Published in Glia on November 01, 2001
Role of microglia in central nervous system infections. Clin Microbiol Rev (2004) 2.69
Development, maintenance and disruption of the blood-brain barrier. Nat Med (2013) 2.62
Cellular reservoirs of HIV-1 and their role in viral persistence. Curr HIV Res (2008) 2.40
Dual roles for perivascular macrophages in immune-to-brain signaling. Neuron (2010) 2.24
CD163 identifies perivascular macrophages in normal and viral encephalitic brains and potential precursors to perivascular macrophages in blood. Am J Pathol (2006) 1.92
Induction of pathogenic sets of genes in macrophages and neurons in NeuroAIDS. Am J Pathol (2003) 1.87
Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS. J Immunol (2009) 1.85
Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy. Proc Natl Acad Sci U S A (2009) 1.83
Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS. J Clin Invest (2005) 1.78
Emerging role of the cannabinoid receptor CB2 in immune regulation: therapeutic prospects for neuroinflammation. Expert Rev Mol Med (2009) 1.44
Ontogeny and homeostasis of CNS myeloid cells. Nat Immunol (2017) 1.44
Spinal microglial and perivascular cell cannabinoid receptor type 2 activation reduces behavioral hypersensitivity without tolerance after peripheral nerve injury. Anesthesiology (2008) 1.39
Curing HIV: Pharmacologic approaches to target HIV-1 latency. Annu Rev Pharmacol Toxicol (2011) 1.38
Vascular inflammatory cells in hypertension. Front Physiol (2012) 1.37
Macrophage/microglial accumulation and proliferating cell nuclear antigen expression in the central nervous system in human immunodeficiency virus encephalopathy. Am J Pathol (2004) 1.28
The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity. J Immunol (2010) 1.26
HIV-1 infection of bone marrow hematopoietic progenitor cells and their role in trafficking and viral dissemination. PLoS Pathog (2008) 1.22
Loss of neuronal integrity during progressive HIV-1 infection of humanized mice. J Neurosci (2011) 1.22
Drowning stars: reassessing the role of astrocytes in brain edema. Trends Neurosci (2014) 1.13
Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS. PLoS One (2010) 1.07
Correlation of acute humoral response with brain virus burden and survival time in pig-tailed macaques infected with the neurovirulent simian immunodeficiency virus SIVsmmFGb. Am J Pathol (2004) 1.05
Scanning electron microscopy of the neuropathology of murine cerebral malaria. Malar J (2006) 1.04
Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates. Am J Pathol (2009) 1.01
Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains. J Virol (2002) 1.00
The blood-brain barrier. Cold Spring Harb Perspect Biol (2015) 1.00
Acquired immunodeficiency syndrome and the blood-brain barrier. J Neurovirol (2009) 1.00
Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease. Epilepsia (2012) 0.98
T cells specifically targeted to amyloid plaques enhance plaque clearance in a mouse model of Alzheimer's disease. PLoS One (2010) 0.96
Brain dendritic cells: biology and pathology. Acta Neuropathol (2012) 0.96
The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses. Cerebrospinal Fluid Res (2006) 0.93
Impact of short-term combined antiretroviral therapy on brain virus burden in simian immunodeficiency virus-infected and CD8+ lymphocyte-depleted rhesus macaques. Am J Pathol (2010) 0.92
Anti-α4 antibody treatment blocks virus traffic to the brain and gut early, and stabilizes CNS injury late in infection. PLoS Pathog (2014) 0.92
Biomarkers of neurological status in HIV infection: a 3-year study. Proteomics Clin Appl (2010) 0.92
Systemic lipopolysaccharide compromises the blood-labyrinth barrier and increases entry of serum fluorescein into the perilymph. J Assoc Res Otolaryngol (2014) 0.92
In vivo dynamics of innate immune sentinels in the CNS. Intravital (2012) 0.92
