Published in Genes Dev on August 01, 2001
Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis. Mol Cell Biol (2003) 2.90
Nodal morphogens. Cold Spring Harb Perspect Biol (2009) 2.09
A poised chromatin platform for TGF-β access to master regulators. Cell (2011) 1.81
Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer. J Cell Physiol (2010) 1.81
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway. Mol Cell Biol (2002) 1.80
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells. EMBO J (2004) 1.77
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning. Genes Dev (2002) 1.68
Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells. Mol Cell Biol (2002) 1.53
TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability. Endocrinology (2013) 1.53
Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells. J Cell Biol (2003) 1.52
Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proc Natl Acad Sci U S A (2006) 1.47
Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways. Oncogene (2009) 1.47
Highly sensitive and specific bioassay for measuring bioactive TGF-beta. BMC Cell Biol (2006) 1.42
EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes Dev (2003) 1.37
Cripto forms a complex with activin and type II activin receptors and can block activin signaling. Proc Natl Acad Sci U S A (2003) 1.35
Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells. Prostate (2011) 1.34
Emerging roles for the transforming growth factor-{beta} superfamily in regulating adiposity and energy expenditure. Endocr Rev (2010) 1.32
TGF-β control of stem cell differentiation genes. FEBS Lett (2012) 1.25
Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity. Proc Natl Acad Sci U S A (2008) 1.22
Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions. PLoS Genet (2011) 1.20
Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. PLoS Biol (2004) 1.19
SOX7 and SOX18 are essential for cardiogenesis in Xenopus. Dev Dyn (2005) 1.17
Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function. Proc Natl Acad Sci U S A (2008) 1.16
Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish. BMC Dev Biol (2007) 1.16
Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis. EMBO Rep (2006) 1.13
Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: implication in the pathogenesis of preeclampsia. Am J Pathol (2011) 1.09
Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation. EMBO J (2008) 1.09
The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling. Genes Dev (2002) 1.07
ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse. Mol Cell Biol (2004) 1.06
Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. Genes Dev (2012) 1.06
Multiple functions of Cerberus cooperate to induce heart downstream of Nodal. Dev Biol (2006) 1.06
Nodal signaling activates differentiation genes during zebrafish gastrulation. Dev Biol (2007) 1.03
Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression. Breast Dis (2008) 1.03
Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto. Genes Dev (2003) 1.01
Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction. J Cell Biol (2008) 1.01
Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol (2010) 1.00
Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7. Mol Biol Cell (2008) 0.99
Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling. J Biol Chem (2010) 0.98
Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes. Am J Pathol (2005) 0.97
Expression and functional role of CRIPTO-1 in cutaneous melanoma. Br J Cancer (2011) 0.96
Nodal signals mediate interactions between the extra-embryonic and embryonic tissues in zebrafish. Dev Biol (2007) 0.92
Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis. FEBS Lett (2012) 0.91
beta-Catenin/TCF/LEF regulate expression of the short form human Cripto-1. Biochem Biophys Res Commun (2007) 0.90
Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells. Development (2012) 0.89
The genetic relationship between handedness and neurodevelopmental disorders. Trends Mol Med (2013) 0.89
Targeting the embryonic gene Cripto-1 in cancer and beyond. Expert Opin Ther Pat (2010) 0.89
Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis. Dev Biol (2010) 0.88
Nodal and activin receptor-like kinase 7 induce apoptosis in human breast cancer cell lines: Role of caspase 3. Int J Physiol Pathophysiol Pharmacol (2009) 0.87
Nodal expression in the uterus of the mouse is regulated by the embryo and correlates with implantation. Biol Reprod (2011) 0.87
Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling. Development (2011) 0.86
Cancer Stem Cells, EMT, and Developmental Pathway Activation in Pancreatic Tumors. Cancers (Basel) (2012) 0.85
Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol (2013) 0.85
Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin. Proc Natl Acad Sci U S A (2012) 0.85
