Published in Trends Mol Med on January 01, 2002
Intestinal inflammation targets cancer-inducing activity of the microbiota. Science (2012) 7.54
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest (2007) 2.44
Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer. Proc Natl Acad Sci U S A (2011) 1.96
Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies. World J Gastroenterol (2008) 1.79
Colorectal cancer in inflammatory bowel disease: what is the real magnitude of the risk? World J Gastroenterol (2012) 1.63
Altered glycosylation in inflammatory bowel disease: a possible role in cancer development. Glycoconj J (2003) 1.61
Vitamin D receptor negatively regulates bacterial-stimulated NF-kappaB activity in intestine. Am J Pathol (2010) 1.57
Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors. Inflamm Bowel Dis (2009) 1.53
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers. Gastroenterology (2016) 1.52
Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer. World J Gastroenterol (2006) 1.52
Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer. Br J Cancer (2004) 1.27
Microbial pathways in colonic sulfur metabolism and links with health and disease. Front Physiol (2012) 1.26
Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1. Mol Cell Biol (2007) 1.22
Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats. Carcinogenesis (2003) 1.11
Association of inflammatory markers with colorectal cancer incidence in the atherosclerosis risk in communities study. Cancer Epidemiol Biomarkers Prev (2011) 1.11
Infection, inflammation, and gastrointestinal cancer. Gut (2005) 1.07
Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger. Immunol Cell Biol (2011) 1.07
Differential microRNA expression tracks neoplastic progression in inflammatory bowel disease-associated colorectal cancer. Hum Mutat (2012) 1.07
Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response. Cancer Lett (2012) 1.06
C-reactive protein as an adverse prognostic marker for men with castration-resistant prostate cancer (CRPC): confirmatory results. Urol Oncol (2010) 1.02
The complex interplay between inflammation, the microbiota and colorectal cancer. Gut Microbes (2013) 0.98
The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine. Am J Physiol Gastrointest Liver Physiol (2010) 0.97
Plasma C-reactive protein, genetic risk score, and risk of common cancers in the Atherosclerosis Risk in Communities study. Cancer Causes Control (2013) 0.96
Persistent cyclooxygenase-2 inhibition downregulates NF-{kappa}B, resulting in chronic intestinal inflammation in the min/+ mouse model of colon tumorigenesis. Cancer Res (2010) 0.96
Colon cancer screening and surveillance in inflammatory bowel disease. Clin Endosc (2014) 0.95
IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry. Carcinogenesis (2012) 0.95
The gastrointestinal microbiota and colorectal cancer. Am J Physiol Gastrointest Liver Physiol (2014) 0.94
Inflammatory Bowel Disease-related Colorectal Cancer in the Asia-Pacific Region: Past, Present, and Future. Intest Res (2014) 0.93
Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer. Carcinogenesis (2014) 0.92
Antagonistic effects of aspirin and folic acid on inflammation markers and subsequent risk of recurrent colorectal adenomas. J Natl Cancer Inst (2009) 0.92
Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer. BMC Gastroenterol (2009) 0.91
RELP, a novel human REG-like protein with up-regulated expression in inflammatory and metaplastic gastrointestinal mucosa. Am J Pathol (2003) 0.91
Circadian disruption, Per3, and human cytokine secretion. Integr Cancer Ther (2009) 0.90
Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer. Sci Rep (2014) 0.89
Wingless homolog Wnt11 suppresses bacterial invasion and inflammation in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2011) 0.89
Has the risk of colorectal cancer in inflammatory bowel disease decreased? World J Gastroenterol (2013) 0.88
Lectin extracted from Canavalia grandiflora seeds presents potential anti-inflammatory and analgesic effects. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.88
IEX-1 deficiency protects against colonic cancer. Mol Cancer Res (2012) 0.87
Association between psoriasis and incident cancer: the Iowa's Women's Health Study. Cancer Causes Control (2011) 0.87
Colorectal cancer in patients with inflammatory bowel disease: can we predict risk? World J Gastroenterol (2012) 0.87
Deoxycholate-induced colitis is markedly attenuated in Nos2 knockout mice in association with modulation of gene expression profiles. Dig Dis Sci (2007) 0.86
Solubilized antigen of Blastocystis hominis facilitates the growth of human colorectal cancer cells, HCT116. Parasitol Res (2010) 0.86
Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma. BMC Med Genet (2007) 0.85
Common NOD2/CARD15 variants are not associated with susceptibility or the clinicopathologic characteristics of sporadic colorectal cancer in Hungarian patients. BMC Cancer (2007) 0.85
Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers. Inflamm Bowel Dis (2011) 0.85
Colorectal cancer cells - Proliferation, survival and invasion by lysophosphatidic acid. Int J Biochem Cell Biol (2010) 0.83
Backwash ileitis and the risk of colon neoplasia in ulcerative colitis patients undergoing restorative proctocolectomy. Dig Dis Sci (2013) 0.82
Wogonoside prevents colitis-associated colorectal carcinogenesis and colon cancer progression in inflammation-related microenvironment via inhibiting NF-κB activation through PI3K/Akt pathway. Oncotarget (2016) 0.81
Meta-Analysis of EMT Datasets Reveals Different Types of EMT. PLoS One (2016) 0.81
STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer. World J Gastroenterol (2014) 0.80
Colorectal cancer chemoprevention by mesalazine and its derivatives. J Biomed Biotechnol (2012) 0.80
Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nat Commun (2016) 0.80
Epithelial-to-Mesenchymal Transition of RPE Cells In Vitro Confers Increased β1,6-N-Glycosylation and Increased Susceptibility to Galectin-3 Binding. PLoS One (2016) 0.79
CARD15 mutations and colorectal cancer in a South European country. Int J Colorectal Dis (2010) 0.79
The continuing uncertainty about cancer risk in inflammatory bowel disease. Gut (2016) 0.78
p38γ MAPK is required for inflammation-associated colon tumorigenesis. Oncogene (2015) 0.78
Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells. Biologics (2008) 0.78
Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the Colon Cancer Family Registry. Carcinogenesis (2014) 0.77
Expression of polarity genes in human cancer. Cancer Inform (2015) 0.77
Identification and verification of PRDX1 as an inflammation marker for colorectal cancer progression. Am J Transl Res (2016) 0.76
Balsalazide Potentiates Parthenolide-Mediated Inhibition of Nuclear Factor-κB Signaling in HCT116 Human Colorectal Cancer Cells. Intest Res (2015) 0.76
Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology. World J Gastroenterol (2015) 0.76
Disruption of Escherichia coli Nissle 1917 K5 capsule biosynthesis, through loss of distinct kfi genes, modulates interaction with intestinal epithelial cells and impact on cell health. PLoS One (2015) 0.76
Effect of adenovirus-mediated PTEN gene on ulcerative colitis-associated colorectal cancer. Int J Colorectal Dis (2013) 0.76
Mechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer. Cancer Res Front (2016) 0.76
Circulating Beta-2 Microglobulin and Risk of Cancer: The Atherosclerosis Risk in Communities Study (ARIC). Cancer Epidemiol Biomarkers Prev (2016) 0.76
Peroxisome proliferator-activated receptor-γ (PPARγ) Pro12Ala polymorphism and colorectal cancer (CRC) risk. Int J Clin Exp Med (2015) 0.75
The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. MBio (2017) 0.75
Ulcerative colitis six years after colon cancer: only a coincidence? Int Med Case Rep J (2014) 0.75
Cyclooxygenase-2 gene polymorphisms and the risk of colorectal cancer: A population-based study. Oncol Lett (2015) 0.75
Advanced endoscopic imaging for surveillance for dysplasia and colorectal cancer in inflammatory bowel disease: could the pathologist be further helped? Saudi J Gastroenterol (2014) 0.75
MicroRNAs as Therapeutic Targets in Colitis and Colitis-Associated Cancer: Tiny Players With a Giant Impact. Gastroenterology (2015) 0.75
Transitions at CpG dinucleotides, geographic clustering of TP53 mutations and food availability patterns in colorectal cancer. PLoS One (2009) 0.75
DAC can restore expression of NALP1 to suppress tumor growth in colon cancer. Cell Death Dis (2015) 0.75
Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines. BMC Cancer (2016) 0.75
Distribution of bone-marrow-derived endothelial and immune cells in a murine colitis-associated colorectal cancer model. PLoS One (2013) 0.75
Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer. mSystems (2017) 0.75
[Polypoid dysplasia in inflammatory bowel disease: differential diagnosis and further diagnostic and therapeutic approaches]. Pathologe (2011) 0.75
Intestinal inflammation targets cancer-inducing activity of the microbiota. Science (2012) 7.54
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med (2009) 5.43
Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer. Gastroenterology (2004) 4.89
Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae. J Clin Invest (2011) 2.10
Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers. Gut (2010) 1.77
Transcriptomic analysis of the sulfate starvation response of Pseudomonas aeruginosa. J Bacteriol (2007) 1.08
Mucosal barrier, bacteria and inflammatory bowel disease: possibilities for therapy. Dig Dis (2014) 1.03
Genetic characterization indicates that a specific subpopulation of Pseudomonas aeruginosa is associated with keratitis infections. J Clin Microbiol (2011) 1.02
Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. Antimicrob Agents Chemother (2007) 1.01
A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide. Dis Model Mech (2013) 0.98
Microbial mannan inhibits bacterial killing by macrophages: a possible pathogenic mechanism for Crohn's disease. Gastroenterology (2007) 0.96
Characterization of epithelial IL-8 response to inflammatory bowel disease mucosal E. coli and its inhibition by mesalamine. Inflamm Bowel Dis (2008) 0.95
A subset of mucosa-associated Escherichia coli isolates from patients with colon cancer, but not Crohn's disease, share pathogenicity islands with urinary pathogenic E. coli. Microbiology (2008) 0.94
RNA interference: a chemist's perspective. Chem Soc Rev (2010) 0.92
Lectin-epithelial interactions in the human colon. Biochem Soc Trans (2008) 0.91
Bacteria in the pathogenesis of inflammatory bowel disease. Biochem Soc Trans (2011) 0.89
Host-bacteria interaction in inflammatory bowel disease. Br Med Bull (2008) 0.88
Inflammation-associated adherent-invasive Escherichia coli are enriched in pathways for use of propanediol and iron and M-cell translocation. Inflamm Bowel Dis (2014) 0.87
Complete genome sequence of the Crohn's disease-associated adherent-invasive Escherichia coli strain HM605. J Bacteriol (2011) 0.84
Soluble plantain fibre blocks adhesion and M-cell translocation of intestinal pathogens. J Nutr Biochem (2012) 0.81
An N-terminal truncated form of Orp150 is a cytoplasmic ligand for the anti-proliferative mushroom Agaricus bisporus lectin and is required for nuclear localization sequence-dependent nuclear protein import. J Biol Chem (2002) 0.80
IBD: microbiota manipulation through diet and modified bacteria. Dig Dis (2014) 0.76
Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D. Inflamm Bowel Dis (2015) 0.75
Lessons from diversion studies and antibacterial interventions. Dig Dis (2012) 0.75