Published in Gastroenterology on February 01, 1975
Clinical pathologic correlation in viral hepatitis. The effect of the virus on the liver. Am J Pathol (1975) 1.50
Inter-subject and ethnic differences in paracetamol metabolism. Br J Clin Pharmacol (1986) 1.48
Antigens of the human liver. Clin Exp Immunol (1980) 1.25
Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress. J Clin Invest (1984) 1.18
A new antimitochondria antibody (anti-M6) in iproniazid-induced hepatitis. Clin Exp Immunol (1982) 1.17
Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis. Am J Pathol (1985) 1.00
Characteristics of cytochrome P-450 and mixed function oxidase enzymes following treatment with PBBs. Environ Health Perspect (1978) 0.98
The role of biotransformation in chemical-induced liver injury. Environ Health Perspect (1976) 0.98
A comparative study of the formation of chemically reactive drug metabolites by human liver microsomes. Br J Clin Pharmacol (1988) 0.94
High incidence of a concentration-dependent skin reaction in children treated with phenytoin. Br Med J (1978) 0.88
Evaluation of isoniazid-associated hepatitis by immunological tests. Clin Exp Immunol (1978) 0.88
Hepatic reactions to drugs. Gut (1979) 0.85
Heterogeneity in the rate of benzo[a]pyrene metabolism in single cells: quantitation using flow cytometry. Mol Cell Biol (1982) 0.85
Nitrofurantoin cytotoxicity. In vitro assessment of risk based on glutathione metabolism. J Clin Invest (1981) 0.84
Inhibition of the metabolism of paracetamol by isoniazid. Br J Clin Pharmacol (1991) 0.84
Interaction of alcohol with other drugs and nutrients. Implication for the therapy of alcoholic liver disease. Drugs (1990) 0.77
Drug-induced acute liver disease. Postgrad Med J (1989) 0.75
Histological, molecular and biochemical detection of renal injury after Echis pyramidum snake envenomation in rats. Saudi J Biol Sci (2014) 0.75
Interplay of factors leading to adverse drug reactions in the liver, a personal viewpoint. Yale J Biol Med (1978) 0.75
Medical Staff Conference. Drug-induced liver disease. West J Med (1979) 0.75
Lymphocyte-mediated cytotoxicity in isoniazid-associated hepatitis. Clin Exp Immunol (1979) 0.75
Relative contributions of history-taking, physical examination, and laboratory investigation to diagnosis and management of medical outpatients. Br Med J (1975) 9.18
Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther (1973) 5.23
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. J Pharmacol Exp Ther (1973) 4.40
Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology (1974) 4.32
A randomised trial of home-versus-hospital management for patients with suspected myocardial infarction. Lancet (1978) 4.12
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. J Pharmacol Exp Ther (1973) 3.89
Interim discharge summaries: how are they best delivered to general practitioners? Br Med J (Clin Res Ed) (1987) 3.64
Menopausal flushing: does oestrogen therapy make sense? Lancet (1976) 3.47
Self-poisoning: management of patients in Nottingham, 1976. Br Med J (1978) 3.24
Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy. Clin Pharmacol Ther (1974) 2.62
Accumulation and elimination of poliovirus by the eastern oyster. Am J Epidemiol (1966) 2.58
Randomised placebo-controlled trial comparing oxprenolol with disopyramide phosphate in immediate treatment of suspected myocardial infarction. Lancet (1980) 2.53
Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis. Ann Intern Med (1976) 2.33
Randomised trial comparing propranolol with atenolol in immediate treatment of suspected myocardial infarction. Br Med J (1980) 2.32
Guanethidine and related agents. 3. Antagonism by drugs which inhibit the norepinephrine pump in man. J Clin Invest (1970) 2.29
RNA binding domain of telomerase reverse transcriptase. Mol Cell Biol (2001) 2.27
Effect of a pyrimidopyrimidine derivative on thrombus formation in the rabbit. Nature (1965) 2.19
Is nursing any business of doctors? A simple guide to the "nursing process". Br Med J (Clin Res Ed) (1984) 2.17
Early reporting of myocardial infarction: impact of an experiment in patient education. Br Med J (Clin Res Ed) (1982) 2.11
Isoniazid-associated hepatitis in 114 patients. Gastroenterology (1975) 2.02
Platelet reactivity and serum thromboxane B2 production in whole blood in gestational hypertension and pre-eclampsia. Br J Obstet Gynaecol (1991) 1.91
