Published in Brain Res Dev Brain Res on February 28, 2002
Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression. Environ Health Perspect (2005) 1.79
Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems. Brain Res Bull (2007) 1.72
Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood. Environ Health Perspect (2003) 1.62
Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions. Environ Health Perspect (2009) 1.56
Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure. Environ Health Perspect (2005) 1.53
Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits. Neurotoxicol Teratol (2009) 1.44
Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel. Environ Health Perspect (2007) 1.43
Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells. Environ Health Perspect (2006) 1.37
Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily. Environ Health Perspect (2007) 1.32
Neurobehavioral and neurodevelopmental effects of pesticide exposures. Neurotoxicology (2012) 1.25
Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems. Environ Health Perspect (2008) 1.22
Low dose nicotine treatment during early adolescence increases subsequent cocaine reward. Neurotoxicol Teratol (2006) 1.22
Pesticide exposure and neurodevelopmental outcomes: review of the epidemiologic and animal studies. J Toxicol Environ Health B Crit Rev (2013) 1.12
Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: effects on neurospecific proteins indicate changing vulnerabilities. Environ Health Perspect (2003) 1.12
Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro. Brain Res Bull (2008) 1.09
Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood. Brain Res Bull (2007) 1.04
Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood. Environ Health Perspect (2008) 1.00
Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells. Brain Res Bull (2008) 0.99
Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats. Brain Res Bull (2007) 0.98
Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity. Neurotoxicol Teratol (2011) 0.97
Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior. Toxicol Sci (2011) 0.97
Developmental chlorpyrifos and methyl parathion exposure alters radial-arm maze performance in juvenile and adult rats. Toxicol Sci (2009) 0.87
Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. Toxicol Sci (2011) 0.86
Long-term effects on hypothalamic neuropeptides after developmental exposure to chlorpyrifos in mice. Environ Health Perspect (2008) 0.84
Maturation of coordinated immediate early gene expression by cocaine during adolescence. Neuroscience (2009) 0.82
Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo. Brain Res Bull (2011) 0.82
Evaluation of epidemiology and animal data for risk assessment: chlorpyrifos developmental neurobehavioral outcomes. J Toxicol Environ Health B Crit Rev (2012) 0.81
Genetic aspects of behavioral neurotoxicology. Neurotoxicology (2009) 0.79
Effects of maternal chlorpyrifos diet on social investigation and brain neuroendocrine markers in the offspring - a mouse study. Environ Health (2015) 0.77
Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition. Neurotoxicology (2013) 0.77
Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor. Neurotoxicology (2015) 0.76
Monocrotophos induces the expression and activity of xenobiotic metabolizing enzymes in pre-sensitized cultured human brain cells. PLoS One (2014) 0.76
Diisopropylfluorophosphate administration in the pre-weanling period induces long-term changes in anxiety behavior and passive avoidance in adult mice. Psychopharmacology (Berl) (2005) 0.76
Strain dependent effects of conditioned fear in adult C57Bl/6 and Balb/C mice following postnatal exposure to chlorpyrifos: relation to expression of brain acetylcholinesterase mRNA. Front Behav Neurosci (2015) 0.75
Diazinon and parathion diverge in their effects on development of noradrenergic systems. Brain Res Bull (2017) 0.75
Prenatal drug exposures sensitize noradrenergic circuits to subsequent disruption by chlorpyrifos. Toxicology (2015) 0.75
Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. Toxicol Appl Pharmacol (1998) 2.58
Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. Toxicol Appl Pharmacol (1995) 2.47
Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade. Toxicol Appl Pharmacol (1997) 2.42
Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats. Brain Res Dev Brain Res (2001) 1.90
Chlorpyrifos interferes with cell development in rat brain regions. Brain Res Bull (1997) 1.88
Chlorpyrifos elicits mitotic abnormalities and apoptosis in neuroepithelium of cultured rat embryos. Teratology (1998) 1.83
Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration. Brain Res Dev Brain Res (1998) 1.60
Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity. Brain Res Dev Brain Res (2000) 1.58
Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. Environ Health Perspect (2001) 1.57
An animal model of adolescent nicotine exposure: effects on gene expression and macromolecular constituents in rat brain regions. Brain Res (2000) 1.51
Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways. Brain Res Dev Brain Res (1999) 1.48
Early biochemical detection of delayed neurotoxicity resulting from developmental exposure to chloropyrifos. Brain Res Bull (1998) 1.48
Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions. Brain Res (1999) 1.40
Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure. Brain Res (2001) 1.39
Populations of rat skeletal muscle mitochondria after exercise and immobilization. J Appl Physiol Respir Environ Exerc Physiol (1980) 1.38
Fetal and adolescent nicotine administration: effects on CNS serotonergic systems. Brain Res (2001) 1.36
Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation. Brain Res (2000) 1.34
Adrenomedullary function in the neonatal rat: responses to acute hypoxia. J Physiol (1985) 1.32
Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. Breast Cancer Res Treat (2000) 1.25
Nucleotide specificity of cardiac sarcoplasmic reticulum. GTP-induced calcium accumulation and GTPase activity. J Biol Chem (1985) 1.23
Adolescent nicotine exposure produces immediate and long-term changes in CNS noradrenergic and dopaminergic function. Brain Res (2001) 1.21
Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos? Brain Res Dev Brain Res (2000) 1.20
Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain. J Pharmacol Exp Ther (1989) 1.13
Adrenomedullary catecholamine release in the fetus and newborn: secretory mechanisms and their role in stress and survival. J Dev Physiol (1988) 1.13
Impaired cardiac function during postnatal hypoxia in rats exposed to nicotine prenatally: implications for perinatal morbidity and mortality, and for sudden infant death syndrome. Teratology (1997) 1.10
Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain. Brain Res Dev Brain Res (2002) 1.09
Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth. Brain Res Bull (1989) 1.09
Persistent and delayed behavioral changes after nicotine treatment in adolescent rats. Brain Res (2000) 1.06
Nicotine evokes cell death in embryonic rat brain during neurulation. J Pharmacol Exp Ther (1998) 1.05
Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: implications for neurotoxicity. Brain Res Dev Brain Res (2000) 1.05
Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: implications for sudden infant death syndrome. Brain Res Bull (1995) 1.05
Neuroinflammation and behavioral abnormalities after neonatal terbutaline treatment in rats: implications for autism. J Pharmacol Exp Ther (2007) 1.05
Ontogeny of adrenomedullary responses to hypoxia and hypoglycemia: role of splanchnic innervation. Brain Res Bull (1986) 1.05
Modeling adolescent nicotine exposure: effects on cholinergic systems in rat brain regions. Brain Res (2000) 1.02
Nutritional influences on adrenal chromaffin cell development: comparison with central neurons. Pediatr Res (1988) 1.02
Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studies. J Clin Invest (1994) 1.01
Calcium uptake by two preparations of mitochondria from heart. Biochim Biophys Acta (1980) 0.97
Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos. Brain Res Dev Brain Res (2001) 0.97
Mitochondrial metabolism and substrate competition in the aging Fischer rat heart. Cardiovasc Res (1993) 0.97
Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects. Biol Psychiatry (1997) 0.97
Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: differential effects on choline acetyltransferase activity and [3H]hemicholinium-3 binding. Neurotoxicol Teratol (1993) 0.95
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit. J Mol Cell Cardiol (1997) 0.95
Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase. Brain Res (2002) 0.94
Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps. J Pharmacol Exp Ther (1987) 0.93
Ontogeny of histaminergic neurotransmission in the rat brain: concomitant development of neuronal histamine, H-1 receptors, and H-1 receptor-mediated stimulation of phospholipid turnover. J Neurochem (1981) 0.93
Phospholipid asymmetry in the isolated sarcoplasmic reticulum membrane. Arch Biochem Biophys (1984) 0.92
Fetal dexamethasone exposure accelerates development of renal function: relationship to dose, cell differentiation and growth inhibition. J Dev Physiol (1992) 0.92
Prenatal exposure to nicotine via maternal infusions: effects on development of catecholamine systems. J Pharmacol Exp Ther (1988) 0.92
Poliomyelitis: hyperintensity of the anterior horn cells on MR images of the spinal cord. AJR Am J Roentgenol (1993) 0.91
Inhibition of DNA synthesis in neonatal rat brain regions caused by acute nicotine administration. Brain Res Dev Brain Res (1991) 0.90
Ontogeny of cardiac beta-adrenoceptor desensitization mechanisms: agonist treatment enhances receptor/G-protein transduction rather than eliciting uncoupling. J Mol Cell Cardiol (1999) 0.90
Modeling geriatric depression in animals: biochemical and behavioral effects of olfactory bulbectomy in young versus aged rats. J Pharmacol Exp Ther (1999) 0.89
Palmitylcarnitine inhibition of the calcium pump in cardiac sarcoplasmic reticulum: a possible role in myocardial ischemia. Life Sci (1978) 0.89
Fetal dexamethasone exposure interferes with establishment of cardiac noradrenergic innervation and sympathetic activity. Teratology (1993) 0.89
Cardiac alpha-adrenergic receptor expression is regulated by thyroid hormone during a critical developmental period. J Mol Cell Cardiol (1996) 0.89
