Published in Crit Care Med on April 01, 2001
Glucose variability and mortality in patients with sepsis. Crit Care Med (2008) 3.00
How does blood glucose control with insulin save lives in intensive care? J Clin Invest (2004) 2.65
Experimental endotoxemia induces adipose inflammation and insulin resistance in humans. Diabetes (2009) 2.27
Intensive insulin therapy protects the endothelium of critically ill patients. J Clin Invest (2005) 2.11
Gene profiling of human adipose tissue during evoked inflammation in vivo. Diabetes (2009) 1.34
Adipose inflammation, insulin resistance, and cardiovascular disease. JPEN J Parenter Enteral Nutr (2008) 1.25
Acute insulin resistance following injury. Trends Endocrinol Metab (2009) 1.20
Bench-to-bedside review: Glucose and stress conditions in the intensive care unit. Crit Care (2010) 1.16
Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. Biochim Biophys Acta (2011) 1.05
Hyperglycemia in critical illness: a review. J Diabetes Sci Technol (2009) 1.04
Adipose genes down-regulated during experimental endotoxemia are also suppressed in obesity. J Clin Endocrinol Metab (2012) 0.85
Intensive insulin treatment improves forearm blood flow in critically ill patients: a randomized parallel design clinical trial. Crit Care (2009) 0.82
Insulin signaling in skeletal muscle and liver of neonatal pigs during endotoxemia. Pediatr Res (2008) 0.81
Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes. Endocrinology (2010) 0.81
Molecular biology: a timely tool for further unraveling the "diabetes of stress". Crit Care Med (2001) 0.78
Regulation of hepatic insulin receptor activity following injury. Am J Physiol Gastrointest Liver Physiol (2014) 0.75
Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer (2002) 5.83
Perspectives on the basic reproductive ratio. J R Soc Interface (2005) 5.34
The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem (2001) 4.74
Value-based pathology: a cost-benefit analysis of the examination of routine and nonroutine tonsil and adenoid specimens. Am J Clin Pathol (1997) 4.51
Stress-induced hyperglycemia. Crit Care Clin (2001) 3.91
Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. J Pharmacol Exp Ther (1990) 3.55
Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23. Am J Hum Genet (2000) 3.48
Prevalence of malnutrition in general medical patients. JAMA (1976) 2.95
Nonsyndromic hearing impairment: unparalleled heterogeneity. Am J Hum Genet (1997) 2.82
The gut: a central organ after surgical stress. Surgery (1988) 2.76
Early postoperative glucose control predicts nosocomial infection rate in diabetic patients. JPEN J Parenter Enteral Nutr (1998) 2.74
Epidemiology of contralateral breast cancer. Cancer Epidemiol Biomarkers Prev (1999) 2.74
Protein status of general surgical patients. JAMA (1974) 2.66
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J Clin Invest (1995) 2.66
Hemodialysis versus peritoneal dialysis: a comparison of adjusted mortality rates. Am J Kidney Dis (1997) 2.63
Carrier rates in the midwestern United States for GJB2 mutations causing inherited deafness. JAMA (1999) 2.56
Mutations in the human alpha-tectorin gene cause autosomal dominant non-syndromic hearing impairment. Nat Genet (1998) 2.52
Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F. Hum Mol Genet (2001) 2.48
Increasing thyroid cancer incidence in Canada, 1970-1996: time trends and age-period-cohort effects. Br J Cancer (2001) 2.36
Nutritional and metabolic assessment of the hospitalized patient. JPEN J Parenter Enteral Nutr (1977) 2.36
Postoperative fluid overload: not a benign problem. Crit Care Med (1990) 2.35
Congenital cytomegalovirus infection. N Engl J Med (1977) 2.35
Broadband observations of the naked-eye gamma-ray burst GRB 080319B. Nature (2008) 2.16
Farming and prostate cancer mortality. Am J Epidemiol (1993) 2.10
A re-examination of risk estimates from the NIOSH Occupational Noise and Hearing Survey (ONHS) J Acoust Soc Am (1997) 2.09
