Published in Nucleic Acids Res on June 15, 2002
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Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms. Diabetologia (2007) 3.34
Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information. Am J Hum Genet (2004) 2.19
Incorporating genotyping uncertainty in haplotype inference for single-nucleotide polymorphisms. Am J Hum Genet (2004) 1.66
Locked nucleic acid (LNA) single nucleotide polymorphism (SNP) genotype analysis and validation using real-time PCR. Nucleic Acids Res (2004) 1.52
Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11. Genomics (2004) 1.17
Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity. Diabetes (2005) 1.13
The Invader assay for SNP genotyping. Mutat Res (2005) 1.11
A sensitive method for detecting variation in copy numbers of duplicated genes. Genome Res (2003) 0.94
INSIG1 influences obesity-related hypertriglyceridemia in humans. J Lipid Res (2009) 0.92
Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index. Pharmacogenomics (2008) 0.91
Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity. Hum Mol Genet (2004) 0.88
Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes. BMC Genet (2005) 0.87
Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent. Pharmacogenomics (2009) 0.86
Detection of genomic polymorphisms associated with venous thrombosis using the invader biplex assay. J Mol Diagn (2004) 0.86
Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels. Physiol Genomics (2010) 0.81
A novel procedure for genotyping of single nucleotide polymorphisms in trisomy with genomic DNA and the invader assay. Nucleic Acids Res (2008) 0.79
Automated SNP genotype clustering algorithm to improve data completeness in high-throughput SNP genotyping datasets from custom arrays. Genomics Proteomics Bioinformatics (2007) 0.79
Quantitative estimation of genetic risk for atypical scrapie in French sheep and potential consequences of the current breeding programme for resistance to scrapie on the risk of atypical scrapie. Genet Sel Evol (2010) 0.77
New approaches for genotyping paraffin wax embedded breast tissue from patients with cancer: the Iowa women's health study. J Clin Pathol (2005) 0.75
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High-throughput SNP genotyping by allele-specific PCR with universal energy-transfer-labeled primers. Genome Res (2001) 2.35
Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation. Genome Res (2000) 1.71
Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. Am J Hypertens (2000) 1.51
High-throughput genotyping assay approaches. Pharmacogenomics (2000) 1.43
Non-PCR-dependent detection of the factor V Leiden mutation from genomic DNA using a homogeneous invader microtiter plate assay. Mol Diagn (1999) 1.28
Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart, Lung and Blood Institute. J Hypertens (2000) 0.91
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A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
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Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA (2004) 23.69
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci U S A (2007) 11.85
Genome-wide association studies of 14 agronomic traits in rice landraces. Nat Genet (2010) 8.75
High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet (2005) 6.86
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature (2007) 6.77
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet (2008) 6.06
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Physical activity and weight gain prevention. JAMA (2010) 5.27
Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling. Sci Transl Med (2011) 4.91
A genomewide admixture map for Latino populations. Am J Hum Genet (2007) 4.71
Genomewide SNP variation reveals relationships among landraces and modern varieties of rice. Proc Natl Acad Sci U S A (2009) 4.65
Lung transplantation and survival in children with cystic fibrosis. N Engl J Med (2007) 4.57
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
Cardiac myosin activation: a potential therapeutic approach for systolic heart failure. Science (2011) 4.36
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Stereotactic body radiation therapy: the report of AAPM Task Group 101. Med Phys (2010) 3.87
Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas. Cancer Discov (2013) 3.64
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nat Genet (2011) 3.41
Use of a WHO-recommended algorithm to reduce mortality in seriously ill patients with HIV infection and smear-negative pulmonary tuberculosis in South Africa: an observational cohort study. Lancet Infect Dis (2011) 3.32
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genet (2010) 3.25
Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes (2007) 3.15
Matching strategies for genetic association studies in structured populations. Am J Hum Genet (2004) 3.13
Analysis of allelic differential expression in human white blood cells. Genome Res (2006) 3.07
MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res (2011) 3.03
High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol (2008) 2.92
Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1. Proc Natl Acad Sci U S A (2012) 2.89
HIV prevalence in China: integration of surveillance data and a systematic review. Lancet Infect Dis (2013) 2.82
Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus. Hepatology (2012) 2.63
A genomewide association study of skin pigmentation in a South Asian population. Am J Hum Genet (2007) 2.58
A decade's studies on metastasis of hepatocellular carcinoma. J Cancer Res Clin Oncol (2003) 2.50
Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat Immunol (2011) 2.47
Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet (2012) 2.41
Fibrin fragment D-dimer and the risk of future venous thrombosis. Blood (2002) 2.41
Culling and cattle controls influence tuberculosis risk for badgers. Proc Natl Acad Sci U S A (2006) 2.39
Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg (2011) 2.33
Noncoding sequences conserved in a limited number of mammals in the SIM2 interval are frequently functional. Genome Res (2004) 2.32
Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG. Circ Res (2003) 2.27
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature (2005) 2.27
