Published in J Virol on May 01, 2001
A structural and functional perspective of alphavirus replication and assembly. Future Microbiol (2009) 1.72
Capsid protein C of tick-borne encephalitis virus tolerates large internal deletions and is a favorable target for attenuation of virulence. J Virol (2002) 1.48
Alphavirus capsid protein helix I controls a checkpoint in nucleocapsid core assembly. J Virol (2006) 1.01
Role of sindbis virus capsid protein region II in nucleocapsid core assembly and encapsidation of genomic RNA. J Virol (2008) 0.98
Molecular links between the E2 envelope glycoprotein and nucleocapsid core in Sindbis virus. J Mol Biol (2011) 0.98
Imaging of the alphavirus capsid protein during virus replication. J Virol (2013) 0.88
Rescue of infectious particles from preassembled alphavirus nucleocapsid cores. J Virol (2011) 0.87
Imaging the alphavirus exit pathway. J Virol (2014) 0.86
An alphavirus temperature-sensitive capsid mutant reveals stages of nucleocapsid assembly. Virology (2015) 0.75
The alphaviruses: gene expression, replication, and evolution. Microbiol Rev (1994) 16.68
Nucleotide sequence of cdna coding for Semliki Forest virus membrane glycoproteins. Nature (1980) 8.07
In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6,000-molecular-weight membrane protein modulates virus release. J Virol (1991) 6.02
The T=4 envelope of Sindbis virus is organized by interactions with a complementary T=3 capsid. Cell (1987) 5.99
Nucleocapsid and glycoprotein organization in an enveloped virus. Cell (1995) 3.66
The heterodimeric association between the membrane proteins of Semliki Forest virus changes its sensitivity to low pH during virus maturation. J Virol (1989) 3.09
Spike protein-nucleocapsid interactions drive the budding of alphaviruses. J Virol (1992) 2.91
Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly. Structure (1996) 2.46
Cryo-electron microscopy reveals the functional organization of an enveloped virus, Semliki Forest virus. Mol Cell (2000) 2.28
Membrane fusion process of Semliki Forest virus. II: Cleavage-dependent reorganization of the spike protein complex controls virus entry. J Cell Biol (1992) 2.26
Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Biotechnology (N Y) (1993) 2.20
Sequence analysis of three Sindbis virus mutants temperature-sensitive in the capsid protein autoprotease. Proc Natl Acad Sci U S A (1985) 2.18
Internally located cleavable signal sequences direct the formation of Semliki Forest virus membrane proteins from a polyprotein precursor. J Virol (1991) 2.17
Site-directed mutations in Sindbis virus E2 glycoprotein's cytoplasmic domain and the 6K protein lead to similar defects in virus assembly and budding. Virology (1991) 2.14
Aromatic interactions define the binding of the alphavirus spike to its nucleocapsid. Structure (1996) 2.12
A tyrosine-based motif in the cytoplasmic domain of the alphavirus envelope protein is essential for budding. EMBO J (1994) 2.09
Processing of the Semliki Forest virus structural polyprotein: role of the capsid protease. J Virol (1987) 1.96
Membrane proteins organize a symmetrical virus. EMBO J (2000) 1.67
Site-directed mutations in the Sindbis virus 6K protein reveal sites for fatty acylation and the underacylated protein affects virus release and virion structure. Virology (1990) 1.61
Alphavirus budding is dependent on the interaction between the nucleocapsid and hydrophobic amino acids on the cytoplasmic domain of the E2 envelope glycoprotein. Virology (1997) 1.61
In vitro assembly of alphavirus cores by using nucleocapsid protein expressed in Escherichia coli. J Virol (1999) 1.54
The signal sequence of the p62 protein of Semliki Forest virus is involved in initiation but not in completing chain translocation. J Cell Biol (1990) 1.38
Nucleic acid-dependent cross-linking of the nucleocapsid protein of Sindbis virus. J Virol (2000) 1.25
Preformed cytoplasmic nucleocapsids are not necessary for alphavirus budding. EMBO J (1996) 1.19
Evidence for a change in capsid morphology during Sindbis virus envelopment. Virus Res (1984) 1.18
