Role of Escherichia coli curli operons in directing amyloid fiber formation.

PubWeight™: 5.58‹?› | Rank: Top 1%

🔗 View Article (PMC 2838482)

Published in Science on February 01, 2002

Authors

Matthew R Chapman1, Lloyd S Robinson, Jerome S Pinkner, Robyn Roth, John Heuser, Marten Hammar, Staffan Normark, Scott J Hultgren

Author Affiliations

1: Department of Molecular Microbiology and Microbial Pathogenesis, Box 8230, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

Articles citing this

(truncated to the top 100)

Curli biogenesis and function. Annu Rev Microbiol (2006) 4.77

The amyloid state of proteins in human diseases. Cell (2012) 4.53

Functional amyloid formation within mammalian tissue. PLoS Biol (2006) 3.92

Amyloid fibers provide structural integrity to Bacillus subtilis biofilms. Proc Natl Acad Sci U S A (2010) 3.78

Immune activation in brain aging and neurodegeneration: too much or too little? Neuron (2009) 3.76

Biofilms. Cold Spring Harb Perspect Biol (2010) 3.10

The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation. EMBO J (2002) 2.59

Prion recognition elements govern nucleation, strain specificity and species barriers. Nature (2007) 2.57

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52

Characterization of the nanoscale properties of individual amyloid fibrils. Proc Natl Acad Sci U S A (2006) 2.46

Microanatomy at cellular resolution and spatial order of physiological differentiation in a bacterial biofilm. MBio (2013) 2.43

Prion generation in vitro: amyloid of Ure2p is infectious. EMBO J (2005) 2.42

Prions of fungi: inherited structures and biological roles. Nat Rev Microbiol (2007) 2.38

A novel class of secreted hydrophobic proteins is involved in aerial hyphae formation in Streptomyces coelicolor by forming amyloid-like fibrils. Genes Dev (2003) 2.29

An accessory protein required for anchoring and assembly of amyloid fibres in B. subtilis biofilms. Mol Microbiol (2011) 2.17

Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein. Mol Microbiol (2006) 2.14

In vitro polymerization of a functional Escherichia coli amyloid protein. J Biol Chem (2006) 2.09

The curli nucleator protein, CsgB, contains an amyloidogenic domain that directs CsgA polymerization. Proc Natl Acad Sci U S A (2007) 1.97

Atomic resolution insights into curli fiber biogenesis. Structure (2011) 1.93

Nanomechanics of functional and pathological amyloid materials. Nat Nanotechnol (2011) 1.90

Diversity, biogenesis and function of microbial amyloids. Trends Microbiol (2011) 1.86

The chaplins: a family of hydrophobic cell-surface proteins involved in aerial mycelium formation in Streptomyces coelicolor. Genes Dev (2003) 1.80

Protein fibrils in nature can enhance amyloid protein A amyloidosis in mice: Cross-seeding as a disease mechanism. Proc Natl Acad Sci U S A (2005) 1.70

The bacterial curli system possesses a potent and selective inhibitor of amyloid formation. Mol Cell (2015) 1.68

Functional amyloids composed of phenol soluble modulins stabilize Staphylococcus aureus biofilms. PLoS Pathog (2012) 1.68

Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli. Environ Microbiol (2009) 1.65

Mycobacterium tuberculosis produces pili during human infection. Proc Natl Acad Sci U S A (2007) 1.50

Transmissible proteins: expanding the prion heresy. Cell (2012) 1.49

Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria. EMBO J (2008) 1.48

The molecular basis of functional bacterial amyloid polymerization and nucleation. J Biol Chem (2008) 1.47

Global cell surface conformational shift mediated by a Candida albicans adhesin. Infect Immun (2004) 1.46

Amyloids: friend or foe? J Alzheimers Dis (2008) 1.46

Candida albicans Als adhesins have conserved amyloid-forming sequences. Eukaryot Cell (2007) 1.45

Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF. Proc Natl Acad Sci U S A (2009) 1.43

Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37. PLoS Pathog (2010) 1.41

Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria. J Neuroinflammation (2011) 1.41

The protein kingdom extended: ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation. Prog Biophys Mol Biol (2010) 1.38

Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+]. Nat Struct Mol Biol (2009) 1.35

CsgE is a curli secretion specificity factor that prevents amyloid fibre aggregation. Mol Microbiol (2011) 1.34

Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis. Crit Care (2008) 1.34

Roles of curli, cellulose and BapA in Salmonella biofilm morphology studied by atomic force microscopy. BMC Microbiol (2007) 1.33

Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG. Nature (2014) 1.31

The functional curli amyloid is not based on in-register parallel beta-sheet structure. J Biol Chem (2009) 1.30

Responses to amyloids of microbial and host origin are mediated through toll-like receptor 2. Cell Host Microbe (2009) 1.30

Role of the biofilm master regulator CsgD in cross-regulation between biofilm formation and flagellar synthesis. J Bacteriol (2011) 1.27

Extracellular polysaccharides associated with thin aggregative fimbriae of Salmonella enterica serovar enteritidis. J Bacteriol (2003) 1.26

Amyloid as a natural product. J Cell Biol (2003) 1.25

High-resolution MAS NMR analysis of PI3-SH3 amyloid fibrils: backbone conformation and implications for protofilament assembly and structure . Biochemistry (2010) 1.24

Sequence determinants of bacterial amyloid formation. J Mol Biol (2008) 1.24

Amyloid-like adhesins produced by floc-forming and filamentous bacteria in activated sludge. Appl Environ Microbiol (2008) 1.23

Cellulose as an architectural element in spatially structured Escherichia coli biofilms. J Bacteriol (2013) 1.23

Nanostructured films from hierarchical self-assembly of amyloidogenic proteins. Nat Nanotechnol (2010) 1.19

Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation. Elife (2014) 1.17

Studying the dynamics of flagella in multicellular communities of Escherichia coli by using biarsenical dyes. Appl Environ Microbiol (2009) 1.17

Escherichia coli biofilms have an organized and complex extracellular matrix structure. MBio (2013) 1.17

Iron induces bimodal population development by Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.16

Giving structure to the biofilm matrix: an overview of individual strategies and emerging common themes. FEMS Microbiol Rev (2015) 1.16

Gatekeeper residues in the major curlin subunit modulate bacterial amyloid fiber biogenesis. Proc Natl Acad Sci U S A (2009) 1.15

Amyloid fibrils: abnormal protein assembly. Prion (2008) 1.15

Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation. J Am Chem Soc (2012) 1.15

Toll-like receptors 1 and 2 cooperatively mediate immune responses to curli, a common amyloid from enterobacterial biofilms. Cell Microbiol (2010) 1.14

Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils. Mol Biochem Parasitol (2009) 1.14

Curli biogenesis: order out of disorder. Biochim Biophys Acta (2013) 1.14

BETASCAN: probable beta-amyloids identified by pairwise probabilistic analysis. PLoS Comput Biol (2009) 1.14

Curli functional amyloid systems are phylogenetically widespread and display large diversity in operon and protein structure. PLoS One (2012) 1.14

Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis. J Immunol (2008) 1.13

Strong underwater adhesives made by self-assembling multi-protein nanofibres. Nat Nanotechnol (2014) 1.11

Reconfiguring the quorum-sensing regulator SdiA of Escherichia coli to control biofilm formation via indole and N-acylhomoserine lactones. Appl Environ Microbiol (2009) 1.10

Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). Chem Rev (2014) 1.10

Polymerizing the fibre between bacteria and host cells: the biogenesis of functional amyloid fibres. Cell Microbiol (2008) 1.10

Structure of the nonameric bacterial amyloid secretion channel. Proc Natl Acad Sci U S A (2014) 1.09

