Published in J Cell Biol on January 21, 2002
Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol (2003) 6.35
The fifth adaptor protein complex. PLoS Biol (2011) 2.94
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J Cell Biol (2004) 2.76
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins. Mol Biol Cell (2005) 1.99
HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with alpha-adaptin. J Biol Chem (2009) 1.89
Comparative proteomics of clathrin-coated vesicles. J Cell Biol (2006) 1.83
Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes. Mol Biol Cell (2002) 1.69
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes. Mol Biol Cell (2006) 1.64
The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin. EMBO J (2003) 1.58
Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments. Proc Natl Acad Sci U S A (2005) 1.47
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. J Biol Chem (2008) 1.45
Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release. Proc Natl Acad Sci U S A (2009) 1.42
Regulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP-3. FASEB J (2008) 1.40
Identification of a homozygous deletion in the AP3B1 gene causing Hermansky-Pudlak syndrome, type 2. Blood (2006) 1.28
A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction. PLoS Pathog (2012) 1.21
The aftiphilin/p200/gamma-synergin complex. Mol Biol Cell (2005) 1.19
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα. Mol Biol Cell (2013) 1.08
Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain. Mol Biol Cell (2004) 1.08
Regulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3. Proc Natl Acad Sci U S A (2006) 1.06
The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome. Am J Respir Crit Care Med (2012) 1.06
Two patients with Hermansky Pudlak syndrome type 2 and novel mutations in AP3B1. Haematologica (2009) 1.03
Adaptor protein-3 (AP-3) complex mediates the biogenesis of acidocalcisomes and is essential for growth and virulence of Trypanosoma brucei. J Biol Chem (2011) 1.03
Adaptin evolution in kinetoplastids and emergence of the variant surface glycoprotein coat in African trypanosomatids. Mol Phylogenet Evol (2013) 1.02
The clathrin adaptor complexes as a paradigm for membrane-associated allostery. Protein Sci (2013) 1.02
The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2. Blood (2013) 0.97
AP-1 and clathrin are essential for secretory granule biogenesis in Drosophila. Mol Biol Cell (2011) 0.96
Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex. Dev Cell (2012) 0.96
Disabled-2 protein facilitates assembly polypeptide-2-independent recruitment of cystic fibrosis transmembrane conductance regulator to endocytic vesicles in polarized human airway epithelial cells. J Biol Chem (2012) 0.91
AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis. Mol Biol Cell (2007) 0.91
AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway. Mol Biol Cell (2012) 0.89
C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules. PLoS One (2012) 0.88
New insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protists. Int Rev Cell Mol Biol (2013) 0.87
Molecular and functional basis for the scaffolding role of the p50/dynamitin subunit of the microtubule-associated dynactin complex. J Biol Chem (2010) 0.87
Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target. Commun Integr Biol (2012) 0.86
Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes. J Biol Chem (2014) 0.85
Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease. Hum Mol Genet (2015) 0.85
The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells. J Clin Invest (2009) 0.84
Lysosomal localization of GLUT8 in the testis--the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction. FEBS J (2009) 0.83
Metazoan cell biology of the HOPS tethering complex. Cell Logist (2011) 0.81
Widespread dysregulation of peptide hormone release in mice lacking adaptor protein AP-3. PLoS Genet (2013) 0.80
A single β adaptin contributes to AP1 and AP2 complexes and clathrin function in Dictyostelium. Traffic (2011) 0.80
Palmitoylation of protease-activated receptor-1 regulates adaptor protein complex-2 and -3 interaction with tyrosine-based motifs and endocytic sorting. J Biol Chem (2013) 0.80
Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis. Mol Biol Cell (2013) 0.79
AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes. PLoS One (2012) 0.79
SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci (2015) 0.78
Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes. Transl Psychiatry (2013) 0.78
From all to (nearly) none: Tracing adaptin evolution in Fungi. Cell Logist (2014) 0.78
Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2. eNeuro (2016) 0.78
Adaptor protein complexes AP-1 and AP-3 are required by the HHV-7 Immunoevasin U21 for rerouting of class I MHC molecules to the lysosomal compartment. PLoS One (2014) 0.76
Adaptor protein-3: A key player in RBL-2H3 mast cell mediator release. PLoS One (2017) 0.75
Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster. PLoS One (2015) 0.75
Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Cell Rep (2016) 0.75
Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting. J Cell Biol (2017) 0.75
Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor. Mol Cell (1999) 4.67
mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors. EMBO J (2000) 4.06
Adaptor-related proteins. Curr Opin Cell Biol (2001) 3.60
Association of the AP-3 adaptor complex with clathrin. Science (1998) 3.42