Programming of brainstem serotonin transporter development by prenatal glucocorticoids. Brain Res Dev Brain Res (1996) 0.88
Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions. Brain Res (2000) 0.88
Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes. Brain Res Dev Brain Res (1999) 0.88
Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: implications for etiology and therapy. Proc Natl Acad Sci U S A (1990) 0.88
Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development: implications for hypoxia tolerance and perinatal mortality. Brain Res Dev Brain Res (1999) 0.88
Non-neurogenic mechanism for reserpine-induced release of catecholamines from the adrenal medulla of neonatal rats: possible modulation by opiate receptors. Neuroscience (1982) 0.87
Evidence for membrane microheterogeneity in the sarcoplasmic reticulum of fast twitch skeletal muscle. J Biol Chem (1982) 0.87
Development of central control of norepinephrine turnover and release in the rat heart: responses to tyramine, 2-deoxyglucose and hydralazine. Neuroscience (1981) 0.87
Beta-adrenoceptor signaling in the developing brain: sensitization or desensitization in response to terbutaline. Brain Res Dev Brain Res (2001) 0.86
Ontogeny of (--)-[3H]norepinephrine uptake properties of synaptic storage vesicles of rat brain. Brain Res (1978) 0.86
Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity. Biol Neonate (1992) 0.86
Nucleotide triphosphate utilization by cardiac and skeletal muscle sarcoplasmic reticulum. Evidence for a hydrolysis cycle not coupled to intermediate acyl phosphate formation and calcium translocation. J Biol Chem (1981) 0.86
Prenatal dexamethasone exposure causes loss of neonatal hypoxia tolerance: cellular mechanisms. Pediatr Res (1994) 0.86
Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period: agonists evoke supersensitivity accompanied by failure of receptor down-regulation. Pediatr Res (1996) 0.86
Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats. Brain Res (2001) 0.86
Prenatal nicotine exposure impairs beta-adrenergic function: persistent chronotropic subsensitivity despite recovery from deficits in receptor binding. Brain Res Bull (1990) 0.85
Gender differences in the behavioral manifestations of Alzheimer's disease. J Am Geriatr Soc (1996) 0.85
CaATPase content is lower in cardiac sarcoplasmic reticulum isolated from old rats. Am J Physiol (1993) 0.84
Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions. Brain Res (1990) 0.84
Non-neurogenic adrenal catecholamine release in the neonatal rat: exocytosis or diffusion? Brain Res (1986) 0.84
Cryptic brain cell injury caused by fetal nicotine exposure is associated with persistent elevations of c-fos protooncogene expression. Brain Res (1997) 0.84
Impact of fetal nicotine exposure on development of rat brain regions: critical sensitive periods or effects of withdrawal? Brain Res Bull (1993) 0.84
Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure. J Dev Physiol (1992) 0.84
Developmental regulation of the sarcoplasmic reticulum calcium pump in the rabbit heart. Pediatr Res (1992) 0.84
Anion effects on in vitro sarcoplasmic reticulum function. Co-transport of anions with calcium. J Biol Chem (1983) 0.83
Effects of maternal nicotine injections on brain development in the rat: ornithine decarboxylase activity, nucleic acids and proteins in discrete brain regions. Brain Res Bull (1986) 0.83
Histamine stimulates brain phospholipid turnover through a direct, H-1 receptor-mediated mechanism. Life Sci (1980) 0.83
Stimulation of ornithine decarboxylase by histamine or norepinephrine in brain regions of the developing rat: evidence for biogenic amines as trophic agents in neonatal brain development. Life Sci (1983) 0.83
The effect of glucagon on the kinetics of hepatic mitochondrial calcium uptake. Mol Cell Biochem (1981) 0.83
Glucocorticoid administration alters nuclear transcription factors in fetal rat brain: implications for the use of antenatal steroids. Brain Res Dev Brain Res (1998) 0.83
Altered development of basal and forskolin-stimulated adenylate cyclase activity in brain regions of rats exposed to nicotine prenatally. Brain Res Dev Brain Res (1992) 0.83
Fetal nicotine exposure alters ontogeny of M1-receptors and their link to G-proteins. Neurotoxicol Teratol (1993) 0.83
The role of dicarboxylic anion transport in the slower Ca2+ uptake in fetal cardiac sarcoplasmic reticulum. Pediatr Res (1992) 0.83
Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the pre-weanling rat. Br J Pharmacol (1979) 0.82
Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: therapeutic implications. Brain Res Bull (1998) 0.82
Exposure to methylmercury in utero: effects on biochemical development of catecholamine neurotransmitter systems. Life Sci (1984) 0.82
Rat brain synaptic vesicles: uptake specificities of [3H]norepinephrine and [3H]serotonin in preparations from whole brain and brain regions. J Neurochem (1978) 0.82
Differential development of cholinergic nerve terminal markers in rat brain regions: implications for nerve terminal density, impulse activity and specific gene expression. Brain Res (1993) 0.82
Thyroid hormone differentially regulates cellular development in neonatal rat heart and kidney. Teratology (1992) 0.82