Published in Clin Chem Lab Med on March 01, 2002
mTOR Inhibitors in Tuberous Sclerosis Complex. Curr Neuropharmacol (2012) 1.09
Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin. Cancer Chemother Pharmacol (2007) 1.02
A rapid HPLC-MS/MS method for the simultaneous quantification of cyclosporine A, tacrolimus, sirolimus and everolimus in human blood samples. Nat Protoc (2009) 0.92
Simultaneous determination of cyclosporine A, tacrolimus, sirolimus, and everolimus in whole-blood samples by LC-MS/MS. ScientificWorldJournal (2012) 0.83
Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats. Dig Dis Sci (2004) 0.83
Therapeutic drug monitoring in pediatric renal transplantation. Pediatr Nephrol (2014) 0.78
Pharmacokinetics of orally administered low-dose rapamycin in healthy dogs. Am J Vet Res (2016) 0.77
Comparison between ultra-performance liquid chromatography with tandem mass spectrometry and a chemiluminescence immunoassay in the determination of cyclosporin A and tacrolimus levels in whole blood. Exp Ther Med (2013) 0.77
Second messenger-mediated adjustment of bacterial swimming velocity. Cell (2010) 3.69
c-di-AMP is a new second messenger in Staphylococcus aureus with a role in controlling cell size and envelope stress. PLoS Pathog (2011) 2.55
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J Biol Chem (2004) 2.29
Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks. Mol Cell (2011) 1.64
Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR. Mol Cell Biol (2004) 1.52
Cyclic di-AMP homeostasis in bacillus subtilis: both lack and high level accumulation of the nucleotide are detrimental for cell growth. J Biol Chem (2012) 1.49
Pharmacokinetics of ampicillin/sulbactam in critically ill patients with acute kidney injury undergoing extended dialysis. Clin J Am Soc Nephrol (2012) 1.48
Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom (2005) 1.44
A liquid chromatography-coupled tandem mass spectrometry method for quantitation of cyclic di-guanosine monophosphate. J Microbiol Methods (2010) 1.40
YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa. PLoS Pathog (2010) 1.40
Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes. J Biol Chem (2003) 1.35
MEK1-dependent delayed expression of Fos-related antigen-1 counteracts c-Fos and p65 NF-kappaB-mediated interleukin-8 transcription in response to cytokines or growth factors. J Biol Chem (2004) 1.29
Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization. Biochem Biophys Res Commun (2003) 1.29
c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol Cell Biol (2008) 1.20
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein. Neuropharmacology (2006) 1.18
Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle. PLoS Genet (2013) 1.12
Evidence for general stabilization of mRNAs in response to UV light. Eur J Biochem (2002) 1.11
The Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathway. EMBO Rep (2006) 1.10
Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA. Biochemistry (2010) 1.09
Tigecycline possibly underdosed for the treatment of pneumonia: a pharmacokinetic viewpoint. Int J Antimicrob Agents (2009) 1.08
Nucleotidyl cyclase activity of soluble guanylyl cyclase α1β1. Biochemistry (2011) 1.05
Pharmacokinetics of ertapenem in critically ill patients with acute renal failure undergoing extended daily dialysis. Nephrol Dial Transplant (2008) 1.03
The death domain of IRAK-1: an oligomerization domain mediating interactions with MyD88, Tollip, IRAK-1, and IRAK-4. Biochem Biophys Res Commun (2007) 0.98
Human cyclic nucleotide phosphodiesterases possess a much broader substrate-specificity than previously appreciated. FEBS Lett (2011) 0.95
Type IV pilus assembly in Pseudomonas aeruginosa over a broad range of cyclic di-GMP concentrations. J Bacteriol (2012) 0.94
The Gac/Rsm and cyclic-di-GMP signalling networks coordinately regulate iron uptake in Pseudomonas aeruginosa. Environ Microbiol (2013) 0.94
Inhibition of mRNA deadenylation and degradation by ultraviolet light. Biol Chem (2005) 0.94
CD4+ T cells recognizing specific antigen deposited in glomeruli cause glomerulonephritis-like kidney injury. Clin Immunol (2002) 0.93
Quantification of cyclic dinucleotides by reversed-phase LC-MS/MS. Methods Mol Biol (2013) 0.92
Rapid HPLC-MS/MS method for simultaneous quantitation of four routinely administered triazole antifungals in human plasma. Clin Chim Acta (2011) 0.89
Simultaneous determination of four immunosuppressants by means of high speed and robust on-line solid phase extraction-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.88
Peptide-mediated disruption of NFkappaB/NRF interaction inhibits IL-8 gene activation by IL-1 or Helicobacter pylori. J Immunol (2007) 0.88
Identification of the alternative sigma factor SigX regulon and its implications for Pseudomonas aeruginosa pathogenicity. J Bacteriol (2013) 0.88
Epidemiology and survival of patients with hepatocellular carcinoma in Southern Germany. Int J Clin Exp Med (2010) 0.86
The YmdB phosphodiesterase is a global regulator of late adaptive responses in Bacillus subtilis. J Bacteriol (2013) 0.85
Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities. Pharm Res (2008) 0.85
cCMP is a substrate for MRP5. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.85
UV radiation induces CXCL5 expression in human skin. Exp Dermatol (2015) 0.84
