Clinical applications of phage-derived sFvs and sFv fusion proteins.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 3851051)

Published in Dis Markers on January 01, 2000

Authors

K A Chester1, J Bhatia, G Boxer, S P Cooke, A A Flynn, A Huhalov, A Mayer, R B Pedley, L Robson, S K Sharma, D I Spencer, R H Begent

Author Affiliations

1: CRC Targeting & Imaging Group, Department of Oncology, Royal Free & University College Medical School, UCL, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK. kac@rfhsm.ac.uk

Articles by these authors

Replicating SV40 molecules containing closed circular template DNA strands. Nat New Biol (1971) 4.36

Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion. Nature (2001) 4.10

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol Cell Biol (1996) 3.50

Ca2+/calmodulin signals the completion of docking and triggers a late step of vacuole fusion. Nature (1998) 3.33

Relationship between tumour size and uptake of radiolabelled anti-CEA in a colon tumour xenograft. Eur J Nucl Med (1987) 3.16

Morphine receptors as regulators of adenylate cyclase activity. Proc Natl Acad Sci U S A (1975) 3.10

Body-mass index, waist-size, waist-hip ratio and cardiovascular risk factors in urban subejcts. J Assoc Physicians India (2007) 2.87

Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance. Proc Natl Acad Sci U S A (1975) 2.71

Molecular characterization of multidrug-resistant isolates of Mycobacterium tuberculosis from patients in North India. Antimicrob Agents Chemother (2002) 2.59

Comparison of in house polymerase chain reaction with conventional techniques for the detection of Mycobacterium tuberculosis DNA in granulomatous lymphadenopathy. J Clin Pathol (2000) 2.32

Randomized trial of epidural versus intravenous analgesia during labor. Obstet Gynecol (1995) 2.30

Noninvasive in vivo human coronary artery lumen and wall imaging using black-blood magnetic resonance imaging. Circulation (2000) 2.29

Cutaneous manifestation of diabetes mellitus. Indian J Dermatol Venereol Leprol (2007) 2.16

Dual human immunodeficiency virus type 1 infection and recombination in a dually exposed transfusion recipient. The Transfusion Safety Study Group. J Virol (1995) 2.15

Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70. J Biol Chem (1997) 2.14

In vivo high-resolution 3D photoacoustic imaging of superficial vascular anatomy. Phys Med Biol (2009) 2.10

A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene. Proc Natl Acad Sci U S A (1984) 2.07

Identification of human immunodeficiency virus type 1 envelope genes recombinant between subtypes B and F in two epidemiologically linked individuals from Brazil. J Virol (1994) 2.05

Upper gastrointestinal haemorrhage in portal hypertension. Is an emergency endoscopy necessarily required? J Assoc Physicians India (1989) 2.02

EMA/CO for high-risk gestational trophoblastic tumors: results from a cohort of 272 patients. J Clin Oncol (1997) 2.00

Prediction of response to iron sucrose in inflammatory bowel disease-associated anemia. Am J Gastroenterol (2001) 2.00

Morbidity and mortality attributable to alcohol, tobacco, and illicit drug use in Canada. Am J Public Health (1999) 1.99

Comparison of ondansetron and ondansetron plus dexamethasone as antiemetic prophylaxis during cisplatin-containing chemotherapy. Lancet (1991) 1.95

The effect of blood transfusion protocol on retinopathy of prematurity: A prospective, randomized study. Pediatrics (1999) 1.88

Nocturnal enuresis: an international evidence based management strategy. J Urol (2004) 1.85

Assessment methods for alcohol consumption, prevalence of high risk drinking and harm: a sensitivity analysis. Int J Epidemiol (1999) 1.84

Classification of non-bacterial osteitis: retrospective study of clinical, immunological and genetic aspects in 89 patients. Rheumatology (Oxford) (2006) 1.84

Nucleotide-induced stable complex formation by HIV-1 reverse transcriptase. Biochemistry (1997) 1.82

Latency versus persistence or intermittent recurrences: evidence for a latent state of murine cytomegalovirus in the lungs. J Virol (1997) 1.82

Further advances in the management of malignant teratomas of the testis and other sites. Lancet (1983) 1.80

Accurate quantification of 131I distribution by gamma camera imaging. Eur J Nucl Med (1990) 1.78

Detection of human retrovirus 5 in patients with arthritis and systemic lupus erythematosus. Arthritis Rheum (1999) 1.76