HIV and syphilis prevalence among men who have sex with men: a cross-sectional survey of 61 cities in China. Clin Infect Dis (2013) 2.24
Telemedical retinopathy of prematurity diagnosis: accuracy, reliability, and image quality. Arch Ophthalmol (2007) 2.22
Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy. Circulation (2003) 2.17
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity (2012) 2.16
Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population. Diabetes (2008) 2.16
Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study. J Am Coll Cardiol (2008) 2.12
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell (2011) 2.10
BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature (2012) 2.00
Estimating the number of people living with HIV/AIDS in China: 2003-09. Int J Epidemiol (2010) 1.96
Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort. Circ Cardiovasc Genet (2009) 1.95
Blood 25-hydroxy vitamin D levels and incident type 2 diabetes: a meta-analysis of prospective studies. Diabetes Care (2013) 1.95
Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation. J Leukoc Biol (2007) 1.94
Segmental phylogenetic relationships of inbred mouse strains revealed by fine-scale analysis of sequence variation across 4.6 mb of mouse genome. Genome Res (2004) 1.93
Population-based incidence and prevalence of systemic lupus erythematosus: the Michigan Lupus Epidemiology and Surveillance program. Arthritis Rheumatol (2014) 1.91
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. Nat Genet (2013) 1.91
Extensively drug-resistant tuberculosis in california, 1993-2006. Clin Infect Dis (2008) 1.90
Cross-sectional validation of diabetes risk scores for predicting diabetes, metabolic syndrome, and chronic kidney disease in Taiwanese. Diabetes Care (2009) 1.88
A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program. Am J Hum Genet (2002) 1.87
Effects of thyroid hormone on the arrhythmogenic activity of pulmonary vein cardiomyocytes. J Am Coll Cardiol (2002) 1.87
Allele-specific differential expression of a common adiponectin gene polymorphism related to obesity. J Mol Med (Berl) (2003) 1.86
The genomics of selection in dogs and the parallel evolution between dogs and humans. Nat Commun (2013) 1.86
The development of HIV/AIDS surveillance in China. AIDS (2007) 1.86
Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma. J Hepatol (2007) 1.86
Mechanisms of arsenic-induced prolongation of cardiac repolarization. Mol Pharmacol (2004) 1.83
PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas. Genes Dev (2010) 1.82
Intelliject's novel epinephrine autoinjector: sharps injury prevention validation and comparable analysis with EpiPen and Twinject. Ann Allergy Asthma Immunol (2010) 1.81
Pentamidine-induced long QT syndrome and block of hERG trafficking. J Pharmacol Exp Ther (2004) 1.76
Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation. Proc Natl Acad Sci U S A (2011) 1.74
Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma. Clin Cancer Res (2007) 1.73
Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects. Clin Cancer Res (2010) 1.72
Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels. Hum Genomics (2004) 1.71
Fine mapping in 94 inbred mouse strains using a high-density haplotype resource. Genetics (2010) 1.71
A blood-based proteomic classifier for the molecular characterization of pulmonary nodules. Sci Transl Med (2013) 1.69
Propensity score-based comparison of long-term outcomes with 3-dimensional conformal radiotherapy vs intensity-modulated radiotherapy for esophageal cancer. Int J Radiat Oncol Biol Phys (2012) 1.65
mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.63
Enhancement of photocatalytic H2 evolution on CdS by loading MoS2 as Cocatalyst under visible light irradiation. J Am Chem Soc (2008) 1.62
Telemedical diagnosis of retinopathy of prematurity intraphysician agreement between ophthalmoscopic examination and image-based interpretation. Ophthalmology (2008) 1.60
Small-cell lung cancers in patients who never smoked cigarettes. J Thorac Oncol (2014) 1.60
Postoperative interferon alpha treatment postponed recurrence and improved overall survival in patients after curative resection of HBV-related hepatocellular carcinoma: a randomized clinical trial. J Cancer Res Clin Oncol (2006) 1.60
Factor analysis of metabolic syndrome using direct measurement of insulin resistance in Chinese with different degrees of glucose tolerance. Indian J Med Res (2008) 1.56
Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions. Clin Cancer Res (2012) 1.56
Genetic variants in the MRPS30 region and postmenopausal breast cancer risk. Genome Med (2011) 1.55
Migraine, weight gain and the risk of becoming overweight and obese: a prospective cohort study. Cephalalgia (2012) 1.55
Sex disparities in control and treatment of modifiable cardiovascular disease risk factors among patients with diabetes: Translating Research Into Action for Diabetes (TRIAD) Study. Diabetes Care (2007) 1.55
Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium. Hum Mol Genet (2011) 1.54
Comparison of interleukin-6 and C-reactive protein for the risk of developing hypertension in women. Hypertension (2006) 1.53
Estimating individual-level exposure to airborne polycyclic aromatic hydrocarbons throughout the gestational period based on personal, indoor, and outdoor monitoring. Environ Health Perspect (2008) 1.53
MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies. Cancer Epidemiol Biomarkers Prev (2007) 1.52
Change in pulse transit time and pre-ejection period during head-up tilt-induced progressive central hypovolaemia. J Clin Monit Comput (2007) 1.50
Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: a synthetic route to anticancer vaccine candidates. J Am Chem Soc (2006) 1.50
Prevalence and trend of hepatitis C virus infection among blood donors in Chinese mainland: a systematic review and meta-analysis. BMC Infect Dis (2011) 1.48
The plasma cell signature in autoimmune disease. Arthritis Rheumatol (2014) 1.47
Vasomotor symptoms and coronary artery calcium in postmenopausal women. Menopause (2010) 1.47
Variation in the FGFR2 gene and the effects of postmenopausal hormone therapy on invasive breast cancer. Cancer Epidemiol Biomarkers Prev (2009) 1.46