Postoperative intravenous infusion of donor-derived transplant acceptance-inducing cells as an adjunct immunosuppressive therapy in a porcine pulmonary allograft model. Transpl Int (2008) 0.84
Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats. Dig Dis Sci (2004) 0.83
Production of prostaglandin E2 in monocytes stimulated in vitro by Chlamydia trachomatis, Chlamydophila pneumoniae, and Mycoplasma fermentans. Microb Pathog (2004) 0.83
Quantification of the carbapenem antibiotic ertapenem in human plasma by a validated liquid chromatography-mass spectrometry method. Clin Chim Acta (2005) 0.83
Risk of underdosing of ampicillin/sulbactam in patients with acute kidney injury undergoing extended daily dialysis--a single case. Nephrol Dial Transplant (2009) 0.82
Binding of regulatory subunits of cyclic AMP-dependent protein kinase to cyclic CMP agarose. PLoS One (2012) 0.82
NF-kappaB-repressing factor inhibits elongation of human immunodeficiency virus type 1 transcription by DRB sensitivity-inducing factor. Mol Cell Biol (2005) 0.81
JKTBP1 is involved in stabilization and IRES-dependent translation of NRF mRNAs by binding to 5' and 3' untranslated regions. J Mol Biol (2011) 0.81
Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcription. J Clin Immunol (2010) 0.81
Threonine 66 in the death domain of IRAK-1 is critical for interaction with signaling molecules but is not a target site for autophosphorylation. J Leukoc Biol (2008) 0.81
Liver transplantation for sclerosing cholangitis in a polytraumatized patient. Nat Clin Pract Gastroenterol Hepatol (2008) 0.81
Correlation of donor leukocyte chimerism with pulmonary allograft survival after immunosuppressive drug withdrawal in a porcine model. Transplantation (2009) 0.80
Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.80
Maternal effects and cancer risk in the progeny of mice exposed to X-rays before conception. Exp Toxicol Pathol (2005) 0.80
Small interfering RNAs generated by recombinant dicer induce inflammatory gene expression independent from the TAK1-NFkappaB-MAPK signaling pathways. Biochem Biophys Res Commun (2006) 0.80
NRF IRES activity is mediated by RNA binding protein JKTBP1 and a 14-nt RNA element. RNA (2007) 0.80
Cyclosporine-induced gingival overgrowth correlates with NFAT-regulated gene expression: a pilot study. J Clin Periodontol (2011) 0.79
Improved outcome after 'bottom-up' immunosuppression in liver transplant recipients with preoperative renal impairment. Eur Surg Res (2010) 0.79
Effects of curcumin on cyclosporine-induced cholestasis and hypercholesterolemia and on cyclosporine metabolism in the rat. Planta Med (2003) 0.78
The Receptor-Bound Guanylyl Cyclase DAF-11 Is the Mediator of Hydrogen Peroxide-Induced cGMP Increase in Caenorhabditis elegans [corrected].. PLoS One (2013) 0.78
Dual input control: activation of the Bartonella henselae VirB/D4 type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two-component system. Mol Microbiol (2013) 0.78
Protein kinase Cbeta1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion. Int Immunol (2003) 0.78
Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2',(3')-substituted purine and pyrimidine nucleotides. J Pharmacol Exp Ther (2010) 0.78
Direct and fast determination of antiretroviral drugs by automated online solid-phase extraction-liquid chromatography-tandem mass spectrometry in human plasma. Clin Chem Lab Med (2006) 0.78
Systematic analysis of histamine and N-methylhistamine concentrations in organs from two common laboratory mouse strains: C57Bl/6 and Balb/c. Inflamm Res (2011) 0.78
Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model. Br J Pharmacol (2002) 0.77
High caspofungin levels in alveolar cells of a lung transplant patient with suspected pulmonary aspergillosis. Int J Antimicrob Agents (2009) 0.77
Influence of cyclosporine on the serum concentration and biliary excretion of mycophenolic acid and 7-O-mycophenolic acid glucuronide. Ther Drug Monit (2005) 0.77
Genomic analysis of cyclic-di-GMP-related genes in rhizobial type strains and functional analysis in Rhizobium etli. Appl Microbiol Biotechnol (2014) 0.77
A systematic approach for the solubilization of the integral membrane protein lysophospholipid: Acyl-Coa acyltransferase (LAT). Methods Mol Biol (2003) 0.76
Injection of IL-12- and IL-18-encoding plasmids ameliorates the autoimmune pathology of MRL/Mp-Tnfrsf6lpr mice: synergistic effect on autoimmune symptoms. Int Immunol (2006) 0.76
Leukemias induced by altered TRK-signaling are sensitive to mTOR inhibitors in preclinical models. Ann Hematol (2010) 0.76
Structure/activity relationships of (M)ANT- and TNP-nucleotides for inhibition of rat soluble guanylyl cyclase α1β1. Mol Pharmacol (2014) 0.76
[Endosonographic anatomy of the ventricular system]. Ideggyogy Sz (2002) 0.75
Esophageal tissue injury following pulmonary vein isolation using the PVAC: assessment by endoscopy and magnetic resonance imaging. Pacing Clin Electrophysiol (2013) 0.75
Quantitative analysis of the antifungal drug anidulafungin by LC-online SPE-MS/MS in human plasma. Biomed Chromatogr (2011) 0.75
Colonic bowel wall thickening: is there a need for endoscopic evaluation? Int J Colorectal Dis (2011) 0.75
Extended daily dialysis does not affect the pharmacokinetics of anidulafungin. Int J Antimicrob Agents (2009) 0.75
[Principles of immunosuppression]. Pharm Unserer Zeit (2005) 0.75