Congenital cytomegalovirus infection: diagnostic and prognostic significance of the detection of specific immunoglobulin M antibodies in cord serum. Pediatrics (1982) 2.07
Mechanism of action of camptothecin. Ann N Y Acad Sci (2000) 2.01
Mortality study of Canadian male farm operators: non-Hodgkin's lymphoma mortality and agricultural practices in Saskatchewan. J Natl Cancer Inst (1990) 2.00
Oral challenge tests for urticaria--an ethical dilemma. Br J Dermatol (1994) 1.98
Transcriptional adaptor and histone acetyltransferase proteins in Arabidopsis and their interactions with CBF1, a transcriptional activator involved in cold-regulated gene expression. Nucleic Acids Res (2001) 1.96
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med (2001) 1.95
Pattern formation in the blue-green alga, Anabaena. I. Basic mechanisms. J Cell Sci (1973) 1.92
Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1. J Biol Chem (2000) 1.91
Metabolic imaging of malignant pleural mesothelioma with fluorodeoxyglucose positron emission tomography. Chest (1998) 1.91
Prostate cancer trends in Canada: rising incidence or increased detection? CMAJ (1993) 1.91
Camptodactyly and simialr atraumatic flexion deformities of the proximal interphalangeal joints of the fingers. A study of thirty-one cases. J Bone Joint Surg Am (1968) 1.89
Genetic dissection of autoimmune type I diabetes in the BB rat. Nat Genet (1992) 1.87
Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13). Nat Genet (1999) 1.82
Eye signs in craniopharyngioma. Br J Ophthalmol (1975) 1.80
Hypocaloric total parenteral nutrition: effectiveness in prevention of hyperglycemia and infectious complications--a randomized clinical trial. Crit Care Med (2000) 1.79
Host defenses and susceptibility to infection in patients with diabetes mellitus. Infect Dis Clin North Am (1995) 1.79
Pattern formation in the blue-green alga Anabaena. II. Controlled proheterocyst regression. J Cell Sci (1973) 1.78
Recurrent meningitis and Mondini dysplasia. Arch Otolaryngol Head Neck Surg (1990) 1.77
Pendred syndrome, DFNB4, and PDS/SLC26A4 identification of eight novel mutations and possible genotype-phenotype correlations. Hum Mutat (2001) 1.77
Genomic structure and identification of novel mutations in usherin, the gene responsible for Usher syndrome type IIa. Am J Hum Genet (2000) 1.76
Trends in childhood injury mortality in Canada, 1979-2002. Inj Prev (2006) 1.73
Glutamine metabolism by the intestinal tract. JPEN J Parenter Enteral Nutr (1985) 1.71
Teratogenicity of 2-ethoxyethanol by dermal application. Drug Chem Toxicol (1982) 1.70
Localization of the Usher syndrome type ID gene (Ush1D) to chromosome 10. Hum Mol Genet (1996) 1.69
Biochemical changes in the collagen of the palmar fascia in patients with Dupuytren's disease. J Bone Joint Surg Am (1981) 1.69
Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study. Ann Intern Med (1992) 1.68
Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus. Hum Mol Genet (2001) 1.68
Challenge test battery in chronic urticaria. Br J Dermatol (1976) 1.67
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Prognostic value of FDG PET imaging in malignant pleural mesothelioma. J Nucl Med (1999) 1.67
Localization of Usher syndrome type II to chromosome 1q. Genomics (1990) 1.67
A single dose of endotoxin increases intestinal permeability in healthy humans. Arch Surg (1988) 1.66
Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Trélat, and multiple acrochordons. A possible role for alpha-transforming growth factor in cutaneous paraneoplastic syndromes. N Engl J Med (1987) 1.66
Cancer incidence among Canadian kidney transplant recipients. Am J Transplant (2007) 1.66
Bioregulation of lysosomal enzyme secretion from human neutrophils: roles of guanosine 3':5'-monophosphate and calcium in stimulus-secretion coupling. Proc Natl Acad Sci U S A (1975) 1.65
Nonsyndromic hearing impairment is associated with a mutation in DFNA5. Nat Genet (1998) 1.63
Why retrobulbar anaesthesia? Br J Ophthalmol (1988) 1.63
Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice. Gut (2005) 1.63
