Published in J Immunol on October 15, 2001
Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol (2010) 11.80
Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol (2003) 2.93
Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity (2007) 2.88
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci U S A (2004) 2.55
Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity (2011) 2.53
The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells. Nat Immunol (2010) 1.72
Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses. J Exp Med (2005) 1.66
An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation. Int Immunol (2011) 1.48
Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function. J Immunol (2007) 1.41
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol (2011) 1.41
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat Commun (2012) 1.39
Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB. EMBO J (2002) 1.31
NFIL3/E4BP4 controls type 2 T helper cell cytokine expression. EMBO J (2011) 1.26
Posttranscriptional regulation of IL-13 in T cells: role of the RNA-binding protein HuR. J Allergy Clin Immunol (2008) 1.08
New drugs targeting Th2 lymphocytes in asthma. J Occup Med Toxicol (2008) 1.03
Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice. Blood (2005) 1.01
Smad3 -signalling and Th2 cytokines in normal mouse airways and in a mouse model of asthma. Int J Biol Sci (2007) 1.00
Hierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cells. J Immunol (2011) 0.98
'All things considered': transcriptional regulation of T helper type 2 cell differentiation from precursor to effector activation. Immunology (2013) 0.94
Epigenetic control of cytokine gene expression: regulation of the TNF/LT locus and T helper cell differentiation. Adv Immunol (2013) 0.94
T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production. Cytokine (2015) 0.92
NF45 and NF90 regulate HS4-dependent interleukin-13 transcription in T cells. J Biol Chem (2010) 0.91
The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo. Clin Exp Immunol (2004) 0.89
c-Myb and GATA-3 cooperatively regulate IL-13 expression via conserved GATA-3 response element and recruit mixed lineage leukemia (MLL) for histone modification of the IL-13 locus. J Immunol (2011) 0.87
Transcriptional regulation of Th2 cell differentiation. Immunol Cell Biol (2010) 0.86
Hybrid cell vaccination resolves Leishmania donovani infection by eliciting a strong CD8+ cytotoxic T-lymphocyte response with concomitant suppression of interleukin-10 (IL-10) but not IL-4 or IL-13. Infect Immun (2007) 0.86
Phylogenetic and functional analysis identifies Ets-1 as a novel regulator of the Th2 cytokine gene locus. J Immunol (2009) 0.85
Genomics and proteomics of allergic disease. Immunology (2002) 0.85
Characterization of a novel PMA-inducible pathway of interleukin-13 gene expression in T cells. Immunology (2006) 0.85
The differential expression of IL-4 and IL-13 and its impact on type-2 immunity. Cytokine (2015) 0.84
Downstream targets of GATA3 in the vestibular sensory organs of the inner ear. Dev Dyn (2009) 0.83
Animal models of chronic experimental asthma - strategies for the identification of new therapeutic targets. J Occup Med Toxicol (2008) 0.83
Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation. Mucosal Immunol (2015) 0.80
Reduced CCR4, interleukin-13 and GATA-3 up-regulation in response to type 2 cytokines of cord blood T lymphocytes in infants at genetic risk of type 1 diabetes. Immunology (2007) 0.77
Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells. PLoS One (2014) 0.76
Transcriptional regulation of T helper type 2 differentiation. Immunology (2014) 0.76
TNF superfamily member 13, APRIL, inhibits allergic lung inflammation. Eur J Immunol (2010) 0.76
The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program. Nat Immunol (2017) 0.75
Qualitative differences in brain-infiltrating T cells are associated with a fatal outcome in mice infected with Japanese encephalitis virus. Arch Virol (2015) 0.75
The Cellular and Molecular Mechanism of Radiation-Induced Lung Injury. Med Sci Monit (2017) 0.75
The sequence of the human genome. Science (2001) 101.55
Smoking cessation with and without assistance: a population-based analysis. Am J Prev Med (2000) 3.92
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity (1999) 3.61
Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem (2000) 3.34
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem (2001) 3.24
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
Nanostructured high-strength molybdenum alloys with unprecedented tensile ductility. Nat Mater (2013) 2.90
Molecular characterization and transcriptional analysis of type 8 capsule genes in Staphylococcus aureus. J Bacteriol (1997) 2.58
cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1. Mol Cell Biol (1992) 2.55
Clinical manifestations and diagnosis of acute pyrethroid poisoning. Arch Toxicol (1989) 2.50