Transient association of Semliki Forest virus capsid protein with ribosomes. J Virol (1977) 1.08
Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building. Proteins (1998) 0.96
Role of the C-terminal tryptophan residue for the structure-function of the alphavirus capsid protein. J Mol Biol (1998) 0.91
A conserved leucine in the cytoplasmic domain of the Semliki Forest virus spike protein is important for budding. Arch Virol (2000) 0.84
Assembly of Semliki Forest virus nucleocapsid: detection of a precursor in infected cells. J Gen Virol (1978) 0.83
Spike protein-nucleocapsid interactions drive the budding of alphaviruses. J Virol (1992) 2.91
Membrane fusion process of Semliki Forest virus. II: Cleavage-dependent reorganization of the spike protein complex controls virus entry. J Cell Biol (1992) 2.26
Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Biotechnology (N Y) (1993) 2.20
Enhancing immune responses using suicidal DNA vaccines. Nat Biotechnol (1998) 2.20
Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine. J Virol (1996) 2.12
Aromatic interactions define the binding of the alphavirus spike to its nucleocapsid. Structure (1996) 2.12
A tyrosine-based motif in the cytoplasmic domain of the alphavirus envelope protein is essential for budding. EMBO J (1994) 2.09
Nuclear localization of Semliki Forest virus-specific nonstructural protein nsP2. J Virol (1990) 1.99
Cosmid cloning and transposon mutagenesis in Salmonella typhimurium using phage lambda vehicles. Mol Gen Genet (1981) 1.80
Two-helper RNA system for production of recombinant Semliki forest virus particles. J Virol (1999) 1.69
Assembly and entry mechanisms of Semliki Forest virus. Arch Virol Suppl (1994) 1.42
The signal sequence of the p62 protein of Semliki Forest virus is involved in initiation but not in completing chain translocation. J Cell Biol (1990) 1.38
Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3/4A gene. Gene Ther (2004) 1.36
Expression of heterologous proteins in cultured rat hippocampal neurons using the Semliki Forest virus vector. J Neurosci Res (1993) 1.34
Relation between viral fitness and immune escape within the hepatitis C virus protease. Gut (2005) 1.33
Membrane protein lateral interactions control Semliki Forest virus budding. EMBO J (1994) 1.31
Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine (1994) 1.30
In vivo transfer of chromosomal mutations onto multicopy plasmids by transduction with bacteriophage P1. Gene (1985) 1.26
The 6-kilodalton membrane protein of Semliki Forest virus is involved in the budding process. J Virol (1995) 1.26
High-level expression of the human neurokinin-1 receptor in mammalian cell lines using the Semliki Forest virus expression system. Eur J Biochem (1994) 1.25
Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus. Proc Natl Acad Sci U S A (1995) 1.21
Fate of the 6K membrane protein of Semliki Forest virus during virus assembly. Virology (1991) 1.20
Nucleotide sequence of the melA gene, coding for alpha-galactosidase in Escherichia coli K-12. Nucleic Acids Res (1987) 1.18
Outcome of immunization of cynomolgus monkeys with recombinant Semliki Forest virus encoding human immunodeficiency virus type 1 envelope protein and challenge with a high dose of SHIV-4 virus. AIDS Res Hum Retroviruses (1997) 1.16
Low dose and gene gun immunization with a hepatitis C virus nonstructural (NS) 3 DNA-based vaccine containing NS4A inhibit NS3/4A-expressing tumors in vivo. Gene Ther (2003) 1.11
Cloning of the regulatory locus ompB of Salmonella typhimurium LT-2. II. Identification of the envZ gene product, a protein involved in the expression of the porin proteins. Mol Gen Genet (1982) 1.10
Expression of HIV-1 envelope glycoproteins by Semliki Forest virus vectors. AIDS Res Hum Retroviruses (1993) 1.07
Self-replicative RNA vaccines elicit protection against influenza A virus, respiratory syncytial virus, and a tickborne encephalitis virus. J Infect Dis (2001) 1.07
Alphavirus assembly and entry: role of the cytoplasmic tail of the E1 spike subunit. J Virol (1992) 1.07
