Leptin and reproduction: a review.

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J Clin Invest (2003) 2.42

Adiponectin and cancer: a systematic review. Br J Cancer (2006) 2.33

The relation of menarcheal age to obesity in childhood and adulthood: the Bogalusa heart study. BMC Pediatr (2003) 2.32

Leptin in human physiology and pathophysiology. Am J Physiol Endocrinol Metab (2011) 1.99

Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk. Cancer Res (2008) 1.28

Current knowledge of obesity's effects in the pre- and periconceptional periods and avenues for future research. Am J Obstet Gynecol (2010) 1.21

Prenatal androgen exposure programs metabolic dysfunction in female mice. J Endocrinol (2010) 1.13

Exercise induced adipokine changes and the metabolic syndrome. J Diabetes Res (2014) 1.12

Metabolic syndrome and triple-negative breast cancer: a new paradigm. Int J Breast Cancer (2011) 1.10

Duration of lactation and maternal adipokines at 3 years postpartum. Diabetes (2011) 1.04

The impact of female obesity on the outcome of fertility treatment. J Hum Reprod Sci (2010) 1.03

Partial recovery of luteal function after bariatric surgery in obese women. Fertil Steril (2008) 1.02

The role of adiponectin in reproduction: from polycystic ovary syndrome to assisted reproduction. Fertil Steril (2010) 1.01

Leptin signaling and circuits in puberty and fertility. Cell Mol Life Sci (2012) 1.01

The role of leptin in innate and adaptive immune responses. Arthritis Res Ther (2006) 0.99

Sex-specific associations between placental leptin promoter DNA methylation and infant neurobehavior. Psychoneuroendocrinology (2013) 0.98

Adiposity and sex hormones across the menstrual cycle: the BioCycle Study. Int J Obes (Lond) (2012) 0.91

Leptin as a modulator of neuroendocrine function in humans. Yonsei Med J (2012) 0.90

Hypothalamic leptin gene therapy prevents weight gain without long-term detrimental effects on bone in growing and skeletally mature female rats. J Bone Miner Res (2011) 0.88

Adipokines and insulin action: A sensitive issue. Adipocyte (2014) 0.88

Moderate weight gain does not influence bone metabolism in skeletally mature female rats. Bone (2010) 0.87

Adipokines, adiposity, and vasomotor symptoms during the menopause transition: findings from the Study of Women's Health Across the Nation. Fertil Steril (2013) 0.87

Fasting and glucose effects on pituitary leptin expression: is leptin a local signal for nutrient status? J Histochem Cytochem (2007) 0.86

Impact of obesity on infertility in women. J Turk Ger Gynecol Assoc (2015) 0.85

Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women. Obesity (Silver Spring) (2013) 0.84

Changes in serum leptin during phases of menstrual cycle of fertile women: relationship to age groups and fertility. Int J Endocrinol Metab (2012) 0.84

Chemerin: A comprehensive review elucidating the need for cardiovascular research. Pharmacol Res (2015) 0.83

Single nucleotide polymorphisms in the leptin-a gene and associations with growth traits in the orange-spotted grouper (Epinephelus coioides). Int J Mol Sci (2013) 0.82

Clinically relevant known and candidate genes for obesity and their overlap with human infertility and reproduction. J Assist Reprod Genet (2015) 0.81

The Deep Correlation between Energy Metabolism and Reproduction: A View on the Effects of Nutrition for Women Fertility. Nutrients (2016) 0.80

The impact of hyperactivity and leptin on recovery from anorexia nervosa. J Neural Transm (Vienna) (2007) 0.80

Polymorphisms of leptin-b gene associated with growth traits in orange-spotted grouper (Epinephelus coioides). Int J Mol Sci (2014) 0.79

Melatonin induces follicle maturation in Danio rerio. PLoS One (2011) 0.79

Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation. Eur J Histochem (2014) 0.79

Overt leptin response to controlled ovarian hyperstimulation negatively correlates with pregnancy outcome in in vitro fertilization--embryo transfer cycle. J Hum Reprod Sci (2012) 0.78

Interplay of pro- and anti-inflammatory cytokines to determine lipid accretion in adipocytes. Int J Obes (Lond) (2013) 0.78