Functional amyloids signal their arrival. Sci Signal (2009) 1.09

A localized multimeric anchor attaches the Caulobacter holdfast to the cell pole. Mol Microbiol (2010) 1.07

Widespread abundance of functional bacterial amyloid in mycolata and other gram-positive bacteria. Appl Environ Microbiol (2009) 1.05

Emergence and natural selection of drug-resistant prions. Mol Biosyst (2010) 1.05

Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation. Biochemistry (2011) 1.05

GlcNAc-6P levels modulate the expression of Curli fibers by Escherichia coli. J Bacteriol (2006) 1.05

Dichotomous versus palm-type mechanisms of lateral assembly of amyloid fibrils. Protein Sci (2006) 1.04

Spatial clustering of the curlin secretion lipoprotein requires curli fiber assembly. J Bacteriol (2008) 1.04

Binding with nucleic acids or glycosaminoglycans converts soluble protein oligomers to amyloid. J Biol Chem (2011) 1.04

Observation of spatial propagation of amyloid assembly from single nuclei. Proc Natl Acad Sci U S A (2011) 1.04

Milk- and solid-feeding practices and daycare attendance are associated with differences in bacterial diversity, predominant communities, and metabolic and immune function of the infant gut microbiome. Front Cell Infect Microbiol (2015) 1.04

Distinct acid resistance and survival fitness displayed by Curli variants of enterohemorrhagic Escherichia coli O157:H7. Appl Environ Microbiol (2011) 1.02

Functional amyloid: turning swords into plowshares. Prion (2010) 1.02

Dimethyl sulfoxide and ethanol elicit increased amyloid biogenesis and amyloid-integrated biofilm formation in Escherichia coli. Appl Environ Microbiol (2012) 1.02

Sum of the parts: composition and architecture of the bacterial extracellular matrix. J Mol Biol (2013) 1.01

Defined DNA sequences promote the assembly of a bacterial protein into distinct amyloid nanostructures. Proc Natl Acad Sci U S A (2007) 1.01

Amyloid-DNA Composites of Bacterial Biofilms Stimulate Autoimmunity. Immunity (2015) 1.00

Bacterial macroscopic rope-like fibers with cytopathic and adhesive properties. J Biol Chem (2010) 1.00

Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide. Biophys J (2010) 0.99

Capsular polysaccharide surrounds smooth and rugose types of Salmonella enterica serovar Typhimurium DT104. Appl Environ Microbiol (2005) 0.99

Microbial manipulation of the amyloid fold. Res Microbiol (2012) 0.98

Generating extracellular amyloid aggregates using E. coli cells. Genes Dev (2012) 0.98

PMEL: a pigment cell-specific model for functional amyloid formation. Pigment Cell Melanoma Res (2013) 0.97

Functional amyloid formation by Streptococcus mutans. Microbiology (2012) 0.97

Promiscuous cross-seeding between bacterial amyloids promotes interspecies biofilms. J Biol Chem (2012) 0.97

Escherichia coli harboring a natural IncF conjugative F plasmid develops complex mature biofilms by stimulating synthesis of colanic acid and Curli. J Bacteriol (2008) 0.97

Towards revealing the structure of bacterial inclusion bodies. Prion (2009) 0.97

Extending the usability of the phasing power of diselenide bonds: SeCys SAD phasing of CsgC using a non-auxotrophic strain. Acta Crystallogr D Biol Crystallogr (2010) 0.96

Transcriptomic analysis for genetic mechanisms of the factors related to biofilm formation in Escherichia coli O157:H7. Curr Microbiol (2011) 0.96

Articles cited by this

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A (2000) 96.90

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci (1993) 7.92

Quantification of beta-sheet amyloid fibril structures with thioflavin T. Methods Enzymol (1999) 5.89

Fibronectin binding mediated by a novel class of surface organelles on Escherichia coli. Nature (1989) 5.09

