Published in Oncogene on May 31, 2001
p53 isoforms can regulate p53 transcriptional activity. Genes Dev (2005) 6.76
p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev (2004) 6.40
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72
p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53. Cell Death Differ (2011) 1.94
Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. Mol Cell Biol (2002) 1.89
The p53 family and programmed cell death. Oncogene (2008) 1.81
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A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest (2010) 1.73
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Splitting p63. Am J Hum Genet (2002) 1.62
RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript. Genes Dev (2006) 1.58
DeltaNp73beta is active in transactivation and growth suppression. Mol Cell Biol (2004) 1.56
The C terminus of p53 family proteins is a cell fate determinant. Mol Cell Biol (2005) 1.45
Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression. Am J Pathol (2011) 1.39
SSRP1 functions as a co-activator of the transcriptional activator p63. EMBO J (2002) 1.39
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Claudin-1 is a p63 target gene with a crucial role in epithelial development. PLoS One (2008) 1.20
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RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability. Proc Natl Acad Sci U S A (2010) 1.14
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DNA-binding and transactivation activities are essential for TAp63 protein degradation. Mol Cell Biol (2005) 1.04
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Pirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63. J Invest Dermatol (2012) 0.93
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Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation. Mol Cell Biol (2009) 0.90
Senescence regulation by the p53 protein family. Methods Mol Biol (2013) 0.88
DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation. Mol Cancer (2010) 0.88
DeltaNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkA. Mol Cell Biol (2007) 0.88
Poly (C)-binding protein 1 regulates p63 expression through mRNA stability. PLoS One (2013) 0.87
The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63. Oncogene (2007) 0.86
Cataloging and organizing p73 interactions in cell cycle arrest and apoptosis. Nucleic Acids Res (2008) 0.86
P63 regulates tubular formation via epithelial-to-mesenchymal transition. Oncogene (2013) 0.86
Pathway Regulation of p63, a Director of Epithelial Cell Fate. Front Endocrinol (Lausanne) (2015) 0.85
Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein. J Biol Chem (2012) 0.85
Expansion on stromal cells preserves the undifferentiated state of human hematopoietic stem cells despite compromised reconstitution ability. PLoS One (2013) 0.84
p63 directly induces expression of Alox12, a regulator of epidermal barrier formation. Exp Dermatol (2009) 0.84
Interferon-α acts on the S/G2/M phases to induce apoptosis in the G1 phase of an IFNAR2-expressing hepatocellular carcinoma cell line. J Biol Chem (2014) 0.83
ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2. BMC Cancer (2014) 0.83
Regulation of p63 protein stability via ubiquitin-proteasome pathway. Biomed Res Int (2014) 0.83
p53-independent mechanisms regulate the P2-MDM2 promoter in adult astrocytic tumours. Br J Cancer (2008) 0.82
p63 transcriptionally regulates the expression of matrix metallopeptidase 13. Oncotarget (2014) 0.82
Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer. Endocr Relat Cancer (2014) 0.82
RNA-binding protein RBM24 regulates p63 expression via mRNA stability. Mol Cancer Res (2013) 0.82
HuR is necessary for mammary epithelial cell proliferation and polarity at least in part via ΔNp63. PLoS One (2012) 0.82
Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment. Stem Cell Res (2013) 0.81
Scotin: A new p63 target gene expressed during epidermal differentiation. Biochem Biophys Res Commun (2007) 0.81
Inhibition of p63 transcriptional activity by p14ARF: functional and physical link between human ARF tumor suppressor and a member of the p53 family. Mol Cell Biol (2004) 0.81
Induction of the small heat shock protein alphaB-crystallin by genotoxic stress is mediated by p53 and p73. Breast Cancer Res Treat (2009) 0.81
∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. Oncotarget (2014) 0.81
Alterations of p63 and p73 in human cancers. Subcell Biochem (2014) 0.81
Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol (2013) 0.80
Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63. J Skin Cancer (2013) 0.80
Serine 123 phosphorylation modulates p21 protein stability and activity by suppressing ubiquitin-independent proteasomal degradation. J Biol Chem (2012) 0.80
XIAP RING domain mediates miR-4295 expression and subsequently inhibiting p63α protein translation and promoting transformation of bladder epithelial cells. Oncotarget (2016) 0.80
Potential utility of p63 expression in differential diagnosis of non-small-cell lung carcinoma and its effect on prognosis of the disease. Med Sci Monit (2014) 0.79
Impaired delta NP63 expression is associated with poor tumor development in transitional cell carcinoma of the bladder. J Korean Med Sci (2008) 0.79
Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification. Nat Commun (2016) 0.79
p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function. Aging (Albany NY) (2016) 0.78
p63α protein upregulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion. J Biol Chem (2017) 0.78
14-3-3σ Gene Loss Leads to Activation of the Epithelial to Mesenchymal Transition Due to the Stabilization of c-Jun Protein. J Biol Chem (2016) 0.77
Different regulation of limb development by p63 transcript variants. PLoS One (2017) 0.75
Upregulation of cell adhesion through delta Np63 silencing in human 5637 bladder cancer cells. Asian J Androl (2012) 0.75
Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response. Sci Rep (2017) 0.75
Oncogenic Intra-p53 Family Member Interactions in Human Cancers. Front Oncol (2016) 0.75
p63α modulates c-Myc activity via direct interaction and regulation of MM1 protein stability. Oncotarget (2016) 0.75
ΔNp63α Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion. PLoS One (2016) 0.75
The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System. Int J Mol Sci (2016) 0.75
The dominant-negative interplay between p53, p63 and p73: A family affair. Oncotarget (2016) 0.75
C-terminal cleavage of DeltaNp63alpha is associated with TSA-induced apoptosis in immortalized corneal epithelial cells. Invest Ophthalmol Vis Sci (2010) 0.75
ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells. BMC Cancer (2016) 0.75
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