The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions. Cell (2000) 2.41
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J (2001) 2.32
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity (1996) 2.24
The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity (1998) 2.13
Predictors of smoking cessation in U.S. adolescents. Am J Prev Med (1999) 2.09
IMPACT trial results should not change current standard of care of 100 days for cytomegalovirus prophylaxis. Am J Transplant (2010) 2.05
Evolutionarily conserved Ets family members display distinct DNA binding specificities. J Exp Med (1992) 2.04
Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation. EMBO J (1997) 2.02
Further characterization of endometrial integrins during the menstrual cycle and in pregnancy. Fertil Steril (1994) 1.99
Smoking, air pollution, and the high rates of lung cancer in Shenyang, China. J Natl Cancer Inst (1989) 1.99
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
Indoor radon and lung cancer in China. J Natl Cancer Inst (1990) 1.95
Pseudomonas aeruginosa ExoS and ExoT. Rev Physiol Biochem Pharmacol (2004) 1.91
Reverse transcriptase in a clinical strain of Escherichia coli: production of branched RNA-linked msDNA. Science (1989) 1.89
A phospholipid acts as a chaperone in assembly of a membrane transport protein. J Biol Chem (1996) 1.89
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J Biol Chem (1996) 1.87
Effects of pyrethroid insecticides on subjects engaged in packaging pyrethroids. Br J Ind Med (1988) 1.87
Local anesthesia for functional endoscopic sinus surgery employing small volumes of epinephrine-containing solutions of lidocaine produces profound hypotension. Acta Anaesthesiol Scand (2005) 1.77
Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J Biol Chem (1995) 1.75
Survival and function of bioengineered cardiac grafts. Circulation (1999) 1.72
Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. Proc Natl Acad Sci U S A (1998) 1.71
ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. J Cell Biol (2000) 1.66
High-dose/activation-associated tolerance: a mechanism for allograft tolerance. Transplantation (1997) 1.65
Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection. J Immunol (1997) 1.62
A short course of methylprednisolone immunosuppression inhibits both rejection and spontaneous acceptance of rat liver allografts. Transplantation (2001) 1.61
Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-negative Chinese carriers. Hepatology (2001) 1.61
The Bacillus subtilis DinR binding site: redefinition of the consensus sequence. J Bacteriol (1998) 1.61
Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc Natl Acad Sci U S A (1999) 1.60
Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway. Mol Cell Biol (1998) 1.59
Endometrial progesterone receptors and markers of uterine receptivity in the window of implantation. Fertil Steril (1996) 1.58
Type 1 and type 2 cytokine regulation of macrophage endocytosis: differential activation by IL-4/IL-13 as opposed to IFN-gamma or IL-10. J Immunol (1999) 1.58
Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer. Oncogene (2011) 1.50
Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members. Endocrinology (2000) 1.50
Hepatic radioembolization with Yttrium-90 glass microspheres for treatment of primary liver cancer. Chin Med J (Engl) (1999) 1.48
Real-time measurements of DNA hybridization on microparticles with fluorescence resonance energy transfer. Anal Biochem (1999) 1.47
The dystrobrevin-binding protein 1 gene: features and networks. Mol Psychiatry (2008) 1.47
ROG, repressor of GATA, regulates the expression of cytokine genes. Immunity (2000) 1.46
Promising thermoelectric properties of commercial PEDOT:PSS materials and their bi2Te3 powder composites. ACS Appl Mater Interfaces (2010) 1.45
Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J Neurosci (2000) 1.43
Arabidopsis RelA/SpoT homologs implicate (p)ppGpp in plant signaling. Proc Natl Acad Sci U S A (2000) 1.42
Loss of endothelial surface expression of E-selectin in a patient with recurrent infections. Blood (1999) 1.42
Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radic Biol Med (2005) 1.42
A hemisphere array for non-invasive ultrasound brain therapy and surgery. Phys Med Biol (2000) 1.40
Purinergic inhibition of the epithelial Na+ transport via hydrolysis of PIP2. FASEB J (2004) 1.40
Endoscopic versus operative gastrostomy: final results of a prospective randomized trial. Gastrointest Endosc (1990) 1.39
Effect of liver transplantation on islet allografts: up-regulation of Fas ligand and apoptosis of T lymphocytes are associated with islet graft tolerance. Transplantation (2001) 1.38
Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease. Infect Immun (1994) 1.38
Main neurodevelopmental study of Seychellois children following in utero exposure to methylmercury from a maternal fish diet: outcome at six months. Neurotoxicology (1995) 1.37
