Published in Hypertension on June 01, 2002
Heritage Study--Genetics, Exercise and Risk Factors (HERITAGE) | NCT00005137
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension (2012) 1.30
Genes and human elite athletic performance. Hum Genet (2005) 1.28
Genetics of variation in serum uric acid and cardiovascular risk factors in Mexican Americans. J Clin Endocrinol Metab (2008) 1.13
Genetic effect on blood pressure is modulated by age: the Hypertension Genetic Epidemiology Network Study. Hypertension (2008) 1.10
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. J Biol Chem (2009) 1.06
A chromosome 11q quantitative-trait locus influences change of blood-pressure measurements over time in Mexican Americans of the San Antonio Family Heart Study. Am J Hum Genet (2007) 1.04
Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJxC3H/HeJ intercrosses. Mamm Genome (2007) 1.02
Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes. BMC Genet (2008) 0.92
Renal tubular transport and the genetic basis of hypertensive disease. Clin Exp Nephrol (2005) 0.85
Functional identification of the promoter of SLC4A5, a gene associated with cardiovascular and metabolic phenotypes in the HERITAGE Family Study. Eur J Hum Genet (2009) 0.84
Genome-wide linkage and positional candidate gene study of blood pressure response to dietary potassium intervention: the genetic epidemiology network of salt sensitivity study. Circ Cardiovasc Genet (2010) 0.82
Blood pressure and heart rate QTL in mice of the B6/D2 lineage: sex differences and environmental influences. Physiol Genomics (2008) 0.81
The insertion/deletion variation in the alpha2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetes. Cardiovasc Diabetol (2003) 0.80
Interaction of gender and body mass index (BMI) reveals evidence of linkage for hypertension in the Framingham Heart Study. BMC Genet (2003) 0.79
A novel SNP associated with nighttime pulse pressure in young-onset hypertension patients could be a genetic prognostic factor for cardiovascular events in a general cohort in Taiwan. PLoS One (2014) 0.77
Microsatellites and SNPs linkage analysis in a Sardinian genetic isolate confirms several essential hypertension loci previously identified in different populations. BMC Med Genet (2009) 0.77
Genome-wide linkage and positional association study of blood pressure response to dietary sodium intervention: the GenSalt Study. Am J Epidemiol (2012) 0.76
The sodium-bicarbonate cotransporter NBCe2 (slc4a5) expressed in human renal proximal tubules shows increased apical expression under high-salt conditions. Am J Physiol Regul Integr Comp Physiol (2015) 0.75
CATECHOLAMINES AND β2-ADRENOCEPTOR GENE EXPRESSION BEFORE AND AFTER MAXIMAL INCREMENTAL CYCLE TEST IN YOUNG ICE HOCKEY PLAYERS: RELATION TO WORK PERFORMED. Biol Sport (2013) 0.75
Somatic mutations affect key pathways in lung adenocarcinoma. Nature (2008) 30.02
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med (2007) 18.45
Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med (2004) 17.91
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Characterizing the cancer genome in lung adenocarcinoma. Nature (2007) 16.48
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
2011 Compendium of Physical Activities: a second update of codes and MET values. Med Sci Sports Exerc (2011) 13.10
American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc (2009) 8.89
Sitting time and mortality from all causes, cardiovascular disease, and cancer. Med Sci Sports Exerc (2009) 8.16
The human obesity gene map: the 2005 update. Obesity (Silver Spring) (2006) 7.17
Bariatric surgery and long-term cardiovascular events. JAMA (2012) 7.11
Admixture mapping for hypertension loci with genome-scan markers. Nat Genet (2005) 6.78
Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects. N Engl J Med (2012) 6.19
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Trends over 5 decades in U.S. occupation-related physical activity and their associations with obesity. PLoS One (2011) 4.21
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Is it time to change the way we report and discuss weight loss? Obesity (Silver Spring) (2009) 3.57
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Racial differences in abdominal depot-specific adiposity in white and African American adults. Am J Clin Nutr (2009) 3.39
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Short sleep duration is associated with reduced leptin levels and increased adiposity: Results from the Quebec family study. Obesity (Silver Spring) (2007) 3.23
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet (2009) 3.18
Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial. Lancet Oncol (2009) 3.14
Effects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO Study: a six-year randomized, controlled trial. Ann Intern Med (2004) 3.05
Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: the Swedish Obese Subjects, the HERITAGE Family Study, and a Memphis cohort. J Clin Endocrinol Metab (2002) 3.04
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Avoiding the high Bonferroni penalty in genome-wide association studies. Genet Epidemiol (2010) 2.79
Maintaining a high physical activity level over 20 years and weight gain. JAMA (2010) 2.78
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) (2010) 2.74
Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study. Lancet (2009) 2.73
Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study. Eur Heart J (2005) 2.69
Fenofibrate effect on triglyceride and postprandial response of apolipoprotein A5 variants: the GOLDN study. Arterioscler Thromb Vasc Biol (2007) 2.54
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A (2010) 2.47
The relationship of waist circumference and BMI to visceral, subcutaneous, and total body fat: sex and race differences. Obesity (Silver Spring) (2010) 2.47
Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs. J Appl Physiol (1985) (2010) 2.43
Genome-wide discovery of loci influencing chemotherapy cytotoxicity. Proc Natl Acad Sci U S A (2004) 2.37
Differences in left ventricular structure between black and white hypertensive adults: the Hypertension Genetic Epidemiology Network study. Hypertension (2004) 2.36
The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Med Sci Sports Exerc (2009) 2.30
The association between sleep duration and weight gain in adults: a 6-year prospective study from the Quebec Family Study. Sleep (2008) 2.30
Cognitive behavioral therapy and aerobic exercise for Gulf War veterans' illnesses: a randomized controlled trial. JAMA (2003) 2.26
Prevalence of risk factors for metabolic syndrome in adolescents: National Health and Nutrition Examination Survey (NHANES), 2001-2006. Arch Pediatr Adolesc Med (2009) 2.23
Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet (2002) 2.23
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes (2011) 2.09
A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. J Appl Physiol (1985) (2010) 2.07
Gender difference in blood pressure responses to dietary sodium intervention in the GenSalt study. J Hypertens (2009) 2.06
Profiles of sedentary behavior in children and adolescents: the US National Health and Nutrition Examination Survey, 2001-2006. Int J Pediatr Obes (2009) 2.05
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study. Circulation (2005) 2.03
Body mass index, waist circumference, and clustering of cardiovascular disease risk factors in a biracial sample of children and adolescents. Pediatrics (2004) 2.01
Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study. Diabetes (2008) 1.98
Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. Nat Genet (2010) 1.97
Effects of exercise training on glucose homeostasis: the HERITAGE Family Study. Diabetes Care (2005) 1.96
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation (2011) 1.96
Dose Response to Exercise in Women aged 45-75 yr (DREW): design and rationale. Med Sci Sports Exerc (2004) 1.92
Targeting the metabolic syndrome with exercise: evidence from the HERITAGE Family Study. Med Sci Sports Exerc (2003) 1.87
Utility of childhood BMI in the prediction of adulthood disease: comparison of national and international references. Obes Res (2005) 1.87
Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS One (2012) 1.84
Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm. PLoS Genet (2008) 1.80
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet (2012) 1.77
Combined influence of body mass index and waist circumference on coronary artery disease risk factors among children and adolescents. Pediatrics (2005) 1.76
CMDS: a population-based method for identifying recurrent DNA copy number aberrations in cancer from high-resolution data. Bioinformatics (2009) 1.73
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72