Retracted: This article has been retracted.

The IL-15R alpha chain signals through association with Syk in human B cells.

PubWeight™: 1.20‹?› | Rank: Top 10%

🔗 View Article (PMID 11714793)

Published in J Immunol on December 01, 2001


E Bulanova1, V Budagian, T Pohl, H Krause, H Dürkop, R Paus, S Bulfone-Paus

Author Affiliations

1: Department of Immunology and Cell Biology, Research Center Borstel, Borstel, Germany.

Articles citing this

Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis. J Exp Med (2004) 2.78

Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo. J Immunol (2006) 2.69

Retracted A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control. EMBO J (2005) 1.72

Trans-presentation: a novel mechanism regulating IL-15 delivery and responses. Immunol Lett (2009) 1.64

Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. Hum Gene Ther (2009) 1.57

NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha. J Clin Invest (2007) 1.37

Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model. J Clin Invest (2003) 1.37

Integration of cytokine and heterologous receptor signaling pathways. Nat Immunol (2009) 1.36

Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates. Proc Natl Acad Sci U S A (2012) 1.30

IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells. Proc Natl Acad Sci U S A (2004) 1.25

How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha. Mol Cell Biol (2008) 1.11

Retracted Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. Mol Cell Biol (2005) 1.10

Co-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruzi. PLoS Negl Trop Dis (2011) 0.99

Detection of a functional hybrid receptor gammac/GM-CSFRbeta in human hematopoietic CD34+ cells. J Exp Med (2003) 0.92

Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells. Proc Natl Acad Sci U S A (2003) 0.91

The IL-15 receptor {alpha} chain cytoplasmic domain is critical for normal IL-15Ralpha function but is not required for trans-presentation. Blood (2008) 0.85

Interleukin-15 enhances proliferation and chemokine secretion of human follicular dendritic cells. Immunology (2010) 0.84

The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2. Biochim Biophys Acta (2011) 0.81

Effect of interleukin-15 on the course of myocarditis in Coxsackievirus B3-infected BALB/c mice. Can J Cardiol (2009) 0.81

Subcellular expression pattern and role of IL-15 in pneumococci induced lung epithelial apoptosis. Histochem Cell Biol (2008) 0.79

Articles by these authors

A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. J Invest Dermatol (2001) 6.12

Sonic hedgehog signaling is essential for hair development. Curr Biol (1998) 5.58

Controls of hair follicle cycling. Physiol Rev (2001) 5.49

Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03

CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features. Blood (2000) 3.99

Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors. Pflugers Arch (1972) 3.46

Vaginal repair with mesh versus colporrhaphy for prolapse: a randomised controlled trial. BJOG (2009) 3.04

Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol (1999) 2.99

Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress. Physiol Rev (2000) 2.98

Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021. Proc Natl Acad Sci U S A (2001) 2.83

CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy. Blood (1995) 2.67

Conservation of microstructure between a sequenced region of the genome of rice and multiple segments of the genome of Arabidopsis thaliana. Genome Res (2001) 2.56

Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts. Oncogene (1999) 2.27

Huntington disease-linked locus D4S111 exposed as the alpha-L-iduronidase gene. Somat Cell Mol Genet (1991) 2.23

Interleukin-15 protects from lethal apoptosis in vivo. Nat Med (1997) 2.22

Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature (2000) 2.16

Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes. Immunol Today (1993) 2.09

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling. FASEB J (2000) 2.09

Promotion of collateral growth by granulocyte-macrophage colony-stimulating factor in patients with coronary artery disease: a randomized, double-blind, placebo-controlled study. Circulation (2001) 2.02

Molecular approaches to mammalian genetics. Cold Spring Harb Symp Quant Biol (1986) 1.99

Noggin is required for induction of the hair follicle growth phase in postnatal skin. FASEB J (2001) 1.95

A novel nuclear pore protein Nup82p which specifically binds to a fraction of Nsp1p. J Cell Biol (1995) 1.90

