Published in Nat Med on June 17, 2002
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Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol (2008) 4.66
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Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels. Circ Res (2003) 2.01
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Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation. Immunity (2011) 1.75
Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development. Nat Immunol (2005) 1.75
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics (2007) 1.73
Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function. J Clin Invest (2006) 1.67
Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo. J Immunol (2002) 1.66
Accidental exposures to blood and body fluid in the operation room and the issue of underreporting. Am J Infect Control (2009) 1.66
Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor. J Exp Med (2004) 1.64
The role of antigenic peptide in CD4+ T helper phenotype development in a T cell receptor transgenic model. Int Immunol (2004) 1.63
Cutting edge: TLR2 directly triggers Th1 effector functions. J Immunol (2007) 1.61
C5a initiates the inflammatory cascade in immune complex peritonitis. J Immunol (2004) 1.57
CRTAM confers late-stage activation of CD8+ T cells to regulate retention within lymph node. J Immunol (2009) 1.57
CD16 promotes Escherichia coli sepsis through an FcR gamma inhibitory pathway that prevents phagocytosis and facilitates inflammation. Nat Med (2007) 1.57
DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc Natl Acad Sci U S A (2005) 1.53
Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J Exp Med (2007) 1.52
Cell-derived anaphylatoxins as key mediators of antibody-dependent type II autoimmunity in mice. J Clin Invest (2006) 1.51
An association between neutrophils and immunoglobulin free light chains in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2012) 1.51
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Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing. J Bone Miner Res (2012) 1.48
Dendritic cell subsets and immune regulation in the lung. Semin Immunol (2005) 1.48
Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200. J Immunol (2005) 1.47
Effective suppression of hippocampal seizures in rats by direct hippocampal cooling with a Peltier chip. J Neurosurg (2008) 1.45
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Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly. J Immunol (2002) 1.44
Relation between VE/VCO2 slope and maximum phonation time in chronic heart failure patients. Medicine (Baltimore) (2014) 1.39
Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high affinity anti-erythrocyte autoantibody. J Exp Med (2002) 1.39
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The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse. J Exp Med (2004) 1.35
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Use of multilocus variable-number tandem-repeat analysis for typing Mycobacterium avium subsp. paratuberculosis. J Clin Microbiol (2004) 1.31
Impaired antibody response causes persistence of prototypic T cell-contained virus. PLoS Biol (2009) 1.31
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28. Nat Immunol (2011) 1.30
Mycobacterium microti infection (vole tuberculosis) in wild rodent populations. J Clin Microbiol (2002) 1.30
Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation. Respir Res (2010) 1.27
Induction of lung emphysema is prevented by L-arginine-threonine-arginine. FASEB J (2008) 1.27
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NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling. Proc Natl Acad Sci U S A (2004) 1.25
Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection. J Allergy Clin Immunol (2007) 1.24
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Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci U S A (2009) 1.24
The Omp85 protein of Neisseria meningitidis is required for lipid export to the outer membrane. EMBO J (2003) 1.23
Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9. J Immunol (2008) 1.23
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Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation. Blood (2012) 1.23
The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation. Blood (2006) 1.23
Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor. J Cell Biol (2004) 1.22
Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease. Am J Physiol Heart Circ Physiol (2005) 1.22
Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management. Eur J Pharmacol (2011) 1.21
Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages. Respir Res (2006) 1.20
A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation. Immunity (2008) 1.20
Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine. J Immunol (2006) 1.19
Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Blood (2005) 1.18
The balance between plasmacytoid DC versus conventional DC determines pulmonary immunity to virus infections. PLoS One (2008) 1.18
Statins accelerate the onset of collagen type II-induced arthritis in mice. Arthritis Res Ther (2012) 1.18
Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function. J Clin Invest (2007) 1.18
Identification of distinct ligands for the C-type lectin receptors Mincle and Dectin-2 in the pathogenic fungus Malassezia. Cell Host Microbe (2013) 1.17
Non-digestible oligosaccharides reduce immunoglobulin free light-chain concentrations in infants at risk for allergy. Pediatr Allergy Immunol (2011) 1.17
Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development. Genes Cells (2002) 1.17
Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils. Nat Immunol (2008) 1.16
A critical role for the innate immune signaling molecule IRAK-4 in T cell activation. Science (2006) 1.16
Rapid and large amount of autocrine IL-3 production is responsible for mast cell survival by IgE in the absence of antigen. Blood (2004) 1.15
Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown. Am J Physiol Lung Cell Mol Physiol (2010) 1.15