Published in Nature on July 05, 2001
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res (2002) 5.93
Apoptotic and autophagic cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci U S A (2004) 4.20
The role of mitochondria in apoptosis*. Annu Rev Genet (2009) 3.44
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Mitochondrial fission proteins regulate programmed cell death in yeast. Genes Dev (2004) 2.30
Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization. EMBO J (2003) 2.16
A korarchaeal genome reveals insights into the evolution of the Archaea. Proc Natl Acad Sci U S A (2008) 2.16
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A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout. Proc Natl Acad Sci U S A (2005) 1.93
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ZEN1 is a key enzyme in the degradation of nuclear DNA during programmed cell death of tracheary elements. Plant Cell (2002) 1.47
CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation. EMBO J (2003) 1.45
Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: Differential involvement of caspase-3 and endonuclease G. J Neurovirol (2004) 1.38
Mitochondrial Ca(2+) and apoptosis. Cell Calcium (2012) 1.36
Mechanisms of apoptosis in the heart. J Clin Immunol (2003) 1.29
Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation. Genes Dev (2002) 1.29
Galectin-1 induces nuclear translocation of endonuclease G in caspase- and cytochrome c-independent T cell death. Cell Death Differ (2004) 1.29
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Cuts can kill: the roles of apoptotic nucleases in cell death and animal development. Chromosoma (2006) 1.22
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Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites. Parasit Vectors (2011) 1.13
EXOG, a novel paralog of Endonuclease G in higher eukaryotes. Nucleic Acids Res (2008) 1.13
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The Drosophila melanogaster Gene cg4930 Encodes a High Affinity Inhibitor for Endonuclease G. J Biol Chem (2009) 1.05
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Molecular characterization of propolis-induced cell death in Saccharomyces cerevisiae. Eukaryot Cell (2010) 1.04
Endonuclease G is required for early embryogenesis and normal apoptosis in mice. Proc Natl Acad Sci U S A (2003) 1.02
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease. EMBO J (2013) 1.02
Endonuclease G: a role for the enzyme in recombination and cellular proliferation. Proc Natl Acad Sci U S A (2006) 1.01
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CHIP has a protective role against oxidative stress-induced cell death through specific regulation of endonuclease G. Cell Death Dis (2013) 0.93
Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation. Mol Cell Biol (2008) 0.90
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Dynorphin A (1-17) induces apoptosis in striatal neurons in vitro through alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor-mediated cytochrome c release and caspase-3 activation. Neuroscience (2003) 0.86
Mitofusin 1 is negatively regulated by microRNA 140 in cardiomyocyte apoptosis. Mol Cell Biol (2014) 0.86
Programmed cell death in aging. Ageing Res Rev (2015) 0.86
The roles and acting mechanism of Caenorhabditis elegans DNase II genes in apoptotic dna degradation and development. PLoS One (2009) 0.85
The Caenorhabditis elegans pvl-5 gene protects hypodermal cells from ced-3-dependent, ced-4-independent cell death. Genetics (2004) 0.84
Adenine nucleotide translocator cooperates with core cell death machinery to promote apoptosis in Caenorhabditis elegans. Mol Cell Biol (2009) 0.84
Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway. Nat Struct Mol Biol (2014) 0.82
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Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans. J Biol Chem (2012) 0.81
Mutagenesis identifies the critical amino acid residues of human endonuclease G involved in catalysis, magnesium coordination, and substrate specificity. J Biomed Sci (2009) 0.81
Importance of oligodendrocyte protection, BBB breakdown and inflammation for remyelination. Expert Rev Neurother (2010) 0.80
On the intrinsic disorder status of the major players in programmed cell death pathways. F1000Res (2013) 0.79
Small DNA pieces in C. elegans are intermediates of DNA fragmentation during apoptosis. PLoS One (2010) 0.79
C. elegans EIF-3.K promotes programmed cell death through CED-3 caspase. PLoS One (2012) 0.78
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Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G. Cell Rep (2016) 0.78
Recombinant expression, biophysical characterization, and cardiolipin-induced changes of two Caenorhabditis elegans cytochrome c proteins. Biochemistry (2013) 0.78
A novel mechanism underlies caspase-dependent conversion of the dicer ribonuclease into a deoxyribonuclease during apoptosis. Cell Res (2013) 0.77
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination. Nucleic Acids Res (2014) 0.77
Programmed cell death induced by (-)-8,9-dehydroneopeltolide in human promyelocytic leukemia HL-60 cells under energy stress conditions. Mar Drugs (2014) 0.77
Novel cytoprotective inhibitors for apoptotic endonuclease G. DNA Cell Biol (2014) 0.76
Residual body removal during spermatogenesis in C. elegans requires genes that mediate cell corpse clearance. Development (2012) 0.76
Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture. PLoS One (2016) 0.75
Crystallization and preliminary X-ray crystallographic studies of the CIDE-domain complex between Drep2 and Drep3 from Drosophila melanogaster. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75
Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer. Nucleic Acids Res (2016) 0.75
Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival. PLoS One (2014) 0.75
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Purification, crystallization and data collection of the apoptotic nuclease endonuclease G. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.75
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Essential roles of Caspase-3 in facilitating Myc-induced genetic instability and carcinogenesis. Elife (2017) 0.75
Caenorhabditis elegans ATPase inhibitor factor 1 (IF1) MAI-2 preserves the mitochondrial membrane potential (Δψm) and is important to induce germ cell apoptosis. PLoS One (2017) 0.75
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