Published in Psychosom Med on May 30, 2001
An Assessment of Cognitive Function in Irritable Bowel Syndrome | NCT01304355
Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer. J Clin Oncol (2008) 3.30
Candidate mechanisms for chemotherapy-induced cognitive changes. Nat Rev Cancer (2007) 3.12
From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. Psychol Bull (2014) 2.39
Memory impairments with adjuvant anastrozole versus tamoxifen in women with early-stage breast cancer. Menopause (2007) 2.04
Anterior cingulate activation and error processing during interferon-alpha treatment. Biol Psychiatry (2005) 1.80
Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications. Neuroscience (2013) 1.55
Functional biomarkers of depression: diagnosis, treatment, and pathophysiology. Neuropsychopharmacology (2011) 1.44
Norman Cousins Lecture. Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface. Brain Behav Immun (2008) 1.42
IFN-alpha-induced motor slowing is associated with increased depression and fatigue in patients with chronic hepatitis C. Brain Behav Immun (2008) 1.30
Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals? J Affect Disord (2009) 1.28
A potential role for pro-inflammatory cytokines in regulating synaptic plasticity in major depressive disorder. Int J Neuropsychopharmacol (2009) 1.28
Malaise in the water maze: untangling the effects of LPS and IL-1beta on learning and memory. Brain Behav Immun (2008) 1.18
Neuropsychological dysfunction associated with cancer and cancer therapies: a conceptual review of an emerging target. Br J Cancer (2004) 1.15
At the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behaviour response. Brain Behav Immun (2012) 1.11
Cognitive dysfunction in chronic hepatitis C: a review. Dig Dis Sci (2007) 1.10
Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration. Front Cell Neurosci (2015) 0.96
Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy. Cytokine (2015) 0.94
Proinflammatory cytokines and their membrane-bound receptors are altered in the lymphocytes of schizophrenia patients. Schizophr Res (2015) 0.84
Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention. Behav Brain Funct (2010) 0.84
Inflammation at the intersection of behavior and somatic symptoms. Psychiatr Clin North Am (2011) 0.83
The impact of escitalopram on IL-2-induced neuroendocrine, immune, and behavioral changes in patients with malignant melanoma: preliminary findings. Neuropsychopharmacology (2013) 0.78
Management of Psychiatric Disease in Hepatitis C Treatment Candidates. Curr Hepat Rep (2010) 0.77
Inflammation as a mediator of the relationship between cortical thickness and metabolic syndrome. Brain Imaging Behav (2015) 0.76
A clinically relevant dose of cyclophosphamide chemotherapy impairs memory performance on the delayed spatial alternation task that is sustained over time as mice age. Neurotoxicology (2016) 0.75
LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1(ΔE9) transgenic mice. Alzheimers Res Ther (2016) 0.75
The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain. Oncotarget (2016) 0.75
Psychiatric clearance for patients started on interferon-alpha-based therapies. Am J Psychiatry (2013) 0.75
Inflammation, Self-Regulation, and Health: An Immunologic Model of Self-Regulatory Failure. Perspect Psychol Sci (2017) 0.75
Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma. Groupe Français d'Immunothérapie. N Engl J Med (1998) 4.93
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. Mol Psychiatry (2008) 3.28
Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy. Mol Psychiatry (2002) 2.87
Sickness behavior as a new target for drug development. Trends Pharmacol Sci (1992) 2.42
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Mol Psychiatry (2009) 2.36
Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer. Ann Oncol (2014) 2.29
Prediction of the depressive effects of interferon alfa therapy by the patient's initial affective state. N Engl J Med (1999) 2.14
Sequential sorafenib and sunitinib for renal cell carcinoma. J Urol (2009) 2.12
Prognostic factors of survival and rapid progression in 782 patients with metastatic renal carcinomas treated by cytokines: a report from the Groupe Français d'Immunothérapie. Ann Oncol (2002) 2.03
Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide. Neurobiol Aging (2007) 2.03
Taxane-induced glaucoma. Lancet (1999) 2.02
A new concept in neurodegeneration: TNFalpha is a silencer of survival signals. Trends Neurosci (2000) 1.93
Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Brain Res Mol Brain Res (1994) 1.90
A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide. Proc Natl Acad Sci U S A (1999) 1.90
Interleukin-10 in the brain. Crit Rev Immunol (2001) 1.89
Early depressive symptoms in cancer patients receiving interleukin 2 and/or interferon alfa-2b therapy. J Clin Oncol (2000) 1.57
Modulation of social memory in male rats by neurohypophyseal peptides. Psychopharmacology (Berl) (1987) 1.49
Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1. Proc Natl Acad Sci U S A (1992) 1.49
