Published in Biophys J on May 01, 2002
The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. Mol Biol Cell (2004) 1.30
Softness, strength and self-repair in intermediate filament networks. Exp Cell Res (2007) 1.29
A self-consistent field analysis of the neurofilament brush with amino-acid resolution. Biophys J (2007) 1.07
Balls and chains--a mesoscopic approach to tethered protein domains. Biophys J (2006) 0.99
Elasticity in ionically cross-linked neurofilament networks. Biophys J (2010) 0.98
Intrinsically disordered proteins drive membrane curvature. Nat Commun (2015) 0.96
Mechanical and structural properties of in vitro neurofilament hydrogels. Eur Biophys J (2007) 0.90
Gel-expanded to gel-condensed transition in neurofilament networks revealed by direct force measurements. Nat Mater (2009) 0.89
Physical model for the width distribution of axons. Eur Phys J E Soft Matter (2009) 0.86
Effect of the ionic strength and pH on the equilibrium structure of a neurofilament brush. Biophys J (2007) 0.86
Hamiltonian Switch Metropolis Monte Carlo Simulations for Improved Conformational Sampling of Intrinsically Disordered Regions Tethered to Ordered Domains of Proteins. J Chem Theory Comput (2014) 0.85
Interplay between liquid crystalline and isotropic gels in self-assembled neurofilament networks. Biophys J (2008) 0.85
How the projection domains of NF-L and alpha-internexin determine the conformations of NF-M and NF-H in neurofilaments. Eur Biophys J (2010) 0.81
A critical reevaluation of the stationary axonal cytoskeleton hypothesis. Cytoskeleton (Hoboken) (2012) 0.79
The polymer brush model of neurofilament projections: effect of protein composition. Biophys J (2010) 0.78
A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases. PLoS Comput Biol (2015) 0.75
Site-Specific Modulation of Charge Controls the Structure and Stimulus Responsiveness of Intrinsically Disordered Peptide Brushes. Langmuir (2016) 0.75
Prediction of protein secondary structure at better than 70% accuracy. J Mol Biol (1993) 17.53
Analysis of compositionally biased regions in sequence databases. Methods Enzymol (1996) 17.11
The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol (2000) 10.20
Combining evolutionary information and neural networks to predict protein secondary structure. Proteins (1994) 9.97
Why are "natively unfolded" proteins unstructured under physiologic conditions? Proteins (2000) 7.61
Sequence complexity of disordered protein. Proteins (2001) 6.97
An information theory model of hydrophobic interactions. Proc Natl Acad Sci U S A (1996) 3.40
Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell (1992) 2.80
Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons. J Neurosci (1998) 2.43
The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. EMBO J (1988) 2.21
Antibody decoration of neurofilaments. J Cell Biol (1981) 2.12
An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments. Cell (1996) 2.09
Self-assembly in Vitro of the 68,000 molecular weight component of the mammalian neurofilament triplet proteins into intermediate-sized filaments. J Mol Biol (1981) 2.09
Identification of the major multiphosphorylation site in mammalian neurofilaments. Proc Natl Acad Sci U S A (1988) 1.87
Thousands of proteins likely to have long disordered regions. Pac Symp Biocomput (1998) 1.79
Neuronal intermediate filaments. Annu Rev Neurosci (1996) 1.78
The pathobiology of traumatically induced axonal injury in animals and humans: a review of current thoughts. J Neurotrauma (1995) 1.69
Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber. J Cell Biol (1994) 1.67
Entropic exclusion by neurofilament sidearms: a mechanism for maintaining interfilament spacing. Biochemistry (1997) 1.57
Pair distribution functions of bacteriorhodopsin and rhodopsin in model bilayers. Biophys J (1983) 1.54
Arp2/3 complex from Acanthamoeba binds profilin and cross-links actin filaments. Mol Biol Cell (1998) 1.52
High tolerance and delayed elastic response of cultured axons to dynamic stretch injury. J Neurosci (1999) 1.50
