Published in Invest Ophthalmol Vis Sci on November 01, 2001
TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways. J Immunol (2010) 1.70
Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease. Br J Ophthalmol (2006) 1.53
Pseudomonas aeruginosa lipopolysaccharide: a major virulence factor, initiator of inflammation and target for effective immunity. Int J Med Microbiol (2007) 1.49
Toll-like receptors and corneal innate immunity. Curr Mol Med (2006) 1.44
Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88. Infect Immun (2006) 1.43
A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells. PLoS Pathog (2007) 1.41
Defensin expression by the cornea: multiple signalling pathways mediate IL-1beta stimulation of hBD-2 expression by human corneal epithelial cells. Invest Ophthalmol Vis Sci (2003) 1.39
Toll-like receptors at the ocular surface. Ocul Surf (2008) 1.18
Toll-like receptor 4 (TLR4) of retinal pigment epithelial cells participates in transmembrane signaling in response to photoreceptor outer segments. J Gen Physiol (2004) 1.14
Inhibition of corneal inflammation by the TLR4 antagonist Eritoran tetrasodium (E5564). Invest Ophthalmol Vis Sci (2008) 1.12
Role of EGFR transactivation in preventing apoptosis in Pseudomonas aeruginosa-infected human corneal epithelial cells. Invest Ophthalmol Vis Sci (2004) 1.12
C-Jun NH2 terminal kinase (JNK) is an essential mediator of Toll-like receptor 2-induced corneal inflammation. J Leukoc Biol (2008) 1.11
Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection. Curr Eye Res (2005) 1.09
Toll-like receptors in ocular surface disease. Exp Eye Res (2010) 1.05
Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of Fusarium solani in immortalized human corneal epithelial cells. Mol Vis (2007) 1.05
Toll-like receptors and the eye. Invest Ophthalmol Vis Sci (2006) 1.04
TLRs and NODs mRNA expression pattern in healthy mouse eye. Br J Ophthalmol (2005) 1.03
Increased Toll-like receptor 4 expression in infants with respiratory syncytial virus bronchiolitis. Clin Exp Immunol (2004) 1.02
Expression of toll-like receptors in human limbal and conjunctival epithelial cells. Mol Vis (2007) 0.96
Expression of toll-like receptor 4 contributes to corneal inflammation in experimental dry eye disease. Invest Ophthalmol Vis Sci (2012) 0.94
Lack of MD-2 expression in human corneal epithelial cells is an underlying mechanism of lipopolysaccharide (LPS) unresponsiveness. Immunol Cell Biol (2008) 0.93
Lipopolysaccharide induced synthesis of CD14 proteins and its gene expression in hepatocytes during endotoxemia. World J Gastroenterol (2002) 0.92
Glutathione peroxidase-1 modulates lipopolysaccharide-induced adhesion molecule expression in endothelial cells by altering CD14 expression. FASEB J (2010) 0.87
Expression of CRAMP via PGN-TLR-2 and of alpha-defensin-3 via CpG-ODN-TLR-9 in corneal fibroblasts. Br J Ophthalmol (2006) 0.86
Acanthamoeba-cytopathic protein induces apoptosis and proinflammatory cytokines in human corneal epithelial cells by cPLA2α activation. Invest Ophthalmol Vis Sci (2012) 0.85
Glucocorticoids inhibit the innate immune system of human corneal fibroblast through their suppression of toll-like receptors. Mol Vis (2009) 0.85
Pathogenic strains of Acanthamoeba are recognized by TLR4 and initiated inflammatory responses in the cornea. PLoS One (2014) 0.84
Hypoxia-altered signaling pathways of toll-like receptor 4 (TLR4) in human corneal epithelial cells. Mol Vis (2009) 0.84
HMGB1 is an early and critical mediator in an animal model of uveitis induced by IRBP-specific T cells. J Leukoc Biol (2013) 0.83
Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16. Mucosal Immunol (2015) 0.81
A European perspective on topical ophthalmic antibiotics: current and evolving options. Ophthalmol Eye Dis (2011) 0.80
TLR4 mediates human retinal pigment epithelial endotoxin binding and cytokine expression. Trans Am Ophthalmol Soc (2005) 0.80
