PubRank

Seetharama A Acharya

Author PubWeight™ 27.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Dissociation of local nitric oxide concentration and vasoconstriction in the presence of cell-free hemoglobin oxygen carriers. Blood 2006 1.32
2 Early difference in tissue pH and microvascular hemodynamics in hemorrhagic shock resuscitation using polyethylene glycol-albumin- and hydroxyethyl starch-based plasma expanders. Shock 2005 1.05
3 Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. Protein J 2005 1.01
4 Survival time in severe hemorrhagic shock after perioperative hemodilution is longer with PEG-conjugated human serum albumin than with HES 130/0.4: a microvascular perspective. Crit Care 2008 0.97
5 Influence of the chemistry of conjugation of poly(ethylene glycol) to Hb on the oxygen-binding and solution properties of the PEG-Hb conjugate. Biochem J 2005 0.92
6 Microvascular effects following treatment with polyethylene glycol-albumin in lipopolysaccharide-induced endotoxemia. Crit Care Med 2006 0.89
7 Volume resuscitation from hemorrhagic shock with albumin and hexaPEGylated human serum albumin. Resuscitation 2008 0.88
8 PEGylation of human serum albumin: reaction of PEG-phenyl-isothiocyanate with protein. Bioconjug Chem 2008 0.87
9 Influence of intramolecular cross-links on the molecular, structural and functional properties of PEGylated haemoglobin. Biochem J 2007 0.87
10 Purification and molecular analysis of hemoglobin by high-performance liquid chromatography. Methods Mol Med 2003 0.86
11 PEGylation of Val-1(alpha) destabilizes the tetrameric structure of hemoglobin. Biochemistry 2009 0.86
12 UV resonance Raman study of beta93-modified hemoglobin A: chemical modifier-specific effects and added influences of attached poly(ethylene glycol) chains. Biochemistry 2002 0.85
13 Extension arm facilitated pegylation of alphaalpha-hemoglobin with modifications targeted exclusively to amino groups: functional and structural advantages of free Cys-93(beta) in the PEG-Hb adduct. Bioconjug Chem 2009 0.85
14 Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways. Biochemistry 2004 0.84
15 Microvascular PO2 during extreme hemodilution with hemoglobin site specifically PEGylated at Cys-93(beta) in hamster window chamber. Am J Physiol Heart Circ Physiol 2004 0.84
16 PEG-albumin supraplasma expansion is due to increased vessel wall shear stress induced by blood viscosity shear thinning. Am J Physiol Heart Circ Physiol 2012 0.84
17 Molecular modeling studies of surface decoration of hemoglobin by maleimide PEG. Artif Cells Blood Substit Immobil Biotechnol 2006 0.83
18 Autoxidation of the site-specifically PEGylated hemoglobins: role of the PEG chains and the sites of PEGylation in the autoxidation. Biochemistry 2008 0.82
19 Packing density of the PEG-shell in PEG-albumins: PEGylation induced viscosity and COP are inverse correlate of packing density. Artif Cells Blood Substit Immobil Biotechnol 2011 0.80
20 Hexa-thiocarbamoyl phenyl PEG5K Hb: vasoactivity and structure: influence of rigidity of the conjugation linkage on the PEGylation induced plasma expander-like solution properties of PEG-Hb adducts. Protein J 2009 0.79
21 Surface decoration of red blood cells with maleimidophenyl-polyethylene glycol facilitated by thiolation with iminothiolane: an approach to mask A, B, and D antigens to generate universal red blood cells. Transfusion 2005 0.78
22 Solubility measurement of the sickle polymer. Methods Mol Med 2003 0.78
23 PEGylation of αα-Hb using succinimidyl propionic acid PEG 5K: Conjugation chemistry and PEG shell structure dictate respectively the oxygen affinity and resuscitation fluid like properties of PEG αα-Hbs. Artif Cells Nanomed Biotechnol 2014 0.78
24 Analysis of functionalization of methoxy-PEG as maleimide-PEG. Anal Biochem 2007 0.77
25 Non-conservative surface decoration of hemoglobin: influence of neutralization of positive charges at PEGylation sites on molecular and functional properties of PEGylated hemoglobin. Biochim Biophys Acta 2008 0.77
26 Role of extension arm in PEG-Hb conjugates on the stability of the tetramer: non-conservative EAF maleimide thio-PEG mediated PEGylation. Artif Cells Blood Substit Immobil Biotechnol 2008 0.77
27 Induced plasma expander-like properties as a function of PEG-chains on extension arm facilitated PEGylation of albumin: "mushroom to brush-like" conformational transition of the PEG-albumin conjugate. Artif Cells Blood Substit Immobil Biotechnol 2009 0.77
28 Combining the influence of two low O2 affinity-inducing chemical modifications of the central cavity of hemoglobin. Biochemistry 2007 0.77
29 Thiolation mediated pegylation platform to generate functional universal red blood cells. Artif Cells Blood Substit Immobil Biotechnol 2007 0.76
30 Supra-plasma expanders: the future of treating blood loss and anemia without red cell transfusions? J Infus Nurs 2015 0.76
31 Tissue oxidative metabolism after extreme hemodilution with PEG-conjugated hemoglobin. J Appl Physiol (1985) 2010 0.75
32 Hemoglobin Einstein: semisynthetic deletion in the B-helix of the alpha-chain. Protein Sci 2004 0.75
33 Plasma expander and blood storage effects on capillary perfusion in transfusion after hemorrhage. Transfusion 2012 0.75
34 PEG-albumin plasma expansion increases expression of MCP-1 evidencing increased circulatory wall shear stress: an experimental study. PLoS One 2012 0.75
35 Semisynthetic hybrid biopolymers for non-pharmacological intervention of the microcirculation. Curr Drug Metab 2013 0.75
36 Increased inter dimeric interaction of oxy hemoglobin is necessary for attenuation of reductive pegylation promoted dissociation of tetramer. Artif Cells Blood Substit Immobil Biotechnol 2010 0.75