Published in J Biol Chem on November 19, 2001
Practical uses for ecdysteroids in mammals including humans: an update. J Insect Sci (2003) 1.18
Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia. Cancer Res (2007) 1.11
Reciprocal regulation of glutathione S-transferase spliceforms and the Drosophila c-Jun N-terminal kinase pathway components. Biochem J (2004) 0.90
Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry. J Virol (2013) 0.85
Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors. Chem Cent J (2011) 0.83
Multiple control of interleukin-8 gene expression. J Leukoc Biol (2002) 5.35
Interleukin-1 (IL-1) pathway. Sci Signal (2010) 2.58
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J Biol Chem (2004) 2.29
Targeting innate immunity protein kinase signalling in inflammation. Nat Rev Drug Discov (2009) 2.01
Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice. Cancer Res (2005) 1.83
IL-1 family nomenclature. Nat Immunol (2010) 1.79
NF-kappaB: a multifaceted transcription factor regulated at several levels. Chembiochem (2004) 1.76
NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP. J Cell Biol (2004) 1.71
The identification of microRNAs in a genomically unstable region of human chromosome 8q24. Mol Cancer Res (2008) 1.71
Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import. J Immunol (2004) 1.69
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med (2009) 1.69
Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets. Mol Cell Biol (2007) 1.56
Phosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination. EMBO Rep (2009) 1.54
Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR. Mol Cell Biol (2004) 1.52
Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom (2005) 1.44
Inhibitor of apoptosis proteins as novel targets in inflammatory processes. Arterioscler Thromb Vasc Biol (2011) 1.43
Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes. J Biol Chem (2003) 1.35
MEK1-dependent delayed expression of Fos-related antigen-1 counteracts c-Fos and p65 NF-kappaB-mediated interleukin-8 transcription in response to cytokines or growth factors. J Biol Chem (2004) 1.29
Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization. Biochem Biophys Res Commun (2003) 1.29
Histological staining methods preparatory to laser capture microdissection significantly affect the integrity of the cellular RNA. BMC Genomics (2006) 1.29
Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon. J Biol Chem (2006) 1.28
Interleukin-1beta (IL-1beta) processing pathway. Sci Signal (2010) 1.26
Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor. J Biol Chem (2004) 1.21
c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol Cell Biol (2008) 1.20
Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus. J Virol (2006) 1.13
Evidence for general stabilization of mRNAs in response to UV light. Eur J Biochem (2002) 1.11
The Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathway. EMBO Rep (2006) 1.10
Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway. J Biol Chem (2008) 1.08
Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.08
Inhibition of mRNA deadenylation and degradation by different types of cell stress. Biol Chem (2006) 1.07
CX3CR1+ c-kit+ bone marrow cells give rise to CD103+ and CD103- dendritic cells with distinct functional properties. J Immunol (2008) 1.07
c-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies. J Cell Biol (2011) 1.04
Differential gene regulation by Epstein-Barr virus type 1 and type 2 EBNA2. J Virol (2008) 1.03
Silencing or permanent activation: host-cell responses in models of persistent Chlamydia pneumoniae infection. Cell Microbiol (2005) 1.03
IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IκBζ mRNA. J Biol Chem (2010) 1.00
Cell target genes of Epstein-Barr virus transcription factor EBNA-2: induction of the p55alpha regulatory subunit of PI3-kinase and its role in survival of EREB2.5 cells. J Gen Virol (2006) 1.00
Proteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1. Eur J Immunol (2002) 1.00
Cellular gene expression that correlates with EBER expression in Epstein-Barr Virus-infected lymphoblastoid cell lines. J Virol (2011) 0.98
The death domain of IRAK-1: an oligomerization domain mediating interactions with MyD88, Tollip, IRAK-1, and IRAK-4. Biochem Biophys Res Commun (2007) 0.98
Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism. J Biol Chem (2011) 0.96
Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification. J Immunol (2005) 0.95
Host chemokine (C-C motif) ligand-2 (CCL2) is differentially regulated in HIV type 1 (HIV-1)-infected individuals. Int Immunol (2006) 0.95
Activation of NF-kappaB and IL-8 by Yersinia enterocolitica invasin protein is conferred by engagement of Rac1 and MAP kinase cascades. Cell Microbiol (2003) 0.95
Inhibition of mRNA deadenylation and degradation by ultraviolet light. Biol Chem (2005) 0.94
ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death. J Neurochem (2003) 0.93