The 'ins' and 'outs' of intermediate filament organization. Trends Cell Biol (2000) 1.46
A molecular mechanism for the induction of neurofilament bundling by aluminum ions. J Neurochem (1992) 1.42
Structure of the peripheral domains of neurofilaments revealed by low angle rotary shadowing. J Mol Biol (1988) 1.39
Neurofilament functions in health and disease. Curr Opin Neurobiol (1999) 1.27
How a gap junction maintains its structure. Nature (1984) 1.26
The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons. J Cell Biol (1999) 1.23
The proteolytic digestion of ox neurofilaments with trypsin and alpha-chymotrypsin. Biochem J (1983) 1.17
An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res Brain Res Rev (1999) 1.17
Functional protein domains from the thermally driven motion of polypeptide chains: a proposal. Proteins (1998) 1.13
AFM force measurements on microtubule-associated proteins: the projection domain exerts a long-range repulsive force. FEBS Lett (2001) 1.12
Lateral interactions among membrane proteins. Valid estimates based on freeze-fracture electron microscopy. Biophys J (1987) 1.09
Properties of highly viscous gels formed by neurofilaments in vitro. A possible consequence of a specific inter-filament cross-bridging. Biochem J (1987) 1.06
The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation. J Cell Sci (2000) 1.00
Phosphorylation state of the native high-molecular-weight neurofilament subunit protein from cervical spinal cord in sporadic amyotrophic lateral sclerosis. J Neurochem (2001) 0.98
Spatial distribution of surface immunoglobulin on B lymphocytes. Local ordering. Exp Cell Res (1978) 0.98
Influence of the phosphorylation state of neurofilament proteins on the interactions between purified filaments in vitro. Biochem J (1988) 0.95
Chemical modification of charged amino acid moieties alters the electrophoretic mobilities of neurofilament subunits on SDS/polyacrylamide gels. Eur J Biochem (1987) 0.94
Regulation of neurofilament interactions in vitro by natural and synthetic polypeptides sharing Lys-Ser-Pro sequences with the heavy neurofilament subunit NF-H: neurofilament crossbridging by antiparallel sidearm overlapping. Med Biol Eng Comput (1998) 0.91
Phosphorylation and subunit organization of axonal neurofilaments determined by scanning transmission electron microscopy. Proc Natl Acad Sci U S A (1997) 0.90
Neurofilament distribution and organization in the myelinated axons of the peripheral nervous system. Brain Res (1994) 0.89
Dephosphorylation of the largest neurofilament subunit protein influences the structure of crossbridges in reassembled neurofilaments. J Cell Sci (1994) 0.83
Early cytoskeletal changes following injury of giant spinal axons in the lamprey. J Comp Neurol (1995) 0.80
Avoidance model for soft particles. II. Positional ordering of charged rods. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics (2000) 0.78
Characterization of the phosphorylation sites of the squid (Loligo pealei) high-molecular-weight neurofilament protein from giant axon axoplasm. J Neurochem (2001) 0.77
Characterization of two proteolytically derived soluble polypeptides from the neurofilament triplet components NFM and NFH. Biochem J (1989) 0.77
Bace1 modulates myelination in the central and peripheral nervous system. Nat Neurosci (2006) 3.85
Axon-glial signaling and the glial support of axon function. Annu Rev Neurosci (2008) 3.82
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med (2002) 3.68
Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients. Ann Neurol (2006) 2.93
Subpial demyelination in the cerebral cortex of multiple sclerosis patients. J Neuropathol Exp Neurol (2003) 2.85
Constitutively active Akt induces enhanced myelination in the CNS. J Neurosci (2008) 2.60
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology (2007) 2.10
Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients. Ann Neurol (2011) 1.98
