Published in J Am Chem Soc on February 13, 2002
Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. Microb Cell Fact (2006) 1.17
Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis. J Biol Chem (2002) 1.70
A genomics approach to the early stages of triterpene saponin biosynthesis in Medicago truncatula. Plant J (2002) 1.57
On the origins of triterpenoid skeletal diversity. Phytochemistry (2004) 1.31
Identification of 7(8) and 8(9) unsaturated adrenal steroid metabolites produced by patients with 7-dehydrosterol-delta7-reductase deficiency (Smith-Lemli-Opitz syndrome). J Steroid Biochem Mol Biol (2002) 1.24
An oxidosqualene cyclase makes numerous products by diverse mechanisms: a challenge to prevailing concepts of triterpene biosynthesis. J Am Chem Soc (2007) 1.11
The implications of 7-dehydrosterol-7-reductase deficiency (Smith-Lemli-Opitz syndrome) to neurosteroid production. Steroids (2004) 1.08
Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. Mol Biochem Parasitol (2003) 1.08
Metabolic engineering to produce sesquiterpenes in yeast. Org Lett (2003) 1.08
Arabidopsis thaliana squalene epoxidase 1 is essential for root and seed development. J Biol Chem (2007) 1.05
Chemical synthesis of 7- and 8-dehydro derivatives of pregnane-3,17alpha,20-triols, potential steroid metabolites in Smith-Lemli-Opitz syndrome. Steroids (2003) 1.03
Lanosterol biosynthesis in plants. Arch Biochem Biophys (2006) 1.01
Cloning and functional characterization of a beta-pinene synthase from Artemisia annua that shows a circadian pattern of expression. Plant Physiol (2002) 1.00
Cholesterol import by Aspergillus fumigatus and its influence on antifungal potency of sterol biosynthesis inhibitors. Antimicrob Agents Chemother (2005) 0.98
HEM dysplasia and ichthyosis are likely laminopathies and not due to 3beta-hydroxysterol Delta14-reductase deficiency. Hum Mol Genet (2007) 0.95
Mechanistic insights into triterpene synthesis from quantum mechanical calculations. Detection of systematic errors in B3LYP cyclization energies. Org Biomol Chem (2006) 0.93
Protostadienol biosynthesis and metabolism in the pathogenic fungus Aspergillus fumigatus. Org Lett (2009) 0.93
Oxidosqualene cyclase second-sphere residues profoundly influence the product profile. Chembiochem (2004) 0.91
Genome mining to identify new plant triterpenoids. J Am Chem Soc (2004) 0.90
Mutagenesis approaches to deduce structure-function relationships in terpene synthases. Nat Prod Rep (2003) 0.87
Directed evolution to generate cycloartenol synthase mutants that produce lanosterol. Org Lett (2002) 0.85
A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity. J Lipid Res (2006) 0.84
Directed evolution experiments reveal mutations at cycloartenol synthase residue His477 that dramatically alter catalysis. Org Lett (2002) 0.84
Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase. J Am Chem Soc (2005) 0.84
An effective strategy for exploring unknown metabolic pathways by genome mining. J Am Chem Soc (2013) 0.83
An Arabidopsis oxidosqualene cyclase catalyzes iridal skeleton formation by Grob fragmentation. Angew Chem Int Ed Engl (2006) 0.81
Oxidosqualene cyclase inhibitors as antimicrobial agents. J Med Chem (2003) 0.80
Plant biology. Seeing red. Science (2003) 0.80
Trinorlupeol: a major nonsterol triterpenoid in Arabidopsis. Org Lett (2008) 0.80
Stereochemistry of water addition in triterpene synthesis: the structure of arabidiol. Org Lett (2007) 0.80
Chromatographic behavior of oxygenated derivatives of cholesterol. Steroids (2003) 0.79
Enzymatic cyclization of dioxidosqualene to heterocyclic triterpenes. J Am Chem Soc (2005) 0.78
Arabidopsis camelliol C synthase evolved from enzymes that make pentacycles. Org Lett (2007) 0.78
Alternative pathways of sterol synthesis in yeast. Use of C(27) sterol tracers to study aberrant double-bond migrations and evaluate their relative importance. Steroids (2002) 0.77
The Liebermann-Burchard reaction: sulfonation, desaturation, and rearrangment of cholesterol in acid. Lipids (2007) 0.77
Structure and reactivity of the dammarenyl cation: configurational transmission in triterpene synthesis. J Org Chem (2005) 0.76
Ternary gradient elution markedly improves silver-ion high performance liquid chromatography of unsaturated sterols. Steroids (2002) 0.76
A putative precursor of isomalabaricane triterpenoids from lanosterol synthase mutants. Org Lett (2006) 0.76
Enzymatic synthesis of an indole diterpene by an oxidosqualene cyclase: mechanistic, biosynthetic, and phylogenetic implications. J Am Chem Soc (2003) 0.75
A colorimetric assay for 7-dehydrocholesterol with potential application to screening for Smith-Lemli-Opitz syndrome. Chem Phys Lipids (2002) 0.75
Programming of initial steps in bile acid synthesis by breast-feeding vs. formula-feeding in the baboon. Lipids (2003) 0.75
Mixed bioengineering-chemical synthesis approach for the efficient preparation of Δ7-dafachronic acid. Org Lett (2014) 0.75
Thermal rearrangements of spiro[2.4]hepta-1,4,6-trienes. J Org Chem (2002) 0.75
Product profile of PEN3: the last unexamined oxidosqualene cyclase in Arabidopsis thaliana. Org Lett (2009) 0.75