Isolation of an Escherichia coli K-12 mutant strain able to form biofilms on inert surfaces: involvement of a new ompR allele that increases curli expression. J Bacteriol (1998) 4.33

Purification and characterization of thin, aggregative fimbriae from Salmonella enteritidis. J Bacteriol (1991) 3.75

Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra. J Mol Biol (1992) 3.53

The RpoS sigma factor relieves H-NS-mediated transcriptional repression of csgA, the subunit gene of fibronectin-binding curli in Escherichia coli. Mol Microbiol (1993) 3.18

Nucleator-dependent intercellular assembly of adhesive curli organelles in Escherichia coli. Proc Natl Acad Sci U S A (1996) 3.09

Quantifying amyloid by congo red spectral shift assay. Methods Enzymol (1999) 2.09

Plasminogen, absorbed by Escherichia coli expressing curli or by Salmonella enteritidis expressing thin aggregative fimbriae, can be activated by simultaneously captured tissue-type plasminogen activator (t-PA). Mol Microbiol (1994) 2.09

Availability of the fibre subunit CsgA and the nucleator protein CsgB during assembly of fibronectin-binding curli is limited by the intracellular concentration of the novel lipoprotein CsgG. Mol Microbiol (1997) 1.98

Assembly of human contact phase proteins and release of bradykinin at the surface of curli-expressing Escherichia coli. Mol Microbiol (1996) 1.97

Thin aggregative fimbriae enhance Salmonella enteritidis biofilm formation. FEMS Microbiol Lett (1998) 1.95

Nucleator function of CsgB for the assembly of adhesive surface organelles in Escherichia coli. EMBO J (1997) 1.72

Environmental regulation of curli production in Escherichia coli. Infect Agents Dis (1993) 1.35

Crossbridges in insect flight muscles of the blowfly (Sarcophaga bullata). J Muscle Res Cell Motil (1987) 1.06

Articles by these authors

Molecular anatomy of a trafficking organelle. Cell (2006) 11.47

Intracellular bacterial biofilm-like pods in urinary tract infections. Science (2003) 7.10

Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. Proc Natl Acad Sci U S A (2006) 5.13

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments. J Cell Biol (2008) 4.66

Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12

The biology and future prospects of antivirulence therapies. Nat Rev Microbiol (2008) 3.83

An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps. Curr Biol (2006) 3.69

Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med (2007) 3.54

Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract. Proc Natl Acad Sci U S A (2006) 3.36

Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol (2002) 3.26

Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science (2004) 3.06

Dynamic actin patterns and Arp2/3 assembly at the substrate-attached surface of motile cells. Curr Biol (2004) 2.95

Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69

Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54

Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med (2002) 2.53

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52

Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili. Cell Microbiol (2007) 2.48

Bacterial adhesins in host-microbe interactions. Cell Host Microbe (2009) 2.43

Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli. J Biol Chem (2001) 2.34

Bacterial strategies for overcoming host innate and adaptive immune responses. Nat Immunol (2002) 2.33

Mycobacterium marinum escapes from phagosomes and is propelled by actin-based motility. J Exp Med (2003) 2.30

Morphological plasticity as a bacterial survival strategy. Nat Rev Microbiol (2008) 2.28

Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont. J Biol Chem (2009) 2.21

Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect Immun (2002) 2.20

Structural biology of the chaperone-usher pathway of pilus biogenesis. Nat Rev Microbiol (2009) 2.19

The Salmonella enterica subspecies I specific centisome 7 genomic island encodes novel protein families present in bacteria living in close contact with eukaryotic cells. Res Microbiol (2002) 2.18

Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17

Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med (2011) 2.16

Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15

A murine model of urinary tract infection. Nat Protoc (2009) 2.15

Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein. Mol Microbiol (2006) 2.14

Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation. Infect Immun (2006) 2.11

Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization. Infect Immun (2005) 2.10

Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells. J Exp Med (2003) 2.05

Integrin alpha(v)beta(3) on human endothelial cells binds von Willebrand factor strings under fluid shear stress. Blood (2008) 2.04

Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2003) 2.02

A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A (2006) 2.01

T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis. Immunity (2011) 2.00

Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps. Cell Microbiol (2007) 1.99

Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. Microbes Infect (2010) 1.95

Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly. Dev Cell (2006) 1.95

Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Mol Microbiol (2005) 1.90

Fiber assembly by the chaperone-usher pathway. Biochim Biophys Acta (2004) 1.89

Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection. Sci Transl Med (2013) 1.88

Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathog (2010) 1.88

Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A (2006) 1.87

Intraclonal variations among Streptococcus pneumoniae isolates influence the likelihood of invasive disease in children. J Infect Dis (2013) 1.84

Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli. PLoS Pathog (2009) 1.83

Polynucleotide phosphorylase is a global regulator of virulence and persistency in Salmonella enterica. Proc Natl Acad Sci U S A (2002) 1.83

Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. J Urol (2004) 1.82

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Mol Cell (2006) 1.81

Assembly of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand factor. Proc Natl Acad Sci U S A (2008) 1.81

Neutrophil extracellular traps: casting the NET over pathogenesis. Curr Opin Microbiol (2007) 1.80

A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. J Infect Dis (2013) 1.76

A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors. Mol Biol Cell (2006) 1.75

Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67

The structure of bacterial ParM filaments. Nat Struct Mol Biol (2007) 1.66

Functional genomic studies of uropathogenic Escherichia coli and host urothelial cells when intracellular bacterial communities are assembled. J Biol Chem (2007) 1.64

Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection. Infect Immun (2012) 1.64

Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. Cell Microbiol (2006) 1.62

Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis. Trends Microbiol (2004) 1.62

Emergence of hypervirulent mutants resistant to early clearance during systemic serotype 1 pneumococcal infection in mice and humans. J Infect Dis (2014) 1.62

Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice. Cell Microbiol (2005) 1.59

The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58

Structural correlates of cytoplasmic and chloroplast lipid body synthesis in Chlamydomonas reinhardtii and stimulation of lipid body production with acetate boost. Eukaryot Cell (2011) 1.58

Maturation of intracellular Escherichia coli communities requires SurA. Infect Immun (2006) 1.56

Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding. Proc Natl Acad Sci U S A (2009) 1.56

Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli. Infect Immun (2005) 1.55

Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55

External scaffold of spherical immature poxvirus particles is made of protein trimers, forming a honeycomb lattice. J Cell Biol (2005) 1.55

Virulence in mice of pneumococcal clonal types with known invasive disease potential in humans. J Infect Dis (2005) 1.51

Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection. Cell Host Microbe (2009) 1.51

Unusual kinetic and structural properties control rapid assembly and turnover of actin in the parasite Toxoplasma gondii. Mol Biol Cell (2005) 1.50

Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related. J Infect Dis (2008) 1.49

Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific. J Infect Dis (2012) 1.48

QseC-mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenic Escherichia coli. Mol Microbiol (2009) 1.47

A tale of two pili: assembly and function of pili in bacteria. Trends Microbiol (2010) 1.47

Divergence of quaternary structures among bacterial flagellar filaments. Science (2008) 1.46

A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments. Nucleic Acids Res (2008) 1.46

The Escherichia coli BarA-UvrY two-component system is needed for efficient switching between glycolytic and gluconeogenic carbon sources. J Bacteriol (2003) 1.44

Targeted chemical disruption of clathrin function in living cells. Mol Biol Cell (2003) 1.43

Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF. Proc Natl Acad Sci U S A (2009) 1.43

Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J Med Chem (2010) 1.40

Gastric mucosal recognition of Helicobacter pylori is independent of Toll-like receptor 4. J Infect Dis (2003) 1.39

The Legionella pneumophila PilT homologue DotB exhibits ATPase activity that is critical for intracellular growth. J Bacteriol (2004) 1.39