Human Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypes. PLoS One (2015) 0.85
The competence of Xenopus blastomeres to produce neural and retinal progeny is repressed by two endo-mesoderm promoting pathways. Dev Biol (2007) 0.84
Nodal·Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation. J Biol Chem (2014) 0.82
A role for Vg1/Nodal signaling in specification of the intermediate mesoderm. Development (2013) 0.81
New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding. Int J Mol Sci (2015) 0.81
Plasticity underlies tumor progression: role of Nodal signaling. Cancer Metastasis Rev (2016) 0.81
Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation. Mol Endocrinol (2015) 0.80
Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity. Elife (2014) 0.79
Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells. Am J Physiol Endocrinol Metab (2012) 0.79
Divergence(s) in nodal signaling between aggressive melanoma and embryonic stem cells. Int J Cancer (2014) 0.79
Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis. PLoS One (2015) 0.78
ALK7 gene polymorphism is associated with metabolic syndrome risk and cardiovascular remodeling. Arq Bras Cardiol (2013) 0.78
Toward a better understanding of the interaction between TGF-β family members and their ALK receptors. J Mol Model (2012) 0.77
Antagonistic interactions in the zebrafish midline prior to the emergence of asymmetric gene expression are important for left-right patterning. Philos Trans R Soc Lond B Biol Sci (2016) 0.77
Nodal promotes glioblastoma cell growth. Front Endocrinol (Lausanne) (2012) 0.77
Rasl11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype. PLoS One (2008) 0.77
Noggin maintains pluripotency of human embryonic stem cells grown on Matrigel. Cell Prolif (2009) 0.76
Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic. J Biol Chem (2017) 0.75
Activin receptor-like kinases: a diverse family playing an important role in cancer. Am J Cancer Res (2016) 0.75
A novel crosstalk between Alk7 and cGMP signaling differentially regulates brown adipocyte function. Mol Metab (2015) 0.75
Subtilisin-like proprotein convertase activity is necessary for left-right axis determination in Xenopus neurula embryos. Dev Genes Evol (2006) 0.75
Extracellular interactions and ligand degradation shape the nodal morphogen gradient. Elife (2016) 0.75
Cerberus-Nodal-Lefty-Pitx signaling cascade controls left-right asymmetry in amphioxus. Proc Natl Acad Sci U S A (2017) 0.75
Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specification. EMBO Rep (2017) 0.75
TGFβ superfamily signaling and uterine decidualization. Reprod Biol Endocrinol (2017) 0.75
Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci U S A (1985) 68.48
TGF-beta signal transduction. Annu Rev Biochem (1998) 17.83
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J (1998) 10.01
The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev (1994) 5.65
Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell (1994) 4.53
Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos. Cell (1994) 4.24
Smad2 role in mesoderm formation, left-right patterning and craniofacial development. Nature (1998) 3.65
Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell (1991) 3.40
Zebrafish organizer development and germ-layer formation require nodal-related signals. Nature (1998) 3.21
The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature (1999) 3.19
Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature (1998) 3.16
The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell (1999) 3.15
A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development (1994) 3.12
Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell (1994) 2.98
Functional analysis of activins during mammalian development. Nature (1995) 2.71
Activin signalling and response to a morphogen gradient. Nature (1994) 2.70
A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta. Cell (1987) 2.64
Different phenotypes for mice deficient in either activins or activin receptor type II. Nature (1995) 2.62
Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature (1993) 2.45
Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature (1996) 2.35
Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell (1990) 2.22
Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development (1995) 2.16
Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature (1998) 2.10
The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. Genes Dev (1997) 2.09
Endodermal Nodal-related signals and mesoderm induction in Xenopus. Development (2000) 1.97
Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell (1994) 1.96
Upstream sequences required for tissue-specific activation of the cardiac actin gene in Xenopus laevis embryos. EMBO J (1986) 1.91
Mechanisms of left-right determination in vertebrates. Cell (2000) 1.85
