Analysis of the prognostic significance of microscopic margins in 2,084 localized primary adult soft tissue sarcomas.

PubWeight™: 2.47‹?› | Rank: Top 2%

🔗 View Article (PMC 1422449)

Published in Ann Surg on March 01, 2002

Authors

Alexander Stojadinovic1, Denis H Y Leung, Axel Hoos, David P Jaques, Jonathan J Lewis, Murray F Brennan

Author Affiliations

1: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Articles citing this

Microscopically positive margins for primary gastrointestinal stromal tumors: analysis of risk factors and tumor recurrence. J Am Coll Surg (2012) 1.24

MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling. Cancer Res (2012) 1.24

Do surgical margin and local recurrence influence survival in soft tissue sarcomas? Clin Orthop Relat Res (2010) 1.19

Adult soft tissue sarcoma local recurrence after adjuvant treatment without resection of core needle biopsy tract. Clin Orthop Relat Res (2013) 1.17

Sporadic desmoid-type fibromatosis: a stepwise approach to a non-metastasising neoplasm--a position paper from the Italian and the French Sarcoma Group. Ann Oncol (2013) 1.16

Follow up after Primary Treatment of Soft Tissue Sarcoma: A Survey of Current Practice in the United Kingdom. Sarcoma (2007) 1.13

Validation of the prognostic relevance of plasma C-reactive protein levels in soft-tissue sarcoma patients. Br J Cancer (2013) 1.12

Multidisciplinary management of soft tissue sarcoma. ScientificWorldJournal (2013) 1.08

Clinical features, treatment, and outcome in 102 adult and pediatric patients with localized high-grade synovial sarcoma. Sarcoma (2011) 1.07

A postoperative nomogram for local recurrence risk in extremity soft tissue sarcomas after limb-sparing surgery without adjuvant radiation. Ann Surg (2012) 1.06

Prognostic significance of preoperative [18-F] fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging in patients with resectable soft tissue sarcomas. Ann Surg (2005) 1.05

Uterine leiomyosarcoma management, outcome, and associated molecular biomarkers: a single institution's experience. Ann Surg Oncol (2013) 1.02

Long-term outcome after local recurrence of soft tissue sarcoma: a retrospective analysis of factors predictive of survival in 135 patients with locally recurrent soft tissue sarcoma. Br J Cancer (2014) 1.01

Prostate embryonal rhabdomyosarcoma in adults: Case report and review of literature. Rep Pract Oncol Radiother (2013) 0.96

Why do patients with low-grade soft tissue sarcoma die? Ann Surg Oncol (2008) 0.96

Impact of unplanned excision on prognosis of patients with extremity soft tissue sarcoma. Sarcoma (2013) 0.95

Prognostic factors for local recurrence and mortality in adult soft tissue sarcoma of the extremities and trunk wall: a cohort study of 922 consecutive patients. Acta Orthop (2014) 0.93

Extremity soft tissue sarcoma resections: how wide do you need to be? Clin Orthop Relat Res (2012) 0.92

Rare chondrosarcoma of the breast treated with quadrantectomy instead of mastectomy: A case report. Oncol Lett (2014) 0.91

MRI-Based Assessment of Safe Margins in Tumor Surgery. Sarcoma (2014) 0.89

Giant liposarcoma of the posterior mediastinum and retroperitoneum. BMJ Case Rep (2011) 0.86

Reexcision of soft tissue sarcoma: sufficient local control but increased rate of metastasis. World J Surg (2009) 0.85

Localized resectable genitourinary sarcoma in adult Korean patients: experiences at a single center. Yonsei Med J (2011) 0.85

High-grade soft tissue sarcomas of the extremities: surgical margins influence only local recurrence not overall survival. Int Orthop (2015) 0.84

Managing soft tissue sarcomas in a developing country: are prognostic factors similar to those of developed world? World J Surg Oncol (2012) 0.83

Surgical management for malignant tumors of the thumb. Hand (N Y) (2011) 0.82

Non-squamous cell carcinoma of the penis: single-center, 15-year experience. World J Urol (2013) 0.82

Postoperative radiotherapy improves local control and survival in patients with uterine leiomyosarcoma. Radiat Oncol (2013) 0.80

Transarterial chemoembolization in soft-tissue sarcoma metastases to the liver - the use of imaging biomarkers as predictors of patient survival. Eur J Radiol (2014) 0.80

New drugs and combinations for the treatment of soft-tissue sarcoma: a review. Cancer Manag Res (2012) 0.80

Comparative study of planned and unplanned excisions for the treatment of soft tissue sarcoma of the extremities. Clinics (Sao Paulo) (2014) 0.79

Prognostic and survival factors in myxofibrosarcomas. Sarcoma (2012) 0.79

Prognostic factors for primary gastrointestinal stromal tumours: are they the same in the multidisciplinary treatment era? Langenbecks Arch Surg (2014) 0.79