Nonhematopoietic cells control the outcome of infection with Listeria monocytogenes in a nucleotide oligomerization domain 1-dependent manner. Infect Immun (2009) 0.93
Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression. PLoS One (2012) 0.93
Induction of apoptosis by protein kinase C delta is independent of its kinase activity. J Biol Chem (2002) 0.93
CD4+ T cells recognizing specific antigen deposited in glomeruli cause glomerulonephritis-like kidney injury. Clin Immunol (2002) 0.93
The diesel exhaust component pyrene induces expression of IL-8 but not of eotaxin. Int Immunopharmacol (2003) 0.92
Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease. Inflamm Bowel Dis (2009) 0.92
Role of the Kaposi's sarcoma-associated herpesvirus K15 SH3 binding site in inflammatory signaling and B-cell activation. J Virol (2010) 0.91
Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression. PLoS Pathog (2012) 0.91
Death receptor-induced signaling pathways are differentially regulated by gamma interferon upstream of caspase 8 processing. Mol Cell Biol (2005) 0.91
The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB. Nucleic Acids Res (2012) 0.90
Yersinia enterocolitica YopP inhibits MAP kinase-mediated antigen uptake in dendritic cells. Cell Microbiol (2006) 0.90
Peptides as signaling inhibitors for mammalian MAP kinase cascades. Curr Pharm Des (2009) 0.90
Comparative analysis of T-cell costimulation and CD43 activation reveals novel signaling pathways and target genes. Blood (2004) 0.89
Functional characterization of the M-type K15-encoded membrane protein of Kaposi's sarcoma-associated herpesvirus. J Gen Virol (2007) 0.88
Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive. J Cell Sci (2004) 0.88
Peptide-mediated disruption of NFkappaB/NRF interaction inhibits IL-8 gene activation by IL-1 or Helicobacter pylori. J Immunol (2007) 0.88
Simultaneous quantification of sirolimus, everolimus, tacrolimus and cyclosporine by liquid chromatography-mass spectrometry (LC-MS). Clin Chem Lab Med (2002) 0.88
Toll-like receptor 4 signalling is specifically TGF-beta-activated kinase 1 independent in synovial fibroblasts. Rheumatology (Oxford) (2011) 0.87
The V5 domain of protein kinase C plays a critical role in determining the isoform-specific localization, translocation, and biological function of protein kinase C-delta and -epsilon. Mol Cancer Res (2004) 0.87
A preservation method that allows recovery of intact RNA from tissues dissected by laser capture microdissection. Anal Biochem (2002) 0.87
Phosphorylation of paxillin at threonine 538 by PKCdelta regulates LFA1-mediated adhesion of lymphoid cells. J Cell Sci (2010) 0.86
Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways. FEBS J (2009) 0.86
Identification of mouse genes with highly specific expression patterns in differentiated intestinal epithelium. Gastroenterology (2006) 0.86
Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c-Myc in a model of plasma cell neoplasia. BMC Genomics (2007) 0.86
c-Myc-induced genomic instability. J Environ Pathol Toxicol Oncol (2003) 0.86
Signal integration, crosstalk mechanisms and networks in the function of inflammatory cytokines. Biochim Biophys Acta (2011) 0.85
Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities. Pharm Res (2008) 0.85
Down-regulation of interleukin-16 in human mast cells HMC-1 by Clostridium difficile toxins A and B. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.84
MKK7 mediates miR-493-dependent suppression of liver metastasis of colon cancer cells. Cancer Sci (2014) 0.84
Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia. Blood (2011) 0.84
The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells. PLoS Pathog (2013) 0.84
Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats. Dig Dis Sci (2004) 0.83
Quantification of the carbapenem antibiotic ertapenem in human plasma by a validated liquid chromatography-mass spectrometry method. Clin Chim Acta (2005) 0.83
Regulation of TAK1/TAB1-mediated IL-1β signaling by cytoplasmic PPARβ/δ. PLoS One (2013) 0.82
NF-kappaB-repressing factor inhibits elongation of human immunodeficiency virus type 1 transcription by DRB sensitivity-inducing factor. Mol Cell Biol (2005) 0.81
JKTBP1 is involved in stabilization and IRES-dependent translation of NRF mRNAs by binding to 5' and 3' untranslated regions. J Mol Biol (2011) 0.81
Induction of C3 and CCL2 by C3a in keratinocytes: a novel autocrine amplification loop of inflammatory skin reactions. J Immunol (2006) 0.81
Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcription. J Clin Immunol (2010) 0.81
Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K15 gene of Kaposi's sarcoma-associated herpesvirus. J Gen Virol (2009) 0.81
Threonine 66 in the death domain of IRAK-1 is critical for interaction with signaling molecules but is not a target site for autophosphorylation. J Leukoc Biol (2008) 0.81
Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma. J Neurochem (2008) 0.80