Human blood-derived macrophages enhance barrier function of cultured primary bovine and human brain capillary endothelial cells. J Physiol (2003) 0.89
Models and mechanisms for hippocampal dysfunction in obesity and diabetes. Neuroscience (2015) 0.89
Senescence-accelerated Mice (SAMs) as a Model for Brain Aging and Immunosenescence. Aging Dis (2011) 0.88
Scavenger receptor class B type I (SR-BI) regulates perivascular macrophages and modifies amyloid pathology in an Alzheimer mouse model. Proc Natl Acad Sci U S A (2010) 0.88
SIV encephalitis lesions are composed of CD163(+) macrophages present in the central nervous system during early SIV infection and SIV-positive macrophages recruited terminally with AIDS. Am J Pathol (2015) 0.87
CD8+ lymphocyte depletion without SIV infection does not produce metabolic changes or pathological abnormalities in the rhesus macaque brain. J Med Primatol (2011) 0.87
HIV-1 Nef in macrophage-mediated disease pathogenesis. Int Rev Immunol (2012) 0.86
Development and characterization of positively selected brain-adapted SIV. Virol J (2005) 0.84
Disease-associated prion protein in vessel walls. Am J Pathol (2002) 0.83
Systemic and brain macrophage infections in relation to the development of simian immunodeficiency virus encephalitis. J Virol (2008) 0.82
Neuropathogenic SIVsmmFGb genetic diversity and selection-induced tissue-specific compartmentalization during chronic infection and temporal evolution of viral genes in lymphoid tissues and regions of the central nervous system. AIDS Res Hum Retroviruses (2010) 0.81
HIV-associated neuropathogenesis: a systems biology perspective for modeling and therapy. Biosystems (2014) 0.80
Experimental Cerebral Malaria Spreads along the Rostral Migratory Stream. PLoS Pathog (2016) 0.79
Beneficial Effects of Cocoa in Perivascular Mato Cells of Cerebral Arterioles in SHR-SP (Izm) Rats. J Clin Biochem Nutr (2009) 0.78
The Role of Cell-Penetrating Peptide and Transferrin on Enhanced Delivery of Drug to Brain. Int J Mol Sci (2016) 0.78
Traffic-related air pollution and brain development. AIMS Environ Sci (2015) 0.78
Effects of maternal exposure to ultrafine carbon black on brain perivascular macrophages and surrounding astrocytes in offspring mice. PLoS One (2014) 0.77
A confocal and electron microscopic comparison of interferon beta-induced changes in vesicular stomatitis virus infection of neuroblastoma and nonneuronal cells. DNA Cell Biol (2010) 0.77
Localization of lipocaline-type prostaglandin D synthase in rat brain: immunoelectron microscopic study. Histochem Cell Biol (2004) 0.76
Early Intravenous Delivery of Human Brain Stromal Cells Modulates Systemic Inflammation and Leads to Vasoprotection in Traumatic Spinal Cord Injury. Stem Cells Transl Med (2016) 0.76
Dose-dependent induction of astrocyte activation and reactive astrogliosis in mouse brain following maternal exposure to carbon black nanoparticle. Part Fibre Toxicol (2017) 0.76
Global gray and white matter metabolic changes after simian immunodeficiency virus infection in CD8-depleted rhesus macaques: proton MRS imaging at 3 T. NMR Biomed (2013) 0.76
MIP-3β/CCL19 is associated with the intrathecal invasion of mononuclear cells in neuroinflammatory and non-neuroinflammatory CNS diseases in dogs. BMC Vet Res (2014) 0.75
Organ-specific protection mediated by cooperation between vascular and epithelial barriers. Nat Rev Immunol (2017) 0.75
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science (1998) 12.81
Progesterone implants enhance SIV vaginal transmission and early virus load. Nat Med (1996) 5.63
Progression to AIDS in the absence of a gene for vpr or vpx. J Virol (1995) 3.96
Identifying the target cell in primary simian immunodeficiency virus (SIV) infection: highly activated memory CD4(+) T cells are rapidly eliminated in early SIV infection in vivo. J Virol (2000) 3.48
Genital mucosal transmission of simian immunodeficiency virus: animal model for heterosexual transmission of human immunodeficiency virus. J Virol (1989) 3.43