Depolarization-induced Ca2+ release in ischemic spinal cord white matter involves L-type Ca2+ channel activation of ryanodine receptors. Neuron (2003) 1.95
Macrophage microvesicles induce macrophage differentiation and miR-223 transfer. Blood (2012) 1.80
Imaging correlates of decreased axonal Na+/K+ ATPase in chronic multiple sclerosis lesions. Ann Neurol (2008) 1.80
Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis. J Neuropathol Exp Neurol (2002) 1.70
Evidence for synaptic stripping by cortical microglia. Glia (2007) 1.63
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis. Brain (2011) 1.63
The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nat Neurosci (2009) 1.60
Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves. FASEB J (2008) 1.60
Role of fluctuations in a snug-fit mechanism of KcsA channel selectivity. J Chem Phys (2006) 1.59
Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis. Prog Neurobiol (2010) 1.54
Lymphocyte cytosolic protein 1 is a chronic lymphocytic leukemia membrane-associated antigen critical to niche homing. Blood (2013) 1.50
Micromechanical architecture of the endothelial cell cortex. Biophys J (2004) 1.47
Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4. J Neurosci (2012) 1.46
Insights into the molecular mechanism of membrane fusion from simulation: evidence for the association of splayed tails. Phys Rev Lett (2003) 1.40
Growth of beta-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy. Biochemistry (2002) 1.35
Imaging correlates of axonal swelling in chronic multiple sclerosis brains. Ann Neurol (2007) 1.31
Evolution of a neuroprotective function of central nervous system myelin. J Cell Biol (2006) 1.25
Cleavage of neuregulin-1 by BACE1 or ADAM10 protein produces differential effects on myelination. J Biol Chem (2011) 1.25
Reduced amino acid alphabet is sufficient to accurately recognize intrinsically disordered protein. FEBS Lett (2004) 1.25
Myelination and axonal electrical activity modulate the distribution and motility of mitochondria at CNS nodes of Ranvier. J Neurosci (2011) 1.23
Molecular mechanisms for organizing the neuronal cytoskeleton. Bioessays (2004) 1.23
NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells. Glia (2007) 1.21
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. EMBO J (2007) 1.19
N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve. Ann Neurol (2002) 1.17
Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells. Nat Neurosci (2013) 1.16
Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells. Hepatology (2014) 1.16
Structure and stability of internodal myelin in mouse models of hereditary neuropathy. J Neuropathol Exp Neurol (2005) 1.16
Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox Res (2003) 1.14
Glutamate receptors on myelinated spinal cord axons: II. AMPA and GluR5 receptors. Ann Neurol (2009) 1.14
Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors. Ann Neurol (2009) 1.12
Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors. Ann Neurol (2013) 1.11
Hydration structure and free energy of biomolecularly specific aqueous dications, including Zn2+ and first transition row metals. J Am Chem Soc (2004) 1.10
Neurogenesis in the chronic lesions of multiple sclerosis. Brain (2008) 1.10
Demyelination increases axonal stationary mitochondrial size and the speed of axonal mitochondrial transport. J Neurosci (2010) 1.10
The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease. Neuromolecular Med (2004) 1.10
Modulation of repulsive forces between neurofilaments by sidearm phosphorylation. Biochem Biophys Res Commun (2004) 1.09
Imaging correlates of leukocyte accumulation and CXCR4/CXCL12 in multiple sclerosis. Arch Neurol (2009) 1.07
The tetraspanin protein, CD9, is expressed by progenitor cells committed to oligodendrogenesis and is linked to beta1 integrin, CD81, and Tspan-2. Glia (2002) 1.07
Clinically feasible MTR is sensitive to cortical demyelination in MS. Neurology (2012) 1.07