The delayed response of Toll-like receptors may relate to Pseudomonas aeruginosa keratitis exacerbating rapidly at the early stages of infection. Eur J Clin Microbiol Infect Dis (2009) 0.80
Cortisol biosynthesis in the human ocular surface innate immune response. PLoS One (2014) 0.79
Ketamine suppresses intestinal TLR4 expression and NF-kappaB activity in lipopolysaccharide-treated rats. Croat Med J (2006) 0.79
Significance of arachidonic acid in ocular infections and inflammation. Inflamm Cell Signal (2015) 0.76
Effect of the Toll-like receptor 4 antagonist eritoran on retinochoroidal inflammatory damage in a rat model of endotoxin-induced inflammation. Mediators Inflamm (2014) 0.76
Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model. Invest Ophthalmol Vis Sci (2016) 0.76
Exogenous MD-2 confers lipopolysaccharide responsiveness to human corneal epithelial cells with intracellular expression of TLR4 and CD14. Inflammation (2011) 0.76
High glucose may decrease the innate immune through TLRs in cornea epithelium. Mol Vis (2011) 0.75
Regulation of Toll-like receptor expression in human conjunctival epithelial cells. Mediators Inflamm (2014) 0.75
Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4. Mol Vis (2017) 0.75
The anti-inflammatory effects of asiatic acid in lipopolysaccharide-stimulated human corneal epithelial cells. Int J Ophthalmol (2017) 0.75
Role of toll-like receptors in human iris pigment epithelial cells and their response to pathogen-associated molecular patterns. J Inflamm (Lond) (2014) 0.75
Corneal Fibroblasts as Sentinel Cells and Local Immune Modulators in Infectious Keratitis. Int J Mol Sci (2017) 0.75
Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med (1995) 5.98
Normal polysomnographic values for children and adolescents. Am Rev Respir Dis (1992) 5.18
Smoking duration, intensity, and risk of Parkinson disease. Neurology (2010) 3.19
The corneal endothelium. Normal and pathologic structure and function. Ophthalmology (1982) 2.94
Treatment of chronic non-A,non-B hepatitis with recombinant human alpha interferon. A preliminary report. N Engl J Med (1986) 2.85
Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp Med (1990) 2.62
Factors associated with the transition to nonprone sleep positions of infants in the United States: the National Infant Sleep Position Study. JAMA (1998) 2.56
Long-term therapy of chronic hepatitis B with lamivudine. Hepatology (2000) 2.49
Ribavirin as therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (1995) 2.49
Role of fimbriae in Porphyromonas gingivalis invasion of gingival epithelial cells. Infect Immun (1997) 2.27
Ordered assembly of roX RNAs into MSL complexes on the dosage-compensated X chromosome in Drosophila. Curr Biol (2000) 1.98
Human sclera: thickness and surface area. Am J Ophthalmol (1998) 1.96
Corneal endothelial changes in type I and type II diabetes mellitus. Am J Ophthalmol (1984) 1.94
Signaling system in Porphyromonas gingivalis based on a LuxS protein. J Bacteriol (2001) 1.87
The biologically active isomers of conjugated linoleic acid. Prog Lipid Res (2001) 1.82
Classification of corneal endothelial disorders based on neural crest origin. Ophthalmology (1984) 1.81
Low-intensity hematopoietic stem-cell transplantation across human leucocyte antigen barriers in dyskeratosis congenita. Bone Marrow Transplant (2003) 1.80
Randomized, controlled trial of recombinant human alpha-interferon in patients with chronic hepatitis B. Gastroenterology (1988) 1.74
Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups. Hum Mol Genet (1997) 1.65
Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds. Nature (1993) 1.63
Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses. J Food Sci (2008) 1.63
Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma. Am J Pathol (1995) 1.59
IFN-beta 2, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell lines. J Immunol (1989) 1.54
Obstructive sleep apnea in children with Down syndrome. Pediatrics (1991) 1.53
