Published in Nat Cell Biol on February 01, 2002
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Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol Mol Biol Rev (2011) 5.02
Calcium at fertilization and in early development. Physiol Rev (2006) 1.76
Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis. Mol Cell Biol (2002) 1.57
Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition. Mol Cell Biol (2005) 1.56
Akt: a double-edged sword in cell proliferation and genome stability. J Oncol (2012) 1.44
Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling. Oncogene (2008) 1.31
Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis. Mol Cell Biol (2003) 1.23
MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. Mol Cell Biol (2006) 1.23
Chronic AMD3100 antagonism of SDF-1alpha-CXCR4 exacerbates cardiac dysfunction and remodeling after myocardial infarction. J Mol Cell Cardiol (2010) 1.23
Mos is not required for the initiation of meiotic maturation in Xenopus oocytes. EMBO J (2002) 1.21
Wee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumption. J Cell Biol (2010) 1.21
The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase. Proc Natl Acad Sci U S A (2003) 1.20
Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation. EMBO J (2006) 1.17
The Polo-like kinase Plx1 interacts with and inhibits Myt1 after fertilization of Xenopus eggs. EMBO J (2005) 1.11
Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factor. Nat Commun (2012) 1.10
Distinct regulators for Plk1 activation in starfish meiotic and early embryonic cycles. EMBO J (2003) 1.09
Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A. Proc Natl Acad Sci U S A (2002) 1.08
Dysregulation of X-linked gene expression in Klinefelter's syndrome and association with verbal cognition. Am J Med Genet B Neuropsychiatr Genet (2007) 1.07
Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit. J Cell Biol (2008) 0.97
Akt phosphorylation at Ser473 predicts benefit of paclitaxel chemotherapy in node-positive breast cancer. J Clin Oncol (2010) 0.96
Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression. Neoplasia (2008) 0.95
Cyclin aggregation and robustness of bio-switching. Mol Biol Cell (2003) 0.92
Drosophila myt1 is the major cdk1 inhibitory kinase for wing imaginal disc development. Genetics (2008) 0.91
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A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways. BMC Complement Altern Med (2013) 0.88
Localization and dynamics of Cdc2-cyclin B during meiotic reinitiation in starfish oocytes. Mol Biol Cell (2003) 0.87
Protein kinase B/Akt is essential for the insulin- but not progesterone-stimulated resumption of meiosis in Xenopus oocytes. Biochem J (2003) 0.87
Regulation of intracellular pH by p90Rsk-dependent activation of an Na(+)/H(+) exchanger in starfish oocytes. J Biol Chem (2010) 0.85
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia. Mol Pharmacol (2008) 0.85
Involvement of polo-like kinase 1 (Plk1) in mitotic arrest by inhibition of mitogen-activated protein kinase-extracellular signal-regulated kinase-ribosomal S6 kinase 1 (MEK-ERK-RSK1) cascade. J Biol Chem (2012) 0.84
c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer. Mol Cell Biol (2009) 0.84
An IGF1/insulin receptor substrate-1 pathway stimulates a mitotic kinase (cdk1) in the uterine epithelium during the proliferative response to estradiol. J Endocrinol (2010) 0.84
Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. Cell Rep (2015) 0.84
Cyclin B-Cdk1 inhibits protein phosphatase PP2A-B55 via a Greatwall kinase-independent mechanism. J Cell Biol (2014) 0.83
Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine? World J Gastroenterol (2015) 0.82
Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina. PLoS One (2013) 0.82
MicroRNA-126 is down-regulated in human esophageal squamous cell carcinoma and inhibits the proliferation and migration in EC109 cell via PI3K/AKT signaling pathway. Int J Clin Exp Pathol (2015) 0.82