Evidence for a highly elastic shell-core organization of cochlear outer hair cells by local membrane indentation. Biophys J (2005) 1.05
Neuropathobiology of multiple sclerosis. Neurol Clin (2005) 1.04
Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology. J Biol Chem (2004) 1.03
Microelastic properties of lung cell-derived extracellular matrix. Acta Biomater (2010) 1.02
Detection of antigen-specific T cells on p/MHC microarrays. J Mol Recognit (2007) 1.01
Cortical remyelination: a new target for repair therapies in multiple sclerosis. Ann Neurol (2012) 1.00
Preconditioning paradigms and pathways in the brain. Cleve Clin J Med (2008) 0.99
Sodium channel expression within chronic multiple sclerosis plaques. J Neuropathol Exp Neurol (2007) 0.99
Expression of protein 4.1G in Schwann cells of the peripheral nervous system. J Neurosci Res (2006) 0.98
Gray-matter injury in multiple sclerosis. N Engl J Med (2009) 0.97
Treatment of experimental autoimmune encephalomyelitis with the chemokine receptor antagonist Met-RANTES. J Neuroimmunol (2002) 0.97
Activation of the ciliary neurotrophic factor (CNTF) signalling pathway in cortical neurons of multiple sclerosis patients. Brain (2007) 0.96
VCAM-1-positive microglia target oligodendrocytes at the border of multiple sclerosis lesions. J Neuropathol Exp Neurol (2002) 0.96
Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. J Neuroimmunol (2006) 0.96
Human myelin proteome and comparative analysis with mouse myelin. Proc Natl Acad Sci U S A (2009) 0.95
NG2-positive glia in the human central nervous system. Neuron Glia Biol (2009) 0.94
Dysmyelinated lower motor neurons retract and regenerate dysfunctional synaptic terminals. J Neurosci (2004) 0.93
Insights into protein structure and function from disorder-complexity space. Proteins (2007) 0.93
Relapsing and progressive forms of multiple sclerosis: insights from pathology. Curr Opin Neurol (2014) 0.92
Beta IV tubulin is selectively expressed by oligodendrocytes in the central nervous system. Glia (2005) 0.89
Pressure denaturation of staphylococcal nuclease studied by neutron small-angle scattering and molecular simulation. Biophys J (2004) 0.89
Characterization of multiple myeloma vesicles by label-free relative quantitation. Proteomics (2013) 0.89
High fidelity functional patterns of an extracellular matrix protein by electron beam-based inactivation. J Am Chem Soc (2007) 0.88
Activated microglia enhance neurogenesis via trypsinogen secretion. Proc Natl Acad Sci U S A (2013) 0.88
Biology of Schwann cells. Handb Clin Neurol (2013) 0.87
Rapid assembly of amyloid-beta peptide at a liquid/liquid interface produces unstable beta-sheet fibers. Biochemistry (2005) 0.86
Deblurred observation of the molecular structure of an oil-water interface. J Am Chem Soc (2005) 0.86
Modes of remodeling in the cortical cytoskeleton of vascular endothelial cells. FEBS Lett (2005) 0.85
Directed immobilization of protein-coated nanospheres to nanometer-scale patterns fabricated by electron beam lithography of poly(ethylene glycol) self-assembled monolayers. Langmuir (2006) 0.85
Role of long-range repulsive forces in organizing axonal neurofilament distributions: evidence from mice deficient in myelin-associated glycoprotein. J Neurosci Res (2002) 0.85
Taking two TRAILS. Neuron (2005) 0.85
Pathogenesis of multiple sclerosis: the eyes only see what the mind is prepared to comprehend. Ann Neurol (2004) 0.85
The 36K protein of zebrafish CNS myelin is a short-chain dehydrogenase. Glia (2004) 0.84
Targeted drug delivery and cross-linking induced apoptosis with anti-CD37 based dual-ligand immunoliposomes in B chronic lymphocytic leukemia cells. Biomaterials (2013) 0.83
Coordination state probabilities and the solvation free energy of Zn2+ in aqueous methanol solutions. J Chem Phys (2012) 0.83
Amyloid-beta aggregates formed at polar-nonpolar interfaces differ from amyloid-beta protofibrils produced in aqueous buffers. Microsc Res Tech (2005) 0.83
Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis. Acta Neuropathol (2012) 0.83