Published in Am J Pathol on July 01, 2001
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51
Tumor angiogenesis: therapeutic implications. N Engl J Med (1971) 35.36
Lessons from hereditary colorectal cancer. Cell (1996) 25.73
ras oncogenes in human cancer: a review. Cancer Res (1989) 22.03
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell (1992) 16.53
p21 is a universal inhibitor of cyclin kinases. Nature (1993) 15.55
What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst (1990) 13.41
Suppression of human colorectal carcinoma cell growth by wild-type p53. Science (1990) 11.18
Integrins and signal transduction pathways: the road taken. Science (1995) 10.71
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature (1996) 9.36
The mitogen-activated protein kinase signal transduction pathway. J Biol Chem (1993) 8.77
Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature (1997) 7.20
Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin. Proc Natl Acad Sci U S A (1981) 4.34
Growth factors and cancer. Cancer Res (1986) 3.48
Calnexin: a membrane-bound chaperone of the endoplasmic reticulum. Trends Biochem Sci (1994) 3.32
The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes. Science (1986) 3.32
Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes. J Immunol (1981) 3.02
Microvascular pericytes contain muscle and nonmuscle actins. J Cell Biol (1985) 2.91
Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. J Immunol (1983) 2.65
Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps. Biochemistry (1998) 2.51
Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. Proc Natl Acad Sci U S A (1982) 2.42
Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family. Nature (1998) 2.28
Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res (1984) 2.17
Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity. Proc Natl Acad Sci U S A (1998) 1.88
Immunotoxins. Cell (1986) 1.82
Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450. EMBO J (1999) 1.75
Production of monoclonal antibodies reacting with peripheral blood mononuclear cell surface differentiation antigens. J Immunol (1980) 1.75
Monoclonal mouse antibodies raised against human lung carcinoma. Cancer Res (1986) 1.75
Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium. Cancer Res (1992) 1.73
Surface antigen CD98(4F2): not a single membrane protein, but a family of proteins with multiple functions. J Membr Biol (2000) 1.69
The retinoblastoma protein and the regulation of cell cycling. Trends Biochem Sci (1992) 1.68
Truncation of the human EGF receptor leads to differential transforming potentials in primary avian fibroblasts and erythroblasts. EMBO J (1988) 1.63
Signal transduction by cell adhesion receptors. Biochim Biophys Acta (1995) 1.55
The neu-oncogene: signal transduction pathways, transformation mechanisms and evolving therapies. Oncogene (1994) 1.51
Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance. J Biol Chem (1998) 1.50
Interleukin-4 receptor-directed cytotoxin therapy of AIDS-associated Kaposi's sarcoma tumors in xenograft model. Nat Med (1999) 1.48
Functional sorting of actin isoforms in microvascular pericytes. J Cell Biol (1989) 1.48
A microchemical facility for the analysis and synthesis of genes and proteins. Nature (1984) 1.47
Differential expression of cell activation markers after stimulation of resting human B lymphocytes. J Immunol (1984) 1.47
Indirect association of ezrin with F-actin: isoform specificity and calcium sensitivity. J Cell Biol (1995) 1.45
IL-2-mediated T cell proliferation in humans is blocked by a monoclonal antibody directed against monomorphic determinants of HLA-DR antigens. J Exp Med (1982) 1.44
Inhibition of human melanoma cell growth in vitro by monoclonal anti-GD3-ganglioside antibody. Cancer Res (1984) 1.40
Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines. J Immunol (1982) 1.38
Characterization of monoclonal antibodies B1 and B3 that react with mucinous adenocarcinomas. Cancer Res (1991) 1.34
Stimulation of system y(+)-like amino acid transport by the heavy chain of human 4F2 surface antigen in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1992) 1.27