Obesity and anovulatory infertility: A review. JBRA Assist Reprod (2016) 0.77

Leptin Genes in Blunt Snout Bream: Cloning, Phylogeny and Expression Correlated to Gonads Development. Int J Mol Sci (2015) 0.77

Expression of SDF-1α and leptin, and their effect on expression of angiogenic factors in mouse ovaries. Clin Exp Reprod Med (2011) 0.77

Genetic Rodent Models of Obesity-Associated Ovarian Dysfunction and Subfertility: Insights into Polycystic Ovary Syndrome. Front Endocrinol (Lausanne) (2016) 0.76

A critical view of the use of genetic tools to unveil neural circuits: the case of leptin action in reproduction. Am J Physiol Regul Integr Comp Physiol (2013) 0.76

Metabolic syndrome in breast cancer. Gland Surg (2013) 0.76

Association of assisted reproductive technology with adverse pregnancy outcomes. Iran J Reprod Med (2015) 0.76

Ovarian function in Samoan women shows stronger association with signals of energy metabolism than fat reserves. Am J Hum Biol (2013) 0.75

Selective leptin insensitivity and alterations in female-reproductive patterns linked to hyperleptinemia during infancy. PLoS One (2013) 0.75

Systemic leptin dose-dependently increases STAT3 phosphorylation within hypothalamic and hindbrain nuclei. Am J Physiol Regul Integr Comp Physiol (2014) 0.75

From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines. Mediators Inflamm (2016) 0.75

Investigating the association between prepregnancy body mass index and adverse pregnancy outcomes: a large cohort study of 536 098 Chinese pregnant women in rural China. BMJ Open (2016) 0.75

Peroxisome proliferator-activated receptor gamma signaling in human sperm physiology. Asian J Androl (2015) 0.75

Association of bovine leptin polymorphisms with energy output and energy storage traits in progeny tested Holstein-Friesian dairy cattle sires. BMC Genet (2010) 0.75

The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes. PLoS One (2015) 0.75

Leptin and its emerging role in children and adolescents. Clin Pediatr Endocrinol (2006) 0.75

Leptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal state. Am J Physiol Regul Integr Comp Physiol (2016) 0.75

The thymoprotective function of leptin is indirectly mediated via suppression of obesity. Immunology (2015) 0.75

Loss of PI3K p110α in the Adipose Tissue Results in Infertility and Delayed Puberty Onset in Male Mice. Biomed Res Int (2017) 0.75

Low expression of leptin and its association with breast cancer: A transcriptomic study. Oncol Rep (2016) 0.75

Interleukin-17 and leptin genes polymorphisms and their levels in relation to recurrent pregnancy loss in Egyptian females. Immunogenetics (2015) 0.75

Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A (2009) 6.67

Diabetes mellitus and risk of breast cancer: a meta-analysis. Int J Cancer (2007) 5.57

Recombinant human leptin in women with hypothalamic amenorrhea. N Engl J Med (2004) 4.87

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism (2012) 3.61

Dietary patterns and risk of mortality from cardiovascular disease, cancer, and all causes in a prospective cohort of women. Circulation (2008) 3.56

Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women. Circulation (2009) 3.47

Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study. J Natl Cancer Inst (2005) 3.22

Leptin in immunology. J Immunol (2005) 2.62

Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes. Diabetes Care (2004) 2.55

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J Clin Invest (2003) 2.42

Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence. Am J Clin Nutr (2007) 2.40

Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects. J Clin Endocrinol Metab (2003) 2.25

Adiponectin in insulin resistance: lessons from translational research. Am J Clin Nutr (2009) 2.22

Circulating irisin in relation to insulin resistance and the metabolic syndrome. J Clin Endocrinol Metab (2013) 2.16

Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies. J Clin Endocrinol Metab (2003) 2.09

Reproducibility of plasma and urine biomarkers among premenopausal and postmenopausal women from the Nurses' Health Studies. Cancer Epidemiol Biomarkers Prev (2010) 2.09

Plasma adiponectin concentrations and risk of incident breast cancer. J Clin Endocrinol Metab (2007) 2.07

Coffee consumption is associated with higher plasma adiponectin concentrations in women with or without type 2 diabetes: a prospective cohort study. Diabetes Care (2007) 2.06