Entry into mitosis: a solution to the decades-long enigma of MPF. Chromosoma (2015) 0.82
Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models. Mol Cancer Ther (2014) 0.80
P53 and p38 MAPK pathways are involved in MONCPT-induced cell cycle G2/M arrest in human non-small cell lung cancer A549. J Cancer Res Clin Oncol (2009) 0.79
Guanine nucleotides in the meiotic maturation of starfish oocytes: regulation of the actin cytoskeleton and of Ca(2+) signaling. PLoS One (2009) 0.77
Two new competing pathways establish the threshold for cyclin-B-Cdk1 activation at the meiotic G2/M transition. J Cell Sci (2016) 0.75
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets. Proc Natl Acad Sci U S A (2010) 2.94
Stomagen positively regulates stomatal density in Arabidopsis. Nature (2009) 2.31
Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein. Nature (2004) 2.26
Long-distance, graft-transmissible action of Arabidopsis FLOWERING LOCUS T protein to promote flowering. Plant Cell Physiol (2008) 1.79
Clinical diagnostic criteria of IgG4-related sclerosing cholangitis 2012. J Hepatobiliary Pancreat Sci (2012) 1.72
Central cell-derived peptides regulate early embryo patterning in flowering plants. Science (2014) 1.66
Identification of a novel RNA silencing suppressor, NSs protein of Tomato spotted wilt virus. FEBS Lett (2002) 1.66
Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis. Nature (2007) 1.64
Activation of a Rac GTPase by the NLR family disease resistance protein Pit plays a critical role in rice innate immunity. Cell Host Microbe (2010) 1.38
Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer. J Mol Med (Berl) (2003) 1.37
Phosphorylation of Erp1 by p90rsk is required for cytostatic factor arrest in Xenopus laevis eggs. Nature (2007) 1.37
Neural progenitor cells regulate microglia functions and activity. Nat Neurosci (2012) 1.34
Therapeutic potential of a fully human monoclonal antibody against influenza A virus M2 protein. Antiviral Res (2008) 1.30
MOSAIC FLORAL ORGANS1, an AGL6-like MADS box gene, regulates floral organ identity and meristem fate in rice. Plant Cell (2009) 1.28
Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis. J Neurosci (2011) 1.23
Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation. J Neurosci (2003) 1.16
Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs. Proc Natl Acad Sci U S A (2005) 1.11
Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factor. Nat Commun (2012) 1.10
Enhanced apoptosis and tumor regression induced by a direct agonist antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2. Clin Cancer Res (2005) 1.09
Inflorescence meristem identity in rice is specified by overlapping functions of three AP1/FUL-like MADS box genes and PAP2, a SEPALLATA MADS box gene. Plant Cell (2012) 1.09
Disease-related potential of mutations in transcriptional cofactors CREB-binding protein and p300 in leukemias. Cancer Lett (2004) 1.09
Distinct regulators for Plk1 activation in starfish meiotic and early embryonic cycles. EMBO J (2003) 1.09
Light-cone-like spreading of correlations in a quantum many-body system. Nature (2012) 1.09
Bayesian approach to MSD-based analysis of particle motion in live cells. Biophys J (2012) 1.08
Emi1-mediated M-phase arrest in Xenopus eggs is distinct from cytostatic factor arrest. Proc Natl Acad Sci U S A (2004) 1.07
Refunctionalization of the ancient rice blast disease resistance gene Pit by the recruitment of a retrotransposon as a promoter. Plant J (2008) 1.06
The 'Higgs' amplitude mode at the two-dimensional superfluid/Mott insulator transition. Nature (2012) 1.05
Observation of spatially ordered structures in a two-dimensional Rydberg gas. Nature (2012) 1.05
Single-spin addressing in an atomic Mott insulator. Nature (2011) 1.04
Unequal genetic redundancy of rice PISTILLATA orthologs, OsMADS2 and OsMADS4, in lodicule and stamen development. Plant Cell Physiol (2008) 1.03