Malignant transformation of NIH3T3 cells by overexpression of early lymphocyte activation antigen CD98. Biochem Biophys Res Commun (1999) 1.26
Phase I immunotoxin trial in patients with B-cell lymphoma. Cancer Res (1991) 1.26
Structure, expression and regulation of the murine 4F2 heavy chain. Nucleic Acids Res (1989) 1.23
Treatment of advanced solid tumors with immunotoxin LMB-1: an antibody linked to Pseudomonas exotoxin. Nat Med (1996) 1.19
Cloning and expression of the tumor-associated antigen L6. Proc Natl Acad Sci U S A (1992) 1.18
Tumor sialomucin complexes as tumor antigens and modulators of cellular interactions and proliferation. J Cell Sci (1992) 1.07
Inhibition of tumor cell growth in vitro by murine monoclonal antibodies that recognize a proliferation-associated cell surface antigen system in rats and humans. Cancer Res (1986) 1.07
Analysis of the expression of the 4F2 surface antigen in normal and neoplastic fibroblastic human cells of embryonic and adult origin. Exp Cell Res (1985) 1.00
Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2. Proc Natl Acad Sci U S A (1987) 0.99
Mitosis-specific negative regulation of epidermal growth factor receptor, triggered by a decrease in ligand binding and dimerization, can be overcome by overexpression of receptor. J Biol Chem (1997) 0.93
Isolation and characterization of a heterodimeric surface antigen on human melanoma cells and evidence that it is the 4F2 cell activation/proliferation molecule. Int J Cancer (1990) 0.92
Tumor markers in cancer diagnosis and prognosis. CA Cancer J Clin (1988) 0.89
Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-Tac Fv fragment and truncated Pseudomonas exotoxin. Int J Cancer (1994) 0.88
The monoclonal antibodies Trop-4 and 4F2 detect the same membrane antigen that is expressed at an early stage of lymphocyte activation and is retained on secondary lymphocytes. J Immunol (1986) 0.88
4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not of adult origin. J Cell Biol (1984) 0.88
Cell surface glycoproteins involved in the stimulation of interleukin 1-dependent interleukin 2 production by a subline of EL4 thymoma cells. II. Structure, biosynthesis, and maturation. J Immunol (1985) 0.84
Effects of monoclonal antibodies that block transferrin receptor function on the in vivo growth of a syngeneic murine leukemia. Cancer Res (1987) 0.82
Fluctuations in proline and other free amino acids during the mitotic cycle of the myxomycete Physarum polycephalum. Eur J Biochem (1979) 0.82
Cell cycle-dependent regulation of p185neu: a relationship between disruption of this regulation and transformation. Proc Natl Acad Sci U S A (1995) 0.81
Recombinant immunotoxins. Breast Cancer Res Treat (1996) 0.79
Purification and characterization of a new 85-kDa glycoprotein antigen from human breast tumor. Int J Cancer (1995) 0.78
Evaluation of cell surface antigens as potential targets for recombinant tumor toxins. Cancer Lett (1997) 0.76
PR1--a monoclonal antibody that reacts with an antigen on the surface of normal and malignant prostate cells. J Natl Cancer Inst (1993) 0.76
Murine monoclonal antibodies reactive with a variety of androgen independent Dunning rat prostate adenocarcinoma sublines also reactive with human prostate adenocarcinoma. J Urol (1991) 0.76
Monoclonal antibody PD41 recognizes an antigen restricted to prostate adenocarcinomas. Cancer Res (1991) 0.76
Amino acid pools in mitotic and interphase HeLa cells. Exp Cell Res (1981) 0.76
Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest (1993) 4.54
Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. J Neurosci (1998) 3.45
Microvascular pericytes contain muscle and nonmuscle actins. J Cell Biol (1985) 2.91
Relation between cell activity and the distribution of cytoplasmic actin and myosin. J Cell Biol (1981) 2.36
Beta actin and its mRNA are localized at the plasma membrane and the regions of moving cytoplasm during the cellular response to injury. J Cell Biol (1991) 2.19
Actin filament stress fibers in vascular endothelial cells in vivo. Science (1983) 2.12
Comparison of purified anti-actin and fluorescent-heavy meromyosin staining patterns in dividing cells. J Cell Biol (1979) 2.04
Calpain regulates actin remodeling during cell spreading. J Cell Biol (1998) 1.90
