Published in J Biol Chem on February 11, 2002
Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2. EMBO J (2003) 2.95
Counting RAD51 proteins disassembling from nucleoprotein filaments under tension. Nature (2008) 2.21
Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats. Nat Struct Mol Biol (2007) 1.89
Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function. Nucleic Acids Res (2005) 1.71
TrwB, the coupling protein involved in DNA transport during bacterial conjugation, is a DNA-dependent ATPase. Proc Natl Acad Sci U S A (2005) 1.36
Preferential binding to branched DNA strands and strand-annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex. Nucleic Acids Res (2004) 1.23
A DNA translocation motif in the bacterial transcription--repair coupling factor, Mfd. Nucleic Acids Res (2003) 1.21
Role of the insulin-like growth factor I/insulin receptor substrate 1 axis in Rad51 trafficking and DNA repair by homologous recombination. Mol Cell Biol (2003) 1.21
RAD54 controls access to the invading 3'-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae. Nucleic Acids Res (2008) 1.21
Real-time measurements of the nucleation, growth and dissociation of single Rad51-DNA nucleoprotein filaments. Nucleic Acids Res (2007) 1.14
A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51. Nat Commun (2015) 0.98
Direct observation of twisting steps during Rad51 polymerization on DNA. Proc Natl Acad Sci U S A (2009) 0.96
RAD51 protein ATP cap regulates nucleoprotein filament stability. J Biol Chem (2012) 0.92
Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase. Nucleic Acids Res (2013) 0.91
Biochemistry of eukaryotic homologous recombination. Top Curr Genet (2007) 0.91
Rad51 polymerization reveals a new chromatin remodeling mechanism. PLoS One (2008) 0.89
Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr D Biol Crystallogr (2009) 0.86
The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament. DNA Repair (Amst) (2013) 0.85
The human Rad51 K133A mutant is functional for DNA double-strand break repair in human cells. Biochemistry (2007) 0.84
IGF-IR in neuroprotection and brain tumors. Front Biosci (Landmark Ed) (2009) 0.83
ATP-dependent nucleosome unwrapping catalyzed by human RAD51. Nucleic Acids Res (2013) 0.83
GT198 Splice Variants Display Dominant-Negative Activities and Are Induced by Inactivating Mutations. Genes Cancer (2013) 0.83
Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function. PLoS Genet (2013) 0.83
Mycobacterium tuberculosis RecA intein, a LAGLIDADG homing endonuclease, displays Mn(2+) and DNA-dependent ATPase activity. Nucleic Acids Res (2003) 0.80
Human Rad51 mediated DNA unwinding is facilitated by conditions that favour Rad51-dsDNA aggregation. BMC Biochem (2009) 0.79
Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase. Nucleic Acids Res (2014) 0.78
Archaeal genome guardians give insights into eukaryotic DNA replication and damage response proteins. Archaea (2014) 0.77
Entamoeba histolytica Dmc1 Catalyzes Homologous DNA Pairing and Strand Exchange That Is Stimulated by Calcium and Hop2-Mnd1. PLoS One (2015) 0.77
Rad51 protein from the thermotolerant yeast Pichia angusta as a typical but thermodependent member of the Rad51 family. Eukaryot Cell (2004) 0.76
Subunit interface residues F129 and H294 of human RAD51 are essential for recombinase function. PLoS One (2011) 0.76
pH-dependent activities and structural stability of loop-2-anchoring helix of RadA recombinase from Methanococcus voltae. Protein Pept Lett (2014) 0.75
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst (2004) 14.97
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol (2007) 3.03
Lynch syndrome: form, function, proteins, and basketball. Gastroenterology (2005) 2.57
hMSH4-hMSH5 recognizes Holliday Junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomes. Mol Cell (2004) 2.49
The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair. Mol Cell (2003) 2.46
Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci U S A (2010) 2.05
MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2). Proc Natl Acad Sci U S A (2010) 1.99
Exclusion of breast cancer as an integral tumor of hereditary nonpolyposis colorectal cancer. Cancer Res (2002) 1.96
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res (2004) 1.82
Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes. Am J Hum Genet (2004) 1.67
DNA mismatch repair-dependent response to fluoropyrimidine-generated damage. J Biol Chem (2004) 1.65
Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis. Mol Cell Biol (2002) 1.60
Histone fold modifications control nucleosome unwrapping and disassembly. Proc Natl Acad Sci U S A (2011) 1.60
Acetylation of histone H3 at the nucleosome dyad alters DNA-histone binding. J Biol Chem (2009) 1.56
MutS switches between two fundamentally distinct clamps during mismatch repair. Nat Struct Mol Biol (2011) 1.56
Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair. Cancer Biol Ther (2009) 1.46
Nucleosome remodeling by hMSH2-hMSH6. Mol Cell (2009) 1.36
DNA repair and tumorigenesis: lessons from hereditary cancer syndromes. Cancer Biol Ther (2002) 1.29
Nitric oxide-donating aspirin derivatives suppress microsatellite instability in mismatch repair-deficient and hereditary nonpolyposis colorectal cancer cells. Cancer Res (2007) 1.22
RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair. EMBO Rep (2009) 1.21
hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis. J Biol Chem (2011) 1.21
Frequent microsatellite instability in sporadic tumors of the upper urinary tract. Cancer Res (2002) 1.20
Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model. Cancer Prev Res (Phila) (2011) 1.19
Current and emerging trends in Lynch syndrome identification in women with endometrial cancer. Gynecol Oncol (2009) 1.19
Activation of human MutS homologs by 8-oxo-guanine DNA damage. J Biol Chem (2001) 1.19
Regulation of the nucleosome unwrapping rate controls DNA accessibility. Nucleic Acids Res (2012) 1.18
The DNA repair genes XPB and XPD defend cells from retroviral infection. Proc Natl Acad Sci U S A (2006) 1.18
Phosphorylation of histone H3(T118) alters nucleosome dynamics and remodeling. Nucleic Acids Res (2011) 1.15
Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer. Clin Cancer Res (2004) 1.13
Sequence context effect for hMSH2-hMSH6 mismatch-dependent activation. Proc Natl Acad Sci U S A (2009) 1.13
Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC). Cancer Invest (2002) 1.08
DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets. Br J Pharmacol (2009) 1.07
Biochemical characterization of the human RAD51 protein. III. Modulation of DNA binding by adenosine nucleotides. J Biol Chem (2002) 1.02
Liquid chromatography mass spectrometry profiling of histones. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 1.00
Microsatellite status and cell cycle associated markers in rectal cancer patients undergoing a combined regimen of 5-FU and CPT-11 chemotherapy and radiotherapy. Anticancer Res (2004) 1.00
hXRCC2 enhances ADP/ATP processing and strand exchange by hRAD51. J Biol Chem (2004) 1.00
HNPCC mutations in hMSH2 result in reduced hMSH2-hMSH6 molecular switch functions. Cancer Cell (2002) 0.99
A quantitative model of nucleosome dynamics. Nucleic Acids Res (2011) 0.97
The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene. Proc Natl Acad Sci U S A (2003) 0.95
Patient vs. physician as the target of educational outreach about screening for an inherited susceptibility to colorectal cancer. Genet Test (2002) 0.95
The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome. Fam Cancer (2013) 0.94
Biochemical characterization of the human RAD51 protein. II. Adenosine nucleotide binding and competition. J Biol Chem (2002) 0.94
Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6. J Biol Chem (2011) 0.93
RAD51 protein ATP cap regulates nucleoprotein filament stability. J Biol Chem (2012) 0.92
hMSH4-hMSH5 adenosine nucleotide processing and interactions with homologous recombination machinery. J Biol Chem (2007) 0.91
Defining the salt effect on human RAD51 activities. DNA Repair (Amst) (2006) 0.89
Single-molecule analysis reveals the kinetics and physiological relevance of MutL-ssDNA binding. PLoS One (2010) 0.88
Homologous recombination in eukaryotes. Prog Mol Biol Transl Sci (2012) 0.86
The base excision repair pathway is required for efficient lentivirus integration. PLoS One (2011) 0.86
Magnesium influences the discrimination and release of ADP by human RAD51. DNA Repair (Amst) (2006) 0.85
The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament. DNA Repair (Amst) (2013) 0.85
ATP-dependent nucleosome unwrapping catalyzed by human RAD51. Nucleic Acids Res (2013) 0.83
Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002. Cancer Res (2002) 0.82
PCR-based detection is unable to consistently distinguish HIV 1LTR circles. J Virol Methods (2006) 0.81
MSI-testing in hereditary non-polyposis colorectal carcinoma (HNPCC). Dis Markers (2004) 0.80
Mismatch repair protein hMSH2-hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediate. Proc Natl Acad Sci U S A (2014) 0.80
XPB mediated retroviral cDNA degradation coincides with entry to the nucleus. Virology (2010) 0.80
Real-time quantitative PCR and fast QPCR have similar sensitivity and accuracy with HIV cDNA late reverse transcripts and 2-LTR circles. J Virol Methods (2008) 0.79
The hMSH2(M688R) Lynch syndrome mutation may function as a dominant negative. Carcinogenesis (2012) 0.79
Enrichment and characterization of histones by two-dimensional hydroxyapatite/reversed-phase liquid chromatography-mass spectrometry. Anal Biochem (2009) 0.78
Subunit interface residues F129 and H294 of human RAD51 are essential for recombinase function. PLoS One (2011) 0.76