cyclops encodes a nodal-related factor involved in midline signaling. Proc Natl Acad Sci U S A (1998) 1.75
Cloning of a second type of activin receptor and functional characterization in Xenopus embryos. Science (1992) 1.64
Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Dev Biol (1998) 1.56
A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell (1995) 1.52
The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse. Genes Dev (1998) 1.52
The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice. Dev Biol (1999) 1.51
The EGF-CFC gene family in vertebrate development. Trends Genet (2000) 1.47
BMP signaling is required for heart formation in vertebrates. Dev Biol (2000) 1.46
Two novel nodal-related genes initiate early inductive events in Xenopus Nieuwkoop center. Development (2000) 1.45
A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis. Development (1997) 1.43
The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature (1991) 1.39
Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction? EMBO J (1994) 1.31
Goosecoid expression in neurectoderm and mesendoderm is disrupted in zebrafish cyclops gastrulas. Dev Biol (1994) 1.24
Direct and continuous assessment by cells of their position in a morphogen gradient. Nature (1995) 1.22
Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis. Development (1999) 1.20
The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev Biol (1997) 1.20
A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system. J Biol Chem (1996) 1.17
Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer. Dev Biol (1997) 1.15
Membrane-anchorage of Cripto protein by glycosylphosphatidylinositol and its distribution during early mouse development. Mech Dev (2000) 1.15
The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds. Development (1997) 1.14
A two-step model for the fate determination of presumptive endodermal blastomeres in Xenopus embryos. Curr Biol (1999) 1.13
Zebrafish nodal-related 2 encodes an early mesendodermal inducer signaling from the extraembryonic yolk syncytial layer. Dev Biol (1998) 1.12
Functional differences among Xenopus nodal-related genes in left-right axis determination. Development (1997) 1.12
Vertebrate mesendoderm induction and patterning. Curr Opin Genet Dev (2000) 1.12
The Xenopus XIHbox 6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons. Development (1990) 1.11
Conversion of zebrafish blastomeres to an endodermal fate by TGF-beta-related signaling. Curr Biol (1998) 1.09
A role for the vegetally expressed Xenopus gene Mix.1 in endoderm formation and in the restriction of mesoderm to the marginal zone. Development (1998) 1.08
Xenopus GDF6, a new antagonist of noggin and a partner of BMPs. Development (1999) 1.06
The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development. Cell (1995) 1.05
Cardiac looping and the vertebrate left-right axis: antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway. Development (1999) 1.05
Activin signalling has a necessary function in Xenopus early development. Curr Biol (1997) 0.93
A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation. Development (1996) 0.93
The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line. J Biol Chem (2000) 0.93
Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain. Mol Cell Neurosci (1996) 0.91
A carboxyl-terminal truncated version of the activin receptor mediates activin signals in early Xenopus embryos. FEBS Lett (1992) 0.91
Embryonic expression and functional analysis of a Xenopus activin receptor. Dev Dyn (1992) 0.90
Multiple genes for Xenopus activin receptor expressed during early embryogenesis. FEBS Lett (1992) 0.85
The MH1 domains of smad2 and smad3 are involved in the regulation of the ALK7 signals. Biochem Biophys Res Commun (1999) 0.85
Differential effects on Xenopus development of interference with type IIA and type IIB activin receptors. Mech Dev (1997) 0.83
XTrR-I is a TGFbeta receptor and overexpression of truncated form of the receptor inhibits axis formation and dorsalising activity. Mech Dev (1998) 0.80
A type 1 serine/threonine kinase receptor that can dorsalize mesoderm in Xenopus. Proc Natl Acad Sci U S A (1995) 0.77
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem (1989) 11.06
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med (2001) 6.73
Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A (1985) 6.20
Molecular cloning and DNA sequence of the Arabidopsis thaliana alcohol dehydrogenase gene. Proc Natl Acad Sci U S A (1986) 5.64
Sequence determinants of cytosolic N-terminal protein processing. Eur J Biochem (1986) 5.59
Ethylene insensitivity conferred by Arabidopsis ERS gene. Science (1995) 4.87
A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml. Nucleic Acids Res (1997) 4.40
Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy (PATH) Alliance registry. Clin Infect Dis (2009) 4.19