100-kD coated vesicle proteins: molecular heterogeneity and intracellular distribution studied with monoclonal antibodies. J Cell Biol (1987) 3.33
The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell (1997) 3.30
Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin. Proc Natl Acad Sci U S A (2000) 3.09
Characterization of the adaptor-related protein complex, AP-3. J Cell Biol (1997) 2.76
Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron (1998) 2.73
Syntaxin 6 functions in trans-Golgi network vesicle trafficking. Mol Biol Cell (1997) 2.70
A novel adaptor-related protein complex. J Cell Biol (1996) 2.69
Immunofluorescent localization of 100K coated vesicle proteins. J Cell Biol (1986) 2.55
Targeting signals and subunit interactions in coated vesicle adaptor complexes. J Cell Biol (1995) 2.45
The yeast adaptor protein complex, AP-3, is essential for the efficient delivery of alkaline phosphatase by the alternate pathway to the vacuole. J Cell Biol (1997) 2.32
Characterization of a fourth adaptor-related protein complex. Mol Biol Cell (1999) 2.27
The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals. J Biol Chem (1998) 2.21
A function for the AP3 coat complex in synaptic vesicle formation from endosomes. Cell (1998) 2.14
Adaptor complex-independent clathrin function in yeast. Mol Biol Cell (1999) 2.10
Suppressors of YCK-encoded yeast casein kinase 1 deficiency define the four subunits of a novel clathrin AP-like complex. EMBO J (1997) 2.10
The beta3A subunit gene (Ap3b1) of the AP-3 adaptor complex is altered in the mouse hypopigmentation mutant pearl, a model for Hermansky-Pudlak syndrome and night blindness. Hum Mol Genet (1999) 2.09
The structure and function of the beta 2-adaptin appendage domain. EMBO J (2000) 2.06
Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein. Cell (1995) 1.81
A conserved clathrin assembly motif essential for synaptic vesicle endocytosis. J Neurosci (2000) 1.75
The mammalian AP-3 adaptor-like complex mediates the intracellular transport of lysosomal membrane glycoproteins. J Biol Chem (1998) 1.68
Early embryonic death of mice deficient in gamma-adaptin. J Biol Chem (1999) 1.64
Functional domain mapping of the clathrin-associated adaptor medium chains mu1 and mu2. J Biol Chem (1997) 1.58
Molecular characterization of the protein encoded by the Hermansky-Pudlak syndrome type 1 gene. J Biol Chem (2000) 1.51
Gamma subunit of the AP-1 adaptor complex binds clathrin: implications for cooperative binding in coated vesicle assembly. Mol Biol Cell (2001) 1.41
Assembly and targeting of adaptin chimeras in transfected cells. J Cell Biol (1993) 1.40
The alpha chain of the AP-2 adaptor is a clathrin binding subunit. J Biol Chem (1995) 1.35
Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet. EMBO J (1997) 1.34
The assembly of AP-3 adaptor complex-containing clathrin-coated vesicles on synthetic liposomes. Mol Biol Cell (2000) 1.25
Neuroendocrine synaptic vesicles are formed in vitro by both clathrin-dependent and clathrin-independent pathways. J Cell Biol (1998) 1.24
Abnormal expression and subcellular distribution of subunit proteins of the AP-3 adaptor complex lead to platelet storage pool deficiency in the pearl mouse. Blood (1999) 1.17
Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system. Biochem Biophys Res Commun (2001) 0.97
Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol (2003) 6.35
The fifth adaptor protein complex. PLoS Biol (2011) 2.94
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
EpsinR: an ENTH domain-containing protein that interacts with AP-1. Mol Biol Cell (2003) 2.04
Comparative proteomics of clathrin-coated vesicles. J Cell Biol (2006) 1.83
Functional analysis of AP-2 alpha and mu2 subunits. Mol Biol Cell (2006) 1.67
The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell (2011) 1.66
A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles. Nature (2007) 1.61
Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles. J Cell Biol (2012) 1.59
EpsinR is an adaptor for the SNARE protein Vti1b. Mol Biol Cell (2004) 1.45
Spatial and functional relationship of GGAs and AP-1 in Drosophila and HeLa cells. Traffic (2009) 1.33
HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2. Mol Biol Cell (2007) 1.32
Structural basis for binding of accessory proteins by the appendage domain of GGAs. Nat Struct Biol (2003) 1.32
Distinct and overlapping roles for AP-1 and GGAs revealed by the "knocksideways" system. Curr Biol (2012) 1.27
Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin. Mol Biol Cell (2003) 1.21
The aftiphilin/p200/gamma-synergin complex. Mol Biol Cell (2005) 1.19
A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. J Virol (2009) 1.17
A screen for endocytic motifs. Traffic (2010) 1.15
Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell (2013) 1.12
A human genome-wide screen for regulators of clathrin-coated vesicle formation reveals an unexpected role for the V-ATPase. Nat Cell Biol (2013) 1.09
Auxilin depletion causes self-assembly of clathrin into membraneless cages in vivo. Traffic (2008) 1.06
The role of cargo proteins in GGA recruitment. Traffic (2007) 1.04
CVAK104 is a novel regulator of clathrin-mediated SNARE sorting. Traffic (2007) 1.00
Genetic and phenotypic analysis of the mouse mutant mh2J, an Ap3d allele caused by IAP element insertion. Mamm Genome (2003) 0.93
Sorting of major cargo glycoproteins into clathrin-coated vesicles. Traffic (2005) 0.93
Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation. PLoS One (2013) 0.87