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro. J Pharmacol Exp Ther (1973) 1.90
Effect of prostaglandin E1 on platelet behaviour in vitro and in vivo. Br Med J (1967) 1.85
Extracts of feverfew inhibit granule secretion in blood platelets and polymorphonuclear leucocytes. Lancet (1985) 1.84
An association between abo blood-group distribution and geographical differences in death-rates. Lancet (1977) 1.81
Effect of dipyridamole on human platelet behaviour. Lancet (1965) 1.79
Plasma glutathione and glutathione disulfide in the rat: regulation and response to oxidative stress. J Pharmacol Exp Ther (1983) 1.79
Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydranize metabolites. Clin Pharmacol Ther (1975) 1.75
Oxidation of alpha-methyldopa and other catechols by cytochrome P-450-generated superoxide anion: possible mechanism of methyldopa hepatitis. Mol Pharmacol (1976) 1.73
Dexamethasone in acute stroke. Br Med J (1978) 1.73
Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacology (1974) 1.70
Is an information booklet for patients leaving hospital helpful and useful? BMJ (1989) 1.68
Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA (1967) 1.67
What constitutes evidence on the dietary prevention of coronary heart disease? Cosy beliefs or harsh facts? Int J Cardiol (1984) 1.66
Randomised double-blind placebo-controlled trial of feverfew in migraine prevention. Lancet (1988) 1.62
The role of the interview in student selection. S Afr Med J (1978) 1.59
Autumn Books: Who needs Clinical Pharmacology? Br Med J (Clin Res Ed) (1984) 1.57
"But will it help my patients with myocardial infarction?" The implications of recent trials for everyday country folk. Br Med J (Clin Res Ed) (1982) 1.55
Effect of aggregating agents on the electrophoretic mobility of human platelets. Br Med J (1966) 1.55
Prevention and diagnosis of venous thrombosis in patients with hip fractures. A survey of current practice. Lancet (1976) 1.52
Blood pressure reduction in elderly: a randomised controlled trial of methyldopa. Br Med J (Clin Res Ed) (1981) 1.52
Effect of oestrogens on human platelet behaviour. Lancet (1968) 1.49
Low dose beta blockade in acute stroke ("BEST" trial): an evaluation. Br Med J (Clin Res Ed) (1988) 1.47
Use of isolated perfused organs in hypoxia and ischemia/reperfusion oxidant stress. Methods Enzymol (1990) 1.46
Patients' and general practitioners' satisfaction with information given on discharge from hospital: audit of a new information card. BMJ (1989) 1.45
Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters. Pharmacology (1974) 1.43
Reactive oxygen species during ischemia-reflow injury in isolated perfused rat liver. J Clin Invest (1988) 1.38
Parent and peer attachment in early adolescent depression. J Abnorm Child Psychol (1990) 1.38
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat. Science (1976) 1.38
Magnetization transfer and multicomponent T2 relaxation measurements with histopathologic correlation in an experimental model of MS. J Magn Reson Imaging (2000) 1.37
Anticoagulants in coronary heart disease--retrospect and prospect. Lancet (1981) 1.36
Platelet behaviour and drugs used in cardiovascular disease. Cardiovasc Res (1967) 1.32
Abnormalities in platelet behaviour in acute illnesses. Br Med J (1966) 1.31
Treatment of high blood pressure: should clinical practice be based on results of clinical trials? Br Med J (Clin Res Ed) (1986) 1.31
Mechanism of action of N-acetylcysteine in the protection against the hepatotoxicity of acetaminophen in rats in vivo. J Clin Invest (1983) 1.31
Nature of the transferable factor which causes abnormal platelet behaviour in vascular disease. Lancet (1967) 1.27
Clinical management of venous thrombo-embolism. Br Med Bull (1978) 1.26
Contribution of atenolol, bendrofluazide, and hydrallazine to management of severe hypertension. Br Med J (1977) 1.26
Organisation of the external region of the starch granule as determined by infrared spectroscopy. Int J Biol Macromol (2002) 1.26
Guanethidine and related agents. I. Mechanism of the selective blockade of adrenergic neurons and its antagonism by drugs. J Pharmacol Exp Ther (1970) 1.26
Timolol after myocardial infarction: an answer or a new set of questions? Br Med J (Clin Res Ed) (1981) 1.25