Fluorescence image analysis of the association between Porphyromonas gingivalis and gingival epithelial cells. Cell Microbiol (1999) 1.52
Visual attention deficits contribute to impaired facial emotion recognition in boys with attention-deficit/hyperactivity disorder. Neuropediatrics (2009) 1.51
Obstacles to discharge of ventilator-assisted children from the hospital to home. Chest (1993) 1.50
Anesthesia for intraocular surgery. Surv Ophthalmol (2001) 1.49
Inhibition of epithelial cell apoptosis by Porphyromonas gingivalis. FEMS Microbiol Lett (2001) 1.47
Changes in the normal corneal endothelial cellular pattern as a function of age. Curr Eye Res (1985) 1.46
Proteinase-activated receptor-2 in human skin: tissue distribution and activation of keratinocytes by mast cell tryptase. Exp Dermatol (1999) 1.45
10-Year follow-up after interferon-alpha therapy for chronic hepatitis C. Hepatology (1998) 1.44
Expression pattern of germ cell-specific genes in the testis of patients with nonobstructive azoospermia: usefulness as a molecular marker to predict the presence of testicular sperm. Fertil Steril (2000) 1.44
Lamivudine for chronic delta hepatitis. Hepatology (1999) 1.44
Intraocular irrigating solutions. Their effect on the corneal endothelium. Arch Ophthalmol (1975) 1.43
Inhibitory and anti-inflammatory effects of the Helicobacter pylori-derived antimicrobial peptide HPA3NT3 against Propionibacterium acnes in the skin. Br J Dermatol (2014) 1.43
Drug delivery for posterior segment eye disease. Invest Ophthalmol Vis Sci (2000) 1.43
Physical activities and future risk of Parkinson disease. Neurology (2010) 1.42
Unexpected corneal endothelial cell decompensation after intraocular surgery with instruments sterilized by plasma gas. Ophthalmology (2000) 1.41
Human scleral permeability. Effects of age, cryotherapy, transscleral diode laser, and surgical thinning. Invest Ophthalmol Vis Sci (1995) 1.39
Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.38
Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV. Gene Ther (2009) 1.34
Use of nasal continuous positive airway pressure as treatment of childhood obstructive sleep apnea. J Pediatr (1995) 1.34
Psychiatric complications of long-term interferon alfa therapy. Arch Intern Med (1987) 1.33
Transscleral drug delivery for posterior segment disease. Adv Drug Deliv Rev (2001) 1.32
A pilot study of ribavirin therapy for chronic hepatitis C. Hepatology (1992) 1.30
Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes. J Clin Invest (1994) 1.29
Comparison of the corneal endothelium in an American and a Japanese population. Arch Ophthalmol (1985) 1.28
Long-term follow-up of patients with chronic hepatitis B treated with interferon alfa. Gastroenterology (1997) 1.28
Heart rate variability in children with obstructive sleep apnea. Sleep (1997) 1.27
Synergistic activation of the inhibin alpha-promoter by steroidogenic factor-1 and cyclic adenosine 3',5'-monophosphate. Mol Endocrinol (2000) 1.25
Response of the corneal endothelium to cataract surgery. Arch Ophthalmol (1986) 1.24
Effects of intraocular irrigating solutions on the corneal endothelium after in vivo anterior chamber irrigation. Am J Ophthalmol (1985) 1.24
Ultrastructure in anterior and posterior stroma of perfused human and rabbit corneas. Relation to transparency. Invest Ophthalmol Vis Sci (1995) 1.23
Coinvasion of dentinal tubules by Porphyromonas gingivalis and Streptococcus gordonii depends upon binding specificity of streptococcal antigen I/II adhesin. Infect Immun (2000) 1.20
Follicle-stimulating hormone stimulates protein kinase A-mediated histone H3 phosphorylation and acetylation leading to select gene activation in ovarian granulosa cells. J Biol Chem (2001) 1.19
Abnormal ventilatory patterns during sleep in infants with myelomeningocele. J Pediatr (1986) 1.19
Regulation of epidermal cell interleukin-6 production by UV light and corticosteroids. J Invest Dermatol (1991) 1.17