Dynamics of CCR5 expression by CD4(+) T cells in lymphoid tissues during simian immunodeficiency virus infection. J Virol (2000) 3.31
Resistance of neonatal monkeys to live attenuated vaccine strains of simian immunodeficiency virus. Nat Med (1997) 3.11
A herpesvirus of rhesus monkeys related to the human Kaposi's sarcoma-associated herpesvirus. J Virol (1997) 3.10
Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys. Cell (1995) 3.03
HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med (1999) 3.01
Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS. J Exp Med (2001) 2.90
The mucosal immune system: primary target for HIV infection and AIDS. Trends Immunol (2001) 2.38
Characterization of gut-associated lymphoid tissue (GALT) of normal rhesus macaques. Clin Immunol Immunopathol (1997) 1.74
Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis. Am J Pathol (1996) 1.67
Simian immunodeficiency virus encephalitis in rhesus macaques is associated with rapid disease progression. J Neurovirol (1998) 1.65
Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor. Mol Cell Biol (2000) 1.61
Neuroinvasion by simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation. J Neurovirol (1996) 1.50
Reactivation of latent tuberculosis in rhesus macaques by coinfection with simian immunodeficiency virus. J Med Primatol (2011) 1.47
Identification and characterization of Kaposi's sarcoma-associated herpesvirus K8.1 virion glycoprotein. J Virol (1999) 1.42
Experimental infection of rhesus and pig-tailed macaques with macaque rhadinoviruses. J Virol (1999) 1.41
Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus. J Exp Med (1998) 1.39
Identification of an Enterocytozoon bieneusi-like microsporidian parasite in simian-immunodeficiency-virus-inoculated macaques with hepatobiliary disease. Am J Pathol (1997) 1.38
Macaques with rapid disease progression and simian immunodeficiency virus encephalitis have a unique cytokine profile in peripheral lymphoid tissues. J Virol (2001) 1.38
The non-human primate model of tuberculosis. J Med Primatol (2012) 1.37
Monitoring alpha4beta7 integrin expression on circulating CD4+ T cells as a surrogate marker for tracking intestinal CD4+ T-cell loss in SIV infection. Mucosal Immunol (2009) 1.37
The role of upstream U3 sequences in the pathogenesis of simian immunodeficiency virus-induced AIDS in rhesus monkeys. J Virol (1994) 1.36
Elevated vascular cell adhesion molecule-1 in AIDS encephalitis induced by simian immunodeficiency virus. Am J Pathol (1992) 1.32
Origins of simian immunodeficiency virus infection in macaques at the New England Regional Primate Research Center. J Med Primatol (1995) 1.32
Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: implications for the neuropathogenesis of AIDS. J Immunol (1999) 1.31
Emergence and kinetics of simian immunodeficiency virus-specific CD8(+) T cells in the intestines of macaques during primary infection. J Virol (2001) 1.27
IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques. Mucosal Immunol (2012) 1.26
Detection of simian immunodeficiency virus DNA in macrophages from infected rhesus macaques. J Med Primatol (1992) 1.26
Induction of mucosal homing virus-specific CD8(+) T lymphocytes by attenuated simian immunodeficiency virus. J Virol (2000) 1.25
Recombinant simian immunodeficiency virus expressing green fluorescent protein identifies infected cells in rhesus monkeys. AIDS Res Hum Retroviruses (1999) 1.24
Prevention of simian acquired immune deficiency syndrome with a formalin-inactivated type D retrovirus vaccine. J Virol (1986) 1.24
Induction of lymphocyte proliferation and severe gastrointestinal disease in macaques by a nef gene variant SIVmac239. Am J Pathol (1996) 1.22
Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys. Blood (2001) 1.21