Actin localization in fixed dividing cells stained with fluorescent heavy meromyosin. Exp Cell Res (1978) 1.77
Electron microscopic localization of cytoplasmic myosin with ferritin-labeled antibodies. J Cell Biol (1981) 1.52
Functional sorting of actin isoforms in microvascular pericytes. J Cell Biol (1989) 1.48
Indirect association of ezrin with F-actin: isoform specificity and calcium sensitivity. J Cell Biol (1995) 1.45
Radial keratotomy. II. Role of the myofibroblast in corneal wound contraction. Invest Ophthalmol Vis Sci (1992) 1.27
Extracellular matrix modulation of endothelial cell shape and motility following injury in vitro. J Cell Sci (1985) 1.25
Inhibition of calpain blocks platelet secretion, aggregation, and spreading. J Biol Chem (1999) 1.23
Correlated distribution of actin, myosin, and microtubules at the leading edge of migrating Swiss 3T3 fibroblasts. Cell Motil Cytoskeleton (1989) 1.22
Beta cap73: a novel beta actin-specific binding protein. Cell Motil Cytoskeleton (1996) 1.17
beta-Actin is confined to structures having high capacity of remodelling in developing and adult rat cerebellum. Eur J Neurosci (1998) 1.11
Phalloidin binding and rheological differences among actin isoforms. Biochemistry (1996) 1.10
Characterization of avascular corneal wound healing fibroblasts. New insights into the myofibroblast. Am J Pathol (1987) 1.05
Immunolocalization of the vacuolar-type (H+)-ATPase from clathrin-coated vesicles. Eur J Cell Biol (1991) 1.04
Contractile proteins in endothelial cells. Ann N Y Acad Sci (1982) 0.97
Isolation and in vitro characterization of human dermal microvascular pericytes. Microvasc Res (2001) 0.96
Pulmonary microvascular endothelial cell contractility on silicone rubber substrate. J Cell Physiol (1989) 0.94
Optic nerve injury alters basic fibroblast growth factor localization in the retina and optic tract. J Neurosci (1994) 0.93
Hemodynamics and the vascular endothelial cytoskeleton. J Cell Biol (1987) 0.92
Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading. J Thromb Haemost (2012) 0.90
Extracellular matrix-cytoskeletal interactions in vascular cells. Tissue Cell (1987) 0.87
Substratum-induced stress fiber assembly in vascular endothelial cells during spreading in vitro. J Cell Sci (1990) 0.87
Density-dependent accumulation of basic fibroblast growth factor in the subendothelial matrix. Eur J Cell Biol (1992) 0.87
Capillary endothelial cell migration: loss of stress fibres in response to retina-derived growth factor. J Muscle Res Cell Motil (1984) 0.85
Preparation of fluorescent basic fibroblast growth factor: localization in living retinal microvascular endothelial cells. Exp Eye Res (1992) 0.82
Pericyte growth and contractile phenotype: modulation by endothelial-synthesized matrix and comparison with aortic smooth muscle. J Cell Physiol (1993) 0.82
The mechanics of vascular cell motility. Microcirculation (1998) 0.81
Propranolol targets the contractility of infantile haemangioma-derived pericytes. Br J Dermatol (2014) 0.80
Characterization of microvascular cell cultures from normotensive and hypertensive rat brains: pericyte-endothelial cell interactions in vitro. Tissue Cell (1987) 0.80
Computer-assisted analysis of the vascular endothelial cell motile response to injury. Comput Biomed Res (1988) 0.80
Measurement of glucose consumption by hybridoma cells growing in hollow fiber cartridge bioreactors: use of blood glucose self-monitoring devices. J Immunol Methods (1997) 0.79
Mechanisms of vein graft atherosclerosis: LDL metabolism and endothelial actin reorganization. J Vasc Surg (1991) 0.78
Static mechanical strain induces capillary endothelial cell cycle re-entry and sprouting. Phys Biol (2016) 0.76
Age-related and site-specific adaptation of the arterial endothelial cytoskeleton during atherogenesis. Am J Pathol (1988) 0.75
Bovine retinal microvascular pericytes : isolation, propagation, and identification. Methods Mol Med (2001) 0.75
Biomechanics of the arterial wall under simulated flow conditions. J Biomech (1988) 0.75
Experimental determination and mathematical model of the transient incorporation of cholesterol in the arterial wall. Bull Math Biol (1990) 0.75
Hemodynamics alter arterial low-density lipoprotein metabolism. J Vasc Surg (1989) 0.75