The NMR structure of stomagen reveals the basis of stomatal density regulation by plant peptide hormones. Nat Commun (2011) 1.03
Production of human monoclonal and polyclonal antibodies in TransChromo animals. Cloning Stem Cells (2002) 1.03
Complement C1q regulates LPS-induced cytokine production in bone marrow-derived dendritic cells. Eur J Immunol (2004) 1.02
Interleukin-1beta has a role in cerebral cortical state-dependent electroencephalographic slow-wave activity. Sleep (2005) 1.02
A case of autoimmune pancreatitis responding to steroid therapy. Evidence of histologic recovery. Pancreatology (2002) 1.01
A role of OsGA20ox1 , encoding an isoform of gibberellin 20-oxidase, for regulation of plant stature in rice. Plant Mol Biol (2004) 1.01
Leaf oil body functions as a subcellular factory for the production of a phytoalexin in Arabidopsis. Plant Physiol (2013) 1.00
Giant coronary aneurysm in a patient with systemic lupus erythematosus. Intern Med (2009) 0.99
LAX PANICLE2 of rice encodes a novel nuclear protein and regulates the formation of axillary meristems. Plant Cell (2011) 0.98
Ectopic expression of an esterase, which is a candidate for the unidentified plant cutinase, causes cuticular defects in Arabidopsis thaliana. Plant Cell Physiol (2009) 0.97
Catalytic inactivation of human phospholipase D2 by a naturally occurring Gly901Asp mutation. Arch Med Res (2006) 0.97
APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs. Dev Biol (2005) 0.96
Saccharomyces cerevisiae SSD1 orthologues are essential for host infection by the ascomycete plant pathogens Colletotrichum lagenarium and Magnaporthe grisea. Mol Microbiol (2007) 0.95
The tetraspanin CD9 modulates epidermal growth factor receptor signaling in cancer cells. J Cell Physiol (2008) 0.95
A tumour-associated DEAD-box protein, rck/p54 exhibits RNA unwinding activity toward c-myc RNAs in vitro. Genes Cells (2003) 0.95
Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and/or threonine rich oligopeptides in proteins. Curr Protein Pept Sci (2008) 0.95
Insertion of cellular sequence and RNA recombination in the structural protein coding region of cytopathogenic bovine viral diarrhoea virus. J Gen Virol (2003) 0.95
CD9-mediated activation of the p46 Shc isoform leads to apoptosis in cancer cells. J Cell Sci (2004) 0.94
Fulminant septicemia of Bacillus cereus resistant to carbapenem in a patient with biphenotypic acute leukemia. J Infect Chemother (2008) 0.94
Significance of measurement of high-sensitivity C-reactive protein in acute pancreatitis. J Gastroenterol (2002) 0.92
[Anesthetic management of a patient with dilated cardiomyopathy for left ventricular pacing lead insertion under video-assisted thoracic surgery]. Masui (2002) 0.92
Insertion in the coding region of the movement protein improves stability of the plasmid encoding a tomato mosaic virus-based expression vector. Arch Virol (2008) 0.92
Involvement of Mos-MEK-MAPK pathway in cytostatic factor (CSF) arrest in eggs of the parthenogenetic insect, Athalia rosae. Mech Dev (2008) 0.92
The use of axial reconstructed images from three-dimensional MRI datasets for morphological diagnosis of meniscal tears of the knee. Arch Orthop Trauma Surg (2005) 0.92
A host small GTP-binding protein ARL8 plays crucial roles in tobamovirus RNA replication. PLoS Pathog (2011) 0.90
The systemic administration of lethal toxin achieves a growth delay of human melanoma and neuroblastoma xenografts: assessment of receptor contribution. Int J Oncol (2008) 0.90
Superior mesenteric artery syndrome caused by huge mycotic abdominal aortic aneurysm. Intern Med (2009) 0.89
A single starfish Aurora kinase performs the combined functions of Aurora-A and Aurora-B in human cells. J Cell Sci (2010) 0.89
Orexin A decreases ketamine-induced anesthesia time in the rat: the relevance to brain noradrenergic neuronal activity. Anesth Analg (2009) 0.88
Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase. EMBO J (2006) 0.87
