Published in Mol Cell Biol on November 01, 2001
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J (2009) 3.11
A comprehensive map of the toll-like receptor signaling network. Mol Syst Biol (2006) 2.89
A divergent external loop confers antagonistic activity on floral regulators FT and TFL1. EMBO J (2006) 2.29
A single amino acid converts a repressor to an activator of flowering. Proc Natl Acad Sci U S A (2005) 2.25
Tomato SP-interacting proteins define a conserved signaling system that regulates shoot architecture and flowering. Plant Cell (2001) 2.11
Transcriptional profiling of the LPS induced NF-kappaB response in macrophages. BMC Immunol (2007) 1.71
Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Mol Cell (2006) 1.71
TERMINAL FLOWER1 is a mobile signal controlling Arabidopsis architecture. Plant Cell (2007) 1.65
Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J (2011) 1.60
Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention. J Exp Clin Cancer Res (2014) 1.39
Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Curr Cancer Drug Targets (2011) 1.33
NF-κB inducing kinase: a key regulator in the immune system and in cancer. Cytokine Growth Factor Rev (2010) 1.28
The Role of B-RAF Mutations in Melanoma and the Induction of EMT via Dysregulation of the NF-κB/Snail/RKIP/PTEN Circuit. Genes Cancer (2010) 1.14
Mutant human cells with constitutive activation of NF-kappaB. Proc Natl Acad Sci U S A (2003) 1.14
Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer. Cancer Res (2009) 1.11
IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation. Proc Natl Acad Sci U S A (2004) 1.11
The dynamic control of signal transduction networks in cancer cells. Nat Rev Cancer (2015) 1.09
NF-κB and cancer: a paradigm of Yin-Yang. Am J Cancer Res (2010) 1.08
Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells. Nucleic Acids Res (2006) 1.07
Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae. Eukaryot Cell (2004) 1.04
Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction. Cell Signal (2007) 1.04
Mechanisms of nitric oxide-mediated inhibition of EMT in cancer: inhibition of the metastasis-inducer Snail and induction of the metastasis-suppressor RKIP. Cell Cycle (2010) 1.04
Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas. PLoS One (2012) 1.04
A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation. Mol Cell Biol (2003) 1.03
Targeting nuclear factor-kappa B to overcome resistance to chemotherapy. Front Oncol (2013) 1.01
A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph. Proc Natl Acad Sci U S A (2004) 1.00
Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism. Mol Cell Biol (2008) 0.98
The oxazolidinone derivative locostatin induces cytokine appeasement. J Immunol (2009) 0.97
Raf kinase inhibitory protein knockout mice: expression in the brain and olfaction deficit. Brain Res Bull (2006) 0.97
Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model. Oncogene (2012) 0.95
Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer. PLoS One (2014) 0.95
Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival. BMC Cancer (2011) 0.94
PPAR signaling pathway and cancer-related proteins are involved in celiac disease-associated tissue damage. Mol Med (2010) 0.94
Raf kinase inhibitor RKIP inhibits MDA-9/syntenin-mediated metastasis in melanoma. Cancer Res (2012) 0.93
Raf Kinase Inhibitory Protein protects cells against locostatin-mediated inhibition of migration. PLoS One (2009) 0.91
Loss of RKIP expression is associated with poor survival in GISTs. Virchows Arch (2009) 0.89
RKIP inhibition in cervical cancer is associated with higher tumor aggressive behavior and resistance to cisplatin therapy. PLoS One (2013) 0.89
RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients. BMC Cancer (2013) 0.88
RKIP-mediated chemo-immunosensitization of resistant cancer cells via disruption of the NF-κB/Snail/YY1/RKIP resistance-driver loop. Crit Rev Oncog (2014) 0.88
YbcL of uropathogenic Escherichia coli suppresses transepithelial neutrophil migration. Infect Immun (2012) 0.88
Safety, efficacy, pharmacokinetics, and pharmacodynamics of the combination of sorafenib and tanespimycin. Clin Cancer Res (2010) 0.88
A new model for raf kinase inhibitory protein induced chemotherapeutic resistance. PLoS One (2012) 0.87
Identification of novel metastasis suppressor signaling pathways for breast cancer. Cell Cycle (2012) 0.86
Genetic variants in RKIP are associated with clear cell renal cell carcinoma risk in a Chinese population. PLoS One (2014) 0.86
Raf kinase inhibitor protein (RKIP) dimer formation controls its target switch from Raf1 to G protein-coupled receptor kinase (GRK) 2. J Biol Chem (2012) 0.85
Reduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signaling. Oncotarget (2015) 0.85
Dihydroartemisinin induces apoptosis of cervical cancer cells via upregulation of RKIP and downregulation of bcl-2. Cancer Biol Ther (2013) 0.85
Regulation of RKIP binding to the N-region of the Raf-1 kinase. FEBS Lett (2006) 0.84
Raf kinase inhibitor protein suppresses nuclear factor-κB-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression. Cancer Lett (2010) 0.84
Low RKIP expression associates with poor prognosis in bladder cancer patients. Virchows Arch (2013) 0.84
Dual roles of nitric oxide in the regulation of tumor cell response and resistance to photodynamic therapy. Redox Biol (2015) 0.83
RAF-kinase inhibitor protein (RKIP) downregulation in esophageal cancer and its metastases. Clin Exp Metastasis (2012) 0.83
Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity. Oncotarget (2016) 0.82
Phosphatidylethanolamine binding protein 1 in vacular endothelial cell autophagy and atherosclerosis. J Physiol (2013) 0.82
Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages. Cancer Res (2015) 0.82
Role of Raf Kinase Inhibitor Protein in Pathophysiology of Prostate Cancer. For Immunopathol Dis Therap (2011) 0.82
Cilia movement regulates expression of the Raf-1 kinase inhibitor protein. Am J Physiol Renal Physiol (2011) 0.81
RKIP contributes to IFN-γ synthesis by CD8+ T cells after serial TCR triggering in systemic inflammatory response syndrome. J Immunol (2013) 0.81
Expression of Raf-1 kinase inhibitory protein in carcinoma of the ampulla of Vater. Virchows Arch (2011) 0.81
Ligand binding study of human PEBP1/RKIP: interaction with nucleotides and Raf-1 peptides evidenced by NMR and mass spectrometry. PLoS One (2012) 0.81
Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma. Oncotarget (2014) 0.80
Raf kinase inhibitor protein inhibits cholangiocarcinoma cell metastasis by downregulating matrix metalloproteinase 9 and upregulating tissue inhibitor of metalloproteinase 4 expression. Oncol Lett (2014) 0.80
Regulation of RKIP function by Helicobacter pylori in gastric cancer. PLoS One (2012) 0.80
Dengue-2 structural proteins associate with human proteins to produce a coagulation and innate immune response biased interactome. BMC Infect Dis (2011) 0.80
Proteomic analysis of Oesophagostomum dentatum (Nematoda) during larval transition, and the effects of hydrolase inhibitors on development. PLoS One (2013) 0.80
The role of Raf kinase inhibitor protein in rheumatoid fibroblast-like synoviocytes invasiveness and cytokine and matrix metalloproteinase expression. Inflammation (2012) 0.79
RKIP regulates MAP kinase signaling in cells with defective B-Raf activity. Cell Signal (2013) 0.79
Phosphatidylenthanolamine Binding Protein aka Raf Kinase Inhibitor Protein: A Brief History of Its Discovery and the Remarkable Diversity of Biological Functions. For Immunopathol Dis Therap (2011) 0.78
Roles Each of Snail, Yin Yang 1 and RKIP in the Regulation of Tumor Cells Chemo-immuno-resistance to Apoptosis. For Immunopathol Dis Therap (2013) 0.78
TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer. Int J Cancer (2010) 0.78
Proteomic analysis of peripheral T lymphocytes, suitable circulating biosensors of strictly related diseases. Clin Exp Immunol (2007) 0.78
Interactions of RKIP with inflammatory signaling pathways. Crit Rev Oncog (2014) 0.77
Protein kinase C-mediated phosphorylation of RKIP regulates inhibition of Na-alanine cotransport by leukotriene D(4) in intestinal epithelial cells. Am J Physiol Cell Physiol (2014) 0.77
Raf kinase inhibitory protein (RKIP): functional pleiotropy in the mammalian brain. Crit Rev Oncog (2014) 0.77
Role of Raf-kinase inhibitor protein in colorectal cancer and its regulation by hydroxycamptothecine. J Biomed Sci (2015) 0.77
Expression of RKIP, E-cadherin and NF-kB p65 in esophageal squamous cell carcinoma and their correlations. Int J Clin Exp Pathol (2015) 0.77
Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation. J Biol Chem (2009) 0.77
The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.76
The proteomic response in glioblastoma in young patients. J Neurooncol (2014) 0.76
Therapeutic targeting of the inflammome. Biochem Pharmacol (2014) 0.76
Integrated modulation of phorbol ester-induced Raf activation in EL4 lymphoma cells. Cell Signal (2009) 0.76
Inhibition of Epithelial-to-Mesenchymal Transition (EMT) in Cancer by Nitric Oxide: Pivotal Roles of Nitrosylation of NF-κB, YY1 and Snail. For Immunopathol Dis Therap (2012) 0.76
Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP. Cancer Res (2016) 0.76
Raf kinase inhibitor protein regulates oxygen-glucose deprivation-induced PC12 cells apoptosis through the NF-κB and ERK pathways. J Clin Biochem Nutr (2016) 0.75
"Freeze, Don't Move": How to Arrest a Suspect in Heart Failure - A Review on Available GRK2 Inhibitors. Front Cardiovasc Med (2016) 0.75
Extracellular vesicle-mediated phenotype switching in malignant and non-malignant colon cells. BMC Cancer (2015) 0.75
The draft genome of whitefly Bemisia tabaci MEAM1, a global crop pest, provides novel insights into virus transmission, host adaptation, and insecticide resistance. BMC Biol (2016) 0.75
Reduction of Raf Kinase Inhibitor Protein Expression is Associated with Lymph Node Metastasis in Resectable Non-small Cell Lung Cancer. Open Respir Med J (2012) 0.75
Promoter methylation and expression of Raf kinase inhibitory protein in esophageal squamous cell carcinoma. Oncol Lett (2017) 0.75
RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13. PLoS One (2015) 0.75
RKIP suppresses the proliferation and invasion ofchoriocarcinoma cells through inhibiting the MAPK signaling pathway. Int J Clin Exp Med (2015) 0.75
RKIP structure drives its function: a three-state model for regulation of RKIP. Crit Rev Oncog (2014) 0.75
PEBP1, a RAF kinase inhibitory protein, negatively regulates starvation-induced autophagy by direct interaction with LC3. Autophagy (2016) 0.75
Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget (2016) 0.75
Clinicopathological features and prognostic implications of Raf kinase inhibitor protein downregulation in tongue squamous cell carcinoma. Oncol Lett (2015) 0.75
RKIP and TBK1 form a positive feedback loop to promote type I interferon production in innate immunity. EMBO J (2016) 0.75
Inverse association between Bmi-1 and RKIP affecting clinical outcome of gastric cancer and revealing the potential molecular mechanisms underlying tumor metastasis and chemotherapy resistance. Gastric Cancer (2015) 0.75
Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein. Oncotarget (2017) 0.75
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