Control of the terminal step of intracellular membrane fusion by protein phosphatase 1. Science (1999) 1.75

A large cholera outbreak due to a new cholera toxin variant of the Vibrio cholerae O1 El Tor biotype in Orissa, Eastern India. J Med Microbiol (2009) 1.74

Nasal intermittent positive pressure ventilation after surfactant treatment for respiratory distress syndrome in preterm infants <30 weeks' gestation: a randomized, controlled trial. J Perinatol (2012) 1.73

Ophthalmic manifestations of HIV infections in India in the era of HAART: analysis of 100 consecutive patients evaluated at a tertiary eye care center in India. Ophthalmic Epidemiol (2008) 1.71

Primary thyroid lymphoma is a heterogeneous disease. J Clin Endocrinol Metab (2002) 1.70

The relative risks and etiologic fractions of different causes of death and disease attributable to alcohol, tobacco and illicit drug use in Canada. CMAJ (2000) 1.68

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists. Proc Natl Acad Sci U S A (1999) 1.67

Host-specific driving force in human immunodeficiency virus type 1 evolution in vivo. J Virol (1997) 1.63

Opiate-dependent modulation of adenylate cyclase. Proc Natl Acad Sci U S A (1977) 1.60

A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol (1997) 1.60

Prevalence of β-thalassemia and other haemoglobinopathies in six cities in India: a multicentre study. J Community Genet (2012) 1.58

Topographical variation in patellar subarticular calcified tissue density. J Anat (1979) 1.57

Creatine kinase-MB elevation after coronary intervention correlates with diffuse atherosclerosis, and low-to-medium level elevation has a benign clinical course: implications for early discharge after coronary intervention. J Am Coll Cardiol (1999) 1.54

Review of wheat improvement for waterlogging tolerance in Australia and India: the importance of anaerobiosis and element toxicities associated with different soils. Ann Bot (2008) 1.53

The economic costs of alcohol, tobacco and illicit drugs in Canada, 1992. Addiction (1998) 1.53

Developments in chemotherapy for medium- and high-risk patients with gestational trophoblastic tumours (1979-1984). Br J Obstet Gynaecol (1986) 1.53

DOTS at a tertiary care center in northern India: successes, challenges and the next steps in tuberculosis control. Indian J Med Res (2006) 1.53

A cytotoxic agent can be generated selectively at cancer sites. Br J Cancer (1988) 1.52

Antimicrobial utilization pattern in out patient services of ENT department of tertiary care hospital of Eastern Nepal. Kathmandu Univ Med J (KUMJ) (2006) 1.51

Skin bridge--a complication of paediatric circumcision. Br J Urol (1990) 1.50

Tumour-marker levels and prognosis in malignant teratoma of the testis. Br J Cancer (1980) 1.49

Incidence and mechanism of creatine kinase-MB enzyme elevation after coronary intervention with different devices. Catheter Cardiovasc Interv (1999) 1.49

Epidural analgesia during labor and maternal fever. Anesthesiology (1999) 1.49

Haemoptysis in patients with a normal chest radiograph: bronchoscopy-CT correlation. Australas Radiol (1999) 1.48

Current optimum management of anaplastic germ cell tumours of the testis and other sites. Br J Urol (1986) 1.48

Computerized tomography attenuation value of renal calculus: can it predict successful fragmentation of the calculus by extracorporeal shock wave lithotripsy? A preliminary study. J Urol (2002) 1.46

Final results of the Balloon vs Optimal Atherectomy Trial (BOAT) Circulation (1998) 1.45

A randomized trial of labor analgesia in women with pregnancy-induced hypertension. Am J Obstet Gynecol (2001) 1.44

Radiation dose to family members of hyperthyroidism and thyroid cancer patients treated with 131I. Radiat Prot Dosimetry (2005) 1.43

Anti-inflammatory activity of Trichodesma indicum root extract in experimental animals. J Ethnopharmacol (2005) 1.42

In vitro assessment of Lipiodol-targeted radiotherapy for liver and colorectal cancer cell lines. Br J Cancer (1999) 1.42

Chemotherapy of advanced malignant teratomas. Br J Cancer (1980) 1.40

Rotational atherectomy: improved procedural outcome with evolution of technique and equipment. Single-center results of first 1,000 patients. Catheter Cardiovasc Interv (1999) 1.40

