Published in J Biol Chem on January 04, 2002
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. J Cell Biol (2004) 1.89
Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells. Cell Div (2006) 1.38
Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A. Mol Cell Biol (2004) 1.31
Architecture of replication compartments formed during Epstein-Barr virus lytic replication. J Virol (2005) 1.31
Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein-Barr virus replication compartments. J Virol (2009) 1.25
Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis. Mol Cell Biol (2004) 1.23
Genomic instability in cancer. Cold Spring Harb Perspect Biol (2013) 1.23
NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin. Mol Biol Cell (2004) 1.21
Human Mcm proteins at a replication origin during the G1 to S phase transition. Nucleic Acids Res (2002) 1.19
The full-length protein encoded by human cytomegalovirus gene UL117 is required for the proper maturation of viral replication compartments. J Virol (2008) 1.18
Functional interactions of DNA topoisomerases with a human replication origin. EMBO J (2007) 1.14
Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication. J Virol (2006) 1.13
Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer. Prostate (2012) 1.11
Ubiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosis. J Cell Sci (2006) 1.01
Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila. EMBO J (2003) 0.95
TIF1 Represses rDNA replication initiation, but promotes normal S phase progression and chromosome transmission in Tetrahymena. Mol Biol Cell (2005) 0.91
The Cyclin-dependent kinase inhibitor Dacapo promotes genomic stability during premeiotic S phase. Mol Biol Cell (2009) 0.88
Characterization of a novel origin recognition complex-like complex: implications for DNA recognition, cell cycle control, and locus-specific gene amplification. Mol Cell Biol (2003) 0.88
Relationship between DNA replication and the nuclear matrix. Genes Cells (2012) 0.88
Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells. Nucleic Acids Res (2010) 0.87
Butyrate induced cell cycle arrest in bovine cells through targeting gene expression relevant to DNA replication apparatus. Gene Regul Syst Bio (2008) 0.86
Homeotic proteins participate in the function of human-DNA replication origins. Nucleic Acids Res (2010) 0.85
Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase. Cell Cycle (2011) 0.84
Site-specific interaction of the murine pre-replicative complex with origin DNA: assembly and disassembly during cell cycle transit and differentiation. Nucleic Acids Res (2007) 0.83
The clustering of CpG islands may constitute an important determinant of the 3D organization of interphase chromosomes. Epigenetics (2014) 0.80
Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage. Aging Cell (2015) 0.79
Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication. Cell Cycle (2015) 0.79
Regulation of the g1/s transition in hepatocytes: involvement of the cyclin-dependent kinase cdk1 in the DNA replication. Int J Hepatol (2012) 0.79
Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner. Nucleic Acids Res (2003) 0.79
Proteins of the origin recognition complex (ORC) and DNA topoisomerases on mammalian chromatin. BMC Mol Biol (2009) 0.75
The Non-Canonical Role of Aurora-A in DNA Replication. Front Oncol (2015) 0.75
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature (2012) 3.08
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat Cell Biol (2005) 2.41
Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding. J Biol Chem (2004) 1.91
Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins. Cancer Sci (2007) 1.90
Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells. Biochem Biophys Res Commun (2002) 1.89
Retracted The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. Cell (2003) 1.88
Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment. J Biol Chem (2004) 1.86
Filament formation of MSF-A, a mammalian septin, in human mammary epithelial cells depends on interactions with microtubules. J Biol Chem (2003) 1.82
Regulation of Notch1 gene expression by p53 in epithelial cells. Mol Cell Biol (2007) 1.78
Novel cardiac precursor-like cells from human menstrual blood-derived mesenchymal cells. Stem Cells (2008) 1.68
CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma. Mol Cell Biol (2007) 1.64
Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection. J Biol Chem (2005) 1.63
Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex. Genes Dev (2004) 1.50
Structural basis for inhibition of the replication licensing factor Cdt1 by geminin. Nature (2004) 1.50
Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential. Mol Cell Biol (2005) 1.49
Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability. J Cell Sci (2006) 1.43
Menstrual blood-derived cells confer human dystrophin expression in the murine model of Duchenne muscular dystrophy via cell fusion and myogenic transdifferentiation. Mol Biol Cell (2007) 1.42
Architecture of replication compartments formed during Epstein-Barr virus lytic replication. J Virol (2005) 1.31
Successful immortalization of endometrial glandular cells with normal structural and functional characteristics. Am J Pathol (2003) 1.27
Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins. Rev Med Virol (2009) 1.27
Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates. EMBO J (2003) 1.25
Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes. Carcinogenesis (2009) 1.25
Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein-Barr virus replication compartments. J Virol (2009) 1.25
Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication. J Virol (2004) 1.22
Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. Exp Cell Res (2003) 1.21
Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex. J Biol Chem (2002) 1.20
Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT. Cancer Sci (2007) 1.18
Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway. Mol Biol Cell (2005) 1.17
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition. J Biol Chem (2009) 1.17
Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression. Cancer Res (2004) 1.16
Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres. Genes Cells (2008) 1.15
Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication. J Virol (2004) 1.15
DeltaNp63alpha repression of the Notch1 gene supports the proliferative capacity of normal human keratinocytes and cervical cancer cells. Cancer Res (2010) 1.14
Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication. J Virol (2005) 1.13
Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication. J Virol (2006) 1.13
NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer. Neoplasia (2011) 1.13
Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts. J Virol (2007) 1.13
Efficient production of infectious viruses requires enzymatic activity of Epstein-Barr virus protein kinase. Virology (2009) 1.13
Immortalization of cementoblast progenitor cells with Bmi-1 and TERT. J Bone Miner Res (2004) 1.12
The human cytomegalovirus gene products essential for late viral gene expression assemble into prereplication complexes before viral DNA replication. J Virol (2011) 1.12
Postreplicative mismatch repair factors are recruited to Epstein-Barr virus replication compartments. J Biol Chem (2006) 1.10
The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis. J Virol (2007) 1.10
Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. Mol Biol Cell (2007) 1.09
E6AP-dependent degradation of DLG4/PSD95 by high-risk human papillomavirus type 18 E6 protein. J Virol (2006) 1.08
Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells. Lung Cancer (2010) 1.06
An in vitro multistep carcinogenesis model for human cervical cancer. Cancer Res (2008) 1.05
14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage. EMBO J (2010) 1.04
Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex. PLoS Pathog (2009) 1.03
Epstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-κB signaling during productive replication. J Virol (2013) 1.03
Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells. J Cell Biol (2012) 1.03
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein. J Cell Sci (2011) 1.02
DNA helicase activity in purified human RECQL4 protein. J Biochem (2009) 1.02
The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage. J Hum Genet (2006) 1.01
CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells. J Cell Sci (2010) 1.01
In vivo dynamics of EBNA1-oriP interaction during latent and lytic replication of Epstein-Barr virus. J Biol Chem (2004) 1.00
The keratin-binding protein Albatross regulates polarization of epithelial cells. J Cell Biol (2008) 0.99
Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells. J Virol (2012) 0.99
A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication. J Virol (2007) 0.98
Tetramer-assisted identification and characterization of epitopes recognized by HLA A*2402-restricted Epstein-Barr virus-specific CD8+ T cells. Blood (2002) 0.98
Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation? J Gene Med (2004) 0.97
Osteogenic properties of human myogenic progenitor cells. Mech Dev (2007) 0.96
Site-specific phosphorylation of MCM4 during the cell cycle in mammalian cells. FEBS J (2006) 0.96
P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation. Mol Biol Cell (2012) 0.96
The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome. J Virol (2012) 0.95
Mammalian Mcm2/4/6/7 complex forms a toroidal structure. Genes Cells (2003) 0.94
Transcriptional repression by sumoylation of Epstein-Barr virus BZLF1 protein correlates with association of histone deacetylase. J Biol Chem (2010) 0.94
Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites. Cell Signal (2008) 0.93
Nuclear Chk1 prevents premature mitotic entry. J Cell Sci (2011) 0.93
Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription. Virology (2009) 0.93
Genome guardian p53 and viral infections. Rev Med Virol (2012) 0.92
Peroxisome proliferator-activated receptor gamma inhibits expression of minichromosome maintenance proteins in vascular smooth muscle cells. Mol Endocrinol (2003) 0.92
TORC2, a coactivator of cAMP-response element-binding protein, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 protein. J Biol Chem (2009) 0.92
Production of prostaglandinE2 via bile acid is enhanced by trypsin and acid in normal human esophageal epithelial cells. Life Sci (2004) 0.91
Switching of EBV cycles between latent and lytic states. Rev Med Virol (2013) 0.91
Different distributions of Epstein-Barr virus early and late gene transcripts within viral replication compartments. J Virol (2013) 0.91
Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex. J Cell Sci (2012) 0.91
Spatiotemporally different DNA repair systems participate in Epstein-Barr virus genome maturation. J Virol (2011) 0.91
In vitro transformation of mesenchymal stem cells by oncogenic H-rasVal12. Biochem Biophys Res Commun (2006) 0.91
PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition. Nat Commun (2013) 0.90
Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1. J Biol Chem (2009) 0.90
Quantitative analysis of Epstein-Barr virus (EBV)-specific CD8+ T cells in patients with chronic active EBV infection. J Infect Dis (2004) 0.90
Immortalization of human myogenic progenitor cell clone retaining multipotentiality. Biochem Biophys Res Commun (2006) 0.90
Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein. J Virol (2007) 0.90
Immortalization of Epstein-Barr virus-negative human B lymphocytes with minimal chromosomal instability. Pathol Int (2006) 0.90
Translocation and stability of replicative DNA helicases upon encountering DNA-protein cross-links. J Biol Chem (2013) 0.90
Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replication. J Biol Chem (2009) 0.89
Establishment of immortal normal and ataxia telangiectasia fibroblast cell lines by introduction of the hTERT gene. J Radiat Res (2002) 0.88
Establishment of immortalized human hepatocytes by introduction of HPV16 E6/E7 and hTERT as cell sources for liver cell-based therapy. Cell Transplant (2008) 0.88
Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation. Mol Cell Biol (2013) 0.88
β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5. Glycobiology (2013) 0.87
Establishment of cell lines derived from the genus Macaca through controlled expression of cell cycle regulators. J Cell Biochem (2015) 0.87
Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation. Biochem Biophys Res Commun (2008) 0.87