PubRank

Qing-Xiang Amy Sang

Author PubWeight™ 37.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Androgen stimulates matrix metalloproteinase-2 expression in human prostate cancer. Endocrinology 2003 1.62
2 Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor. Cell Res 2006 1.51
3 The significance of focal myoepithelial cell layer disruptions in human breast tumor invasion: a paradigm shift from the "protease-centered" hypothesis. Exp Cell Res 2004 1.33
4 Activation of pro-gelatinase B by endometase/matrilysin-2 promotes invasion of human prostate cancer cells. J Biol Chem 2003 1.31
5 Endometase/matrilysin-2 in human breast ductal carcinoma in situ and its inhibition by tissue inhibitors of metalloproteinases-2 and -4: a putative role in the initiation of breast cancer invasion. Cancer Res 2004 1.13
6 Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26. J Biol Chem 2002 1.03
7 ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases. Curr Pharm Des 2009 0.98
8 The intermediate S1' pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling. J Biol Chem 2003 0.98
9 Active roles of tumor stroma in breast cancer metastasis. Int J Breast Cancer 2012 0.98
10 Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities. Biochem J 2004 0.98
11 Methodology and applications of disease biomarker identification in human serum. Biomark Insights 2007 0.97
12 Enhancing QM/MM molecular dynamics sampling in explicit environments via an orthogonal-space-random-walk-based strategy. J Phys Chem B 2011 0.95
13 Anion exchange fractionation of serum proteins versus albumin elimination. Anal Biochem 2007 0.93
14 A subset of in situ breast tumor cell clusters lacks expression of proliferation and progression related markers but shows signs of stromal and vascular invasion. Cancer Detect Prev 2005 0.92
15 ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein. J Biol Chem 2011 0.92
16 Intracellular activation of human adamalysin 19/disintegrin and metalloproteinase 19 by furin occurs via one of the two consecutive recognition sites. J Biol Chem 2002 0.91
17 Differentially expressed transcripts and dysregulated signaling pathways and networks in African American breast cancer. PLoS One 2013 0.90
18 Metastasis suppressors in human benign prostate, intraepithelial neoplasia, and invasive cancer: their prospects as therapeutic agents. Med Res Rev 2011 0.89
19 Isoelectric point-based prefractionation of proteins from crude biological samples prior to two-dimensional gel electrophoresis. J Proteome Res 2005 0.89
20 Expression of matrix metalloproteinase-26 and tissue inhibitor of metalloproteinase-4 in human normal cytotrophoblast cells and a choriocarcinoma cell line, JEG-3. Mol Hum Reprod 2002 0.88
21 Alteration in protein expression in estrogen receptor alpha-negative human breast cancer tissues indicates a malignant and metastatic phenotype. Clin Exp Metastasis 2010 0.85
22 Autolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activity. J Biol Chem 2002 0.85
23 Novel stromal biomarkers in human breast cancer tissues provide evidence for the more malignant phenotype of estrogen receptor-negative tumors. J Biomed Biotechnol 2011 0.84
24 Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors. Biochem J 2005 0.83
25 Calcium regulates tertiary structure and enzymatic activity of human endometase/matrilysin-2 and its role in promoting human breast cancer cell invasion. Biochem J 2007 0.81
26 Protein profiling of isolated leukocytes, myofibroblasts, epithelial, Basal, and endothelial cells from normal, hyperplastic, cancerous, and inflammatory human prostate tissues. J Cancer 2010 0.81
27 Expression of adamalysin 19/ADAM19 in the endometrium and placenta of rhesus monkey (Macaca mulatta) during early pregnancy. Mol Hum Reprod 2005 0.80
28 Prefractionation enhances loading capacity and identification of basic proteins from human breast cancer tissues. Anal Biochem 2010 0.80
29 C-lysine conjugates: pH-controlled light-activated reagents for efficient double-stranded DNA cleavage with implications for cancer therapy. J Am Chem Soc 2009 0.79
30 Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells. Ai Zheng 2009 0.78
31 Effects of detergents on catalytic activity of human endometase/matrilysin 2, a putative cancer biomarker. Anal Biochem 2009 0.77
32 Characterization of the phosphoproteome in androgen-repressed human prostate cancer cells by Fourier transform ion cyclotron resonance mass spectrometry. J Proteome Res 2011 0.77
33 Identification of Potential Glycoprotein Biomarkers in Estrogen Receptor Positive (ER+) and Negative (ER-) Human Breast Cancer Tissues by LC-LTQ/FT-ICR Mass Spectrometry. J Cancer 2012 0.77
34 Spatio-temporal expression of matrix metalloproteinase-26 in human placental trophoblasts and fetal red cells during normal placentation. Biol Reprod 2004 0.77
35 Developmental and hormonal regulation of meltrin beta (ADAM19) expression in mouse testes during embryonic and postnatal life. Life Sci 2006 0.77
36 The Anti-inflammatory Role of Endometase/Matrilysin-2 in Human Prostate Cancer Cells. J Cancer 2013 0.76
37 Protein engineering and properties of human metalloproteinase and thrombospondin 1. Biochem Biophys Res Commun 2002 0.76
38 Expression and implications of tissue inhibitor of metalloproteinases-4 in mouse embryo. Mol Hum Reprod 2003 0.76
39 Matrix metalloproteinase inhibitors based on the 3-mercaptopyrrolidine core. J Med Chem 2013 0.76
40 Protein Signatures in Human MDA-MB-231 Breast Cancer Cells Indicating a More Invasive Phenotype Following Knockdown of Human Endometase/Matrilysin-2 by siRNA. J Cancer 2011 0.75
41 Human coronary artery smooth muscle cell responses to bioactive polyelectrolyte multilayer interfaces. Biotechnol Res Int 2010 0.75
42 Efficient soluble expression of secreted matrix metalloproteinase 26 in Brevibacillus choshinensis. Protein Expr Purif 2013 0.75
43 Expression of tissue inhibitor of metalloproteinase-4 (TIMP-4) in endometrium and placenta of rhesus monkey (Macaca mulatta) during early pregnancy. Life Sci 2005 0.75