Toward a unified genetic map of higher plants, transcending the monocot-dicot divergence. Nat Genet (1996) 4.08
Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc Natl Acad Sci U S A (1991) 3.95
Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors. Proc Natl Acad Sci U S A (1998) 3.94
Isolation of human glucose-6-phosphate dehydrogenase (G6PD) cDNA clones: primary structure of the protein and unusual 5' non-coding region. Nucleic Acids Res (1986) 3.86
Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol (1990) 3.80
Coronary heart-disease after treatment of hypertension. Lancet (1978) 3.78
Characteristics of short-chain alcohol dehydrogenases and related enzymes. Eur J Biochem (1991) 3.67
Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proc Natl Acad Sci U S A (1996) 3.56
ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis. Proc Natl Acad Sci U S A (1998) 3.48
Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol (1999) 3.28
Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells. Mol Cell Biol (1991) 3.25
Galanin - a novel biologically active peptide from porcine intestine. FEBS Lett (1983) 3.12
The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations. Blood (2000) 3.09
Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes. Cell Mol Life Sci (2008) 3.07
Identification and partial characterization of new antigens from simian virus 40-transformed mouse cells. J Virol (1979) 3.04
From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells. Proc Natl Acad Sci U S A (1999) 3.00
Hemichorea-hemiballism: an explanation for MR signal changes. AJNR Am J Neuroradiol (1998) 2.97
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. Proc Natl Acad Sci U S A (2001) 2.91
Human aldehyde dehydrogenase gene family. Eur J Biochem (1998) 2.86
Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol (1994) 2.69
Structural analysis of the X-linked gene encoding human glucose 6-phosphate dehydrogenase. EMBO J (1986) 2.64
Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol (1995) 2.63
Antibacterial peptides from pig intestine: isolation of a mammalian cecropin. Proc Natl Acad Sci U S A (1989) 2.59
A dominant mutant receptor from Arabidopsis confers ethylene insensitivity in heterologous plants. Nat Biotechnol (1997) 2.58
Prevalence of primary and secondary hypertension: studies in a random population sample. Br Med J (1976) 2.57
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor. Proc Natl Acad Sci U S A (2001) 2.45
Expression of the precore region of an avian hepatitis B virus is not required for viral replication. J Virol (1987) 2.42
Antibodies against a synthetic peptide identify the Epstein-Barr virus-determined nuclear antigen. Proc Natl Acad Sci U S A (1984) 2.40
PICK1 targets activated protein kinase Calpha to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. J Neurosci (2001) 2.39
Aldehyde dehydrogenase from human liver. Primary structure of the cytoplasmic isoenzyme. Eur J Biochem (1984) 2.36
Intermediates in adenovirus assembly. J Virol (1976) 2.26
The distance to community medical care and the likelihood of hospitalization: is closer always better? Am J Public Health (1997) 2.21
Structure of the IgG-binding regions of streptococcal protein G. EMBO J (1986) 2.20
Validation of the functional assessment of multiple sclerosis quality of life instrument. Neurology (1996) 2.20
Developmental regulation of the gibberellin biosynthetic gene GA1 in Arabidopsis thaliana. Plant J (1997) 2.18
Characteristics of alcohol/polyol dehydrogenases. The zinc-containing long-chain alcohol dehydrogenases. Eur J Biochem (1987) 2.17
Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue. Biochem Biophys Res Commun (1979) 2.16
Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity. Proc Natl Acad Sci U S A (1992) 2.14
Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J Immunol (1996) 2.13
Purification and biochemical characterization of the Epstein-Barr virus-determined nuclear antigen and an associated protein with a 53,000-dalton subunit. J Virol (1980) 2.07
Mutations that impair a posttranscriptional step in expression of HLA-A and -B antigens. Proc Natl Acad Sci U S A (1985) 2.05
N-terminally extended somatostatin: the primary structure of somatostatin-28. FEBS Lett (1980) 2.04
Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary. Neuron (1991) 2.02
Structural analyses of mutant and wild-type alcohol dehydrogenases from drosophila melanogaster. Eur J Biochem (1976) 2.00
Induction of the TRPM-2 gene in cells undergoing programmed death. Mol Cell Biol (1989) 1.98
The RING finger/B-box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans. Genes Dev (1999) 1.97
Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem (1991) 1.95
Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proc Natl Acad Sci U S A (1990) 1.94
Acetylation of Protein N-terminal amino groups structural observations on alpha-amino acetylated proteins. J Theor Biol (1975) 1.93
