Published in Science on October 26, 2001
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miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res (2006) 39.25
MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell (2007) 38.42
Human MicroRNA targets. PLoS Biol (2004) 34.51
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2002) 32.26
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
The microRNA Registry. Nucleic Acids Res (2004) 29.45
Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res (2005) 29.17
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A (2004) 28.29
Specificity of microRNA target selection in translational repression. Genes Dev (2004) 21.14
MicroRNA genes are transcribed by RNA polymerase II. EMBO J (2004) 20.65
A uniform system for microRNA annotation. RNA (2003) 20.28
MicroRNAs in plants. Genes Dev (2002) 20.12
Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol (2009) 19.99
MicroRNA maturation: stepwise processing and subcellular localization. EMBO J (2002) 19.47
miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev (2002) 19.24
Fast and effective prediction of microRNA/target duplexes. RNA (2004) 18.10
The microRNAs of Caenorhabditis elegans. Genes Dev (2003) 17.70
siRNAs can function as miRNAs. Genes Dev (2003) 16.08
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol (2004) 15.15
CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana. Curr Biol (2002) 15.13
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Small silencing RNAs: an expanding universe. Nat Rev Genet (2009) 13.88
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol (2003) 13.32
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Regulation of flowering time and floral organ identity by a MicroRNA and its APETALA2-like target genes. Plant Cell (2003) 11.69
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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev (2002) 10.71
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Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure. Proc Natl Acad Sci U S A (2004) 10.35
New microRNAs from mouse and human. RNA (2003) 10.35
Endogenous and silencing-associated small RNAs in plants. Plant Cell (2002) 10.07
A biochemical framework for RNA silencing in plants. Genes Dev (2003) 9.95
Computational identification of Drosophila microRNA genes. Genome Biol (2003) 9.86
A combined computational-experimental approach predicts human microRNA targets. Genes Dev (2004) 9.82
A microRNA array reveals extensive regulation of microRNAs during brain development. RNA (2003) 9.76
Intronic microRNA precursors that bypass Drosha processing. Nature (2007) 9.65
Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res (2007) 9.61
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev (2004) 9.32
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet (2007) 9.25
RNA sequencing: advances, challenges and opportunities. Nat Rev Genet (2010) 8.96
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci U S A (2003) 8.73
The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR. Genes Dev (2004) 8.42
microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci U S A (2006) 8.24
SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes Dev (2004) 8.18
Sequence-specific inhibition of small RNA function. PLoS Biol (2004) 7.98
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc Natl Acad Sci U S A (2003) 7.95
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA (2004) 7.71
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell (2007) 7.70
Sequence requirements for micro RNA processing and function in human cells. RNA (2003) 7.46
Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol (2004) 7.33
Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev (2010) 7.14
MicroRNA expression detected by oligonucleotide microarrays: system establishment and expression profiling in human tissues. Genome Res (2004) 6.98
MicroRNAs in stress signaling and human disease. Cell (2012) 6.93
The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development. Genes Dev (2004) 6.69
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A (2005) 6.61
Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer (2007) 6.57
Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev (2002) 6.43
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol (2007) 6.41
The functional role of long non-coding RNA in human carcinomas. Mol Cancer (2011) 6.37
Numerous microRNPs in neuronal cells containing novel microRNAs. RNA (2003) 6.28
Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods (2008) 6.22
Inference of miRNA targets using evolutionary conservation and pathway analysis. BMC Bioinformatics (2007) 6.21
Myogenic factors that regulate expression of muscle-specific microRNAs. Proc Natl Acad Sci U S A (2006) 6.19
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev (2002) 6.10
miRNAs in human cancer. J Pathol (2010) 6.02
The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell (2005) 5.90
Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci U S A (2005) 5.88
Genome-wide profiling and analysis of Arabidopsis siRNAs. PLoS Biol (2007) 5.86
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res (2011) 5.83
Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat Rev Genet (2008) 5.83
Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs. Genes Dev (2005) 5.78
A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res (2004) 5.77
The database of experimentally supported targets: a functional update of TarBase. Nucleic Acids Res (2008) 5.65
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer (2006) 5.47
Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res (2005) 5.44
miRNA profiling of naïve, effector and memory CD8 T cells. PLoS One (2007) 5.43
Chromatin structure analyses identify miRNA promoters. Genes Dev (2008) 5.40
microRNAs join the p53 network--another piece in the tumour-suppression puzzle. Nat Rev Cancer (2007) 5.38
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet (2007) 5.33
A pyrosequencing-tailored nucleotide barcode design unveils opportunities for large-scale sample multiplexing. Nucleic Acids Res (2007) 5.33
Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes Dev (2005) 5.29
Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Res (2010) 5.29
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. Genome Res (2006) 5.23
Endogenous RNA interference provides a somatic defense against Drosophila transposons. Curr Biol (2008) 5.22
A high-throughput method to monitor the expression of microRNA precursors. Nucleic Acids Res (2004) 5.21
A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). Genes Dev (2009) 5.04
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
The Arabidopsis double-stranded RNA-binding protein HYL1 plays a role in microRNA-mediated gene regulation. Proc Natl Acad Sci U S A (2004) 4.95
A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii. Genes Dev (2007) 4.95
Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol (2005) 4.93
Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Res (2007) 4.91
miRGen: a database for the study of animal microRNA genomic organization and function. Nucleic Acids Res (2006) 4.91
Probing microRNAs with microarrays: tissue specificity and functional inference. RNA (2004) 4.91
The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution. Nat Struct Mol Biol (2008) 4.88
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A (2004) 4.85
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