Mechanisms of action of conjugated linoleic acid: evidence and speculation. Proc Soc Exp Biol Med (2000) 1.16
Isolation and initial characterization of tumoricidal monokine(s) from the human monocytic leukemia cell line THP-1. J Natl Cancer Inst (1985) 1.16
Biliary cystadenoma of the liver. J Hepatobiliary Pancreat Surg (1998) 1.15
Sustained expression of Mect1-Maml2 is essential for tumor cell growth in salivary gland cancers carrying the t(11;19) translocation. Oncogene (2006) 1.15
Ultraviolet irradiation induces the production of multiple cytokines by human corneal cells. Invest Ophthalmol Vis Sci (1997) 1.15
Ocular surgical pharmacology: corneal endothelial safety and toxicity. Curr Opin Ophthalmol (2003) 1.15
The natural history of acute hepatitis C: clinical presentation, laboratory findings and treatment outcomes. Aliment Pharmacol Ther (2010) 1.14
Intraocular irrigating solutions. A comparative study of BSS Plus and lactated Ringer's solution. Arch Ophthalmol (1978) 1.14
Conservation of ecdysis-triggering hormone signalling in insects. J Exp Biol (2003) 1.14
Mechanisms that mediate negative regulation of the thyroid-stimulating hormone alpha gene by the thyroid hormone receptor. J Biol Chem (1999) 1.13
Novel production of interleukin-1 receptor antagonist peptides in normal human cornea. J Clin Invest (1995) 1.13
The corneal toxicity of presurgical skin antiseptics. Am J Ophthalmol (1984) 1.11
In vivo effects of air and sulfur hexafluoride gas on rabbit corneal endothelium. Invest Ophthalmol (1972) 1.11
The pH tolerance of rabbit and human corneal endothelium. Invest Ophthalmol Vis Sci (1979) 1.10
Levels of interleukin-2, interferon-gamma, and interleukin-4 in bronchoalveolar lavage fluid from patients with Mycoplasma pneumonia: implication of tendency toward increased immunoglobulin E production. Pediatrics (2001) 1.10
A new glycosaminoglycan from the giant African snail Achatina fulica. J Biol Chem (1996) 1.10
Functional and structural changes in the corneal edothelium during in vitro perfusion. Invest Ophthalmol (1973) 1.09
An analysis of utilization and access from the NHIS: 1984-92. Health Care Financ Rev (1995) 1.09
Effect of thiol-oxidation of glutathione with diamide on corneal endothelial function, junctional complexes, and microfilaments. J Cell Biol (1976) 1.09
Comparative toxicity of intraocular irrigating solutions on the corneal endothelium. Am J Ophthalmol (1976) 1.08
The trans-10,cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes. J Nutr (2000) 1.08
Neuropeptides in the skin: interactions between the neuroendocrine and the skin immune systems. Exp Dermatol (1998) 1.08
Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer. Oncogene (2009) 1.08
A controlled trial of naloxone infusions for the pruritus of chronic cholestasis. Gastroenterology (1992) 1.08
Comparison of conjunctival and corneal surface areas in rabbit and human. Curr Eye Res (1988) 1.07
Searching the Porphyromonas gingivalis genome with peptide fragmentation mass spectra. Analyst (2001) 1.07
Effect of the ophthalmic preservative thimerosal on rabbit and human corneal endothelium. Invest Ophthalmol Vis Sci (1977) 1.06
Correlation of histologic corneal endothelial cell counts with specular microscopic cell density. Arch Ophthalmol (1992) 1.06
Corneal endothelial morphology in the rat. Effects of aging, diabetes, and topical aldose reductase inhibitor treatment. Invest Ophthalmol Vis Sci (1988) 1.06
Hypercapneic arousal responses in children with congenital central hypoventilation syndrome. Pediatrics (1991) 1.05
Neuropeptide regulation of human dermal microvascular endothelial cell ICAM-1 expression and function. Am J Physiol (1998) 1.05
Pump function of the human corneal endothelium. Effects of age and cornea guttata. Ophthalmology (1985) 1.05
Alcohol intake and risk of thyroid cancer in the NIH-AARP Diet and Health Study. Br J Cancer (2009) 1.04