mass index is an important risk factor for the development of type 2 diabetes. Intern Med (2012) 0.90
The ethics of using innovative therapies in the care of children. Paediatr Child Health (2008) 0.90
Returning individual research results for genome sequences of pancreatic cancer. Genome Med (2014) 0.90
Interaction of hope and optimism with anxiety and depression in a specific group of cancer survivors: a preliminary study. BMC Res Notes (2011) 0.90