Total and high-molecular weight adiponectin in relation to metabolic variables at baseline and in response to an exercise treatment program: comparative evaluation of three assays. Diabetes Care (2007) 2.04

The role of the IGF system in cancer: from basic to clinical studies and clinical applications. Oncology (2002) 2.03

Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women. Ann Intern Med (2008) 2.01

Narrative review: the role of leptin in human physiology: emerging clinical applications. Ann Intern Med (2010) 2.00

Sleep duration and snoring in relation to biomarkers of cardiovascular disease risk among women with type 2 diabetes. Diabetes Care (2007) 1.99

Circulating insulin and c-peptide levels and risk of breast cancer among predominately premenopausal women. Cancer Epidemiol Biomarkers Prev (2007) 1.95

Drug Insight: the role of leptin in human physiology and pathophysiology--emerging clinical applications. Nat Clin Pract Endocrinol Metab (2006) 1.88

Circulating adiponectin and endometrial cancer risk. J Clin Endocrinol Metab (2004) 1.86

Diurnal and ultradian dynamics of serum adiponectin in healthy men: comparison with leptin, circulating soluble leptin receptor, and cortisol patterns. J Clin Endocrinol Metab (2003) 1.84

Type 2 diabetes mellitus and medications for type 2 diabetes mellitus are associated with risk for and mortality from cancer in a German primary care cohort. Metabolism (2010) 1.81

Independent circadian and sleep/wake regulation of adipokines and glucose in humans. J Clin Endocrinol Metab (2005) 1.81

The role of adiponectin in cancer: a review of current evidence. Endocr Rev (2012) 1.78

Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. J Clin Endocrinol Metab (2003) 1.65

Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. Gut (2012) 1.65

Coffee drinking and risk of endometrial cancer--a population-based cohort study. Int J Cancer (2009) 1.63

Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obes Res (2003) 1.62

Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training. J Clin Endocrinol Metab (2006) 1.61

Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans with leptin sufficiency or excess. J Clin Endocrinol Metab (2004) 1.61

Relationship of leptin to bone mineralization in children and adolescents. J Clin Endocrinol Metab (2003) 1.58

Neonatal leptin levels are strongly associated with female gender, birth length, IGF-I levels and formula feeding. Clin Endocrinol (Oxf) (2005) 1.57

Recombinant methionyl human leptin therapy in replacement doses improves insulin resistance and metabolic profile in patients with lipoatrophy and metabolic syndrome induced by the highly active antiretroviral therapy. J Clin Endocrinol Metab (2006) 1.55

Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhoea and anorexia nervosa. Lancet (2005) 1.55

Sex disparities in the treatment and control of cardiovascular risk factors in type 2 diabetes. Diabetes Care (2008) 1.51

Circulating melanin-concentrating hormone, agouti-related protein, and alpha-melanocyte-stimulating hormone levels in relation to body composition: alterations in response to food deprivation and recombinant human leptin administration. J Clin Endocrinol Metab (2004) 1.51

Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women. Metabolism (2011) 1.51

Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies. J Clin Endocrinol Metab (2006) 1.47

Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans. Proc Natl Acad Sci U S A (2006) 1.46

Leptin in human physiology and therapeutics. Front Neuroendocrinol (2010) 1.46

Predictors of Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor-Binding Protein-3 in Critical Illness. Crit Care Med (2015) 1.38

Diabetes and risk of endometrial cancer: a population-based prospective cohort study. Cancer Epidemiol Biomarkers Prev (2007) 1.37

Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity. Diabetes (2002) 1.37

Irisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans. Eur J Endocrinol (2013) 1.37

Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: observational and interventional studies in humans. Diabetes (2002) 1.37

Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal cell lines. Metabolism (2013) 1.36

Rationale for leptin-replacement therapy for severe lipodystrophy. Endocr Pract (2010) 1.35

Leptin in humans: lessons from translational research. Am J Clin Nutr (2009) 1.35

Lipodystrophy: pathophysiology and advances in treatment. Nat Rev Endocrinol (2010) 1.34

Irisin: a renaissance in metabolism? Metabolism (2013) 1.32

Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy. J Clin Endocrinol Metab (2003) 1.32