Melanogenesis is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth. J Invest Dermatol (1993) 1.88

Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain. Neuron (1992) 1.85

Analysis of apoptosis during hair follicle regression (catagen) Am J Pathol (1997) 1.82

BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed at a formol-resistant epitope. Blood (1989) 1.76

Graying: gerontobiology of the hair follicle pigmentary unit. Exp Gerontol (2001) 1.75

Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15. Blood (1999) 1.71

New selective inhibitors of the transmembrane Ca conductivity in mammalian myocardial fibres. Studies with the voltage clamp technique. Experientia (1972) 1.68

What are melanocytes really doing all day long...? Exp Dermatol (2009) 1.65

Retracted Death deflected: IL-15 inhibits TNF-alpha-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Ralpha chain. FASEB J (1999) 1.60

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF. EMBO J (1999) 1.59

Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin. J Lab Clin Med (1993) 1.58

Melanocytes as "sensory" and regulatory cells in the epidermis. J Theor Biol (1993) 1.55

Rel/NF-kappaB transcription factors: key mediators of B-cell activation. Immunol Rev (2000) 1.51

Kinetics of inactivation and recovery of the slow inward current in the mammalian ventricular myocardium. Pflugers Arch (1975) 1.50

Control of murine hair follicle regression (catagen) by TGF-beta1 in vivo. FASEB J (2000) 1.48

The complete DNA sequence of the Ectocarpus siliculosus Virus EsV-1 genome. Virology (2001) 1.46

The human hair follicle immune system: cellular composition and immune privilege. Br J Dermatol (2000) 1.42

Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids. Cancer Res (2000) 1.40

Failure of topical estrogen receptor agonists and antagonists to alter murine hair follicle cycling. J Invest Dermatol (1998) 1.40

Impaired NK1.1+ T cells do not prevent the development of an IgE-dependent allergic phenotype. Clin Exp Allergy (1998) 1.39

The 'melanocyte-keratin' mystery revisited: neither normal human epidermal nor hair follicle melanocytes express keratin 16 or keratin 6 in situ. Br J Dermatol (2009) 1.39

Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else? Exp Dermatol (2008) 1.39

The TGF-beta2 isoform is both a required and sufficient inducer of murine hair follicle morphogenesis. Dev Biol (1999) 1.38

The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation. Am J Pathol (1999) 1.38

Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived Neurotrophic functions. Am J Pathol (1999) 1.37

Role of nerve growth factor in a mouse model of allergic airway inflammation and asthma. Eur J Immunol (1998) 1.37

Alkaline phosphatase activity and localization during the murine hair cycle. Br J Dermatol (1994) 1.34

Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans. Exp Dermatol (1998) 1.33

The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen. Eur J Immunol (1994) 1.32

Selective inhibition of the transmembrane Ca conductivity of mammalian myocardial fibres by Ni, Co and Mn ions. Pflugers Arch (1973) 1.30

Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis? J Immunol (2000) 1.29

Inhibition of melanogenesis as an adjuvant strategy in the treatment of melanotic melanomas: selective review and hypothesis. Anticancer Res (1999) 1.29

Active hair growth (anagen) is associated with angiogenesis. J Invest Dermatol (2000) 1.29

Melanogenesis during the anagen-catagen-telogen transformation of the murine hair cycle. J Invest Dermatol (1994) 1.27

Involvement of hepatocyte growth factor/scatter factor and met receptor signaling in hair follicle morphogenesis and cycling. FASEB J (2000) 1.26

Feedback interaction of mechanical and electrical events in the isolated mammalian ventricular myocardium (cat papillary muscle). Pflugers Arch (1971) 1.26

Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J (2009) 1.25

Ca-movement controlling myocardial contractility. I. Voltage-, current- and time-dependence of mechanical activity under voltage clamp conditions (cat papillary muscles and trabeculae). Pflugers Arch (1973) 1.25