Structures of N-terminally acetylated proteins. Eur J Biochem (1985) 1.92
Specific binding of proinsulin C-peptide to human cell membranes. Proc Natl Acad Sci U S A (1999) 1.91
LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. Immunity (1997) 1.85
NMR structure of the death domain of the p75 neurotrophin receptor. EMBO J (1997) 1.84
Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14. Oncogene (1993) 1.83
Crystal structure of NAD(+)-dependent DNA ligase: modular architecture and functional implications. EMBO J (2000) 1.78
Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate. J Biol Chem (1999) 1.76
Twisted gastrulation can function as a BMP antagonist. Nature (2001) 1.75
CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes. Immunity (1996) 1.75
Alcohol and polyol dehydrogenases are both divided into two protein types, and structural properties cross-relate the different enzyme activities within each type. Proc Natl Acad Sci U S A (1981) 1.74
Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol (1995) 1.73
Relationship among Tau antigens isolated from various lines of simian virus 40-transformed cells. J Virol (1980) 1.72
The primary structure of alcohol dehydrogenase from Drosophila lebanonensis. Extensive variation within insect 'short-chain' alcohol dehydrogenase lacking zinc. Eur J Biochem (1989) 1.70
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J Biol Chem (1984) 1.70
Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science (1995) 1.70
Structural homologies between prealbumin, gastrointestinal prohormones and other proteins. Nature (1981) 1.69
Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor. J Biol Chem (1999) 1.69
Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts. Neuron (2001) 1.69
cDNA sequences of human glucose 6-phosphate dehydrogenase cloned in pBR322. Nature (1981) 1.69
Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas. FEBS Lett (1999) 1.68
Two hydrophobic low-molecular-mass protein fractions of pulmonary surfactant. Characterization and biophysical activity. Eur J Biochem (1987) 1.67
Purification of Epstein-Barr virus DNA polymerase from P3HR-1 cells. J Virol (1985) 1.66
Gene expression of rat and human microsomal glutathione S-transferases. J Biol Chem (1988) 1.66
Multiple mRNA species for the precursor to an adenovirus-encoded glycoprotein: identification and structure of the signal sequence. Proc Natl Acad Sci U S A (1980) 1.66
Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations. Eur J Biochem (1985) 1.65
The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells. J Exp Med (1993) 1.62
The Arabidopsis eer1 mutant has enhanced ethylene responses in the hypocotyl and stem. Plant Physiol (2001) 1.58
The two major isozymes of yeast alcohol dehydrogenase. Eur J Biochem (1979) 1.57
A super-family of medium-chain dehydrogenases/reductases (MDR). Sub-lines including zeta-crystallin, alcohol and polyol dehydrogenases, quinone oxidoreductase enoyl reductases, VAT-1 and other proteins. Eur J Biochem (1994) 1.56
Subunit conformation of yeast alcohol dehydrogenase. J Biol Chem (1978) 1.54
Diabetes mellitus and raised serum triglyceride concentration in treated hypertension--are they of prognostic importance? Observational study. BMJ (1996) 1.54
Initial clinical experience with ICI 141,292 (Visacor), a new selective beta 1-adrenoceptor blocker with ISA--a multicentre trial in 59 patients. Br J Clin Pharmacol (1984) 1.53
Differential expression of epidermal growth factor-related proteins in human colorectal tumors. Proc Natl Acad Sci U S A (1991) 1.52
Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. J Biol Chem (2000) 1.52
Medium- and short-chain dehydrogenase/reductase gene and protein families : the MDR superfamily. Cell Mol Life Sci (2008) 1.52
Prolongation of survival in metastatic melanoma after active specific immunotherapy with a new polyvalent melanoma vaccine. Ann Surg (1992) 1.50
Escherichia coli ferredoxin NADP+ reductase: activation of E. coli anaerobic ribonucleotide reduction, cloning of the gene (fpr), and overexpression of the protein. J Bacteriol (1993) 1.49
Smad5 induces ventral fates in Xenopus embryo. Dev Biol (1997) 1.49
Reflex sympathetic activation induces acute insulin resistance in the human forearm. Hypertension (1993) 1.48
Androgen receptor interacts with the positive elongation factor P-TEFb and enhances the efficiency of transcriptional elongation. J Biol Chem (2000) 1.48
Antibodies against synthetic peptides react with the second Epstein-Barr virus-associated nuclear antigen. EMBO J (1985) 1.48
Identification, characterization, and purification of two mammalian stress proteins present in mitochondria, grp 75, a member of the hsp 70 family and hsp 58, a homolog of the bacterial groEL protein. J Biol Chem (1989) 1.47