Inhibition of intracellular transport of B cell antigen receptor complexes by Kaposi's sarcoma-associated herpesvirus K1. J Exp Med (2000) 1.18
Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis. Am J Pathol (1998) 1.18
Early brain injury in the SIV-macaque model of AIDS. AIDS (2000) 1.17
Early cytokine and chemokine gene expression in lymph nodes of macaques infected with simian immunodeficiency virus is predictive of disease outcome and vaccine efficacy. J Virol (1997) 1.17
Requirements for lymphocyte activation by unusual strains of simian immunodeficiency virus. J Virol (1996) 1.12
Localization of persistent Enterocytozoon bieneusi infection in normal rhesus macaques (Macaca mulatta) to the hepatobiliary tree. J Clin Microbiol (1998) 1.10
Early intrathecal events in rhesus macaques (Macaca mulatta) infected with pathogenic or nonpathogenic molecular clones of simian immunodeficiency virus. Lab Invest (1995) 1.08
The gastrointestinal tract and the pathogenesis of AIDS. AIDS (1998) 1.08
Induction of AIDS by simian immunodeficiency virus lacking NF-kappaB and SP1 binding elements. J Virol (1997) 1.07
Neuropathogenesis of simian immunodeficiency virus infection in macaque monkeys. J Neurovirol (1997) 1.06
Differential effects of simian immunodeficiency virus infection on immune inductive and effector sites in the rectal mucosa of rhesus macaques. Am J Pathol (2000) 1.05
Developmental expression patterns of CCR5 and CXCR4 in the rhesus macaque brain. J Neuroimmunol (2002) 1.03
Enterocytozoon bieneusi as a cause of proliferative serositis in simian immunodeficiency virus-infected immunodeficient macaques (Macaca mulatta). Arch Pathol Lab Med (2000) 1.02
Evidence of horizontal transmission of Pneumocystis carinii pneumonia in simian immunodeficiency virus-infected rhesus macaques. J Infect Dis (1993) 1.01
Mechanisms associated with thymocyte apoptosis induced by simian immunodeficiency virus. J Immunol (2000) 1.01
Defining T-cell-mediated immune responses in rotavirus-infected juvenile rhesus macaques. J Virol (2004) 1.00
Dilated cardiomyopathy associated with simian AIDS in nonhuman primates. Circulation (2000) 0.99
Simian immunodeficiency virus-inoculated macaques acquire Mycobacterium avium from potable water during AIDS. J Infect Dis (1997) 0.98
Genetic and biochemical studies of phosphomannose isomerase deficient mutants of Saccharomyces cerevisiae. Mol Gen Genet (1976) 0.98
Induction of simian acquired immune deficiency syndrome (SAIDS) with a molecular clone of a type D SAIDS retrovirus. J Virol (1987) 0.98
Neuropathogenesis of simian immunodeficiency virus in neonatal rhesus macaques. Am J Pathol (1999) 0.97
Enteropathogenic Escherichia coli and ulcerative colitis in cotton-top tamarins (Saguinus oedipus). J Infect Dis (2001) 0.96
Association of simian virus 40 with a central nervous system lesion distinct from progressive multifocal leukoencephalopathy in macaques with AIDS. Am J Pathol (1999) 0.96
Induction of disseminated Mycobacterium avium in simian AIDS is dependent upon simian immunodeficiency virus strain and defective granuloma formation. Am J Pathol (2001) 0.95
Mycobacterium avium complex in macaques with AIDS is associated with a specific strain of simian immunodeficiency virus and prolonged survival after primary infection. J Infect Dis (1995) 0.95
Identification of enteropathogenic Escherichia coli in simian immunodeficiency virus-infected infant and adult rhesus macaques. J Clin Microbiol (2001) 0.93
Magnetic resonance spectroscopy: an in vivo tool for monitoring cerebral injury in SIV-infected macaques. J Med Primatol (2002) 0.92
VCAM-1 expression and leukocyte trafficking to the CNS occur early in infection with pathogenic isolates of SIV. J Med Primatol (1995) 0.91
Simian immunodeficiency virus infection of macaque bone marrow macrophages correlates with disease progression in vivo. Am J Pathol (1991) 0.90