Tumor rupture predicts early metastasis and poor prognosis in stage III soft tissue sarcomas. World J Surg (2011) 0.78

Tissue and serum IGFBP7 protein as biomarker in high-grade soft tissue sarcoma. Am J Cancer Res (2015) 0.78

The role of irradiation in the management of locally recurrent non-metastatic soft tissue sarcoma of extremity/trunkal locations. Sarcoma (2004) 0.78

[Consensus diagnosis and therapy of soft tissue sarcoma]. Wien Klin Wochenschr (2011) 0.77

GATA3 Expression Is a Poor Prognostic Factor in Soft Tissue Sarcomas. PLoS One (2016) 0.77

Reconstruction of Soft-Tissue Defects at the Foot and Ankle after Oncological Resection. Front Surg (2016) 0.76

Combining targeted agents with modern radiotherapy in soft tissue sarcomas. J Natl Cancer Inst (2014) 0.76

Soft-tissue sarcomas: are we making progress? A look at recent publications. Curr Surg (2004) 0.75

Predictors of residual disease after unplanned excision of soft tissue sarcomas. J Surg Res (2016) 0.75

Individualised risk assessment for local recurrence and distant metastases in a retrospective transatlantic cohort of 687 patients with high-grade soft tissue sarcomas of the extremities: a multistate model. BMJ Open (2017) 0.75

Clinicopathologic characteristics, treatment outcomes, and prognostic factors of primary thoracic soft tissue sarcoma: A multicenter study of the Anatolian Society of Medical Oncology (ASMO). Thorac Cancer (2015) 0.75

The Width of the Surgical Margin Does Not Influence Outcomes in Extremity and Truncal Soft Tissue Sarcoma Treated With Radiotherapy. Oncologist (2016) 0.75

Soft tissue sarcoma of the extremities: pending questions on surgery and radiotherapy. Radiat Oncol (2016) 0.75

Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells. Int J Mol Med (2016) 0.75

Case series. Soft-tissue sarcoma of the foot. Can J Surg (2010) 0.75

Recurrent pulmonary synovial sarcoma effectively treated with amrubicin: A case report. Exp Ther Med (2015) 0.75

Survival impact of centralization and clinical guidelines for soft tissue sarcoma (A prospective and exhaustive population-based cohort). PLoS One (2017) 0.75

[Retrorectal vestigial cyst : a report of a case]. Pan Afr Med J (2015) 0.75

Relative mortality in soft tissue sarcoma patients: a Danish population-based cohort study. BMC Cancer (2014) 0.75

Multimodality Management of Soft Tissue Tumors in the Extremity. Surg Clin North Am (2016) 0.75

Postoperative intensity-modulated radiation therapy provides favorable local control and low toxicities in patients with soft tissue sarcomas in the extremities and trunk wall. Onco Targets Ther (2015) 0.75

Impact of residual disease after "unplanned excision" of primary localized adult soft tissue sarcoma of the extremities: evaluation of 452 cases at a single Institution. Musculoskelet Surg (2017) 0.75

Nonrhabdomyosarcoma soft tissue sarcoma (NRSTS) in pediatric and young adult patients: Results from a prospective study using limited-margin radiotherapy. Cancer (2017) 0.75

Somatic Leiomyosarcoma of the Soft Tissues: A Single-Institutional Analysis of Factors Predictive of Survival in 164 Patients. World J Surg (2017) 0.75

Head and neck sarcoma: report of a case treated by intensity-modulated radiation therapy. Int J Clin Oncol (2010) 0.75

Phase 1 trial of preoperative image guided intensity modulated proton radiation therapy with simultaneously integrated boost to the high risk margin for retroperitoneal sarcomas. Adv Radiat Oncol (2017) 0.75

Articles cited by this

Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg (1998) 5.87

Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J Clin Oncol (1998) 5.74

Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities. J Clin Oncol (1996) 5.40

Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma. J Clin Oncol (1996) 3.85

Prognostic factors predictive of survival for truncal and retroperitoneal soft-tissue sarcoma. Ann Surg (1995) 2.28

Management of primary and recurrent soft-tissue sarcoma of the retroperitoneum. Ann Surg (1990) 2.17

The continuing challenge of retroperitoneal sarcomas. Cancer (1981) 1.95

Extra-abdominal desmoid tumors. J Bone Joint Surg Am (1984) 1.89

Effect of reresection in extremity soft tissue sarcoma. Ann Surg (2000) 1.80

The role of the pathologist in the management of soft tissue sarcomas. World J Surg (1988) 1.64

Multifactorial analysis of long-term follow-up (more than 5 years) of primary extremity sarcoma. Arch Surg (1999) 1.54