Role of interleukin-1beta and tumour necrosis factor-alpha in lipopolysaccharide-induced sickness behaviour: a study with interleukin-1 type I receptor-deficient mice. Eur J Neurosci (2000) 1.43
Cytokine signals propagate through the brain. Mol Psychiatry (2000) 1.42
Adjuvant therapy by BCG of non-Hodgkin's malignant lymphomas in a controlled trial: an update. Br J Haematol (1989) 1.39
Association between immune activation and early depressive symptoms in cancer patients treated with interleukin-2-based therapy. Psychoneuroendocrinology (2001) 1.37
Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat. Brain Res (1992) 1.37
The enzyme indoleamine 2,3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen. Brain Behav Immun (2002) 1.35
Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120. Neurobiol Aging (2006) 1.33
Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism. C R Acad Sci III (1994) 1.33
IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3'-kinase. J Immunol (2001) 1.33
Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression. Am J Physiol Regul Integr Comp Physiol (2000) 1.33
Role of IL-6 in cytokine-induced sickness behavior: a study with IL-6 deficient mice. Physiol Behav (2000) 1.32
Synergy between tumor necrosis factor alpha and interleukin-1 in the induction of sickness behavior in mice. Psychoneuroendocrinology (1994) 1.31
Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1beta and inducible nitric oxide synthase in rat brain. Neuroscience (1999) 1.31
Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS. Am J Physiol (1995) 1.29
Everolimus in metastatic renal cell carcinoma: Subgroup analysis of patients with 1 or 2 previous vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapies enrolled in the phase III RECORD-1 study. Eur J Cancer (2011) 1.29
Central injection of IL-10 antagonizes the behavioural effects of lipopolysaccharide in rats. Psychoneuroendocrinology (1999) 1.28
The vagus nerve mediates behavioural depression, but not fever, in response to peripheral immune signals; a functional anatomical analysis. Eur J Neurosci (2000) 1.23
Gonadal steroids influence the involvement of arginine vasopressin in social recognition in mice. Psychoneuroendocrinology (1993) 1.22
First-line bevacizumab combined with reduced dose interferon-alpha2a is active in patients with metastatic renal cell carcinoma. Ann Oncol (2008) 1.18
Differential effects of lipopolysaccharide on pup retrieving and nest building in lactating mice. Brain Behav Immun (1997) 1.17
Central administration of rat IL-6 induces HPA activation and fever but not sickness behavior in rats. Am J Physiol (1999) 1.14
Risk model for severe anemia requiring red blood cell transfusion after cytotoxic conventional chemotherapy regimens. The Elypse 1 Study Group. J Clin Oncol (1999) 1.14
Pyrogens specifically disrupt the acquisition of a task involving cognitive processing in the rat. Brain Behav Immun (1995) 1.13
Social recognition does not involve vasopressinergic neurotransmission in female rats. Brain Res (1990) 1.13
Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide. Eur J Neurosci (2008) 1.12
Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma. Ann Oncol (2012) 1.12
Androgen-dependent vasopressinergic neurons are involved in social recognition in rats. Brain Res (1990) 1.11
Vagotomy blocks behavioural effects of interleukin-1 injected via the intraperitoneal route but not via other systemic routes. Neuroreport (1996) 1.09
Behavioural effects of peripherally injected interleukin-1: role of prostaglandins. Brain Res (1991) 1.04
Attentional and mnemonic deficits associated with infectious disease in humans. Psychol Med (1999) 1.04
Stress in farm animals: a need for reevaluation. J Anim Sci (1983) 1.04
Lipopolysaccharide and interleukin-1 depress food-motivated behavior in mice by a vagal-mediated mechanism. Brain Behav Immun (1995) 1.04
Centrally injected arginine vasopressin (AVP) facilitates social memory in rats. Neurosci Lett (1987) 1.03
Arterial hypertension and clinical benefit of sunitinib, sorafenib and bevacizumab in first and second-line treatment of metastatic renal cell cancer. Ann Oncol (2009) 1.03
Incidence of large oesophageal varices in patients with cirrhosis: application to prophylaxis of first bleeding. Gut (1990) 1.02
Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor. J Clin Invest (1992) 1.01
Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta. Eur Cytokine Netw (1998) 1.01
Interleukin-1 mediates behavioural but not metabolic effects of tumor necrosis factor alpha in mice. Eur J Pharmacol (1991) 1.01
Mechanisms of sickness-induced decreases in food-motivated behavior. Neurosci Biobehav Rev (1996) 0.99
Adrenalectomy enhances pro-inflammatory cytokines gene expression, in the spleen, pituitary and brain of mice in response to lipopolysaccharide. Brain Res Mol Brain Res (1996) 0.98
Vagotomy attenuates behavioural effects of interleukin-1 injected peripherally but not centrally. Neuroreport (1996) 0.98