Localization of simian immunodeficiency virus nucleic acid and antigen in brains of fetal macaques inoculated in utero. Am J Pathol (1996) 0.89
Chronic immune stimulation accelerates SIV-induced disease progression. J Med Primatol (2001) 0.88
Rhesus macaque brain microvessel endothelial cells behave in a manner phenotypically distinct from umbilical vein endothelial cells. J Neuroimmunol (2001) 0.88
S100β as a novel and accessible indicator for the presence of monocyte-driven encephalitis in AIDS. Neuropathol Appl Neurobiol (2012) 0.87
Quantitative evaluation of Enterocytozoon bieneusi infection in simian immunodeficiency virus-infected rhesus monkeys. J Med Primatol (2003) 0.87
Simian immunodeficiency virus disrupts extended lengths of the blood--brain barrier. J Med Primatol (2005) 0.86
Bacterial translocation across enterocytes: results of a study of bacterial-enterocyte interactions utilizing Caco-2 cells. Shock (1994) 0.86
Characterization of the cutaneous exanthem in macaques infected with a Nef gene variant of SIVmac239. J Invest Dermatol (1998) 0.84
Role of mucin, mannose, and beta-1 integrin receptors in Escherichia coli translocation across Caco-2 cell monolayers. Shock (1994) 0.84
Activation of the blood-brain barrier by SIV (simian immunodeficiency virus) requires cell-associated virus and is not restricted to endothelial cell activation. Biochem Soc Trans (2004) 0.83
Pulmonary cryptosporidiosis in simian immunodeficiency virus-infected rhesus macaques. Vet Pathol (2000) 0.83
Bacterial translocation is bacterial species dependent: results using the human Caco-2 intestinal cell line. J Trauma (1994) 0.83
Expression of serotonin transporters by peripheral blood mononuclear cells of rhesus monkeys (Macaca mulatta). Cell Immunol (2007) 0.83
Proliferative potential of canine oral epulides and malignant neoplasms assessed by bromodeoxyuridine labeling. Vet Pathol (1999) 0.81
A case of pulmonary cestodiasis in a simian immunodeficiency virus-infected pigtailed macaque (Macaca nemestrina) in which virus-infected leukocytes are present within the lesion. J Med Primatol (1996) 0.80
Immunoglobulin-A nephropathy with crescentic glomerulonephritis in a pigtailed macaque (Macaca nemestrina). Vet Pathol (2004) 0.80
The Caco-2 cell monolayer system as an in vitro model for studying bacterial-enterocyte interactions and bacterial translocation. J Burn Care Rehabil (1994) 0.80
Intrathecal synthesis of IgG in simian immunodeficiency virus (SIV)-infected rhesus macaques (Macaca mulatta). AIDS Res Hum Retroviruses (1994) 0.80
Assessment of the efficacy of nonablative long-pulsed 1064-nm Nd:YAG laser treatment of wrinkles compared at 2, 4, and 6 months. Facial Plast Surg (2005) 0.80
Effect of levamisole on major histocompatibility complex class I expression in colorectal and breast carcinoma cell lines. Cancer (1993) 0.80
Quantitative image analysis of simian immunodeficiency virus replication in macrophages coinfected with Mycobacterium avium complex. J Infect Dis (2000) 0.80
Evaluation of anti-human antibodies for immunohistochemistry on archival nonhuman primate tissues. J Med Primatol (1996) 0.80
Nodular Pneumocystis carinii pneumonia in SIV-infected macaques. Vet Pathol (1999) 0.79
Oral immunization studies with Streptococcus mutans and influenza vaccines in rhesus macaque monkeys. Adv Exp Med Biol (1995) 0.79
Effects of sex, age, puncture site, and blood contamination on the clinical chemistry of cerebrospinal fluid in rhesus macaques (Macaca mulatta). Am J Vet Res (1993) 0.78
Survival and failure to thrive in the SIV-infected juvenile rhesus monkey. J Acquir Immune Defic Syndr (1999) 0.78
Expression of peripherin in the brain of macaques (Macaca mulatta and Macaca fascicularis) occurs in astrocytes rather than neurones and is associated with encephalitis. Neuropathol Appl Neurobiol (2001) 0.77
Role of redox systems on Fe3+ uptake by transformed human intestinal epithelial (Caco-2) cells. Am J Physiol (1994) 0.77