Preoperative radiation, surgical margins, and local control of extremity sarcomas of soft tissues. J Surg Oncol (1993) 1.51

Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas. Cancer (1994) 1.32

The local management of soft tissue sarcoma. Semin Radiat Oncol (1999) 1.17

Articles by these authors

Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med (2010) 67.34

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med (2011) 26.90

Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res (2009) 24.11

Delivering affordable cancer care in high-income countries. Lancet Oncol (2011) 12.79

Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. Lancet (2009) 8.69

Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol (2009) 8.68

Clinicopathologic correlates of solitary fibrous tumors. Cancer (2002) 5.96

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clin Cancer Res (2005) 5.44

Actual 10-year survival after resection of colorectal liver metastases defines cure. J Clin Oncol (2007) 4.95

Merkel cell carcinoma: prognosis and treatment of patients from a single institution. J Clin Oncol (2005) 4.79

Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg (2003) 4.25

Quality of complication reporting in the surgical literature. Ann Surg (2002) 4.21

An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial. Lancet (2008) 4.11

Solid-pseudopapillary tumor of the pancreas: a surgical enigma? Ann Surg Oncol (2002) 3.96

Pasireotide for postoperative pancreatic fistula. N Engl J Med (2014) 3.84

Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group. J Clin Oncol (2008) 3.82

Postoperative nomogram for 12-year sarcoma-specific death. J Clin Oncol (2002) 3.60

Postoperative nomogram for disease-specific survival after an R0 resection for gastric carcinoma. J Clin Oncol (2003) 3.56

A selective approach to the resection of cystic lesions of the pancreas: results from 539 consecutive patients. Ann Surg (2006) 3.34

Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis. Lancet Oncol (2009) 3.26

Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. Ann Surg (2006) 3.23

Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI). Cancer Immunol Immunother (2007) 3.16

Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST). Cancer (2008) 3.10

Comparison of gastric cancer survival following R0 resection in the United States and Korea using an internationally validated nomogram. Ann Surg (2010) 2.99

Electronic synoptic operative reporting: assessing the reliability and completeness of synoptic reports for pancreatic resection. J Am Coll Surg (2010) 2.98

"MIATA"-minimal information about T cell assays. Immunity (2009) 2.90

Patterns of initial recurrence in completely resected gastric adenocarcinoma. Ann Surg (2004) 2.86

A 14-year retrospective review of angiosarcoma: clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy. Cancer J (2005) 2.71

p63 expression profiles in human normal and tumor tissues. Clin Cancer Res (2002) 2.68

Intraductal papillary mucinous neoplasms of the pancreas: an analysis of clinicopathologic features and outcome. Ann Surg (2004) 2.62

Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings. J Clin Oncol (2002) 2.57

Surgical treatment and outcomes of patients with primary inferior vena cava leiomyosarcoma. J Am Coll Surg (2003) 2.54

Adult spermatic cord sarcomas: management and results. Ann Surg Oncol (2003) 2.52

Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients. Cancer Res (2002) 2.41

Prognostic factors in pancreatic endocrine neoplasms: an analysis of 136 cases with a proposal for low-grade and intermediate-grade groups. J Clin Oncol (2002) 2.39

Long-term survival is superior after resection for cancer in high-volume centers. Ann Surg (2005) 2.38

Results of tyrosine kinase inhibitor therapy followed by surgical resection for metastatic gastrointestinal stromal tumor. Ann Surg (2007) 2.37

The influence of hospital and surgeon volume on in-hospital mortality for colectomy, gastrectomy, and lung lobectomy in patients with cancer. Surgery (2002) 2.32

Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors. Clin Cancer Res (2003) 2.32

Defining the critical hurdles in cancer immunotherapy. J Transl Med (2011) 2.32

Adult genitourinary sarcoma: the 25-year Memorial Sloan-Kettering experience. J Urol (2006) 2.30

Operative drainage following pancreatic resection: analysis of 1122 patients resected over 5 years at a single institution. Ann Surg (2013) 2.29

The value of splenic preservation with distal pancreatectomy. Arch Surg (2002) 2.27

American Surgical Association Blue Ribbon Committee Report on Surgical Education: 2004. Ann Surg (2005) 2.25

Laparoscopic versus open distal gastrectomy for gastric cancer: a meta-analysis of randomized controlled trials and high-quality nonrandomized studies. Ann Surg (2012) 2.23

Pancreatic adenocarcinoma: the actual 5-year survivors. J Gastrointest Surg (2007) 2.22

Long-term survival following treatment of pseudomyxoma peritonei: an analysis of surgical therapy. Ann Surg (2005) 2.19

Classification of clear-cell sarcoma as a subtype of melanoma by genomic profiling. J Clin Oncol (2003) 2.18