Mutants of Anabaena cylindrica altered in heterocyst spacing. Arch Microbiol (1975) 1.62
Serum iron and risk of fatal acute myocardial infarction. Epidemiology (1994) 1.61
A common founder for the 35delG GJB2 gene mutation in connexin 26 hearing impairment. J Med Genet (2001) 1.61
Passive and active smoking and breast cancer risk in Canada, 1994-97. Cancer Causes Control (2000) 1.60
Related cell-surface antigens expressed with positional specificity in Drosophila imaginal discs. Proc Natl Acad Sci U S A (1984) 1.60
Ten per cent polarized optical emission from GRB 090102. Nature (2009) 1.58
Highly polarized light from stable ordered magnetic fields in GRB 120308A. Nature (2013) 1.57
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Performance of a whole-body PET scanner using curve-plate NaI(Tl) detectors. J Nucl Med (2001) 1.56
Giant-cell tumors of the bones of the hand. J Hand Surg Am (1980) 1.55
Mutations in the KCNQ4 gene are responsible for autosomal dominant deafness in four DFNA2 families. Hum Mol Genet (1999) 1.54
Effects of long-chain triglyceride emulsions on reticuloendothelial system function in humans. JPEN J Parenter Enteral Nutr (1990) 1.53
Increased intestinal permeability associated with infection in burn patients. Arch Surg (1988) 1.53
Fatal accidental childhood injuries in Canada. Can J Public Health (1987) 1.52
Evaluation of a practical technique for determining insulin requirements in diabetic patients receiving total parenteral nutrition. JPEN J Parenter Enteral Nutr (1993) 1.52
Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1. J Clin Invest (1989) 1.52
Abnormal movement of the arytenoid region during exercise presenting as exercise-induced asthma in an adolescent athlete. Chest (1994) 1.52
Studies in small bowel transplantation. Prevention of graft-versus-host disease with preservation of allograft function by donor pretreatment with antilymphocyte serum. Transplantation (1988) 1.52
Protein dynamics during refeeding of protein-depleted rats: effects of increasing amino acid intake by TPN or enteral continuous feeding. J Nutr (1984) 1.50
Stabilization and localization of Xist RNA are controlled by separate mechanisms and are not sufficient for X inactivation. J Cell Biol (1998) 1.49
Cervical cancer screening: are the 1989 recommendations still valid? National Workshop on Screening for Cancer of the Cervix. CMAJ (1996) 1.49
ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle. Biochem Biophys Res Commun (1994) 1.48
Allometric scaling in comparative biology: problems of concept and method. Am J Physiol (1984) 1.48
The Lang lecture 1986. The enigma of primary open-angle glaucoma. Trans Ophthalmol Soc U K (1986) 1.48
Symptomatic hyperlipasemia after cardiopulmonary bypass: implications for enteral nutritional support. Nutrition (1993) 1.48
Albumin supplementation in the critically ill. A prospective, randomized trial. Arch Surg (1990) 1.47
[ The family physician's sentinel function studied with reference to referrals and referral cards]. Ned Tijdschr Geneeskd (1996) 1.47
Pyrazoline bisphosphonate esters as novel antiinflammatory and antiarthritic agents. J Med Chem (1993) 1.45
Endobronchial tumors in children: an uncommon clinical entity. Ann Otol Rhinol Laryngol (2001) 1.45
The human metabolic response to chronic ketosis without caloric restriction: preservation of submaximal exercise capability with reduced carbohydrate oxidation. Metabolism (1983) 1.45
Factors determining peripheral vein tolerance to amino acid infusions. Arch Surg (1979) 1.45
Premature deaths in Canada: impact, trends and opportunities for prevention. Can J Public Health (1991) 1.42
Mortality on Canadian Indian Reserves 1977-1982. Can J Public Health (1986) 1.42
Role of cytokines in AIDS wasting. Nutrition (1999) 1.42
Fish-oil-containing diet and platelet aggregation. Nutrition (1993) 1.42
Reducing arrhythmias associated with central venous catheter insertion or exchange. Nutrition (1992) 1.42
Management of congenital buccopharyngeal membrane. Cleft Palate Craniofac J (1997) 1.39