SZGR: a comprehensive schizophrenia gene resource. Mol Psychiatry (2010) 1.36
Where is the sun? Nat Neurosci (1998) 1.36
Transcription activation by the human estrogen receptor subtype beta (ER beta) studied with ER beta and ER alpha receptor chimeras. Endocrinology (1998) 1.36
Efficient extraction and partial purification of the polyribosome-associated stem-loop binding protein bound to the 3' end of histone mRNA. Biochemistry (1996) 1.35
The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner. J Biol Chem (1997) 1.35
Enhancement of human immunodeficiency virus type 1-specific CD4 and CD8 T cell responses in chronically infected persons after temporary treatment interruption. J Infect Dis (2000) 1.33
Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases. J Biol Chem (2000) 1.31
Inhibition of IL-12 production in human monocyte-derived macrophages by TNF. J Immunol (2000) 1.30
Estrogen receptors: selective ligands, partners, and distinctive pharmacology. Recent Prog Horm Res (2000) 1.29
Antibodies against the first Ig-like domain of human platelet endothelial cell adhesion molecule-1 (PECAM-1) that inhibit PECAM-1-dependent homophilic adhesion block in vivo neutrophil recruitment. J Immunol (2000) 1.29
IL-13 and IFN-gamma secretion by activated T cells in HIV-1 infection associated with viral suppression and a lack of disease progression. J Immunol (1999) 1.29
IFN-gamma and TNF-alpha induce redistribution of PECAM-1 (CD31) on human endothelial cells. J Immunol (1995) 1.28
Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle. Osteoarthritis Cartilage (2005) 1.27
Integrins as markers of uterine receptivity in women with primary unexplained infertility. Fertil Steril (1995) 1.27
Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice. J Biol Chem (2000) 1.27
RNA aptamers interfering with nucleophosmin oligomerization induce apoptosis of cancer cells. Oncogene (2009) 1.27
Mutational analysis of slyD, an Escherichia coli gene encoding a protein of the FKBP immunophilin family. Mol Microbiol (1997) 1.25
Management of alopecia areata. BMJ (2010) 1.25
Specific recognition of thymic self-peptides induces the positive selection of cytotoxic T lymphocytes. Immunity (1997) 1.24
Kinetics of serological responses in influenza A(H7N9)-infected patients correlate with clinical outcome in China, 2013. Euro Surveill (2013) 1.24
Angiotensin II induces nuclear factor (NF)-kappaB1 isoforms to bind the angiotensinogen gene acute-phase response element: a stimulus-specific pathway for NF-kappaB activation. Mol Endocrinol (2000) 1.24
Genetic variation in the COX-2 gene and the association with prostate cancer risk. Int J Cancer (2006) 1.23
Coupled B-snake grids and constrained thin-plate splines for analysis of 2-D tissue deformations from tagged MRI. IEEE Trans Med Imaging (1998) 1.22
The Seychelles child development study on neurodevelopmental outcomes in children following in utero exposure to methylmercury from a maternal fish diet: background and demographics. Neurotoxicology (1995) 1.22
Chitosan-glycerol phosphate/blood implants elicit hyaline cartilage repair integrated with porous subchondral bone in microdrilled rabbit defects. Osteoarthritis Cartilage (2006) 1.21
Conserved sequence preference in DNA binding among recombination proteins: an effect of ssDNA secondary structure. Nucleic Acids Res (1999) 1.21
Economic growth and suicide rate changes: a case in China from 1982 to 2005. Eur Psychiatry (2009) 1.21
Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression. Exp Neurol (1994) 1.20
Differential methylation of the TRPA1 promoter in pain sensitivity. Nat Commun (2014) 1.19
Chitosan-glycerol phosphate/blood implants increase cell recruitment, transient vascularization and subchondral bone remodeling in drilled cartilage defects. Osteoarthritis Cartilage (2006) 1.18
Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1. Mol Cell Biol (2001) 1.18
Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice. Nat Biotechnol (2000) 1.18
The second (main) phase of an open, randomised, multicentre study to investigate the effectiveness of an intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT2). Int J Stroke (2010) 1.17
Effects of prenatal methylmercury exposure from a high fish diet on developmental milestones in the Seychelles Child Development Study. Neurotoxicology (1997) 1.17
Synthesis and crystal structure of some transition metal complexes with a novel bis-Schiff base ligand and their antitumor activities. Eur J Med Chem (2006) 1.17
Overexpression of matrix metalloproteinase-8 and -9 in bronchiectatic airways in vivo. Eur Respir J (2002) 1.16
Articular cartilage metabolism in patients with Kashin-Beck Disease: an endemic osteoarthropathy in China. Osteoarthritis Cartilage (2007) 1.15
Bacterial plasmolysis as a physical indicator of viability. Appl Environ Microbiol (1996) 1.15
Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1). J Biol Chem (1995) 1.15