Pilot studies on recombinant cold-adapted live type A and B influenza virus vaccines. J Infect Dis (1977) 1.25
Platelet aggregation in whole blood determined using the Ultra-Flo 100 Platelet Counter. Thromb Haemost (1982) 1.25
Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice. J Pharmacol Exp Ther (1985) 1.24
Hepatic glutathione homeostasis in the rat: efflux accounts for glutathione turnover. Hepatology (1984) 1.23
Developments in understanding the basis of cooked-rice texture. Crit Rev Food Sci Nutr (2000) 1.23
Effect of oral contraceptive agents on platelets and plasma-phospholipids. Lancet (1968) 1.23
Oestrogen treatment for menopausal flushing. Br Med J (1977) 1.21
The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study. Mult Scler (2007) 1.18
Acute pulmonary injury in rats by nitrofurantoin and modification by vitamin E, dietary fat, and oxygen. Am Rev Respir Dis (1979) 1.18
Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress. J Clin Invest (1984) 1.18
Molecular basis for several drug-induced nephropathies. Am J Med (1977) 1.18
Impact of particle size distribution on rheological and textural properties of chocolate models with reduced fat content. J Food Sci (2007) 1.18
Neonatal platelet reactivity and serum thromboxane B2 production in whole blood: the effect of maternal low dose aspirin. Br J Obstet Gynaecol (1994) 1.18
Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine. Mol Pharmacol (1980) 1.18
Secondary prevention of myocardial infarction--the present state of the ART. Br Med J (1980) 1.16
Intravenous urography in the management of acute retention. Lancet (1977) 1.16
Effectiveness of speech therapy for aphasic stroke patients. A randomised controlled trial. Lancet (1984) 1.16
Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals. Diabetes (2001) 1.15
Effect of glass contact on the electrophoretic mobility of human blood platelets. Nature (1966) 1.14
The variability of human platelet aggregation. J Atheroscler Res (1967) 1.13
A placebo-controlled dose-response study of the reactogenicity and immunogenicity of a cold-adapted recombinant A/Victoria/3/75 (H3N2) live influenza virus candidate vaccine in healthy volunteers. Dev Biol Stand (1978) 1.13
Acetylation rates and monthly liver function tests during one year of isoniazid preventive therapy. Chest (1975) 1.12
Preventing venous thromboembolism in elderly patients with hip fractures: studies of low-dose heparin, dipyridamole, aspirin, and flurbiprofen. Br Med J (1977) 1.10
The influence of psychosocial factors on survival after myocardial infarction. Public Health (1993) 1.10
The influence of red blood-cells on platelet adhesiveness. Lancet (1966) 1.09
An investigation of the cause of accumulation of verapamil during regular dosing in patients. Br J Clin Pharmacol (1985) 1.08
The pragmatic approach to stroke trial design: stroke register, pilot trial, assessment of neurological then functional outcome. Neuroepidemiology (1988) 1.07
Regulation of hepatic glutathione turnover in rats in vivo and evidence for kinetic homogeneity of the hepatic glutathione pool. J Clin Invest (1981) 1.07
Hyperimmunoglobulinaemia D and periodic fever. Lancet (1984) 1.07
Enzyme-linked immunosorbent assay with major outer membrane proteins of Brucella melitensis to measure immune response to Brucella species. J Clin Microbiol (1986) 1.07
Warfarin sodium in prevention of deep venous thrombosis and pulmonary embolism in patients with fractured neck of femur. Lancet (1976) 1.07
Mitochondria and xanthine oxidase both generate reactive oxygen species in isolated perfused rat liver after hypoxic injury. Biochem Biophys Res Commun (1989) 1.06
Therapeutic doses of acetaminophen stimulate the turnover of cysteine and glutathione in man. J Hepatol (1987) 1.06
Predicting the outcome of acute stroke: do multivariate models help? Q J Med (1989) 1.03
Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen. Life Sci (1974) 1.02
Clinical events resulting from thrombus formation. Br Med Bull (1978) 1.02
Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo. J Pharmacol Exp Ther (1980) 1.01
T2 MRI texture analysis is a sensitive measure of tissue injury and recovery resulting from acute inflammatory lesions in multiple sclerosis. Neuroimage (2009) 1.01
Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein. J Lipid Res (1990) 1.01