A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes. Proc Natl Acad Sci U S A (1997) 1.40

Angiographic patterns of in-stent restenosis and implications on subsequent revascularization. Catheter Cardiovasc Interv (2000) 1.40

Plasmodium falciparum infection elicits both variant-specific and cross-reactive antibodies against variant surface antigens. Infect Immun (2003) 1.39

Can sonography replace splenoportovenography in evaluation of patients with portal hypertension? Indian J Gastroenterol (1989) 1.39

Protein growth factor(s) from C6 glioma cells that promote the growth of murine hybridomas. J Immunol Methods (1991) 1.39

Septic shock: pathogenesis and treatment. J Assoc Physicians India (1996) 1.39

Increased expression of c-myc proto-oncogene in biopsies of ulcerative colitis and Crohn's colitis. Gut (1992) 1.38

Status of iodine content of salt in four regions of India. Indian J Pediatr (2010) 1.38

Human leptin deficiency and resistance. J Assoc Physicians India (2000) 1.38

Unstable angina pectoris and non-Q-wave myocardial infarction. Heart Dis (2002) 1.37

Autophagic tubes: vacuolar invaginations involved in lateral membrane sorting and inverse vesicle budding. J Cell Biol (2000) 1.37

Pharmacokinetics of vancomycin in critically ill infants undergoing extracorporeal membrane oxygenation. Antimicrob Agents Chemother (1996) 1.36

Distribution of the Ca (Oxford) antigen in lung neoplasms and non-neoplastic lung tissues. J Clin Pathol (1984) 1.35

Cyto-protective and immunomodulating properties of Amla (Emblica officinalis) on lymphocytes: an in-vitro study. J Ethnopharmacol (2002) 1.35

The role of low-dose methotrexate and folinic acid in gestational trophoblastic tumours (GTT). Br J Obstet Gynaecol (1989) 1.35

Characterization of immune complexes in serum by adsorption on staphylococcal protein A: model studies and application to sera of rats bearing a gross virus-induced lymphoma. J Immunol (1978) 1.33

Survival in epithelial ovarian cancer: a multivariate analysis incorporating BRCA mutation status and platinum sensitivity. Ann Oncol (2010) 1.31

Cdc42p functions at the docking stage of yeast vacuole membrane fusion. EMBO J (2001) 1.31

Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques. Proc Natl Acad Sci U S A (1990) 1.31

Central nervous system metastases of choriocarcinoma. 23 years' experience at Charing Cross Hospital. Cancer (1983) 1.31

Risk of exposure to Chagas' disease among seroreactive Brazilian blood donors. Transfusion (1996) 1.30

An investigation of radiological, clinical and pathological correlations in osteoarthrosis of the hip. Clin Radiol (1980) 1.28

Phospholipid composition of highly purified mitochondrial outer membranes of rat liver and Neurospora crassa. Is cardiolipin present in the mitochondrial outer membrane? Biochim Biophys Acta (1997) 1.28

Analysis of acidic and basic chitinases from tobacco and petunia and their constitutive expression in transgenic tobacco. Mol Plant Microbe Interact (1991) 1.28

Arterolane, a new synthetic trioxolane for treatment of uncomplicated Plasmodium falciparum malaria: a phase II, multicenter, randomized, dose-finding clinical trial. Clin Infect Dis (2010) 1.27

Evaluation of anti-pyretic and analgesic activity of Emblica officinalis Gaertn. J Ethnopharmacol (2004) 1.26

Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library. Nat Med (1996) 1.24

Improved tumor targeting with chemically cross-linked recombinant antibody fragments. Cancer Res (1994) 1.24

Low efficacy of chloroquine: time to switchover to artemisinin-based combination therapy for falciparum malaria in India. Acta Trop (2009) 1.23

Dopamine and senescence in Drosophila melanogaster. Neurobiol Aging (2000) 1.23

Fv-1 regulation of lymphoma development and of thymic ecotropic and xenotropic MuLV expression in mice of the AKR/J x RF/J cross. Cell (1978) 1.22

Interleukin-6-mediated autocrine growth promotion in human glioblastoma multiforme cell line U87MG. J Neurochem (1998) 1.22

cis and trans sites of the TOM complex of mitochondria in unfolding and initial translocation of preproteins. J Biol Chem (1998) 1.21

Implications of a sex difference in osteoarthrosis. Ann Rheum Dis (1980) 1.21