Central and peripheral prostaglandins are involved in sickness behavior in birds. Physiol Behav (1993) 0.98
In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide. Endocrinology (1998) 0.97
Differential effects of IL-1ra on sickness behavior and weight loss induced by IL-1 in rats. Brain Res (1995) 0.97
Tyrosine kinase inhibition in renal cell carcinoma and gastrointestinal stromal tumours: case reports. Ann Oncol (2009) 0.97
Social and individual recognition in rodents: Methodological aspects and neurobiological bases. Behav Processes (2002) 0.97
A risk model for thrombocytopenia requiring platelet transfusion after cytotoxic chemotherapy. Blood (1998) 0.97
The pituitary gland is required for protection against lethal effects of Salmonella typhimurium. Proc Natl Acad Sci U S A (1991) 0.97
Role of interferon-gamma in counteracting the suppressive effects of transforming growth factor-beta 2 and glucocorticoids on the production of tumor necrosis factor-alpha. J Leukoc Biol (1990) 0.97
C3H/HeJ mice are refractory to lipopolysaccharide in the brain. Brain Res (1997) 0.96
Diffusion and action of intracerebroventricularly injected interleukin-1 in the CNS. Neuroscience (2000) 0.96
Activation of protein kinase C-zeta and phosphatidylinositol 3'-kinase and promotion of macrophage differentiation by insulin-like growth factor-I. J Immunol (1998) 0.95
Expression and localization of p80 and p68 interleukin-1 receptor proteins in the brain of adult mice. J Neuroimmunol (1999) 0.95
Effect of floor area restriction upon performance, behavior and physiology of growing-finishing pigs. J Anim Sci (1987) 0.95
Cytokines in metastatic renal cell carcinoma: is it useful to switch to interleukin-2 or interferon after failure of a first treatment? Groupe Français d'Immunothérape. J Clin Oncol (1999) 0.94
Reduction in food and water intake induced by microinjection of interleukin-1 beta in the ventromedial hypothalamus of the rat. Physiol Behav (1994) 0.94
Corticotropin-releasing factor antagonist blocks stress-induced fighting in rats. Regul Pept (1987) 0.94
Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1beta in the rat. Psychopharmacology (Berl) (2001) 0.94
IL-4 and insulin-like growth factor-I inhibit the decline in Bcl-2 and promote the survival of IL-3-deprived myeloid progenitors. J Immunol (1997) 0.94
Interleukin-1beta-converting enzyme-deficient mice resist central but not systemic endotoxin-induced anorexia. Am J Physiol (1998) 0.93
Behavioural evidence for partial agonist properties of RO 15-1788, a benzodiazepine receptor antagonist. Eur J Pharmacol (1982) 0.93
Neuroinflammation and comorbidity of pain and depression. Pharmacol Rev (2013) 0.93
Vagotomy attenuates the behavioural but not the pyrogenic effects of interleukin-1 in rats. Auton Neurosci (2000) 0.92
Expression of type I and type II interleukin-1 receptors in mouse brain. Brain Res Mol Brain Res (1994) 0.92
Behavioral, physiological and functional aspects of stereotyped behavior: a review and a re-interpretation. J Anim Sci (1986) 0.92
Rat microglial cells secrete predominantly the precursor of interleukin-1beta in response to lipopolysaccharide. Eur J Neurosci (2001) 0.92
Interleukin-1 induces conditioned taste aversion in rats: a possible explanation for its pituitary-adrenal stimulating activity. Brain Res (1988) 0.91
Reduction in superoxide anion secretion and bactericidal activity of neutrophils from aged rats: reversal by the combination of gamma interferon and growth hormone. Infect Immun (1994) 0.91
Tumor necrosis factor(alpha) and insulin-like growth factor-I in the brain: is the whole greater than the sum of its parts? J Neuroimmunol (2001) 0.91
How the immune and nervous systems interact during disease-associated anorexia. Nutrition (2001) 0.91
Central interleukin-1 receptors as mediators of sickness. Ann N Y Acad Sci (1997) 0.91
Routinely performed multiparametric magnetic resonance imaging helps to differentiate common subtypes of renal tumours. Eur Radiol (2014) 0.90
Stress downregulates lipopolysaccharide-induced expression of proinflammatory cytokines in the spleen, pituitary, and brain of mice. Brain Behav Immun (1995) 0.90
Multicentre EORTC study 16997: feasibility and phase II trial of farnesyl transferase inhibitor & gemcitabine combination in salvage treatment of advanced urothelial tract cancers. Eur J Cancer (2005) 0.90
Effect of diazepam on performance of pigs in a progressive ratio schedule. Physiol Behav (1976) 0.89
Behavioural, physiological and immunological consequences of social status and aggression in chronically coexisting resident-intruder dyads of male rats. Physiol Behav (1986) 0.89
Regulation of cytokine gene expression in the central nervous system by glucocorticoids: mechanisms and functional consequences. Psychoneuroendocrinology (1997) 0.89
Phosphatidylinositol 3'-kinase, but not S6-kinase, is required for insulin-like growth factor-I and IL-4 to maintain expression of Bcl-2 and promote survival of myeloid progenitors. J Immunol (1999) 0.88