Non-viral amplification systems for gene transfer: vectors based on alphaviruses. Curr Opin Mol Ther (1999) 1.07
Plasminogen-activator inhibitor type 2 (PAI-2) is a spontaneously polymerising SERPIN. Biochemical characterisation of the recombinant intracellular and extracellular forms. Eur J Biochem (1993) 1.04
The molecular pathogenesis of Semliki Forest virus: a model virus made useful? J Gen Virol (1999) 1.02
The efficiency of the uncleaved secretion signal in the plasminogen activator inhibitor type 2 protein can be enhanced by point mutations that increase its hydrophobicity. J Biol Chem (1991) 0.99
Alphavirus expression vectors and their use as recombinant vaccines: a minireview. Gene (1997) 0.99
Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice. Vaccine (1999) 0.99
Two mutations in the envelope glycoprotein E2 of Semliki Forest virus affecting the maturation and entry patterns of the virus alter pathogenicity for mice. Virology (1991) 0.98
A single amino acid change in the E2 spike protein of a virulent strain of Semliki Forest virus attenuates pathogenicity. J Gen Virol (1994) 0.94
Budding of enveloped viruses from the plasma membrane. Bioessays (1997) 0.93
Isolation and characterization of a substitution mutation in the ompR gene of Salmonella typhimurium LT2. J Bacteriol (1987) 0.91
Role of the C-terminal tryptophan residue for the structure-function of the alphavirus capsid protein. J Mol Biol (1998) 0.91
Expression of exogenous proteins in mammalian cells with the Semliki Forest virus vector. Methods Cell Biol (1994) 0.90
Suppressors of cleavage-site mutations in the p62 envelope protein of Semliki Forest virus reveal dynamics in spike structure and function. J Virol (1998) 0.88
Induction of P815 tumor immunity by recombinant Semliki Forest virus expressing the P1A gene. Gene Ther (1999) 0.88
Protection against respiratory syncytial virus (RSV) elicited in mice by plasmid DNA immunisation encoding a secreted RSV G protein-derived antigen. FEMS Immunol Med Microbiol (2000) 0.88
Recombinant Semliki Forest virus particles encoding the prME or NS1 proteins of louping ill virus protect mice from lethal challenge. J Gen Virol (1999) 0.87
Cloning of the regulatory locus ompB of Salmonella typhimurium LT-2. I. Isolation of the ompR gene and identification of its gene product. Mol Gen Genet (1982) 0.86
A conserved leucine in the cytoplasmic domain of the Semliki Forest virus spike protein is important for budding. Arch Virol (2000) 0.84
Recombinant Semliki Forest virus particles expressing louping ill virus antigens induce a better protective response than plasmid-based DNA vaccines or an inactivated whole particle vaccine. J Gen Virol (2000) 0.83
A recombinant Semliki Forest virus particle vaccine encoding the prME and NS1 proteins of louping ill virus is effective in a sheep challenge model. Vaccine (2001) 0.83
Semliki Forest virus-based vaccines: persistence, distribution and pathological analysis in two animal systems. Vaccine (2001) 0.82
Alphaviruses as vectors for gene delivery. Trends Biotechnol (1996) 0.82
Manipulation of the Semliki Forest virus genome and its potential for vaccine construction. Mol Biotechnol (1996) 0.81
Hepatitis C virus non-structural protein 3-specific cellular immune responses following single or combined immunization with DNA or recombinant Semliki Forest virus particles. J Gen Virol (2002) 0.80
Cloning of human IL-12 p40 and p35 DNA into the Semliki Forest virus vector: expression of IL-12 in human tumor cells. Gene Ther (1997) 0.77
Comparative immunization study using RNA and DNA constructs encoding a part of the Plasmodium falciparum antigen Pf332. Scand J Immunol (2001) 0.77
Recombinant Semliki Forest virus vaccine vectors: the route of injection determines the localization of vector RNA and subsequent T cell response. Gene Ther (2001) 0.77
A vaccine strategy utilizing a combination of three different chimeric vectors which share specific vaccine antigens. J Med Primatol (2000) 0.77
The SFV Gene Expression System. Methods Mol Med (1998) 0.75