Results after pancreatic resection for metastatic lesions. Ann Surg Oncol (2002) 2.15

Clinically aggressive solid pseudopapillary tumors of the pancreas: a report of two cases with components of undifferentiated carcinoma and a comparative clinicopathologic analysis of 34 conventional cases. Am J Surg Pathol (2005) 2.12

Defining morbidity after pancreaticoduodenectomy: use of a prospective complication grading system. J Am Coll Surg (2007) 2.12

Laparoscopic versus open subtotal gastrectomy for adenocarcinoma: a case-control study. Ann Surg Oncol (2009) 2.10

Atypical lipomatous tumor/well-differentiated liposarcoma of the extremity and trunk wall: importance of histological subtype with treatment recommendations. Ann Surg Oncol (2004) 2.09

Prospective functional voice assessment in patients undergoing thyroid surgery. Ann Surg (2002) 2.08

Ipilimumab efficacy and safety in patients with advanced melanoma: a retrospective analysis of HLA subtype from four trials. Cancer Immun (2010) 2.07

Conventional hemangiopericytoma: modern analysis of outcome. Cancer (2002) 2.04

Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma. Ann N Y Acad Sci (2013) 2.03

Survival after hepatic resection for metastatic colorectal cancer: trends in outcomes for 1,600 patients during two decades at a single institution. J Am Coll Surg (2010) 1.98

The impact of complications on outcomes after resection for esophageal and gastroesophageal junction carcinoma. J Am Coll Surg (2004) 1.97

Classification and subtype prediction of adult soft tissue sarcoma by functional genomics. Am J Pathol (2003) 1.94

Localized extremity soft tissue sarcoma: improved knowledge with unchanged survival over time. J Clin Oncol (2003) 1.92

Primary adult soft tissue sarcoma: time-dependent influence of prognostic variables. J Clin Oncol (2002) 1.89

The New American Joint Committee on Cancer/International Union Against Cancer staging system for adenocarcinoma of the stomach: increased complexity without clear improvement in predictive accuracy. Ann Surg Oncol (2012) 1.87

Prognostic significance of pathologic nodal status in patients with resected pancreatic cancer. J Gastrointest Surg (2007) 1.86

Positive peritoneal cytology in patients with gastric cancer: natural history and outcome of 291 patients. Ann Surg Oncol (2010) 1.85

Harmonization of immune biomarker assays for clinical studies. Sci Transl Med (2011) 1.84

Does graded histologic response after neoadjuvant chemotherapy predict survival for completely resected gastric cancer? Ann Surg Oncol (2007) 1.84

Adenocarcinoma of the duodenum: importance of accurate lymph node staging and similarity in outcome to gastric cancer. Ann Surg Oncol (2004) 1.82

Intraductal papillary-mucinous neoplasms of the pancreas: an analysis of in situ and invasive carcinomas in 28 patients. Cancer (2002) 1.82

Soft tissue sarcomas of adults: state of the translational science. Clin Cancer Res (2003) 1.81

A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen. J Immunol (2003) 1.81

Low-grade myxofibrosarcoma: a clinicopathologic analysis of 49 cases treated at a single institution with simultaneous assessment of the efficacy of 3-tier and 4-tier grading systems. Hum Pathol (2004) 1.80

Defining palliative surgery in patients receiving noncurative resections for gastric cancer. J Am Coll Surg (2004) 1.80

Chemotherapy is associated with improved survival in adult patients with primary extremity synovial sarcoma. Ann Surg (2007) 1.75

Survival after resection of pancreatic adenocarcinoma: results from a single institution over three decades. Ann Surg Oncol (2011) 1.75

Prognostic indicators of outcomes in patients with distant metastases from differentiated thyroid carcinoma. J Am Coll Surg (2003) 1.74

Multiple primary soft tissue sarcomas. Cancer (2004) 1.73

Laparoscopic adrenalectomy for isolated adrenal metastasis. Ann Surg Oncol (2007) 1.71

Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? J Clin Oncol (2010) 1.70

CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS. Nat Clin Pract Oncol (2008) 1.70

KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors. Cancer Res (2009) 1.69

Management of primary liver sarcomas. Cancer (2007) 1.65

Clinical outcomes of systemic therapy for patients with deep fibromatosis (desmoid tumor). Cancer (2010) 1.64

A synovial sarcoma-specific preoperative nomogram supports a survival benefit to ifosfamide-based chemotherapy and improves risk stratification for patients. Clin Cancer Res (2008) 1.64

Determining prognosis in patients with pancreatic endocrine neoplasms: can the WHO classification system be simplified? J Clin Oncol (2007) 1.64

Harmonization guidelines for HLA-peptide multimer assays derived from results of a large scale international proficiency panel of the Cancer Vaccine Consortium. Cancer Immunol Immunother (2009) 1.63