Successful treatment of duodenal myeloid sarcoma with allogeneic bone marrow transplantation and additional radiotherapy. Intern Med (2012) 0.87
Localization and dynamics of Cdc2-cyclin B during meiotic reinitiation in starfish oocytes. Mol Biol Cell (2003) 0.87
Exploring the length of the common channel of pancreaticobiliary maljunction on magnetic resonance cholangiopancreatography. J Hepatobiliary Pancreat Sci (2014) 0.87
Heterochronic activation of VEGF signaling and the evolution of the skeleton in echinoderm pluteus larvae. Evol Dev (2012) 0.86
Coordinated regulation of M phase exit and S phase entry by the Cdc2 activity level in the early embryonic cell cycle. Dev Biol (2002) 0.86
HvCEBiP, a gene homologous to rice chitin receptor CEBiP, contributes to basal resistance of barley to Magnaporthe oryzae. BMC Plant Biol (2010) 0.86
A novel eukaryote-made thermostable DNA polymerase which is free from bacterial DNA contamination. J Clin Microbiol (2011) 0.85
S-LOCUS EARLY FLOWERING 3 is exclusively present in the genomes of short-styled buckwheat plants that exhibit heteromorphic self-incompatibility. PLoS One (2012) 0.85
Automated NMR structure determination of stereo-array isotope labeled ubiquitin from minimal sets of spectra using the SAIL-FLYA system. J Biomol NMR (2009) 0.85
Construction of a BAC library for buckwheat genome research - an application to positional cloning of agriculturally valuable traits. Genes Genet Syst (2008) 0.85
Start of the embryonic cell cycle is dually locked in unfertilized starfish eggs. Development (2009) 0.84
Involvement of two rice ETHYLENE INSENSITIVE3-LIKE genes in wound signaling. Mol Genet Genomics (2009) 0.84
Demyelinating neuropathy and autoimmune hemolytic anemia in a patient with pancreatic cancer. Intern Med (2012) 0.84
p90Rsk is required for G1 phase arrest in unfertilized starfish eggs. Development (2006) 0.83
Cyclin B-Cdk1 inhibits protein phosphatase PP2A-B55 via a Greatwall kinase-independent mechanism. J Cell Biol (2014) 0.83
Cyclin E2 is required for embryogenesis in Xenopus laevis. Dev Biol (2007) 0.82
Human DEAD-box/RNA unwindase rck/p54 contributes to maintenance of cell growth by affecting cell cycle in cultured cells. Int J Oncol (2006) 0.82
Evolutionary relationship and structural characterization of the EPF/EPFL gene family. PLoS One (2013) 0.82
[TURP syndrome with severe hyponatremia (98 mEq x l(-1)): a report of a case]. Masui (2010) 0.82
SHPS-1 negatively regulates integrin alphaIIbbeta3 function through CD47 without disturbing FAK phosphorylation. J Thromb Haemost (2005) 0.82
Localized relapse in bone marrow in a posttransplantation patient with t(6;9) acute myeloid leukemia. Int J Hematol (2003) 0.81
Epstein-Barr virus-associated post-transplant lymphoproliferative disorders after allogeneic peripheral blood stem cell transplantation for Hodgkin-like adult T-cell leukemia/lymphoma. Int J Hematol (2011) 0.81
Pancreatic regeneration after ethionine-induced acute pancreatitis in rats lacking pancreatic CCK-A receptor gene expression. J Gastroenterol (2003) 0.81
A new method for longitudinally increasing the internal jugular vein diameter during ultrasound-guided cannulation. Anesth Analg (2012) 0.81
Interleukin-8 promotes non-rapid eye movement sleep in rabbits and rats. J Sleep Res (2004) 0.80
Cyclin B-cdk1 controls pronuclear union in interphase. Curr Biol (2008) 0.80
Gastrointestinal disorders in anaphylaxis. Intern Med (2007) 0.80
Stable-isotope labeling using an inducible viral infection system in suspension-cultured plant cells. J Biomol NMR (2008) 0.80
PDK1 is required for the hormonal signaling pathway leading to meiotic resumption in starfish oocytes. Dev Biol (2004) 0.80
Interaction between orexinergic neurons and NMDA receptors in the control of locus coeruleus-cerebrocortical noradrenergic activity of the rat. Brain Res (2008) 0.80
Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. Biochem Biophys Res Commun (2003) 0.80