Serum adiponectin concentrations and tissue expression of adiponectin receptors are reduced in patients with prostate cancer: a case control study. Cancer Epidemiol Biomarkers Prev (2007) 1.31

Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes. Diabetes (2006) 1.29

Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer. Clin Cancer Res (2009) 1.29

Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. Am J Physiol Endocrinol Metab (2006) 1.27

Adherence to healthy eating patterns is associated with higher circulating total and high-molecular-weight adiponectin and lower resistin concentrations in women from the Nurses' Health Study. Am J Clin Nutr (2008) 1.27

Leptin is an effective treatment for hypothalamic amenorrhea. Proc Natl Acad Sci U S A (2011) 1.26

Insulin resistance and vascular dysfunction in nondiabetic Asian Indians. J Clin Endocrinol Metab (2004) 1.26

Effect of dieting on plasma leptin, soluble leptin receptor, adiponectin and resistin levels in healthy volunteers. Clin Endocrinol (Oxf) (2004) 1.25

Energy homeostasis, obesity and eating disorders: recent advances in endocrinology. J Nutr (2004) 1.24

Human immunodeficiency virus type 1-related lipoatrophy and lipohypertrophy are associated with serum concentrations of leptin. Clin Infect Dis (2003) 1.24

Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels. Atherosclerosis (2006) 1.22

Serum adipocyte fatty acid-binding protein, retinol-binding protein 4, and adiponectin concentrations in relation to the development of the metabolic syndrome in Korean boys: a 3-y prospective cohort study. Am J Clin Nutr (2010) 1.20

Adiponectin: a link between obesity and cancer. Expert Opin Investig Drugs (2006) 1.20

Low adiponectin levels are associated with renal cell carcinoma: a case-control study. Int J Cancer (2007) 1.20

Leptin in reproduction. Curr Opin Endocrinol Diabetes Obes (2007) 1.19

Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors. Endocr Relat Cancer (2008) 1.18

Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial. Nutr J (2011) 1.16

Pancreatic cancer expresses adiponectin receptors and is associated with hypoleptinemia and hyperadiponectinemia: a case-control study. Cancer Causes Control (2008) 1.15

Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training. Eur J Endocrinol (2009) 1.14

Associations of total and high-molecular-weight adiponectin with all-cause and cardiovascular mortality in older persons: the Cardiovascular Health Study. Circulation (2012) 1.14

Effects of leptin and adiponectin on pancreatic β-cell function. Metabolism (2011) 1.13

Management of the metabolic syndrome and type 2 diabetes through lifestyle modification. Annu Rev Nutr (2009) 1.13

Leptin hormonal kinetics in the fed state: effects of adiposity, age, and gender on endogenous leptin production and clearance rates. J Clin Endocrinol Metab (2004) 1.13

Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training. Diabetes Care (2007) 1.13

Leptin and soluble leptin receptor levels in plasma and risk of type 2 diabetes in U.S. women: a prospective study. Diabetes (2009) 1.13

Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: a meta-analysis using primary data of published studies. Metabolism (2013) 1.12

Low circulating adiponectin and resistin, but not leptin, levels are associated with multiple myeloma risk: a case-control study. Cancer Causes Control (2008) 1.11

Efficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance. Diabetes (2011) 1.10

Physical activity and risk of endometrial cancer: a population-based prospective cohort study. Cancer Epidemiol Biomarkers Prev (2006) 1.10

Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. Endocr Rev (2013) 1.10

High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice. J Biol Chem (2007) 1.09

Responsiveness to peripherally administered melanocortins in lean and obese mice. Diabetes (2004) 1.08

Pharmacokinetics of subcutaneous recombinant methionyl human leptin administration in healthy subjects in the fed and fasting states: regulation by gender and adiposity. Clin Pharmacokinet (2008) 1.05

Peptide YY levels are elevated after gastric bypass surgery. Obesity (Silver Spring) (2006) 1.05

Effects of lipid-lowering drugs on irisin in human subjects in vivo and in human skeletal muscle cells ex vivo. PLoS One (2013) 1.04

Circulating irisin in healthy, young individuals: day-night rhythm, effects of food intake and exercise, and associations with gender, physical activity, diet, and body composition. J Clin Endocrinol Metab (2014) 1.04