Management of alopecia areata. BMJ (2010) 1.25

PTEN/MMAC1 mutations in prostate cancer. Prostate Cancer Prostatic Dis (2000) 1.24

Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms. J Immunol (1997) 1.24

An improved MTT assay using the electron-coupling agent menadione. J Immunol Methods (1994) 1.24

Differential expression and activity of melanogenesis-related proteins during induced hair growth in mice. J Invest Dermatol (1991) 1.24

TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60. J Immunol (1998) 1.23

Concentration of proteins and removal of solutes. Methods Enzymol (1990) 1.22

E- and P-cadherin expression during murine hair follicle morphogenesis and cycling. Exp Dermatol (1999) 1.22

Frequent expression of interleukin-10 by Epstein-Barr virus-harboring tumor cells of Hodgkin's disease. Blood (1996) 1.21

Characterization of functional vanilloid receptors expressed by mast cells. Blood (1998) 1.21

Hair cycle-dependent plasticity of skin and hair follicle innervation in normal murine skin. J Comp Neurol (1997) 1.20

SV40-induced somatic mutations: possible relevance to viral transformation. Cold Spring Harb Symp Quant Biol (1980) 1.20

Genomic organization of the human PEX gene mutated in X-linked dominant hypophosphatemic rickets. Genome Res (1997) 1.19

Cutaneous expression of CRH and CRH-R. Is there a "skin stress response system?". Ann N Y Acad Sci (1999) 1.18

The Bacillus subtilis pnbA gene encoding p-nitrobenzyl esterase: cloning, sequence and high-level expression in Escherichia coli. Gene (1994) 1.18

Hair follicle expression of 1,25-dihydroxyvitamin D3 receptors during the murine hair cycle. Br J Dermatol (1994) 1.18

Endothelial K(+) channel lacks the Ca(2+) sensitivity-regulating beta subunit. FASEB J (2000) 1.17

Hair growth modulation by topical immunophilin ligands: induction of anagen, inhibition of massive catagen development, and relative protection from chemotherapy-induced alopecia. Am J Pathol (1997) 1.17

Indications for a 'brain-hair follicle axis (BHA)': inhibition of keratinocyte proliferation and up-regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P. FASEB J (2001) 1.17

Response of refractory Hodgkin's disease to monoclonal anti-CD30 immunotoxin. Lancet (1992) 1.16

Calcium-movement controlling cardiac contractility II. Analog computation of cardiac excitation-contraction coupling on the basis of calcium kinetics in a multi-compartment model. J Mol Cell Cardiol (1974) 1.15

What causes alopecia areata? Exp Dermatol (2013) 1.14

Expression parameters of the polycomb group proteins BMI1, SUZ12, RING1 and CBX7 in urothelial carcinoma of the bladder and their prognostic relevance. Tumour Biol (2008) 1.12

Rapid upregulation of mu opioid receptor mRNA in dorsal root ganglia in response to peripheral inflammation depends on neuronal conduction. Neuroscience (2004) 1.10

Ki-1 (CD30) antigen is released by Ki-1-positive tumor cells in vitro and in vivo. I. Partial characterization of soluble Ki-1 antigen and detection of the antigen in cell culture supernatants and in serum by an enzyme-linked immunosorbent assay. Eur J Immunol (1989) 1.09

Soluble interleukin-6 (IL-6) receptor augments central effects of IL-6 in vivo. FASEB J (1995) 1.06

Towards defining the pathogenesis of the hairless phenotype. J Invest Dermatol (1998) 1.06

Microsatellite analysis of plasma DNA from patients with clear cell renal carcinoma. Cancer Res (1998) 1.06

Evidence for complexed plastocyanin as the immediate electron donor of P-700. Biochim Biophys Acta (1980) 1.05

DNA-based detection of prostate cancer in blood, urine, and ejaculates. Ann N Y Acad Sci (2001) 1.05

Proopiomelanocortin expression in the skin during induced hair growth in mice. Experientia (1992) 1.05